This paper sets out to show that Kant’s account of cognition can be used to defend epistemic responsibility against the double threat of either being committed to implausible versions of doxastic voluntarism, or failing to account for a sufficiently robust connection between the will and belief. To support this claim, I argue that whilst we have no direct control over our beliefs, we have two forms of indirect doxastic control that are sufficient to ground epistemic responsibility: first, the capacity to (...) judge and doubt; and second, the ability to choose our epistemic maxims. It is because we have direct control over our capacity to judge as well as the epistemic principles that govern belief-acquisition that we have indirect control over the beliefs we thereby acquire. The interpretation of Kant I defend here thus allows us to account for the possibility of epistemic responsibility by providing a robust account of indirect doxastic voluntarism and thereby rendering direct doxastic voluntarism unnecessary. (shrink)

Development of Buddhist thought in India; 1. The Buddha’s suffering; 2. Practice and theory of no-self; 3. Kleśas and compassion; 4. The second Buddha’s greater vehicle; 5. Karmic questions; 6. Irresponsible selves, responsible non-selves; 7. The third turning: Yogācāra; 8. The long sixth to seventh century: epistemology as ethics; I. Perception and conception: the changing face ofultimate reality; II. Evaluating reasons: Naiyāyikas and Diṅnāga. III. Madhyamaka response to Yogācāra IV. Percepts and concepts: Apoha 1 ; V. Efficacy: Apoha 2 ; (...) VI. The path of the Bodhisattva; Epilogue; Background information; Appendix 1: The languages of Buddhism; Appendix 2: Intellectual context; Appendix 3: The Abhidharma. (shrink)

The emergence of analytic philosophy has often been seen as inaugurating a linguistic turn in philosophy, a turn with profound anti-metaphysical implications. Metaphysics and epistemology, on this view, were replaced by logic and philosophy of language as forming the basis of philosophy. But if we look at the work of the four founders of analytic philosophy, Frege, Russell, Moore and Wittgenstein, we find metaphysical conceptions at the heart of their endeavours. Frege, for example, regarded numbers and the truth-values as logical (...) objects, and the ontological distinction between concept and object was fundamental to his philosophy. Both Russell and Moore in their early work developed a realist view of propositions, and even when Russell abandoned the metaphysics of propositions in his later work, this was simply replaced by a metaphysics of facts. Wittgenstein, too, in the Tractatus, articulated a raft of theses that seem paradigmatically metaphysical, though their precise status has been controversial. In this paper I outline some of the key metaphysical conceptions of Frege, Russell, Moore and the early Wittgenstein, and explore the connections with their logical views, taking as my main example the problem of relational propositions. I end by addressing the question of the status of the metaphysical statements that Frege and Wittgenstein, in particular, found themselves making. (shrink)

This chapter contains sections titled: References.

This chapter provides a useful framework for thinking about public health ethical problems. It defines public health ethics as primarily concerned about the relationship between government, the individual and the community and how benefit and harm are distributed between individuals and the community. It suggests that public health ethics is part of medical ethics and bioethics and criticises the rights-based approach.

This chapter aims to reconstruct the philosophical motivation for the pudgalavāda or “Personalist” Buddhist view that the person is ultimately real. It argues that the ultraminimalism of the Abhidharma is too minimal to account for crucial features of personhood—especially its capacity to construct unities out of pluralities. The Buddhist Personalist insists that the individuation of person-constituting continua must be an ultimately real fact, not something we project onto or construct out of ultimate reality. That certain ultimate particulars really do belong (...) together, in a way they do not belong to other dharmas with which they may stand in causal-conditional relations, is a position not readily articulated within the Abhidharma metaphysical framework—yet the Pudgalavādin will not reject this framework, for it is only the person, and not other complex wholes, that must be ultimately real. (shrink)

This discussion note responds to Mark Colyvan’s claim that there is no easy road to nominalism. While Colyvan is right to note that the existence of mathematical explanations presents a more serious challenge to nominalists than is often thought, it is argued that nominalist accounts do have the resources to account for the existence of mathematical explanations whose explanatory role resides elsewhere than in their nominalistic content.

In this paper I describe the birth of Russell’s notion of a propositional function on 3 May 1902 and its immediate context and implications. In particular, I consider its significance in relation to the development of his views on analysis.

