Neuropsychological patients exhibiting category-selective visual agnosias provide unique insights into the cognitive functions of the human brain. Transcranial magnetic stimulation, in contrast, can be used to draw causal inferences, as one of the effects of the cortical disruption induced by magnetic stimulation is to act as a “virtual lesion” lasting from tens of milliseconds up to approximately one hour, depending on the type of stimulation. This specificity offers a unique advantage in psychological testing as TMS can be used to test (...) where and when cognitive computations are performed. This article briefly describes TMS, considers the small but growing number of studies that use TMS to disrupt face processing. It discusses how TMS can be used in the future to understand better how faces are cortically represented in the human brain. (shrink)

In The Priority of the Person, world-class philosopher David Walsh advances the argument set forth in his highly original philosophic meditation Politics of the Person as the Politics of Being (2015), that "person" is the central category of modern political thought and philosophy. This book is divided into three main parts. Beginning with the political discovery of the inexhaustibility of persons, it then explores the philosophic differentiation of the idea of the "person," and finally traces its historical emergence (...) through art, science, and faith. Walsh argues that, although the roots of the idea of "person" are found in the Greek concept of the mind and in the Christian conception of the soul, this notion is ultimately a distinctly modern achievement, because it is only the modern turn toward interiority that illuminated the unique nature of persons as each being a world unto him or herself. As Walsh shows, it is precisely this feature of persons that makes it possible for us to know and communicate with others, for we can only give and receive one another as persons. In this way alone can we became friends and, in friendship, build community. In showing how the person is modernity's central preoccupation, and in demonstrating how it is only as persons that we can truly give ourselves to others and thus develop real community, David Walsh's The Priority of the Person makes an important contribution to current discussions in both political theory and philosophy. It will also appeal to students and scholars of theology and literature, and any groups interested in the person and personalism. (shrink)

A personalist account of persons -- Persons as beyond good and evil -- Reality transcends itself in persons -- God as the seal of the personal -- Art as the radiance of persons in reality -- History as the memory of persons -- Politics of the person.

From Locke to Kierkegaard to those annoying car ads that promise “No Boundaries”— Is our use of the word 'freedom' still coherent? Was it ever coherent? Is it significant that this fuzzy term is so often used to carry so much rhetorical force? With Larry Hatab , David Walsh , and Mark Murphy.

From Locke to Kierkegaard to those annoying car ads that promise “No Boundaries”— Is our use of the word 'freedom' still coherent? Was it ever coherent? Is it significant that this fuzzy term is so often used to carry so much rhetorical force? With Larry Hatab, David Walsh, and Mark Murphy.

Horizontal transfer (HT) is the transmission of genetic material between non‐mating species, a phenomenon thought to occur rarely in multicellular eukaryotes. However, many transposable elements (TEs) are not only capable of HT, but have frequently jumped between widely divergent species. Here we review and integrate reported cases of HT in retrotransposons of the BovB family, and DNA transposons, over a broad range of animals spanning all continents. Our conclusions challenge the paradigm that HT in vertebrates is restricted to infective long (...) terminal repeat (LTR) retrotransposons or retroviruses. This raises the possibility that other non‐LTR retrotransposons, such as L1 or CR1 elements, believed to be only vertically transmitted, can horizontally transfer between species. Growing evidence indicates that the process of HT is much more general across different TEs and species than previously believed, and that it likely shapes eukaryotic genomes and catalyses genome evolution. (shrink)

The Modern Philosophical Revolution breaks new ground by demonstrating the continuity of European philosophy from Kant to Derrida. Much of the literature on European philosophy has emphasised the breaks that have occurred in the course of two centuries of thinking. But as David Walsh argues, such a reading overlooks the extent to which Kant, Hegel, and Schelling were already engaged in the turn toward existence as the only viable mode of philosophising. Where many similar studies summarise individual thinkers, (...) this book provides a framework for understanding the relationships between them. Walsh thus dispels much of the confusion that assails readers when they are only exposed to the bewildering range of positions taken by the philosophers he examines. His book serves as an indispensable guide to a philosophical tradition that continues to have resonance in the post-modern world. (shrink)

Looks at the contemporary problems of alienation and separation, and discusses the attempts of various Jewish groups to learn from the mistakes and accomplishments of modernism.

