The purpose of this paper is to offer a critical approach to the theory of autopoiesis in order to see how it challenges mainstream Darwinism. In the first part of the paper, I characterize Darwinism from the concepts of natural selection, heredity, reproduction, and evolution. This characterization is absolutely schematic, and I hope not controversial at all, since my aim is to provide a general background for the discussion of the rest of the paper. The second part presents the main (...) tenets of the theory of autopoiesis, also paying special attention to the concepts of natural selection, heredity, reproduction, and evolution. The third and final part considers some criticisms that have been directed against the theory and suggests some new ones. As I said, my intention is to offer a critical approach, so that I pretend to assess neither autopoiesis nor Darwinism. The assessment, it seems to me, would be a matter of scientific debate—not properly of philosophy. Therefore, given that my approach attempts to be a conceptual clarification, my contribution to the contemporary debate about Darwinism is twofold. On the one hand, I show that conceptually autopoiesis constitutes an important challenge to Darwinism, but on the other, I also show that some fundamental aspects of the theory appear to be both epistemologically and empirically problematic, which perhaps helps to understand why autopoiesis is not widely accepted in mainstream Darwinism. (shrink)

Existe una tendencia en los estudios CTS contemporáneos a contraponer modelos deficitarios y modelos democráticos de divulgación científica. Esta contraposición suele apoyarse en lo que se conoce como el nuevo contrato social sobre ciencia y tecnología, y puede formularse así: mientras el viejo contrato social implicaba un modelo deficitario de divulgación científica, el nuevo contrato social implica un modelo democrático, que no es deficitario. En este artículo, defiendo la tesis de que dicha contraposición está mal fundada por dos razones. En (...) primer lugar, el nuevo contrato social es compatible con diversos modelos democráticos de divulgación científica, y estos modelos no son compatibles entre sí necesariamente. En segundo lugar, algunos de estos modelos democráticos pueden calificarse también como deficitarios. Esto deja abierta la pregunta de cómo entender la divulgación científica en el marco del nuevo contrato social sobre ciencia y tecnología. (shrink)

Kepler is mainly known among historians of science for his astronomical theories and his approaches to problems having to do with philosophy of science and ontology. This paper attempts to contribute to Kepler studies by providing a discussion of a topic not frequently considered, namely Kepler’s theory of the soul, a general theory of knowledge whose central problem is what makes knowledge possible, rather than what makes knowledge true, as happens in the case of Descartes’s and Bacon’s epistemologies. Kepler’s theory (...) consists of four issues: the theory of the different sorts of soul—that is, the human soul, the animal soul, the vegetable soul, and the Earth soul—concerning their faculties, the differences and the resemblances emerging among them, the relation they maintain with their own bodies and the world, and the distinction soul–world. The paper discusses these issues from a historical perspective, that is, it reconstructs the way they appear in three periods of Kepler’s career: the period prior to the publication of the Mysterium cosmographicum, the period from 1596 to 1611, and the period of the Harmonices mundi libri V. Finally, Kepler’s epistemology is briefly contrasted with Descartes’s and Bacon’s in order to suggest that Kepler’s could be seen as a third way to understand the philosophical origins of Modernity.Keywords: Johannes Kepler; René Descartes; Francis Bacon; Anima; Force; Animism. (shrink)

This article develops an understanding of Luther which runs counter to the classic Roman Catholic image of him as zealotic iconoclast. In Luther's life these discourses mark the zenith of his influence and spiritual authority. The experience of the radical movement in Wittenberg decisively formed Luther's reforming activities; in the area of the reorganization of the Mass, where the safety of conscience and Christian liberty were involved, he became cautious and slowed the development rather than pushed it forward. Furthermore, the (...) pluralistic arrangements of the Lutheran orders of service are ultimately the unavoidable consequence of those theological principles as contained in this series of sermons. (shrink)

I outline a holistic normative approach to migration in which I identify the major considerations that should be taken into account in formulating just migration policies. I argue that migration is basically an issue of global justice and that the basic interests of all parties significantly affected by migration should be taken into account in an adequate normative approach to this issue. I also maintain that an open borders policy does not allow for the strategic use of labor migration as (...) a tool to address global inequalities and that it neglects legitimate concerns that liberal egalitarians should have for the most vulnerable individuals in developing countries. (shrink)

In this essay, I propose a definition of multiculturalism and provide pragmatic and theoretical reasons for accepting the multicultural perspective when it is defined in this manner. In addition, I discuss and defend three sociopolitical principles to which we are committed in adopting the multicultural perspective and discuss some of the concrete social and institutional changes needed for implementing these principles.

