Wybo Houkes - A Parting of the Ways: Carnap, Cassirer, and Heidegger - Journal of the History of Philosophy 40:4 Journal of the History of Philosophy 40.4 554-555 Book Review A Parting of the Ways: Carnap, Cassirer, and Heidegger Michael Friedman. A Parting of the Ways: Carnap, Cassirer, and Heidegger. Chicago: Open Court, 2000. Pp. xv + 175. Paper, $24.95. For present-day philosophers, the division between "analytic" and "continental" philosophy is a fact of life. In this elegant little (...) book, Michael Friedman studies its origins. In earlier essays, collected in his Reconsidering Logical Positivism , Friedman argued that Carnap and other logical empiricists are best understood as adapting their Neokantian heritage to, among other things, the rapid developments in logic and physics. In A Parting of the Ways, Friedman broadens.. (shrink)

In this paper we present an action-theoretic account of artefact using and designing and describe our ICE-theory of function ascriptions to technical artefacts. By means of this account and theory we analyse the thesis of the dual nature of technical artefacts according to which descriptions of technical artefacts draw on structural and intentional conceptualisations. We show that the ascription of technical functions to technical artefacts can connect the intentional and structural parts of descriptions of artefacts, but also separate these parts. (...) Our conclusion is that the concept of technical functions forms a ‘conceptual drawbridge’ between the intentional and structural natures of technical artefacts.Keywords: Intentional and structural descriptions; Technical artefacts; Function theory; Action theory; Use; Design. (shrink)

The aim of this paper is to evaluate etiological accounts of functions for the domain of technical artefacts. Etiological theories ascribe functions to items on the basis of the causal histories of those items; they apply relatively straightforwardly to the biological domain, in which neo-Darwinian evolutionary theory provides a well-developed and generally accepted background for describing the causal histories of biological items. Yet there is no well-developed and generally accepted theory for describing the causal history of artefacts, so the application (...) of etiological theories to the technical domain is hardly straightforward. In this paper we consider the transposition of etiological theories in general from the biological to the technical domain. We argue that a number of etiological theories that appear defensible for biology become untenable for technology. We illustrate our argument by showing that the standard etiological accounts of Neander and Millikan, and some recent attempts to improve on them, provide examples of such untenable theories. 1 Introduction 2 Desiderata for theories of functions 3 Etiological theories in general 3.1 Common core and divergent aims 3.2 Reproduction versus non-reproduction etiological theories 3.3 Intentionalist versus non-intentionalist etiological theories 4 Problems for etiological theories in the technical domain 5 The failure of existing reproduction theories 6 The failure of existing non-reproduction theories 7 Improving reproduction by hybridisation 8 Conclusions. (shrink)

The philosophy of artifacts is as marginal as it is one-sided. The majority of contributions to it are asides in works devoted to other subjects and focus on one characteristic feature: that artifacts are objects with functions. Indeed many artifacts, such as screwdrivers and toasters, come in functional kinds. Perhaps for this reason, philosophers elevated functions to the essences of artifacts or have developed general theories of function to describe artifacts along with their main subject: biological items. Most such theories (...) present one monolithic notion of function that applies to both. Dissident voices claim autonomy for artifact functions, or at least a small measure of conceptual independence, but it is seldom questioned that a theory of artifacts consists merely of a theory of artifact functions. (shrink)

The aim of this paper is to evaluate etiological accounts of functions for the domain of technical artefacts. Etiological theories ascribe functions to items on the basis of the causal histories of those items; they apply relatively straightforwardly to the biological domain, in which neo‐Darwinian evolutionary theory provides a well‐developed and generally accepted background for describing the causal histories of biological items. Yet there is no well‐developed and generally accepted theory for describing the causal history of artefacts, so the application (...) of etiological theories to the technical domain is hardly straightforward. In this paper we consider the transposition of etiological theories in general from the biological to the technical domain. We argue that a number of etiological theories that appear defensible for biology become untenable for technology. We illustrate our argument by showing that the standard etiological accounts of Neander and Millikan, and some recent attempts to improve on them, provide examples of such untenable theories.1Introduction2Desiderata for theories of functions3Etiological theories in general3.1Common core and divergent aims3.2Reproduction versus non‐reproduction etiological theories3.3Intentionalist versus non‐intentionalist etiological theories4Problems for etiological theories in the technical domain5The failure of existing reproduction theories6The failure of existing non‐reproduction theories7Improving reproduction by hybridisation8Conclusions. (shrink)