In The Growth of the Liberal Soul, David Walsh confronts a core difficulty of the liberal democratic tradition in explaining and justifying itself.

Clearly we have entered an era of heightened interest in spirituality. The proliferation of books, music, and paraphernalia espousing the way of the spirit is a striking phenomenon. Everywhere there is a new willingness to admit that the categories of rational thought, the authority of science, are no longer adequate to the task of making sense of our lives. A search for meaning has become pervasive. Equally striking has been the rise of experiential religion. Evangelical and fundamentalist churches are the (...) fastest growing denominations worldwide. This is no accident, for they respond exactly to the failure of the modern forms of life. The modern ethos, for all its technological prowess, is experienced as an abyss of misery and confusion. The only way out is to leap over the entire modern perspective to locate oneself within the security of a divinely revealed faith. The difficulty, according to author David Walsh, is that neither the new age religions nor the old-time religions have enabled us to leap out of the modern world. The discovery of a source of meaning beyond that world does not automatically clarify all meaning within it. Finding a way to link the modern rational order and a spirituality pointing beyond it is what this book is about. Guarded By Mystery is a contemporary meditation on a problem that has been at the core of the human condition. It is intended for all who have been perplexed by the disconnection between the two worlds in which they live. Walsh explains how their experience of spiritual openness is meaningful within the modern world. He shows how that world is itself dependent on the same sources of spiritual illumination they have discovered within themselves. David Walsh is professor of politics at The Catholic University of America. He is the author of numerous works including, After Ideology: Recovering the Spiritual Foundations of Freedom, The Growth of the Liberal Soul, and The Third Millennium. " Walsh] writes about the spiritual quest in a time dubbed 'postmodern, ' meaning that the older rational securities have been shattered. Walsh ranges widely--from literary criticism to politics and art--in lifting up the luminous hints of the transcendent in the everyday. A most thoughtful reflection that should have a broad appeal."--First Things "At the beginning of a new century and new millennium, we can be grateful for such a wise and experienced guide as David Walsh as we explore the promise and pitfalls in our historical moment. Of most particular note is his intelligently hopeful understanding of the liberal democratic tradition and the ways in which modernity, after a century of catastrophically wrong turns, may now be fulfilling its aspiration toward transcendence. As he convincingly argues, the mystery to which contemporary thought is increasing open is not a threat but our surest guard."--Rev. Richard John Neuhaus, editor in chief, First Things "An engrossing read... a superb tract for the times that is just made to order.... Walsh's book is an apologia for the reality of God and for God's grounding of human existence on both the personal and socio-political levels in a postmodern time."--Prof. William M. Thompson, Duquesne University "Written for a general audience, yet informed by the wisdom of the ages and enlivened by an elegant gift of language, David Walsh's searching meditation on the heights and depths of human existence is a philosopher's illumination of reality of rare beauty and power. It ranges from politics to faith to the arts to find glimmers of hope and unsuspected sources of succor for a time out of joint. It celebrates the individual human person, as imago Dei, the abiding glory of creation. And it explores liberty, the prize of personality and of political order alike, through which we are uniquely drawn to meaningful partic. (shrink)

In _The Later Middle Ages,_ the third volume of his monumental _History of Political Ideas,_ Eric Voegelin continues his exploration of one of the most crucial periods in the history of political thought. Illuminating the great figures of the high Middle Ages, Voegelin traces the historical momentum of our modern world in the core evocative symbols that constituted medieval civilization. These symbols revolved around the enduring aspiration for the _sacrum imperium,_ the one order capable of embracing the transcendent and immanent, (...) the ecclesiastical and political, the divine and human. The story of the later Middle Ages is that of the "civilizational schism"—the movement in which not only the reality but the aspiration for the _sacrum imperium_ gradually disappeared and the unification of faith and reason dissolved. His recognition of this civilizational schism provides Voegelin with a unique perspective on medieval society. William of Ockham, Dante, Giles of Rome, and Marsilius of Padua all emerge in Voegelin's study as predecessors to modern thought; each turns to personal authority and intellectual analysis in an attempt to comprehend the loss of the _sacrum imperium_ as an authoritative ideal. Voegelin is further drawn into investigations that, despite insufficient attention by scholars, still bear relevance to the study of the later Middle Ages. The mysticism apparent in _Piers Plowman_ and the apocalyptic revolt of Cola di Rienzo are merely two reactions to the disintegration of wholeness. Yet the story of the later Middle Ages does not merely revolve around disintegration. Voegelin recognizes the emergence of the constitutional political tradition as the most positive development of this period. He is at his best when explaining the difference between the presence of a representative institution and the growth of communal consciousness. Voegelin's study of the English political pattern is matched only by his unique perspective on the German imperial zone, culminating in a fitting conclusion on Nicholas of Cusa—the one political thinker with the ability to evoke the unity of mankind beyond fragmentation. _The Later Middle Ages_ is at once a brilliant examination of the symbols that characterized medieval society and a remarkable predecessor to Voegelin's study of the modern world, beginning with the Renaissance and the Reformation. (shrink)