La valoración filosófica del pensa-miento cusano ha sido el resultado de pacientesinvestigaciones que lograron liberar su imagen deapresuradas y polêmicas calificaciones. Ennuestra ponencia procuramos poner de manifies-to un aspecto de la presencia concreta del pen-samiento neoplatónico en el cusano, En lo que eimismo Nicolás considera "un ejercicio del enten-dimiento” nos muestra cómo asume y asimila lavertiente neoplatónica para ofrecernos una mejorcomprensión de un tema caro a la tradiciónteológica: el sentido y significado del términoprincípio dicho no sólo de Dios sino también (...) deCristo. (shrink)

Rare disease are those pathologies that affect a reduced proportion of the population. For this reason, the research on their causes and mechanisms, which is essential to find a way to treat or prevent them, is insufficient. This causes that the patients report a lack of coverage by the health system and the social discrimination that suffering one of these pathologies entails. Among rare diseases, we find the so-called prion diseases or transmissible spongiform encephalopathies. Although they are relatively well-known due (...) to the health crisis provoked by the “mad cow disease” at the end of the last century, there are still many uncertainties about these disorders that affect both animals and humans. This monograph aims at bringing to light the fascinating history and the diversity of prion diseases, which shook the foundations of the biology known before the 1980s by bringing out a new and puzzling type of infectious agent: prions. (shrink)

Una de las mayores revoluciones dela época contemporánea en el plano jurídicomorales la universalización de los derechoshumanos. Esta nueva realidad que vive la Humanidadai término dei II Milenio es fruto de unalarga conquista colectiva, pues todas las civilizacionesse fundan en sistemas de creencias quetratan de liberar ai hornbre de las necesidadesmás elementales de.la condición humana. Sinembargo, han sido la cultura occidental la quemás se ha distinguido en la lucha por las libertades,como ha quedado recogido en la literaturadei Antiguo y dei (...) Nuevo Testamento y en las delos gríegos y romanos. Ciertarnente no se trataaún de los derechos subjetivos, pero la idea denaturaleza humana inspira los prirneros intentosde elevar ai plano jurídico y politico los deseoslegítimos de libertad. En el siglo XII surgen lasprirneras ciudades "libres" y se reconoce lainiciativa de mercado, pero, sobre todo, e! respetoa la conciencia es objeto de reflexión preferentepor parte de los juristas y de los teólogos. SantoTomás de AqUino elabora e! concepto de naturalezacreada, pero suficiente en cuanto a sus fines.Por último, e! descubrirniento de América obliga alos teólogos espaiioles a sacar las consecuenciasde la idea de naturaleza humana en el contextosocio-político de la Conquista. (shrink)

Juan Luis Vives: Humanistic Logic versus Nominalistc Logic. In this work we study an aspect of the Humanism of Juan Luis Vives: his critique to the Nominalistic Logic. According to the Spanish philosopher, Grammar and Rhetoric were not separable from Dialectic. Perhaps Juan Luis Vives did not understand very well the sense of the Nominalistic Logic. Nevertheles his contribution to the humanictic Logic was quite considerable.

The occurrence of the novel severe acute respiratory syndrome coronavirus-2 at the end of 2019 comes along with many challenges. Besides worry for one’s own health and the well-being of the family, all measures applied to limit the spread of the coronavirus affected daily life. School closures, economic shutdown and contact restrictions have led to high levels of stress. The impact on health and families has been widely discussed. However, population-based data are scarce. Here, we have assessed health, quality of (...) life and intrafamilial relations depending on the COVID-19 pandemic. Using a three-step random-route approach, a population-based sample of 2,515 persons was recruited during the second COVID-19 wave in Germany in winter 2020/21. While the majority of participants reported no change in their health status and the relationship with their partner and children, more than half of participants reported a decreased quality of life since the beginning of the pandemic. Female gender, age above 60 years, a low household income, not living with a partner and the experience of childhood adversity were associated with a higher risk for a worsening of health, quality of life and intrafamilial relations. These had already been well-established risk factors ahead of the pandemic. In order to avoid further increase of inequality in our society and more devastating impact of the pandemic on health and intrafamilial relations, low-level support and intervention programs are urgently needed. (shrink)

Este artigo tem como objetivo principal apresentar uma reconstruçáo lógico-conceitual e avaliaçáo de três argumentos de Skinner para a tese de que os termos psicológicos comuns sáo, em geral, inadmissíveis em análise do comportamento (a tese da inadmissibilidade). Começamos fazendo uma revisáo da abordagem de tais termos sustentada por Skinner, particularmente sua abordagem das categoriais de termos psicológicos disposicionais. Muito dela é aqui aceito, mas adotamos, como hipótese de trabalho, um desacordo com a premissa de Skinner de que eles sejam (...) irremediavelmente mentalistas. Nossa análise mostra que, se esta hipótese estiver correta, entáo os argumentos analisados náo resultam ser inteiramente plausíveis; e, embora a opçáo do autor seja plenamente aceitável, também o é uma (em princípio) opçáo alternativa, que explore os valores heurísticos de tais termos (sem incorporá-los ao vocabulário de base) para a descoberta de padrões comportamentais e seus contextos, em ambientes abertos de pesquisa. Um objetivo colateral deste artigo é mostrar o equívoco de duas suposições muitas vezes assumidas em filosofia da mente sobre o behaviorismo radical: a de que ele náo tem uma abordagem relevante sobre o funcionamento dos termos em questáo e a de que sua tese da inadmissibilidade se baseia em premissas verificacionistas. (shrink)