I argue that technological functions warrant specific epistemological attention, which they have not received thus far. From a user’s perspective, knowledge about the possible functions of an artefact is not provided exclusively by beliefs about its physical characteristics; it is primarily provided by know-how related to its use. Analysing the latter shows that standards of practical and not just theoretical reasoning are involved. Moreover, knowledge of the function of artefacts is primarily based on testimony and a social division of labour (...) with respect to rational artefact use. Combining these two features, knowledge of functions can be shown to create a rich normative context, manifest in notions such as ‘improper’ use: designers inform users about how they ought to use artefacts. This normativity in knowledge of functions, which takes a different shape for possible and proper functions, is lacking in standard, descriptive knowledge.Keywords: Epistemology; Function; Knowing-how; Testimony; Artefact; Practical rationality. (shrink)

We examine to what extent an adequate ontology of technical artefacts can be based on existing general accounts of the relation between higher-order objects and their material basis. We consider two of these accounts: supervenience and constitution. We take as our starting point the thesis that artefacts have a ‘dual nature’, that is, that they are both material bodies and functional objects. We present two criteria for an adequate ontology of artefacts, ‘Underdetermination’ and ‘Realizability Constraints’ , which address aspects of (...) the dual nature thesis. Assessing supervenience accounts, we find them either wanting with respect to these criteria or insufficiently informative. Next, we argue that a recent application of Lynne Rudder Baker’s constitution view to artefacts cannot meet our criteria, although the broader view leaves room for improvement. Based on our evaluation of the most promising candidates, we conclude that so far general metaphysical views fail to address the most salient features of artefacts. Although they can account for the fact that artefacts have a ‘dual nature’, they do not offer the conceptual resources needed to describe the relation between these natures; this relation raises a hard problem in metaphysics.Keywords: Metaphysics; Artefact; Supervenience; Constitution; Underdetermination. (shrink)

Michael Weisberg has argued that robustness analysis is useful in evaluating both scientific models and their implications and that robustness analysis comes in three types that share their form and aim. We argue for three cautionary claims regarding Weisberg's reconstruction: robustness analysis may be of limited or no value in evaluating models and their implications; the unificatory reconstruction conceals that the three types of robustness differ in form and role; there is no confluence of types of robustness. We illustrate our (...) central first claim with a case study: the application of Lotka-Volterra models to technology diffusion. (shrink)

The human enhancement debate typically centres on moral issues regarding changes in human nature, not on the means for these changes. We argue that one cannot grasp what is morally salient about human enhancement without understanding how technologies affect human action and practical reasoning. We present a minimalist conception of human agents as bounded practical reasoners. Then, we categorise different effects of technologies on our possibilities for action and our evaluation of these possibilities. For each, we discuss whether enhancement technologies (...) have morally salient effects; which technologies show these effects; and whether these differ significantly from those of other, non-enhancement technologies. We conclude that enhancement technologies are morally salient in several respects, that not all enhancement technologies share all those morally salient respects, and that continuities with traditional technologies may be found in all morally salient respects. (shrink)

In this paper we examine the possibilities of combining two central intuitions about artefacts: that they are functional objects, and that they are non-natural objects. We do so in four steps. First we argue that, contrary to common opinion, functions cannot be the cornerstone of a characterisation of artefacts. Our argument suggests an alternative view, which characterises artefacts as objects embedded in what we call use plans. Second, we show that this plan-centred successor of the function-focused view is at odds (...) with the non-naturalness intuition. Third, we show that this intuition can be developed by defining artefacts as produced or human-made objects, but that the resulting definition might collapse into the plan-centred view, and has trouble distinguishing artefact types or kinds. Finally, we propose a division of labour between production and use plans: among objects in general, artefacts are distinguished as human-made objects; within the domain of artefacts, types or kinds are characterised by the use plans in which artefacts are embedded. (shrink)