Volume 6 of _The Collected Works of Eric Voegelin_ offers the first translation of the full German text of _Anamnesis_ published in 1966. The previous English edition, translated by Gerhart Niemeyer, focused largely on the sections of _Anamnesis_ dealing directly with Voegelin's philosophy of consciousness. It omitted some of the extensive historical studies on which the philosophy of consciousness was based. To properly understand Voegelin's work, however, it is essential to give equal weight to the empirical as well as the (...) philosophical aspects. This complete version of _Anamnesis_ captures the full integrity of his vision. It is at once scientific, in the sense of fidelity to the demands of historiographic scholarship, and philosophical, in exploring the significance of the texts for the meaning of human existence in society and history. _Anamnesis_ is a pivotal work within Voegelin's intellectual odyssey. Alone among Voegelin's books, it reveals an author looking back and taking stock of his growth rather than customarily forging ahead into new regions and new problems. This critical work is both a recollection of Voegelin's own development, reaching back even to his infant memories, and a demonstration of the anamnetic method as applied to a wide range of historically remembered materials. Written as more than just a collection of essays, _Anamnesis_ is the volume in which Voegelin works out for himself the reconceptualization of what _Order and History,_ and by definition his central philosophical approach, is going to be. By revisiting his previous work—a departure from Voegelin's usual scholarly habits—he found at last the literary form for the kind of empirical philosophical meditation that had long absorbed his labors. Parts I and III contain biographical and meditative reflections written by Voegelin in 1943 and 1965, respectively. The first part details the breakthrough by which Voegelin recovered consciousness from the current theories of consciousness. Part III begins as a rethinking of the Aristotelian exegesis of consciousness, and then expands into new areas of awareness that had not come within the knowledge of classic philosophy. Between these two meditative selections are eight studies that demonstrate how the historical phenomena of order gave rise to the type of analysis which culminates in the meditative exploration of consciousness. (shrink)

Irrelevant emotional stimuli often capture attention, disrupting ongoing cognitive processes. In two experiments, we examined whether availability of rewards can prevent...

This book explores Dostoevsky as a political thinker from his religious and philosophical foundation to nineteenth-century European politics and how themes that he had examined are still relevant for us today.

Volume 6 of The Collected Works of Eric Voegelin offers the first translation of the full German text of Anamnesis published in 1966.

The ability to sequence individual genomes is leading to the identification of an increasing number of genetic risk factors for serious diseases. Knowledge of these risk factors can often provide significant medical and psychological benefit, but also raises complex ethical and social issues. This paper focuses on one area of rapid progress: the identification of mutations causing long QT syndrome and other cardiac channel disorders, which can explain some previously unexplained deaths in infants (SIDS) and children and adults (SUDS) and (...) prevent others from occurring. This genetic knowledge, discovered posthumously in many cases, has implications for clinical care for surviving family members who might carry the same mutations. The information obtained from genetic testing, in the context of personal and family history, can guide individually tailored interventions that reduce risk and save lives. At the same time, obtaining and disclosing genetic information raises difficult issues about confidentiality and decision making within families. We draw on the experience of the Montefiore-Einstein Center for Cardiogenetics, which has played a leading role in the genetic diagnosis and clinical management of cardiac channel diseases, to explore some of the challenging ethical questions arising in affected families with adolescent children. We focus on the related issues of (1) family confidentiality, privacy and disclosure and (2) adolescent decision making about genetic risk, and argue for the value of interdisciplinary dialogue with affected families in resolving these issues. (shrink)

