Effectiveness is a key criterion in assessing the justification of antibiotic resistance interventions. Depending on an intervention’s effectiveness, burdens and costs will be more or less justified, which is especially important for large scale population-level interventions with high running costs and pronounced risks to individuals in terms of wellbeing, integrity and autonomy. In this paper, we assess the case of routine hospital screening for multi-drug-resistant Gram-negative bacteria (MDRGN) from this perspective. Utilizing a comparison to screening programs for Methicillin-Resistant Staphylococcus aureus (...) (MRSA) we argue that current screening programmes for MDRGN in low endemic settings should be reconsidered, as its effectiveness is in doubt, while general downsides to screening programs remain. To accomplish justifiable antibiotic stewardship, MDRGN screening should not be viewed as a separate measure, but rather as part of a comprehensive approach. The program should be redesigned to focus on those at risk of developing symptomatic infections with MDRGN rather than merely detecting those colonised. (shrink)

CHAPTER ONE THE WORLD AS WILL TO POWER /. What there is for Nietzsche Any philosophical system which claims to be at all comprehensive must answer, ...

This book deals with contemporary epistemological questions, connecting Educational Philosophy with the field of Science- and Technology Studies. It can be understood as a draft of a general theory of world-disclosure, which is in its core a distinction between two forms of world-disclosure: experiment and exploration. These two forms have never been clearly distinguished before. The focus lies on the experimental form of world-disclosure, which is described in detail and in contrast to the explorational form along the line of twenty-one (...) characteristics, which are mainly derived from empirical studies of experimental work in the field of natural sciences. It can also be understood as an attempt to integrate elements of the Anglo-Saxon Philosophy of Science with elements of the German tradition of Educational Philosophy. This is also reflected in the style of writing. In accordance to the content-level of the book, the argument for experimental forms of world-disclosure is written in an essayistic, readable style, which can be understood as an experimental form of writing. This book is a translation of the doctoral thesis 'Experiment und Exploration. Bildung als experimentelle Form der Welterschließung' (summa cum laude). The thesis was published in German in 2010 by Transcript (Bielefeld) in the series called 'Theorie Bilden', edited by Prof. Dr. Hannelore Faulstich-Wieland, Prof. Dr. Hans-Christoph Koller, Prof. Dr. Karl-Josef Pazzini and Prof. Dr. Michael Wimmer. (shrink)

Ethical theories have been largely focused on finding and clarifying certain amoral principles. However fruitful the communication of moral principles for providing orientation in modern society might be, a serious omission has been made in that the problem of implementation is not addressed. Two fundamental question have neither been raised nor answered: Why should self‐interested individuals follow the proposed moral principles in their daily conduct? Are societal institutions of such a design that is in the power of the individuals to (...) follow these moral principles? It is shown in this article that an economic theory of morals does systematically address these two questions and therefore provides a firm basis for discussing the possibilities and boundaries of following the moral principles inherent in the long history of moral philosophy. (shrink)

Ethical theories have been largely focused on finding and clarifying certain amoral principles. However fruitful the communication of moral principles for providing orientation in modern society might be, a serious omission has been made in that the problem of implementation is not addressed. Two fundamental question have neither been raised nor answered: (1) Why should self‐interested individuals follow the proposed moral principles in their daily conduct? (2) Are societal institutions of such a design that is in the power of the (...) individuals to follow these moral principles? It is shown in this article that an economic theory of morals does systematically address these two questions and therefore provides a firm basis for discussing the possibilities and boundaries of following the moral principles inherent in the long history of moral philosophy. (shrink)

This chapter addresses the distinction between private and public and the difference between ‘public’ and ‘official’. Drawing on a comparative analysis of Asian cities, it looks at the ways in which the local, the national and the global levels, which serve different, sometimes contrasting, interests, are negotiated and reconciled in the city. The chapter suggests that different forms of reconciliation have brought about an alternative ‘insitutionalisation’ of the public space. Such an institutionalisation is reflected in the access to, and dissemination (...) of, information—e.g., access to the media—and, above all, in the control over the common goods. The public sphere is used to voice discontent, leading to a new definition of the ‘common good’; that is, the inclusion, or non-exclusion, of large sections of the population which, though initially marginal, can become significant in shaping urban politics. (shrink)

Barsalou's theory of perceptual symbol systems is considered from a metacognitive perspective. Two examples are discussed in terms of the proposed perceptual symbol theory. First, recent results in research on feeling-of-knowing judgement are used to argue for a representation of familiarity with input cues. This representation should support implicit memory. Second, the ability of maintaining a theory of other people's beliefs (theory of mind) is considered and it is suggested that a purely simulation-based view is insufficient to explain the available (...) evidence. Both examples characterize areas where Barsalou's theory would benefit from additional detail. (shrink)

Bd. 1. Die Geschichte der Rechtsphilosophie und die allgemeinen Lehren.--Bd. 2. Das System des Privatrechts, die Staatslehre und die Prinzipien des Völkerrechts.