In a recent article in this journal I presented a sceptical argument about the current prominence of virtue ethics in nursing ethics. Daniel Putman has responded with a defence of the relevance of virtue in nursing. The present article continues this discussion by clarifying, defending, and expanding the sceptical argument. I start by emphasizing some features of the sceptical case, including assumptions about the nature of sceptical arguments, and about the character of both virtue ethics and nursing ethics. Then I (...) respond to objections of Putman's such as that, according to virtue ethics, virtue is relevant to the whole of a human life, including one's behaviour in a professional context; and that eudaimonia should be central in explaining and motivating a nurse's decision to enter the profession. Having argued that these objections are not compelling, I go on to discuss an interesting recent attempt to reassert the role of virtue ethics in the ethics of professions, including nursing. This centres on whether role‐specific obligations – e.g. the obligations that arise for a moral agent qua lawyer or mother – can be accommodated in a virtue ethics approach. Sean Cordell has argued that the difficulty of accommodating role‐specific obligations results in an ‘institution‐shaped gap’ in virtue ethics. He suggests a way of meeting this difficulty that appeals to the ergon of institutions. I endorse the negative point that role‐specific obligations elude virtue ethics, but argue that the appeal to the ergon of institutions is unsuccessful. The upshot is further support for scepticism about the virtue ethics approach to nursing ethics. I end by gesturing to some of the advantages of a sceptical view of virtue ethics in nursing ethics. (shrink)

High-spin states have been studied in Pr-135(59), populated through the Cd-116(Na-23,4n) reaction at 115 MeV, using the Gammasphere gamma-ray spectrometer. The negative-parity yrast band has been significantly extended to spin similar to 45 (h) over bar and excitation energy 21.5 MeV, showing evidence for several rotational alignments. The positive-parity yrast band of Ce-135(58), populated through the p4n channel of this reaction, was also populated to spin similar to 38 (h) over bar and excitation energy 18 MeV. Cranking calculations indicate that (...) these nuclei are soft with respect to the triaxiality parameter gamma and that several competing nuclear shapes occur at high spin. (shrink)

Medium- and high-spin states of Pr-134 were populated using the Cd-116(Na-23, 5n) reaction and studied with the GAMMASPHERE spectrometer. Several new bands have been found in this nucleus, one of them being linked to the previously observed chiral-candidate twin-band structure. The ground state of Pr-134 could be determined through establishing a level structure that connects the two previously known long-lived isomeric states. Unambiguous spin-parity assignments for the excited states could be performed based on the known 2(-) spin-parity of the ground (...) state combined with the present experimental data. Intrinsic single-particle configurations have been assigned to the newly observed bands on the basis of the measured B(M1)/B(E2) ratios, alignments, band-crossing frequencies, bandhead spins, the observed single-particle configurations in the neighboring nuclei, and taking into account the predictions of total Routhian surface and tilted-axis cranking calculations. (shrink)

The spatial dynamics of the optical emission from an array of 50 times 50 individual microcavity plasma devices is investigated. The array is operated in argon and argon-neon mixtures close to atmospheric pressure with an ac voltage. The optical emission is analysed with phase and space resolution. It has been found that the emission is not continuous over the entire ac period, but occurs once per half period. Each of the observed emission phases shows a self-pulsing of the discharge, with (...) several bursts of emission of fixed width and repetition rate. The number of emission bursts depends on applied voltage and frequency. Spatially resolved measurements prove that the emission bursts are formed by overlapping emission pulses from single discharge cavities. Intensity differences between positive and negative half-wave can be interpreted through spatially resolved measurements of single discharge cavities. (shrink)

High-spin states in the odd-odd N = Z nucleus Co-54 have been investigated by the fusion-evaporation reaction Si-28(S-32,1 alpha 1p1n)Co-54. Gamma-ray information gathered with the Ge detector array Gammasphere was correlated with evaporated particles detected in the charged particle detector system Microball and a 1 pi neutron detector array. A significantly extended excitation scheme of Co-54 is presented, which includes a candidate for the isospin T = 1, 6(+) state of the 1f(7/2)(-2) multiplet. The results are compared to large-scale shell-model (...) calculations in the fp shell. Effective interactions with and without isospin-breaking terms have been used to probe isospin symmetry and isospin mixing. A quest for deformed high-spin rotational cascades proved negative. This feature is discussed by means of cranking calculations. (shrink)