The notion of template has recently been discussed in relation to cross-disciplinary transfer of modeling efforts and in relation to the representational content of models. We further develop and disambiguate the notion of template and find that, suitably developed, it is useful in distinguishing and analyzing different types of transfer, none of which supports a non-representationalist view of models. We illustrate our main findings with the modeling of technology substitution with Lotka-Volterra Competition equations.

About three decades ago, the late Ronald Giere introduced a new framework for teaching scientific reasoning to science students. Giere’s framework presents a model-based alternative to the traditional statement approach—in which scientific inferences are reconstructed as explicit arguments, composed of (single-sentence) premises and a conclusion. Subsequent research in science education has shown that model-based approaches are particularly effective in teaching science students how to understand and evaluate scientific reasoning. One limitation of Giere’s framework, however, is that it covers only one (...) type of scientific reasoning, namely the reasoning deployed in hypothesis-driven research practices. In this paper, we describe an extension of the framework. More specifically, we develop an additional model-based scheme that captures reasoning in application-oriented practices (which are very well represented in contemporary science). Our own teaching experience suggests that this extended framework is able to engage a wider audience than Giere’s original. With an eye on going beyond such anecdotal evidence, we invite our readers to test out the framework in their own teaching. (shrink)

This paper systematically compares two frameworks for analysing technical artefacts: the Dual-Nature approach, exemplified by the contributions to Kroes and Meijers , and the collectivist approach advocated by Schyfter , following Kusch . After describing the main tenets of both approaches, we show that there is significant overlap between them: both frameworks analyse the most typical cases of artefact use, albeit in different terms, but to largely the same extent. Then, we describe several kinds of cases for which the frameworks (...) yield different analyses. For these cases, which include one-of-a-kind artefacts and defect types, the Dual-Nature framework leads to a more attractive analysis. Our comparison also gives us the opportunity to respond to Vaesen’s critical paper. We do so by distinguishing two readings of the Dual-Nature framework and pointing out that on the sustainable, weaker reading, Vaesen’s considerations supplement the framework rather than offering an alternative to it.Keywords: Technical artefact; Dual Nature framework; Collectivist framework; Artefact use. (shrink)

In this paper we use our work in the philosophy of technology to formulate a pluralist view on artefact categories and categorisation principles, as studied in cognitive science. We argue, on the basis of classifications derived by philosophical reconstruction, that artefacts can be clustered in more than one way, and that each clustering may be taken as defining psychological artefact categories. We contrast this pluralism with essentialism and super-minimalism on artefact categories and we argue that pluralism is coherent with experimental (...) results regarding the context-dependence of artefact categorisation. (shrink)

In this paper we examine the possibilities of combining two central intuitions about artefacts: that they are functional objects, and that they are non-natural objects. We do so in four steps. First we argue that, contrary to common opinion, functions cannot be the cornerstone of a characterisation of artefacts. Our argument suggests an alternative view, which characterises artefacts as objects embedded in what we call use plans. Second, we show that this plan-centred successor of the function-focused view is at odds (...) with the non-naturalness intuition. Third, we show that this intuition can be developed by defining artefacts as produced or human-made objects, but that the resulting definition might collapse into the plan-centred view, and has trouble distinguishing artefact types or kinds. Finally, we propose a division of labour between production and use plans: among objects in general, artefacts are distinguished as human-made objects; within the domain of artefacts, types or kinds are characterised by the use plans in which artefacts are embedded. (shrink)