El Salmo 2 ha ser - vido a los primeros cristianos para comprender y expresar la identi- dad y la misión de Jesús. Partiendo del estudio del texto en sí mismo, este artículo busca comprenderlo desde dos puntos de vista: el de su producción literaria y el de su recepción en el Canon. Para el autor, el texto actual resulta de un largo proceso de elaboración lite- raria, en la que se han construido y refinado toda una serie de concep- (...) ciones mientras que otras han sido relegadas. En este contexto, Sal 2 junto con los otros salmos reales constituyen un puente entre la legi- timación monárquica preexílica y la esperanza mesiánica postexílica. (shrink)

Clonal disease is often regarded as almost synonymous with cancer. However, it is becoming increasingly clear that our bodies harbor numerous mutant clones that are not tumors, and mostly give rise to no disease at all. Here we discuss three somatic mutations arising within the hematopoietic system: BCR‐ABL, characteristic of chronic myeloid leukemia; mutations of the PIG‐A gene, characteristic of paroxysmal nocturnal hemoglobinuria; the V617F mutation in the JAK2 gene, characteristic of myeloproliferative diseases. The population frequencies of these three blood (...) disorders fit well with a hierarchical model of hematopoiesis. The fate of any mutant clone will depend on the target cell and on the fitness advantage, if any, that the mutation confers on the cell. In general, we can expect that only a mutation in a hematopoietic stem cell will give long‐term disease; the same mutation taking place in a cell located more downstream may produce just a ripple in the hematopoietic ocean. (shrink)

Natural Law is considered by many jurists an ambiguous concept. In this article we offer a concise history of ancient and mediaeval Natural Law as well as how it is present in the modern Bills of Human Rights. In the Natural Law it is convenient to distinguish what is caducous from that still valid.

With right-wing-extremist and -populist parties and movements on the rise throughout the world, the concept of authoritarianism has proven to be particularly valuable to explain the psychological underpinnings of these tendencies. Even though many scales to measure the different dimensions of authoritarianism exist, no short screening instrument has been tested and validated on a large scale so far. The present study examines the psychometric properties of the screening instrument Authoritarianism – Ultrashort in three representative German samples. Using exploratory and confirmatory (...) factor analysis, the A-US demonstrated acceptable internal consistency. Model fit was good and correlations with related constructs indicated convergent validity in both samples. Construct validity was demonstrated using the original version of the scale. The instrument proved to be invariant across sex, employment status, and education, but not across different age groups. Finally, the analyses showed that differences in the A-US are associated with sociodemographic variables. Potential causes and effects of these findings are discussed. Based on these results, the A-US proved to be a valuable and highly efficient tool to screen for authoritarian tendencies. (shrink)

BackgroundBehavioral and physiological regulation in early life is crucial for the understanding of childhood development and adjustment. The autonomic nervous system is a main player in the regulative system and should therefore be modulated by the quality of interactive behavior of the caregiver. We experimentally investigated the ANS response of 18–36-month-old children in response to the quality of maternal behavior during a mother–child-interacting paradigm.MethodEighty mothers and their children came to our laboratory and took part in an experimental paradigm, consisting of (...) three episodes: a resting phase, a structured play phase, and a free play situation between mothers and their child. Children’s and mother’s heart rate, the sympathetic nervous system activity via the pre-ejection period and the left ventricular ejection time, and the parasympathetic nervous system activity via the respiratory sinus arrhythmia were continuously measured by an electrocardiogram. Maternal sensitivity of interactive behavior was assessed by using the Emotional Availability Scales.ResultsChildren of mothers with insensitive behavior had a significantly lower RSA at baseline, showed a lack of RSA withdrawal during structured and free play, and had shorter LVET across all episodes compared to children of sensitive mothers.ConclusionOur findings depict the influence of low-quality maternal interaction on the child’s ANS regulation, in calm and more stressful play situations. The overall higher SNS mode with impaired PNS reactivity may negatively influence child’s ANS homoeostasis, which may result in a long-term impact on mental and physical wellbeing. Further, the maternal sensitivity may function as a buffer for the stress response of their child. These results could serve as a basis for the development of appropriate psychoeducational programs for mothers of low sensitivity in their interaction with the child. (shrink)

