© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

This book extends the concept of linguistic coordinate geometry using linguistic planes or semi-linguistic planes. In the case of coordinate planes, we are always guaranteed of the distance between any two points in that plane. However, in the case of linguistic and semi-linguistic planes, we can not always determine the linguistic distance between any two points. This is the first limitation of linguistic planes and semi-linguistic planes.

In this book, authors, for the first time, introduce the new notion of special subset linguistic topological spaces using linguistic square matrices. This book is organized into three chapters. Chapter One supplies the reader with the concept of ling set, ling variable, ling continuum, etc. Specific basic linguistic algebraic structures, like linguistic semigroup linguistic monoid, are introduced. Also, algebraic structures to linguistic square matrices are defined and described with examples. For the first time, non-commutative linguistic topological spaces are introduced. The (...) notion of a linguistic special subset of doubly non-commutative topological spaces of linguistic topological spaces is introduced in this book. (shrink)

"First published by Oxford University Press, 1916."--Title page verso.

"Bibliographical notes": pages [243]-244.

Das Buch widmet sich Komparatistischen Studien der interkulturellen Germanistik zu den Beziehungen zwischen Literaturen und anderen Künsten, Gattungen, Medien aus Mitteleuropa und aus anderen Kontinenten mit dem Ziel der Entwicklung einer Pluralität von Perspektiven auf gemeinsame Gegenstände 'Komparativer Ästhetik(en)'.

In this book the notion of semigroups under + is constructed using: the MOD natural neutrosophic integers, or MOD natural neutrosophic-neutrosophic numbers, or MOD natural neutrosophic finite complex modulo integer, or MOD natural neutrosophic dual number integers, or MOD natural neutrosophic special dual like number, or MOD natural neutrosophic special quasi dual numbers.

Principled discussions of civil rights became inherently less likely as a direct result of the observation by Earl Warren, in Brown v. Board of Education, that, respecting freedmen, “Education of Negroes was almost non-existent, and practically all of the race were illiterate,” and in proportion as that observation increasingly became the foundation of common opinion on the subject. Warren's observation was not true in any meaningful or non-trivial sense. Nevertheless, it served to perpetuate the myth of a backward people needing (...) help to catch up instead of the truth of a people being held back. That is the perspective – the disadvantaged group perspective – that ultimately infected all discussion of civil rights, even after the designation of so-called “disadvantaged groups” had been extended beyond American blacks. To define civil rights, we may well begin with what all mankind would likely recognize. Thus the dictionary definition of “civil rights” stands: “the rights that belong to all individuals in a nation or community touching property, marriage, and the like.” In that definition the term “rights” may be further expanded to mean “legitimate claims,” following the definition of right as law – as “a claim or title or interest in anything whatever that is enforceable by law.” This definition applies with minimal distinction of regimes intruding and, therefore, without the host of recent complications in the United States that create the impression that civil rights have something to do with pluralism. Previously, the generic definition was thought to exhaust the meaning of the term in the United States. (shrink)

(1983). The illustrations of birds in the Vatican manuscript of De arte venandi cum avibus of Frederick II. Annals of Science: Vol. 40, No. 6, pp. 597-634.

In this book the notion of MOD functions are defined on MOD planes. This new concept of MOD functions behaves in a very different way. Even very simple functions like y = nx has several zeros in MOD planes where as they are nice single line graphs with only (0, 0) as the only zero. Further polynomials in MOD planes do not in general follows the usual or classical laws of differentiation or integration.

A new dimension is given to modulo theory by defining MOD planes. In this book, the authors consolidate the entire four quadrant plane into a single quadrant plane defined as the MOD planes. MOD planes can be transformed to infinite plane and vice versa. Several innovative results in this direction are obtained. This paradigm shift will certainly lead to new discoveries.

Studies to neutrosophic graphs happens to be not only innovative and interesting, but gives a new dimension to graph theory. The classic coloring of edge problem happens to give various results. Neutrosophic tree will certainly find lots of applications in data mining when certain levels of indeterminacy is involved in the problem. Several open problems are suggested.