Scientific disagreements sometimes persist even if scientists fully share results of their research. In this paper we develop an agent-based model to study the impact of diverging diagnostic values scientists may assign to the evidence, given their different background assumptions, on the emergence of polarization in the scientific community. Scientists are represented as Bayesian updaters for whom the diagnosticity of evidence is given by the Bayes factor. Our results suggest that an initial disagreement on the diagnostic value of evidence can, (...) but does not necessarily, lead to polarization, depending on the sample size of the performed studies and the confidence interval within which scientists share their opinions. In particular, the more data scientists share,the more likely it is that the community will end up polarized. (shrink)

Evolutionary anthropologists and archaeologists have been considerably successful in modelling the cumulative evolution of culture, of technological skills and knowledge in particular. Recently, one of these models has been introduced in the philosophy of science by De Cruz and De Smedt (Philos Stud 157:411–429, 2012), in an attempt to demonstrate that scientists may collectively come to hold more truth-approximating beliefs, despite the cognitive biases which they individually are known to be subject to. Here we identify a major shortcoming in that (...) attempt: De Cruz & De Smedt’s mathematical model makes one particularly strong tractability assumption that causes the model to largely miss its target (namely, truth accumulation in science), and that moreover conflicts with empirical observations. The second, more constructive part of the paper presents an alternative, agent-based model, which allows one to much better examine the conditions for scientific progress and decline. (shrink)

The consensus among cultural evolutionists seems to be that human cultural evolution is cumulative, which is commonly understood in the specific sense that cultural traits, especially technological traits, increase in complexity over generations. Here we argue that there is insufficient credible evidence in favor of or against this technological complexity thesis. For one thing, the few datasets that are available hardly constitute a representative sample. For another, they substantiate very specific, and usually different versions of the complexity thesis or, even (...) worse, do not point to complexity increases. We highlight the problems our findings raise for current work in cultural-evolutionary theory, and present various suggestions for future research. (shrink)

A deflationary perspective on theories of cultural evolution, in particular dual-inheritance theory, has recently been proposed by Lewens. On this ‘pop-culture’ analysis, dual-inheritance theorists apply population thinking to cultural phenomena, without claiming that cultural items evolve by natural selection. This paper argues against this pop-culture analysis of dual-inheritance theory. First, it focuses on recent dual-inheritance models of specific patterns of cultural change. These models exemplify population thinking without a commitment to natural selection of cultural items. There are grounds, however, for (...) doubting the added explanatory value of the models in their disciplinary context—and thus grounds for engaging in other potentially explanatory projects based on dual-inheritance theory. One such project is suggested by advocates of the theory. Some of the motivational narratives that they offer can be interpreted as setting up an adaptationist project with regard to cumulative change in cultural items. We develop this interpretation here. On it, dual-inheritance theory features two interrelated selection processes, one on the level of genetically inherited learning mechanisms, another on the level of the cultural items transmitted through these mechanisms. This interpretation identifies a need for further modelling efforts, but also offers scope for enhancing the explanatory power of dual-inheritance theory. (shrink)

In this paper we examine the possibilities of combining two central intuitions about artefacts: that they are functional objects, and that they are non-natural objects. We do so in four steps. First we argue that, contrary to common opinion, functions cannot be the cornerstone of a characterisation of artefacts. Our argument suggests an alternative view, which characterises artefacts as objects embedded in what we call use plans. Second, we show that this plan-centred successor of the function-focused view is at odds (...) with the non-naturalness intuition. Third, we show that this intuition can be developed by defining artefacts as produced or human-made objects, but that the resulting definition might collapse into the plan-centred view, and has trouble distinguishing artefact types or kinds. Finally, we propose a division of labour between production and use plans: among objects in general, artefacts are distinguished as human-made objects; within the domain of artefacts, types or kinds are characterised by the use plans in which artefacts are embedded. (shrink)

In recent years, attention for the work of Rudolf Carnap has shifted from polemical discussion to placing Carnap in his intellectual context. Thus, the central question is no longer whether Carnap contributes to solving our current problems, but whether he solved the problems of his day and age. This contextualist approach has resulted in a deeper and more refined understanding of, in particular, Carnap’s early works and has focused on Der logische Aufbau der Welt.