Capacity and competence in the field of child and adolescent psychiatry are complex issues, because of the many different influences that are involved in how children and adolescents make treatment decisions within the setting of mental health. This article will examine some of the influences which must be considered, namely: developmental aspects, the paradoxical relationship between the need for autonomy and participation and the capacity of children, family psychiatry, and the duty of care towards children and adolescents. The legal frameworks (...) relevant to consideration of consent and competence will be briefly considered, as well as some studies of children's consent, participation and competence. A case vignette will be used as a focus to consider the complexity of the issue of competence in child and adolescent psychiatry, in the particular mental disorder of anorexia nervosa. (shrink)

Modern theories of authoritarianism have stressed the importance of threat to the expression of authoritarian attitudes and intolerance. Arguably, authoritarian tendencies may have increased during COVID-19 pandemic, a major threat to life and security. One issue arising when comparing mean scores is that of measurement invariance. Meaningful comparisons are only possible, if latent constructs are similar between groups and/or across time. This prerequisite is rarely ever tested in research on authoritarianism. In this study, we aim to analyze the short scale (...) for authoritarianism KSA-3 by investigating its measurement invariance on two levels and latent mean changes using two German representative samples. Specifically, we look at differences before and during the pandemic. While measurement invariance holds across both levels in all conditions, we find a decrease in latent means in 2020, contrary to expectations and established theories. Moreover, latent means differ with regard to gender, education, and east–west Germany. We conclude that analyses of latent means and measurement invariance instead of mean comparisons with composites should become the standard. Future studies should focus on threat as a moderator between authoritarianism and intolerance, and on possible interactions with context variables. (shrink)

Die Schweigepflicht, einer der Grundpfeiler medizinischer Ethik, spielt in der aktuellen Diskussion um die Verbesserung des Kinderschutzes eine zentrale Rolle. Unklare und mehrdeutige gesetzliche Regelungen und Handlungsanweisungen, wie mit Anhaltspunkten für eine Kindeswohlgefährdung umzugehen ist, wenn die Sorgeberechtigten eine weitergehende Hilfe ablehnen, werden als Hindernis für einen wirksamen Kinderschutz betrachtet. Aus der schwer durchschaubaren Rechtslage resultieren für Angehörige der Gesundheitsberufe regelmäßig Handlungsunsicherheiten, die im Einzelfall notwendige Hilfe verzögern oder gar verhindern könnten. Neue Gesetze auf Länderebene haben deshalb im Sinne eines (...) verbesserten Kinderschutzes eine Erhöhung der Rechtssicherheit sowie eine Förderung der Vernetzung der beteiligten Akteure zum Ziel. Wenn auch einigen der Gesetze ein gewisses Klarstellungspotenzial zugebilligt werden kann, ist doch im Augenblick ihr Beitrag zu mehr Rechtssicherheit im Umgang mit Kinderschutzfällen noch als sehr eingeschränkt zu betrachten. Ein Bundesgesetz, welches die Intention hatte, die heterogenen Landesnormen durch eine bundeseinheitliche Regelung zu ersetzen, ist wenigstens in der letzten Legislaturperiode gescheitert. (shrink)

ZusammenfassungDie Schweigepflicht, einer der Grundpfeiler medizinischer Ethik, spielt in der aktuellen Diskussion um die Verbesserung des Kinderschutzes eine zentrale Rolle. Unklare und mehrdeutige gesetzliche Regelungen und Handlungsanweisungen, wie mit Anhaltspunkten für eine Kindeswohlgefährdung umzugehen ist, wenn die Sorgeberechtigten eine weitergehende Hilfe ablehnen, werden als Hindernis für einen wirksamen Kinderschutz betrachtet. Aus der schwer durchschaubaren Rechtslage resultieren für Angehörige der Gesundheitsberufe regelmäßig Handlungsunsicherheiten, die im Einzelfall notwendige Hilfe verzögern oder gar verhindern könnten. Neue Gesetze auf Länderebene haben deshalb im Sinne eines (...) verbesserten Kinderschutzes eine Erhöhung der Rechtssicherheit sowie eine Förderung der Vernetzung der beteiligten Akteure zum Ziel. Wenn auch einigen der Gesetze ein gewisses Klarstellungspotenzial zugebilligt werden kann, ist doch im Augenblick ihr Beitrag zu mehr Rechtssicherheit im Umgang mit Kinderschutzfällen noch als sehr eingeschränkt zu betrachten. Ein Bundesgesetz, welches die Intention hatte, die heterogenen Landesnormen durch eine bundeseinheitliche Regelung zu ersetzen, ist wenigstens in der letzten Legislaturperiode gescheitert. (shrink)