The value of what Magee has done can best be appreciated by recalling the number of times that scholars of Hegel have pointed toward the relationship with the esoteric and mystical sources in which he had been immersed. The romantic and idealist circle at Jena seemed at times consumed with an unquenchable thirst for the Gnostic, Hermetic, theosophical, and speculative mysticism that they felt resonated with their own project. Moreover, the connection between the philosophical and the mystical does not have (...) to be discerned through some secret reading of their texts. It is openly acknowledged, and they make no secret of their admiration. Both Schelling and Hegel extensively reference Jacob Boehme, a pivotal link within this mystico-speculative tradition. Hegel singles him out in the Lectures on the History of Philosophy as the great speculative source of the modern world, comparable in significance to the Baconian empiricist foundation of natural science. With Magee’s study in hand, scholars need no longer shy away from this acknowledged connection and can certainly no longer employ the excuse of its obscurity to resist closer examination. (shrink)

Few categories are as useful for illuminating the whole complex of correlative intellectual, spiritual and political problems of the modern world as the opposites of time and eternity. Tom Darby has made impressive use of the dialectic of time and its overcoming in the “eternal instant” not only to analyse the central preoccupations of Rousseau, Hegel and others, but also to reveal their representative significance within the peculiarly modern concern with existence. One is reminded of the Homeric distinction between men (...) and gods as that of mortals versus immortals, which was replaced by the Platonic redefinition of man as the mortal immortal who lives in the tension between life and death. For it is precisely the rejection of that tension that has formed the self-understanding of Western man since the Renaissance and has so completely absorbed the interest of the thinkers covered by Darby’s study. The search for perfection in individual and political existence is in essence the desire to escape the temporality of the human condition. Imperfection, finiteness, contingency and death are the inescapable fate of all creatures that live within time. It is only by escaping temporality that we can aspire to the being of eternity which, in Boethius’s formulation, is “the simultaneously whole and perfect possession of interminable life”. (shrink)

Few categories are as useful for illuminating the whole complex of correlative intellectual, spiritual and political problems of the modern world as the opposites of time and eternity. Tom Darby has made impressive use of the dialectic of time and its overcoming in the “eternal instant” not only to analyse the central preoccupations of Rousseau, Hegel and others, but also to reveal their representative significance within the peculiarly modern concern with existence. One is reminded of the Homeric distinction between men (...) and gods as that of mortals versus immortals, which was replaced by the Platonic redefinition of man as the mortal immortal who lives in the tension between life and death. For it is precisely the rejection of that tension that has formed the self-understanding of Western man since the Renaissance and has so completely absorbed the interest of the thinkers covered by Darby’s study. The search for perfection in individual and political existence is in essence the desire to escape the temporality of the human condition. Imperfection, finiteness, contingency and death are the inescapable fate of all creatures that live within time. It is only by escaping temporality that we can aspire to the being of eternity which, in Boethius’s formulation, is “the simultaneously whole and perfect possession of interminable life”. (shrink)

The essays in this volume all deal in one way or another with Hegel’s distinction between the state and civil society. It is a particularly appropriate choice of theme since, as Pelczynski remarks in the Introduction, “the conceptual separation of the state and civil society is one of the most original features of Hegel’s political and social philosophy although a highly problematic one”. Indeed it might well be argued that it is the key to his entire conception of the modern (...) state and it is certainly the point of bifurcation from which emerge the two dominant political forms of the modern world, Marxism and liberal democracy. The former regards the state as a mere reflection of the dominant economic relationships of civil society, eventually to be superseded through the resolution of the contradictions of civil society itself; the latter identifies the state with the institutional structures of civil society, as an expression of the individualist contractarian foundation of all political association. Hegel stands alone in arguing for the ethical community of the state as the controlling order for individual self-interest. Clearly it is this aspect that is of greatest appeal to the contributors of this collection. (shrink)

Summary A total of 1068 secondary school pupils completed a questionnaire concerned with enjoyment of school, enjoyment of subjects and what they attributed academic success to. Gender differences were shown in the overall enjoyment of school (girls expressing greater enjoyment). Girls also reported liking friends, teachers, outings and lessons more than boys, while boys reported liking sports and school clubs more. Enjoyment of school subjects reflected traditional sex stereotyping: girls reported more liking than did boys for English, French, German, history, (...) drama, music and home economics while boys reported more liking for science. craft and design technology, physical education and information technology. Some gender differences were shown in rating factors contributing to academic success (girls rating hard work and teachers? liking for you as more important than boys, and boys rating cleverness, talent and luck as more important than girls) but attributions with respect to academic success varied more with age than with gender. (shrink)

Titles and abstracts for the Pitt-London Workshop in the Philosophy of Biology and Neuroscience: September 2001.