In this paper, I develop a template-based analysis to include several elements of _processes_ through which templates are transferred between fields of inquiry. The analysis builds on Justin Price’s identification of the importance of a “landing zone” in the recipient domain, from which “conceptual pressure” may be created. I will argue that conceptual pressure is a characteristic feature of the process of template transfer; that this means that there are costs to the process of transfer as well as benefits; and (...) that it would be reasonable if modelers try to mitigate these costs. I will discuss two such mitigation strategies: ‘conceptual embedding’ and ‘customization’. I illustrate the claims, focusing on the mitigation strategies, with a case study: that of pioneering applications of reaction–diffusion equations in mathematical ecology. (shrink)

In this paper, it is examined to what extent functions, as analysed in the philosophy of technical artefacts, can serve a role in explaining the aesthetic appreciation of these objects. The main conclusion is that, despite first appearances, so-called ‘Functional Beauty’ accounts cannot derive strength from analyses of artefact functions; on the contrary, these analyses constrain the possibilities for developing a suitable, function-based account of aesthetic appreciation. The paper follows a conceptual-engineering approach. After presenting desiderata for an account of aesthetic (...) appreciation, relevant insights are reviewed that are drawn from philosophical work on artefact functions. Combining the desiderata and insights, three major issues are identified that complicate the relation between function ascriptions to and aesthetic appreciation of technical artefacts. In closing, options are offered for resolving these complications or avoiding them altogether. (shrink)

We argue that Osirak's and Reynaud's technological-reasoning hypothesis raises conceptual and methodological challenges. Interrelations between technical potential and expertise leave it unclear exactly what the technical-reasoning hypothesis encompasses. We submit that it is compatible with a range of hypotheses that are difficult to differentiate empirically.

In this paper we examine the possibilities of combining two central intuitions about artefacts: that they are functional objects, and that they are non-natural objects. We do so in four steps. First we argue that, contrary to common opinion, functions cannot be the cornerstone of a characterisation of artefacts. Our argument suggests an alternative view, which characterises artefacts as objects embedded in what we call use plans. Second, we show that this plan-centred successor of the function-focused view is at odds (...) with the non-naturalness intuition. Third, we show that this intuition can be developed by defining artefacts as produced or human-made objects, but that the resulting definition might collapse into the plan-centred view, and has trouble distinguishing artefact types or kinds. Finally, we propose a division of labour between production and use plans: among objects in general, artefacts are distinguished as human-made objects; within the domain of artefacts, types or kinds are characterised by the use plans in which artefacts are embedded. (shrink)

In this paper, I study the application of phylogenetic analysis in evolutionary archaeology. I show how transfer of this apparently general analytic tool is affected by salient differences in disciplinary context. One is that archaeologists, unlike many biologists, do not regard cladistics as a tool for classification, but are primarily interested in explanation. The other is that explanation is traditionally sought in terms of individual-level rather than population-level mechanisms. The latter disciplinary difference creates an ambiguity in the application and interpretation (...) of phylogenetic analyses. Moreover, I argue that, while archaeologists have claimed that “cladistics is useful for reconstructing artefact phylogenies”, these reconstructions only contribute minimally to the explanatory research agenda of evolutionary archaeology. (shrink)

