The saga of Ceyx, king of Trachis, begins at Met. 11.266 and continues to 11.748. Ceyx' adventures form the longest single episode in the Metamorphoses , slightly longer than the Phaethon legend . Three metamorphoses take place in the course of the Ceyx narrative. The first is that of Ceyx' brother Daedalion who is transformed into a hawk. The second transformation occurs in the course of the exiled Peleus' visit to Ceyx when a wolf attacks Peleus' cattle and sheep and (...) is eventually turned into stone. The third metamorphosis is that of Ceyx and his wife Alcyone into halcyons. The linking together of these three metamorphoses was entirely an Ovidian invention: it had never been done before. It is therefore important to see the Ceyx story as a whole, as it was put together by Ovid. Attention naturally concentrates on the most interesting episode in it – the Ceyx–Alcyone – but the Daedalion and Peleus episodes are integral parts of the narrative and not separate legends. The story is framed by the contrasting transformations of the two brothers. The fierce and bellicose Daedalion becomes a bird of prey . The gentle and uxorious Ceyx becomes a happily paired halcyon . It is ironic that we first meet Ceyx when he is mourning the transformation of his brother into a bird, since the same end awaits him. The brothers' characters are very different but their fates are similar. Ceyx' dealings with Peleus bring out the king of Trachis' hospitable, peace-loving, godly and husbandly qualities and give us a rounded and detailed picture of his personality to balance the developed character-study of his wife Alcyone which is to follow. The spotlight passes from Ceyx to Alcyone at Met. 11. 410. (shrink)

The saga of Ceyx, king of Trachis, begins at Met. 11.266 and continues to 11.748. Ceyx' adventures form the longest single episode in the Metamorphoses, slightly longer than the Phaethon legend. Three metamorphoses take place in the course of the Ceyx narrative. The first is that of Ceyx' brother Daedalion who is transformed into a hawk. The second transformation occurs in the course of the exiled Peleus' visit to Ceyx when a wolf attacks Peleus' cattle and sheep and is eventually (...) turned into stone. The third metamorphosis is that of Ceyx and his wife Alcyone into halcyons. The linking together of these three metamorphoses was entirely an Ovidian invention: it had never been done before. It is therefore important to see the Ceyx story as a whole, as it was put together by Ovid. Attention naturally concentrates on the most interesting episode in it – the Ceyx–Alcyone – but the Daedalion and Peleus episodes are integral parts of the narrative and not separate legends. The story is framed by the contrasting transformations of the two brothers. The fierce and bellicose Daedalion becomes a bird of prey. The gentle and uxorious Ceyx becomes a happily paired halcyon. It is ironic that we first meet Ceyx when he is mourning the transformation of his brother into a bird, since the same end awaits him. The brothers' characters are very different but their fates are similar. Ceyx' dealings with Peleus bring out the king of Trachis' hospitable, peace-loving, godly and husbandly qualities and give us a rounded and detailed picture of his personality to balance the developed character-study of his wife Alcyone which is to follow. The spotlight passes from Ceyx to Alcyone at Met. 11. 410. (shrink)

Neptunus et Apollo dicuntur Troiam muro cinxisse; his rex Laomedon uouit quod regno suo pecoris eo anno natum esset immolaturum. id uotum auaritia fefellit. alii dicunt †parum eum promisisse. The story that Neptune and Apollo together built the walls of Troy for Laomedon is well known from Homer. At the end of their year's service the perfidious king refused to pay the agreed wages. Ovid tells the familiar story in one of his transitional sections in the Metamorphoses. Hyginus' account poses (...) the textual problem indicated above. H. I. Rose comments on ‘parum’ as follows: ‘procul dubio corruptum hoc neque arridet Schmidtii coniectura promsisse. fuitne partum equarum? hoc enim plerumque narratur, equos quos a Ioue accepisset promisisse Laomedontem mercedis nomine…sed Herculi; quod facile ad deos mercennarios transferri potuit; atque non equos sed equas fuisse tradit Apollod. II, 104’. Rose rightly rejects Schmidt's emendation ‘promsisse’. ‘Promisisse’ has every sign of soundness and the difficulty lies, as Rose sees, with ‘parum’. Rose's own conjecture ‘partum equarum’, however, will not do. Apart from the oddity of the expression, one would need a good deal more persuasion than Rose offers to accept that the well-known promise of Zeus' horses which Laomedon made to Hercules was transferred from Hercules to Neptune and Apollo. There is no suggestion anywhere in the sources that Laomedon promised to give Neptune and Apollo the famous horses as payment for building the walls. (shrink)