Rationale Treatment guidelines recommend a more conservative surgical approach than mastectomy for early stage breast cancer and a stronger emphasis on adjuvant therapy. Registry data at South Australian teaching hospitals have been used to monitor survivals and treatment in relation to these guidelines.Aims and objectives To use registry data to: (1) investigate trends in survival and treatment; and (2) compare treatment with guidelines.Methods Registry data from three teaching hospitals were used to analyse trends in primary courses of treatment of breast (...) cancers during 1977–2003 (n = 4671), using univariate analyses and multiple logistic regression. Disease-specific survivals were analysed using Kaplan–Meier product limit estimates and multivariable Cox proportional hazards regression.Results The 5-year survival was 79.9%, but with a secular increase, reaching 83.6% in 1997–2003. The relative risk of death (95% confidence limits) was 0.74 (0.62, 0.88) for 1997–2003, compared with previous diagnoses, after adjusting for tumour node metastasis stage, grade, age and place of residence. Treatment changes included an increase in conservative surgery (as opposed to mastectomy) from 51.7% in 1977–1990 to 76.8% in 1997–2003 for stage I (P < 0.001) and from 31.1% to 52.2% across these periods for stage II (P < 0.001). Adjuvant radiotherapy also became more common (P < 0.001), with 20.6% of patients receiving this treatment in 1977–1990 compared with 60.7% in 1997–2003. Radiotherapy generally was more prevalent when conservative surgery was provided, although also relatively common in mastectomy patients when tumour diameters exceeded 50 mm or when there were four or more involved nodes. The proportion of patients receiving chemotherapy increased (P < 0.001), from 19.6% in 1977–1990 to 36.9% in 1997–2003, and the proportion having hormone therapy also increased (P < 0.001), from 34.3% to 59.4% between these periods.Conclusions Survivals appear to be increasing and treatment trends are broadly consistent with guideline directions, and the earlier research on which these recommendations were based. (shrink)

Reaching into our own time, _Crisis and the Apocalypse of Man_ confronts the disintegration of traditional sources of meaning and the correlative attempt to generate new sources of order from within the self. Voegelin allows us to contemplate the crisis in its starkest terms as the apocalypse of man that now seeks to replace the apocalypse of God. The totalitarian upheaval that convulsed Voegelin's world, and whose aftermath still defines ours, is only the external manifestation of an inner spiritual turmoil. (...) Its roots have been probed throughout the eight volumes of _History of Political Ideas,_ but its emergence is marked by the age of Enlightenment. In our postmodern era, discussions of the collapse of the "enlightenment project" have become commonplace. Voegelin compels us to follow the great-souled individuals who sought to go from disintegration of the present toward evocations of order for the future. Such thinkers as Comte, Bakunin, and Marx suffered through the crisis and fully understood the need for a new outpouring of the spirit. They resolved to supply the deficiency themselves. As a consequence they launched us irrevocably on the path of the apocalypse of man. One of the great merits of Voegelin's analysis is his exposition of the pervasive character of this crisis. It is not confined to the megalomaniacal dreamers of a revolutionary apocalypse; rather, echoes of it are found in the more moderate Enlightenment preoccupation with progress to be attained through application of the scientific method. Faith in the capacity of instrumental reason to answer the ultimate questions of human existence defined men such as Voltaire, Helvétius, Diderot, D'Alembert, and Condorcet. It remains the authoritative faith of our world today, Voegelin argues, demonstrated by our continuing inability to step outside the parameters of the Enlightenment. Are we condemned, then, to oscillate between the rational incoherence of a science that never delivers on its promises and a now discredited revolutionary idealism that wreaks havoc in practice? This is the question toward which Voegelin's final volume points. While not direct, his response is evident everywhere. _Crisis and the Apocalypse of Man_ could have been written only by a man who had reached his own resolution of the crisis. (shrink)