In this paper, I review Quine's response to the normativity charge against naturalized epistemology. On this charge, Quine's naturalized epistemology neglects the essential normativity of the traditional theory of knowledge and hence cannot count as its successor. According to Quine, normativity is retained in naturalism as ‘the technology of truth-seeking’. I first disambiguate Quine's naturalism into three programs of increasing strength and clarify the strongest program by means of the so-called Epistemic Skinner Box. Then, I investigate two ways in which (...) the appeal to technology as normative enterprise can be made good. I argue that neither coheres with other aspects of Quine's philosophy, most notably the elimination of intentionality. Finally, I briefly consider a third reconstruction of the response, which involves an extension of the web of “belief” to practical know-how. I conclude that the normativity of Quine's (strong) naturalism cannot be found in the technology of truth-seeking. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Die methodische Philosophie Hugo Dinglers und der transzendentale Idealismus Immanuel KantsWybo HoukesKirstin Zeyer. Die methodische Philosophie Hugo Dinglers und der transzendentale Idealismus Immanuel Kants. Hildesheim: Olms, 1999. Pp. 175. Cloth, DM 65.00.History has not been kind to Hugo Dingler. Almost half a century after his death, philosophers of science primarily know him, if at all, from brief remarks in works of Carnap and Popper. Yet anyone who bothers (...) reading Dingler's work can only be struck by the profundity of his attempt to account for developments in mathematics and the sciences—the very factors that shaped, for instance, Carnap's early work.This merits a revival of historical interest in Dingler's philosophy. Yet, in her ambitious first book, Kirstin Zeyer intends to instigate more than that: in the final chapter, she argues that Dingler's "methodical" philosophy is still relevant to contemporary philosophy of science. This may seem a surprising finale to a book devoted to comparing Dingler's thought and Kant's critical philosophy. But in fact there is no topical discontinuity; the earlier, exegetical chapters already carry apologetic overtones and only sketch the historical context of Dingler's work.A mathematician by training and a student of—amongst others—Husserl, his work also shows the influence of Dilthey's analysis of the human will. And as the work of so many philosophers of his generation, Dingler's work was partly shaped by a dialogue with Kant. Therefore, Zeyer's choice of topic is justified. On the other hand, Dingler's background virtually guaranteed that he had to adapt the critical philosophy in places. For example: the criticism of intuition as a source of knowledge was hardly typical of [End Page 607] Dingler, but part of a broad intellectual movement, sometimes called the "crisis of intuition." Therefore, a comparison between Dingler and Kant bears the risk of being rather trivial, unless, for instance, the way in which Dingler adapted Kant is explained in reference to the historical context.Zeyer presents many similarities and differences between Dingler and Kant. Her presentation of Dingler's philosophy is detailed and precise. Dingler's originality, which is amply stressed by Zeyer, lies in his attempt to replace an "intuitive" a priori with a practical one (Herstellungsapriori), which brings out the close connection between knowledge and action, and which focuses on the will rather than the understanding. Unfortunately, however, Zeyer's explication of Kant is less systematic and is more intimately connected to the presentation of Dingler's philosophy than to its own structure. As a result, elements of the critical philosophy surface throughout the book and poignant comparisons, such as between Dingler's and Kant's appeals to "pure synthesis" (29-36), are intermingled by less informative ones, e.g., on the use of regulative ideas of reason (116-126), which fails to bring to light a clear contrast. Moreover, Zeyer presents differences between Dingler and Kant in a rather "internalist" manner, as the result of Dingler's criticism of Kant. Consequently, the emphasis lies on the way in which Dingler corrected Kant's views with respect to a more or less fixed set of problems, rather than on the way in which he attempted to adapt the critical philosophy to changing intellectual circumstances, using elements from phenomenology and Lebensphilosophie. As a result, Zeyer neglects the fact that some of Dingler's central problems, such as that of univocality (e.g., 53) and rejection of ontological presuppositions (45), are not Kantian in origin. At this point, a comparison of Dingler with his contemporaries is indispensable. Again: that certain elements of Kantianism were criticized after 1900 is hardly illuminating, but how the critical philosophy was adapted to the intellectual circumstances by various philosophers is a fascinating topic, as for instance the recent reappraisal of early logical positivism by Michael Friedman and others shows. By approaching her topic in an internalist rather than a contextualist manner, Zeyer misses an opportunity to show the relevance of Dingler's methodical philosophy.This choice of exegetical method is, of course, connected to her ultimate apologetic aim. Contextualizing Dingler's work may show the rationality of some of its elements in his... (shrink)

“Form follows function,” the slogan of modernist architecture, could well be a slogan of artefacts generally. Since the choice of material for a tool is guided by the function of the tool, we may be tempted to think that having a functional nature distinguishes artefacts from natural objects. But that would be a mistake. Certain natural objects—especially biological entities like mammalian hearts—have functional natures too.