Two rotational bands have been identified and characterized in the proton-magic N = Z + 1 nucleus Ni-57. These bands complete the systematics of well-and superdeformed rotational bands in the light nickel isotopes starting from doubly magic Ni-56 to Ni-60. High-spin states in Ni-57 have been produced in the fusion-evaporation reaction Si-28(S-32, 2p1n)Ni-57 and studied with the gamma-ray detection array GAMMASPHERE operated in conjunction with detectors for evaporated light charged particles and neutrons. The features of the rotational bands in Ni-57 (...) are compared to those of neighbouring isotopes and interpreted by means of configuration-dependent cranked Nilsson-Strutinsky calculations. The two observed high-spin bands are considered signature partners and assigned to configurations with one 1g(9/2) proton and one 1g(9/2) neutron, resulting in an unambiguous understanding of the energetically favoured signature alpha = -1/2 band but a somewhat less satisfactory description of the signature alpha = +1/2 band. (shrink)

At moderate to high densities ungulates can impact negatively on forest crops and these may be managed by lethal control. In production forestry an understanding of the relationship between ungulate density, habitat-related factors and the incidence of tree damage may promote more efficient ungulate damage management than by lethal control alone. In plantation forests in the north cast of England, the incidence of conifer leader browsing by roe deer (Capreolus capreolus) was positively associated with an index of deer density (at (...) the site scale) and planted crop tree density (at the feeding patch scale) and was negatively associated with the relative abundance of palatable understorey vegetation (at the site scale). An interaction between the deer density index and palatable understorey browse abundance was positively associated with leader browsing. Coefficients from the optimal model were used to construct a browse probability surface across a matrix of values of deer dung density and palatable understorey vegetation abundance. This illustrated a very different relationship between dung density and conifer leader browsing probability across the various levels of palatable understorey vegetation abundance. From this we hypothesise that in areas of limited palatable understorey vegetation abundance, higher levels of culling may be required to achieve reductions in the incidence of conifer leader browsing than would be necessary in areas with moderate to high palatable understorey vegetation abundance. Improvements to understorey vegetation in concert with roe deer population control may enhance the efficiency of deer damage management in upland areas with nutrient-poor soils. Crown Copyright (C) 2008 Published by Elsevier B.V. All rights reserved. (shrink)

Human-wildlife conflicts are increasing throughout the world, principally due to a combination of human population growth, increased pressure on land and natural resources and climate change. Many human-wildlife conflicts stem from differences in objectives between various stakeholder groups, especially where the wildlife in question is a resource that can be exploited for economic or cultural benefit, or where the conservation of wildlife is at odds with human population growth or development pressure. Conflicts can be exacerbated by an incomplete understanding of (...) their causes and/or inappropriate intervention measures. Many traditional forms of intervention are also subject to increasing scrutiny and criticism from society. Here, we highlight the potential strategic benefits that can be made by an interdisciplinary approach to human-wildlife conflict situations, by integrating knowledge and understanding across the natural and social sciences. We also stress the potential tactical benefits from combining new approaches to management with more traditional ones. We emphasise the potential contribution of more recent developments in decision-making under conditions of limited data availability and uncertainty. Finally, we recommend that monitoring should play a more prominent role, both in assessing the role of stakeholder engagement in participatory decision-making and in contributing to the evidence base that will allow competing hypotheses about specific systems to be evaluated in an iterative manner. (shrink)