The existence of neural correlates of consciousness (NCC) is not enough for philosophical purposes. On the other hand, there's more to NCC than meets the sceptic's eye. (I) NCC are useful for a better understanding of conscious experience, for instance: (1) NCC are helpful to explain phenomenological features of consciousness – e.g., dreaming. (2) NCC can account for phenomenological opaque facts – e.g., the temporal structure of consciousness. (3) NCC reveal properties and functions of consciousness which cannot be elucidated either (...) by introspective phenomenology or by psychological experiments alone – e.g., vision. (II) There are crucial problems and shortcomings of NCC: (1) Correlation implies neither causation nor identity. (2) There are limitations of empirical access due to the problem of other minds and the problem of self-deception, and (3) due to the restrictions provided by inter- and intraindividual variations. (4) NCC cannot be catched by neuroscience alone because of the externalistic content of representations. Therefore, NCC are not sufficient for a naturalistic theory of mind, (5) nor are they necessary because of the possibility of multiple realization. (III) Nevertheless, NCC are relevant and important for the mind-body problem: (1) NCC reveal features that are necessary at least for behavioral manifestations of human consciousness. (2) But NCC are compatible with very different proposals for a solution of the mind-body problem. This seems to be both advantageous and detrimental. (3) NCC restrict nomological identity accounts. (4) The investigation of NCC can refute empirical arguments for interactionism as a case study of John Eccles' dualistic proposals will show. (5) The discoveries of NCC cannot establish a naturalistic theory of mind alone, for which, e.g., a principle of supervenience and a further condition – and therefore philosophical arguments – are required. (shrink)

The existence of quantum correlates of consciousness (QCC) is doubtful from a scientific perspective. But even if their existence were verified, philosophical problems would remain. On the other hand, there could be more to QCC than meets the sceptic's eye: • QCC might be useful or even necessary for a better understanding of conscious experience or quantum physics or both. The main reasons for this are: the measurement problem (the nature of observation, the mysterious collapse of the wave function, etc.), (...) ostensibly shared features of quantum phenomena and conscious phenomena (e.g., complementarity, nonspatiality, acausality, spontaneity, and holism) and connections (ontology, causation, and knowledge), the qualia problem (subjectivity, explanatory gap etc.). But there are many problems, especially questions regarding realism and the nature and role of conscious observers; • QCC are conceptually challenging, because there are definitory problems and some crucial ontological and epistemological shortcomings. It is instructive to compare them with recent proposals for understanding neural correlates of consciousness (NCC). QCC are not sufficient for a quantum theory of mind, nor might they be necessary except perhaps in a very broad sense; • QCC are also empirically challenging. Nevertheless, QCC could be relevant and important for the mindbody problem: QCC might reveal features that are necessary at least for behavioral manifestations of human consciousness. But QCC are compatible with very different proposals for a solution of the mind-body problem. This seems to be both advantageous and detrimental. QCC restrict accounts of nomological identity. The discovery of QCC cannot establish a naturalistic theory of mind alone. But there are also problems with QCC in the framework of other ontologies. (shrink)

Probabilistic reasoning is heavily investigated in decision research. Violations of probability theory have been demonstrated numerously, for instance, the tendency to overestimate the joint probab...

This study seeks to clarify the nature of linguistic synesthesia using a lexical-conceptual account. Based on a lexical analysis of Mandarin synesthetic usages, we find that linguistic synesthesia maps the metaphorical meaning between two domains; and linguistic synesthetic mappings and conceptual metaphoric mappings have similar behaviors when sense modalities are treated as conceptual domains that contain a set of mappings constrained by Mapping Principles. This lexical-conceptual account is designed to capture the fact that linguistic synesthesia involves mapping between lexicalized concepts (...) of sensory properties, instead of the real-time sensory input that is processed in neurological synesthesia. The incorporation of a lexical semantic view with the framework of Conceptual Metaphor Theory not only offers a coherent and comprehensive account for the nature of linguistic synesthesia, but also handles aspects of linguistic synesthesia previously only accounted for by non-metaphorical accounts. These design features make this proposal the most comprehensive account to fit the current data. Furthermore, by showing linguistic synesthesia as a type of metaphor, our study strengthens the role of conceptual metaphors as the link between the perceived world and our conceptualization of that world. (shrink)