Neptunus et Apollo dicuntur Troiam muro cinxisse; his rex Laomedon uouit quod regno suo pecoris eo anno natum esset immolaturum. id uotum auaritia fefellit. alii dicunt †parum eum promisisse. The story that Neptune and Apollo together built the walls of Troy for Laomedon is well known from Homer. At the end of their year's service the perfidious king refused to pay the agreed wages. Ovid tells the familiar story in one of his transitional sections in the Metamorphoses. Hyginus' account poses (...) the textual problem indicated above. H. I. Rose comments on ‘parum’ as follows: ‘procul dubio corruptum hoc neque arridet Schmidtii coniectura promsisse. fuitne partum equarum? hoc enim plerumque narratur, equos quos a Ioue accepisset promisisse Laomedontem mercedis nomine…sed Herculi; quod facile ad deos mercennarios transferri potuit; atque non equos sed equas fuisse tradit Apollod. II, 104’. Rose rightly rejects Schmidt's emendation ‘promsisse’. ‘Promisisse’ has every sign of soundness and the difficulty lies, as Rose sees, with ‘parum’. Rose's own conjecture ‘partum equarum’, however, will not do. Apart from the oddity of the expression, one would need a good deal more persuasion than Rose offers to accept that the well-known promise of Zeus' horses which Laomedon made to Hercules was transferred from Hercules to Neptune and Apollo. There is no suggestion anywhere in the sources that Laomedon promised to give Neptune and Apollo the famous horses as payment for building the walls. (shrink)

These lines come from the passage describing the mourning of the natural world following the death of Orpheus. A. D. Melville translates as follows:[‘ … ] and naiads wore,and Dryads too, their mourning robes of blackAnd hair dishevelled.’.

These lines come from the passage describing the mourning of the natural world following the death of Orpheus. A. D. Melville translates as follows: [‘ … ] and naiads wore, and Dryads too, their mourning robes of black And hair dishevelled.’.

In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in clinical assisted reproduction for preventing transmission of genetic defects. However, a more recent ethically and morally controversial development in PGT is its possible use in selecting IVF embryos for optimal intelligence quotient (IQ) and other non–disease-related socially desirable traits, such as tallness, fair complexion, athletic ability, and eye and hair colour, based on polygenic risk scores (PRS), in what (...) is referred to as PGT-P. Artificial intelligence (AI) and machine learning–based analysis of big data sets collated from genome sequencing of specific human ethnic populations can be used to estimate an individual embryo’s likelihood of developing such multifactorial traits by analysing the combination of specific genetic variants within its genome. Superficially, this technique appears compliant with Islamic principles and ethics. Because there is no modification of the human genome, there is no tampering with Allah’s creation (_taghyīr khalq Allah_). Nevertheless, a more critical analysis based on the five maxims of Islamic jurisprudence (_qawa'id fiqhiyyah_) that are often utilized in discourses on Islamic bioethics, namely _qaṣd_ (intention), _yaqın̄_ (certainty), _ḍarar_ (injury), _ḍarūra_ (necessity), and _`urf_ (custom), would instead reveal some major ethical and moral flaws of this new medical technology in the selection of non–disease-related socially desirable traits, and its non-compliance with the spirit and essence of Islamic law (shariah). Muslim scholars, jurists, doctors, and biomedical scientists should debate this further and issue a fatwa on this new medical technology platform. (shrink)

The “Tower of London” puzzle was adapted to tablet PCs to be used as a clinical bedside test. “Iso-problems”, a specific class of problems, require identical moves but ball colours are permuted. Thus difficulty is the same even if the appearance is different. We wanted to determine the impact of these as yet little-studied tasks and hypothesised that there may be a learning effect specific to them (the “iso-effect”). We interspersed a set of six iso-problems within one selection of 22 (...) tasks and analysed problem solving by 81 healthy adults (mean age 41.6 years). Participants showed learning across iso-problems (less time, fewer moves, increasingly efficient solutions). This effect was distinct from general learning, as was obvious from comparison with a series of non-isomorphic tasks. However, participants seem not to be aware of solving such problems. This “iso-effect” may be related to implicit memory, a domain that so far has not been assessed using the Tower of London. (shrink)

All-encompassing text examines every aspect of coma from neurochemistry, monitoring, and treatments to prognostic factors.