The review examines different essays from the context set by the idea of 'everyday aesthetics'. Confronted with the notion of "everyday aesthetics," one is immediately faced with some problems of definition. Such problems potentially threaten the viability of the everyday aesthetics project to extend the scope of philosophical aesthetics, so that, as Jonathan Smith suggests in his introduction to this collection of essays, "nothing in the everyday world (or at least very little) can be supposed devoid of the power to (...) excite an aesthetic response." "Everyday" can mean both "daily" and "ordinary," and while the two definitions often coincide in practice, there's no necessary connection: we can conceive the "daily" as remarkable, and the "ordinary" may not be a regular occurrence. If we focus on the aesthetics of the "daily," we might wonder which particular daily occurrences we can be properly said to experience aesthetically and if this means some reassessment of the category of "aesthetic objects" is required, given that "daily" is so often associated with the mundane, the nonaesthetic. Alternatively, if we conceive an aesthetics of the "ordinary" (with agreement on this classification of certain events and objects), then our notion of the "aesthetic" now seems vulnerable on either of two counts: (1) to claims of incoherence, given any agreement that exemplary aesthetic experience, at least, is fundamentally not of the "ordinary" (and never of the "ugly," of the stained, damp, cracked, and so on, in our domestic lives) but of an extraordinary class of events and objects called "art"; (2) to claims of cognitive and moral triviality (to amorality too, perhaps, that it's possible then, after Thomas de Quincy, to appreciate the way a murder is done), so that the aesthetic response is understood as merely a subjective, noncritical "look and feel" response to (almost) everything. It should be evident, then, that the notion of everyday aesthetics needs clarification before it can be of value to those interested in instructing or helping people to live aesthetic lives, and that such work of clarification gets to the very heart of philosophical aesthetics: answers to questions about what constitutes the "aesthetic" in life will inform all aspects of aesthetic inquiry, education, and practice, including the making and appreciating of artworks. (shrink)

Current debates about sex selection start from a paradox: on the one hand, the 'liberal' argument in favour of sex selection is often thought to be sound; but on the other hand there is widespread public opposition to sex selection. So it is worth spending some time examining the arguments against sex selection. Four different types of argument are identified: (i) religious arguments; (ii) consequentialist arguments, mainly concerning disturbance to the sex ratio; (iii) arguments to the effect that sex selection (...) involves a failure to respect the autonomy of a child; (iv) arguments to the effect that the motivation for sex selection brings with it an instrumental attitude to children not compatible with a child's need for unconditional acceptance and love. In the end the conclusion is reached that none of these arguments provide decisive arguments against the liberal thesis that sex selection ought to be permitted, especially where 'family balancing' is envisaged. In the light of this conclusion the issue of fetal sexing followed by selective feticide as a method of sex selection C is discussed. It is argued that sex selection is not in general a good reason for abortion, but that this practice may become unstoppable. Copyright (C) 2006 John Wiley & Sons, Ltd. (shrink)

The aim of this systematic review was to summarize and assess the quality of asthma intervention health economic studies from 2002 to 2007, compare the study findings with clinical management guidelines, and suggest avenues for future improvement of asthma health economic studies. Forty of the 177 studies met our inclusion criteria. We assessed the quality of studies using The Quality of Health Economic Studies validated instrument (total score range: 0-100). Six studies (15%) had quality category 2, 26 studies (65%) achieved (...) quality category 3, and the remaining eight (20%) studies were scored as the highest quality level, category 4. Overall, the findings from this review are in line with the Global Initiative for Asthma clinical guidelines. Many asthma health economic studies lacked appropriate long term time horizons to match the chronic nature of the disease and suffered from using effectiveness measures that did not capture all disease related risks and benefits. We recommend that new asthma simulation models: be flexible to allow for long term time horizons, focus on using levels of asthma control in their structure, and estimate both long term asthma specific outcomes like well-controlled time as well as generic outcomes such as quality adjusted survival. (shrink)

Background: Omalizumab, an anti-immunoglobulin E antibody, reduces exacerbations and symptoms in uncontrolled allergic asthma. The study objective was to estimate the costs and consequences of omalizumab compared to usual care from a US payer perspective. Methods: We estimated payer costs, quality-adjusted survival (QALYs), and the incremental cost-effectiveness ratio (ICER) of omalizumab compared to usual care using a state-transition simulation model that included sensitivity analyses. Every 2 weeks, patients could transition between chronic asthma and exacerbation health states. The best available evidence (...) informed the clinical and cost input estimates. Five years of omalizumab treatment followed by usual care was assumed to estimate a lifetime horizon. Omalizumab responders (60.5% of treated) were modeled as a separate scenario where nonresponders reverted back to usual care after 16 weeks of active treatment. Results: The mean lifetime discounted costs and QALYs were $83 400 and 13.87 for usual care and $174 500 and 14.19 for omalizumab plus usual care resulting in $287 200/QALY (95% interval: $219 300, $557 900). The ICER was $172 300/QALY when comparing omalizumab to usual care in the responder scenario. One-way sensitivity analyses indicated that the results were sensitive to the difference in treatment-specific utilities for the chronic state, exacerbation-associated mortality, omalizumab price, exacerbation rates, and response definition. Conclusions: The results suggest that adding omalizumab to usual care improves QALYs at an increase in direct medical costs. The cost-effectiveness of omalizumab is similar to other chronic disease biologics. The value increases when omalizumab response is used to guide long-term treatment. (shrink)