This study proposes an operational approach to a metaphorical framing analysis using large-scale data. We conducted a case analysis of how war metaphors are framed to address various societal issues in a corpus of public speeches by Hong Kong government officials. By investigating patterns of lexical choices under the source domain of WAR and the underlying reasons for the source-target domain mappings (i.e. Mapping Principles), we found that the target domain of social issues in Hong Kong is primarily conceptualized in (...) terms of a combat frame, and governmental issues are primarily talked about in terms of a protection frame, both of which are positively evaluated. Additionally, economic issues are primarily addressed in terms of a strategy frame, which is both positively and negatively evaluated. We show that analyzing the Mapping Principles of these conceptual metaphors captures the “selection” process of framing at the dimensions of frame frequency and frame sentiment, allowing for a principled way to propose a metaphorical framing analysis in corpora-based studies. The proposed approach enriches Critical Discourse Analysis studies of metaphorical framing and bridges the link between metaphor analysis at a conceptual level and framing analysis at a communication level. (shrink)

Source domain verification has not received as much attention as criteria for metaphor identification in the study of conceptual metaphor. In this paper, we provide a replicable approach to source...

C-systems were defined by Cartmell as models of generalized algebraic theories. B-systems were defined by Voevodsky in his quest to formulate and prove an initiality conjecture for type theories. They play a crucial role in Voevodsky’s construction of a syntactic C-system from a term monad. In this work, we construct an equivalence between the category of C-systems and the category of B-systems, thus proving a conjecture by Voevodsky.

Aujourd’hui, le gouvernement fédéral entreprend de diriger les situation d’urgence, un tâche si intimidante qu’elle fait appel à la panoplie de réglementation et de pouvoirs économiques résidant dans les institutions et les bureaucraties fédérales. L’Administration Fédérale de Gestion des Situations d’Urgence occupe la pôle position dans cet effort massif. Mais une société qui autorise le gouvernement à répondre face aux catastrophes naturelles et autres calamités de ce type peut-elle espérer préserver sa liberté? Non. En fait, le gouvernement d’une société libre (...) peut gouverner efficacement sans détruire la liberté, si et seulement si ses citoyens en ont décidé ainsi.Today, the federal government undertakes to manage emergencies, a task so daunting that it must call forth all of the concentrated regulatory and economic power that resides in federal institutions and bureaucracies. The Federal Emergency Management Administration takes the point position in this massive effort. But can a society which authorizes government to respond to natural disasters and other such calamities hope to preserve its liberty? No. In fact, the government of a free society can govern effectively without destroying freedom, if and only if the citizens are willing to be so governed. (shrink)

Aujourd’hui, le gouvernement fédéral entreprend de diriger les situation d’urgence, un tâche si intimidante qu’elle fait appel à la panoplie de réglementation et de pouvoirs économiques résidant dans les institutions et les bureaucraties fédérales. L’Administration Fédérale de Gestion des Situations d’Urgence occupe la pôle position dans cet effort massif. Mais une société qui autorise le gouvernement à répondre face aux catastrophes naturelles et autres calamités de ce type peut-elle espérer préserver sa liberté? Non. En fait, le gouvernement d’une société libre (...) peut gouverner efficacement sans détruire la liberté, si et seulement si ses citoyens en ont décidé ainsi.Today, the federal government undertakes to manage emergencies, a task so daunting that it must call forth all of the concentrated regulatory and economic power that resides in federal institutions and bureaucracies. The Federal Emergency Management Administration takes the point position in this massive effort. But can a society which authorizes government to respond to natural disasters and other such calamities hope to preserve its liberty? No. In fact, the government of a free society can govern effectively without destroying freedom, if and only if the citizens are willing to be so governed. (shrink)

Name der Zeitschrift: Frühmittelalterliche Studien Jahrgang: 36 Heft: 2 Seiten: 403-415.

Zusammenfassung Die zunehmende Verbreitung und Weiterentwicklung sogenannter künstlicher Intelligenz hat neue Fragen der Zurechenbarkeit und Verantwortung erzeugt. In diesem Zusammenhang ist der Vorschlag gemacht worden, das neue Rechtsinstrument der ‚elektronischen Person‘ zu schaffen. Damit sind grundlegende Fragen des menschlichen Selbstverständnisses berührt, es verbinden sich aber auch viele Missverständnisse mit jenem Vorschlag, sowohl bei denen, die den Vorschlag befürworten, als auch aufseiten derer, die ihn kritisch sehen. Dieser Beitrag untersucht die Problematik aus juristischer und ethisch-theologischer Perspektive und gelangt zu einer abwägenden (...) Einschätzung bezüglich der Möglichkeiten und Grenzen der elektronischen Person. (shrink)

Present-day Science-Fiction films repeatedly describe an obliteration of boundaries between human and other beings, and technical artefacts, which includes a threat to the human species. This motif relates to an anthropological fear of transformation of the human species due to advances in technology. This fear does not primarily refer to an invasion by extraterrestrial enemies, but to the anthropotechnization of man.