Patients in a vegetative state/ unresponsive wakefulness syndrome (VS/UWS) pose ethical dilemmas to those involved. Many conflicts occur between professionals and families of these patients. In the Netherlands physicians are supposed to withdraw life sustaining treatment once recovery is not to be expected. Yet these patients have shown to survive sometimes for decades. The role of the families is thought to be important. The aim of this study was to make an inventory of the professional perspective on conflicts in long-term (...) care of patients in VS/UWS. A qualitative study of transcripts on 2 Moral Deliberations (MD’s) in 2 cases of patients in VS/UWS in long-term care facilities. Six themes emerged: 1) Vision on VS/UWS; 2) Treatment and care plan; 3) Impact on relationships; 4) Feelings/attitude; 5) Communication; 6) Organizational aspects. These themes are related to professionals and to what families had expressed to the professionals. We found conflicts as well as contradictory feelings and thoughts to be a general feature in 4 of these themes, both in professionals and families. Conflicts were found in several actors: within families concerning all 6 themes, in nurse teams concerning the theme treatment and care plan, and between physicians concerning all 6 themes. Different visions, different expectations and hope on recovery, deviating goals and contradictory feelings/thoughts in families and professionals can lead to conflicts over a patient with VS/UWS. Key factors to prevent or solve such conflicts are a carefully established diagnosis, clarity upon visions, uniformity in treatment goals and plans, an open and empathic communication, expertise and understanding the importance of contradictory feelings/thoughts. Management should bridge conflicts and support their staff, by developing expertise, by creating stability and by facilitating medical ethical discourses. Shared compassion for the patient might be a key to gain trust and bridge the differences from non-shared to shared decision making. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

The COVID-19 pandemic caused an unprecedented and highly threatening, constrained, and confusing social and educational environment, we decided to expand the traditional focus of the extraneous load in Cognitive Load Theory acknowledging the psychological environment in which learning occurs. We therefore adapted and implemented principles of the CLT to reduce extraneous load for our students by facilitating their educational activities. Given previous empirical support for the principles of CLT, it was expected that the adoption of these principles might enable our (...) students to cultivate attitudes and skills across multiple domains such as online learning and presentation technologies, implementing and maintaining a “classroom atmosphere” in a virtual environment, participating in discussions among large online groups of students, facilitating group work, providing virtual office hours for students, and proactively planning for upcoming semesters. (shrink)

In describing the flawless regularity of developmental processes and the correlation between changes at certain genetic loci and changes in morphology, biologists frequently employ two metaphors: that genes ‘control’ development, and that genomes embody ‘programs’ for development. Although these metaphors have an admirable sharpness and punch, they lead, when taken literally, to highly distorted pictures of developmental processes. A more balanced, and useful, view of the role of genes in development is that they act as suppliers of the material needs (...) of development and, in some instances, as context‐dependent catalysts of cellular changes, rather than as ‘controllers’ of developmental progress and direction. The consequences of adopting this alternative view of development are discussed. (shrink)

With both the Roman Empire and contemporary scholarship as backdrop, this book contrasts the Imperial Platonism of Plotinus with Plato's own by distinguishing one as a master enlightening disciples, and the other as an Athenian teacher who taught students to discover the truth for themselves in the Academy.

Upshot: In our response we focus on five questions that point to important common themes in the commentaries: why start in wicked problems, what kind of system is a scientific perspective, what is the nature of second-order research processes, what does this mean for understanding interdisciplinary work, and how may polyocular research help make real-world decisions.

The ‘What Being the Parent of a New Baby is Like-Revised’ is an instrument designed to measure adaptation to parenthood. In the process of pilot testing and validating the WPL-R in a postpartum Dutch population, we became aware of the potentially sensitive nature of the measure. Despite the ethics committee waiving the invasive nature of the measure, we conducted a survey to explore its possible effect on women’s thoughts and emotions by using the Positive And Negative Affect Schedule to measure (...) changes associated with completion of the WPL-R. Two hundred and fifteen questionnaires were returned. Our findings indicated a change in PANAS scores, implying an intervening effect when using the WPL-R, in research. This raises the question of whether it is acceptable to use a questionnaire with postpartum women without any knowledge of the possible effect it may have, even though the ethics committee has approved the study and considers the measure to be non-invasive. (shrink)