The Uncontrollability Thesis is that it is metaphysically impossible consciously to believe that p at will. I review the standard ways in which this might be explained. They focus on the aim or purpose of belief being truth. I argue that these don't work. They either explain the aim in a way which makes it implausible that the Uncontrollability Thesis is true, or they fail to justify their claim that beliefs should be understood as aimed at the truth. I further (...) argue that the explanations don't cut deep enough. Making the aim of truth internal to a state does not explain why we can't produce at will states without this feature but sharing these states' motivational role. I put forward a different explanation. I argue that consciousness makes manifest the attraction of the norm of truth. If we are consciously attending to the question of whether p, we cannot help but make a judgement in line with what the evidence gives us grounds for believing true. (shrink)

[First paragraphs] Reductionists about personal identity contend that there is nothing more to our survival than a series of causally related experiences and/or bodily continuities. Our belief in a separately existing self or subject of experiences is held to be unjustified, and we are recommended to reduce the conception of our own identity over time by jettisoning this belief. The particular form of reductionism that places the true view of our identity in a series of causally related experiences is usually (...) known as psychological reductionism or the psychological continuity approach. The version that gives prominence to the continuity of the body or human being, at least as it has been developed in recent years, is known as animalism or the biological approach. I shall concentrate on psychological reductionism because, of these two views, it seems to me the more intuitively appealing. But I shall also consider the animalist alternative, arguing that my main line of attack against psychological reductionism can be adapted against it. Both positions are mistaken in supposing that we have insufficient reason for believing in a separately existing subject of experiences. This conclusion is defended in the first section. In the second, I maintain that certain additional grounds that have been offered for accepting a reductionist position fail to do so. And, in the third, I examine a general objection to the conception of a subject of experiences that has been defended in the first two sections. (shrink)

In the Philebus, Plato reinterprets the traditional Olympian pantheon in terms of a nationalistic account of the cosmos which grounds the alternative to hedonism which Socrates defends. From the metaphysics of the Philebus, we can grasp 'Zeus' as a formal characteristic of the cosmos, required by any teleological account, and internal to the intelligible order of the universe, rather than standing outside of it. The universe is at once rationally ordered and good in virtue of the relation of reason to (...) goodness itself. Notwithstanding the rationalistic bias of Plato's theology, the 'good' is prior to and responsible for the divine. (shrink)

Two plausible claims seem to be inconsistent with each other. One is the idea that if one reasonably believes that one ought to fi, then indeed, on pain of acting irrationally, one ought to fi. The other is the view that we are fallible with respect to our beliefs about what we ought to do. Ewing’s Problem is how to react to this apparent inconsistency. I reject two easy ways out. One is Ewing’s own solution to his problem, which is (...) to introduce two different notions of ought. The other is the view that Ewing’s Problem rests on a simple confusion regarding the scope of the ought-operator. Then, I discuss two hard ways out, which I label objectivism and subjectivism, and for which G.E. Moore and Bishop Butler are introduced as historical witnesses. These are hard ways out because both of these views have strong counterintuitive consequences. After explaining why Ewing’s Problem is so difficult, I show that there is conceptual room in-between Moore and Butler, but I remain sceptical whether Ewing’s Problem is solvable within a realist framework of normative facts. (shrink)

A defence of the view that the introduction of transendental idealism, in the Dialectic of Aesthetic Judgment, plays a central role in resolving the antinomy which, as Kant contends, exists in our pure judgments of taste. It is further argued that the link that he holds to exist between the realms of nature and morality (or freedom) can only be successfully made out if transcendental idealism is accepted as underpinning our judgments concerning the beauties of nature.