In this paper, I offer both a brief study of Collingwood's conception of historical explanation and epistemological historicity, and an examination of the influence of Collingwood's work on the historical methodology of Quentin Skinner and on Gadamer's hermeneutic philosophy. Collingwood's work on the philosophy of history manifests a tension between the realist implications of the doctrine of reenactment and the logic of question and answer on the one hand, and, on the other, the constructionist tendency of the rest of his (...) work on the logic of historical inquiry and on the hermeneutic character of his more general conception of human historicity. This tension is displayed in the divergent interpretations of Collingwood by Quentin Skinner and Hans-Georg Gadamer, and in the inherent difficulties of each man's philosophy of history. I argue that the weaknesses of Skinner's methodological historicism are present already in his reading of Collingwood and reflect the difficulties inherent in understanding Collingwood as offering primarily a methodology of history. I also claim that Gadamer's hermeneutic philosophy, while presenting a more plausible reading of Collingwood, suffers from tensions similar to those within Collingwood's work between the logic of explanation and the logic of practical recommendation, and between the character of historical explanation and the character of philosophical understanding. (shrink)

This essay consists of an examination of the work of three thinkers who conceive of liberal education primarily in teleological terms, and, implicitly if not explicitly, attempt to offer some answer to the question: what does it mean to be fully human? John Henry Newman, T. S. Eliot, and Josef Pieper developed their understanding of liberal education from their own intellectual and religious experience, which was informed by a specifically Christian conception of the place of education in a fully developed (...) human life. I suggest that the strength of their understanding of liberal education derives from its connection to the various small cohesive religious communities to which they were connected. Nonetheless, this insularity was also the primary weakness because each writer ended universalising what was in fact a particular and unique cultural and religious experience instead of providing convincing proof of a single human nature with a single telos. I will contrast this teleological conception of liberal education with that of Michael Oakeshott and his student Kenneth Minogue, both of whom wrote about education in a post-religious era in which the earlier consensus had completely broken down. They both celebrated the variety of practices which human beings have invented for themselves over the past several centuries (and past several millennia), and did not appear to suffer from the lack of any unifying single human telos. I will suggest that their understanding of practice insulated them from the need for a single unifying telos. (shrink)

This essay consists of an examination of the work of three thinkers who conceive of liberal education primarily in teleological terms, and, implicitly if not explicitly, attempt to offer some answer to the question: what does it mean to be fully human? John Henry Newman, T. S. Eliot, and Josef Pieper developed their understanding of liberal education from their own intellectual and religious experience, which was informed by a specifically Christian conception of the place of education in a fully developed (...) human life. I suggest that the strength of their understanding of liberal education derives from its connection to the various small cohesive religious communities to which they were connected. Nonetheless, this insularity was also the primary weakness because each writer ended universalising what was in fact a particular and unique cultural and religious experience instead of providing convincing proof of a single human nature with a single telos. I will contrast this teleological conception of liberal education with that of Michael Oakeshott and his student Kenneth Minogue, both of whom wrote about education in a post-religious era in which the earlier consensus had completely broken down. They both celebrated the variety of practices which human beings have invented for themselves over the past several centuries (and past several millennia), and did not appear to suffer from the lack of any unifying single human telos. I will suggest that their understanding of practice insulated them from the need for a single unifying telos. (shrink)

Because of the public identification of both Michael Oakeshott and Leo Strauss as conservative political philosophers, there have been numerous comparisons of their political thought. Whatever similarities or differences that do exist between them, it is certainly true that they shared a keen interest in the history of political thought. However, they understood the character of history in widely divergent ways. In the following paper, I examine the way in which each writer understood the logic of historical explanation, and there (...) are two primary reasons for wanting to do so. First, there have been few examinations of either writer’s arguments concerning historical understanding, despite the stature of both as historians of political theory. Second, the differences between Oakeshott and Strauss on history are central to two fundamentally opposed ways of understanding the past, each of which has manifested itself in the contemporary practice of the history of political thought. I will argue that Strauss’s approach to the past is primarily a practical one and yields a concern with a legendary or mythical past constructed primarily to address contemporary political problems, and that his specific methodological propositions are either irrelevant to a specifically historical understanding of the past or inadequately argued and unconvincing. Conversely, I will suggest that Oakeshott offers a coherent and compelling account of the logic of historical understanding, which involves both a defense of the autonomy of historical explanation and an elaboration of the character of historical contextualism. (shrink)

This book provides an overview of some of the most important critics of “Enlightenment rationalism.” The subjects of the volume—including, among others, Burke, Kierkegaard, Nietzsche, T.S. Eliot, Wittgenstein, Heidegger, C.S. Lewis, Gabriel Marcel, Russell Kirk, and Jane Jacobs—do not share a philosophical tradition as much as a skeptical disposition toward the notion, common among modern thinkers, that there is only one standard of rationality or reasonableness, and that that one standard is or ought to be taken from the presuppositions, methods, (...) and logic of the natural sciences. The essays on each thinker are intended not merely to offer a commentary on that thinker, but also to place that thinker in the context of this larger stream of anti-rationalist thought. Thus, while this volume is not a history of anti-rationalist thought, it may contain the intimations of such a history. (shrink)

This collection, the first of its kind, brings together specially commissioned academic essays to mark fifty years since the death of John Kennedy Toole.

In preparation for the development of a rapid tissue donation programme, we surveyed healthcare providers in our institution about knowledge and attitudes related to RTD with lung cancer patients. A 31-item web based survey was developed collecting data on demographics, knowledge and attitudes about RTD. The survey contained three items measuring participants’ knowledge about RTD, five items assessing attitudes towards RTD recruitment and six items assessing HCPs’ level of agreement with factors influencing decisions to discuss RTD. Response options were presented (...) on a 5-point Likert scale. Ninety-one HCPs participated in the study. 66% indicated they had never heard of RTD prior to the survey, 78% rated knowledge of RTD as none or limited and 95.6% reported not having ethical or religious concerns about discussing RTD with patients. The majority were either not comfortable or not sure if they felt comfortable discussing RTD with cancer patients . 56.1% indicated their knowledge of RTD would play an integral role in their decision to discuss RTD with patients. 71.4% reported concerns with RTD discussion and the emotional state of the patient. Physicians and nurses play an important role in initiating conversations about recruitment and donation to research that can ultimately influence uptake. Increasing HCP knowledge about RTD is a necessary step towards building an RTD programme. Our study provides important information about characteristics associated with low levels of knowledge and practice related to RTD where additional education and training may be warranted. (shrink)

Burrowing mammals are ubiquitous on farms in South Africa and can hinder agricultural practices. This study explored farmer perspectives of these species, and specifically the factors that influence these perspectives. Forty-four farmers responded to a questionnaire that assessed their ecological knowledge of, tolerance towards and lethal management of burrowing mammals that occur on their farms. The results from generalised linear models showed that neither farmer age, nor level of education are accurate predictors of ecological knowledge, overall tolerance towards burrowers, or (...) their lethal management. Knowledge of burrowing mammals showed a significant relationship with tolerance, with more knowledgeable individuals displaying higher levels of tolerance. However, a farmer’s overall tolerance towards burrowing species did not affect the number of species managed. Our results also suggest that different values are attached to different species when it comes to lethal management. Thus, farmers commonly controlled the numbers of the problem rodent species, Highveld gerbil (Gerbilliscus brantsii) and Cape ground squirrel (Xerus inauris), but were less likely to manage black-backed jackal (Canis mesomelas) and warthog (Phacochoerus africanus), even when experiencing these as problematic. We suggest that the larger, more charismatic species possibly evoke more sympathy from farmers. Agro-ecosystems are likely to become increasingly important for conservation in the future, and we encourage continued studies on the environmental attitudes and approaches of agricultural practitioners as a means to understanding the current status and future trends in ecologically sustainable agriculture. (shrink)

The c‐myc proto‐oncogene is normally subject to complex regulation at the transcriptional and post‐transcriptional levels in proliferating and differentiating cells. It is activated in response to growth stimuli and generally, though not always, repressed in response to differentiation signals. Abnormal, deregulated c‐myc expression is a common feature of numerous malignancies and occurs by a variety of molecular mechanisms which probably reflect the existence of multiple factors responsible for its normal control. Here, I provide a detailed summary of recent progress and (...) current views on c‐myc gene regulation. (shrink)

Thomas Jefferson’s argument against long-term debt and his theory of usufruct are used to show why each generation is obligated to protect the independence of future generations. This argument forms the theory of “Jeffersonian generational independence.” The theory has wide implications for the environmental movement because most environmental problems result in limitations on the liberty of future generations. I compare and defend Jeffersonian generational independence from two alternatives including the investment theory raised by James Madison and the problem of generational (...) interdependence raised by John Passmore or Edmund Burke. When the obligation to protect the independence of future generations is taken seriously, liberalism can no longer reasonably be used to defend environmental exploitation, since such exploitation amounts to an attack on the liberty and independence which form its core values. (shrink)

El artículo aborda la refutación agustiniana del escepticismo, según se recoge en dos parábolas estudiadas con detalle en Contra Academicos. Señalando sus ideas y el influjo de Virgilio y Cicerón.

The North American wood frog, Rana sylvatica, endures seasonal whole‐body freezing during the winter and thawing during the spring without sustaining any apparent damage from ice or oxidative stress. Strategies from these frogs may solve the shortage of human donor organs, which is a multidisciplinary problem that can be alleviated by eliminating geographical boundaries. Rana sylvatica deploys an array of molecular and physiological responses, such as glucose production and microRNA regulation, to help it survive the cold. These strategies have been (...) adapted in the lab to impart cryotolerance in liver cells, and the non‐freezing supercooled storage of transplantable rat livers − milestones that have advanced the field toward cryopreserving human donor organs in the clinic. In this review, a case is presented for the use of non‐coding RNAs to decrease oxidative damage of donor organs by activating endogenous antioxidant systems prior to procurement. (shrink)

Community Partnered Participatory Research is grounded in the ethical principle of respect for persons participating in the research enterprise. The critical importance of respect for person...