Many European countries uphold a ‘high risk of a serious condition’ requirement for limiting the scope of preimplantation genetic diagnosis (PGD). This ‘front door’ rule should be loosened to account for forms of PGD with a divergent proportionality. This applies to both ‘added PGD’ (aPGD), as an add‐on to in vitro fertilization (IVF), and ‘combination PGD’ (cPGD), for a secondary disorder in addition to the one for which the applicants have an accepted PGD indication. Thus loosening up at the front (...) has implications at the back of PGD treatment, where a further PGD rule says that ‘affected embryos’ (in the sense of embryos with the targeted mutation or abnormality) should not be transferred to the womb. This ‘back door’ rule should be loosened to allow for transferring ‘last chance’ affected embryos in aPGD and cPGD cases, provided this does not entail a high risk that the child will have a seriously diminished quality of life. (shrink)

The philosophy of artifacts is as marginal as it is one-sided. The majority of contributions to it are asides in works devoted to other subjects and focus on one characteristic feature: that artifacts are objects with functions. Indeed many artifacts, such as screwdrivers and toasters, come in functional kinds. Perhaps for this reason, philosophers elevated functions to the essences of artifacts or have developed general theories of function to describe artifacts along with their main subject: biological items. Most such theories (...) present one monolithic notion of function that applies to both. Dissident voices claim autonomy for artifact functions, or at least a small measure of conceptual independence, but it is seldom questioned that a theory of artifacts consists merely of a theory of artifact functions. (shrink)

:Academic Medical Centers offer patient care and perform research. Increasingly, AMCs advertise to the public in order to garner income that can support these dual missions. In what follows, we raise concerns about the ways that advertising blurs important distinctions between them. Such blurring is detrimental to AMC efforts to fulfill critically important ethical responsibilities pertaining both to science communication and clinical research, because marketing campaigns can employ hype that weakens research integrity and contributes to therapeutic misconception and misestimation, undermining (...) the informed consent process that is essential to the ethical conduct of research. We offer ethical analysis of common advertising practices that justify these concerns. We also suggest the need for a deliberative body convened by the Association of American Medical Colleges and others to develop a set of voluntary guidelines that AMCs can use to avoid in the future, the problems found in many current AMC advertising practices. (shrink)

Until the late twentieth century, there were three main political currents in the Netherlands: Christian, Labor, and Liberal, giving Christian party politics a stronger position than in European countries with a binary division between conservative and progressive. The history of the debate about embryo research coincides with the end of this period. Whereas in the 1980s the Christian Democrat party still had strong religiously motivated views about embryo protection, it has since lost both the power and the drive to pursue (...) this. However, due to strategic opportunities arising in the margin of Dutch coalition politics, smaller parties inspired by Christian belief are still quite influential on issues of medical ethics in the highly fragmented political landscape of the present. (shrink)

Developments in Non-Invasive Prenatal Testing (NIPT) and cell-free fetal DNA analysis raise the possibility that antenatal services may soon be able to support couples in non-invasively testing for, and diagnosing, an unprecedented range of genetic disorders and traits coded within their unborn child’s genome. Inevitably, this has prompted debate within the bioethics literature about what screening options should be offered to couples for the purpose of reproductive choice. In relation to this problem, the European Society of Human Genetics (ESHG) and (...) American Society of Human Genetics (ASHG) tentatively recommend that any expansion of this type of screening, as facilitated by NIPT, should be limited to serious congenital and childhood disorders. In support of this recommendation, the ESHG and ASHG cite considerations of distribution justice. Notably, however, an account of justice in the organization and provision of this type of screening which might substantiate this recommendation has yet to be developed. This paper attempts to redress this oversight through an investigation of Norman Daniels’ theory of Just health: meeting health needs fairly. In line with this aim, the paper examines what special moral importance (for Just health) screening for the purpose of reproductive choice might have where concerning serious congenital and childhood disorders in particular. The paper concludes that screening for reproductive choice where concerning serious congenital and childhood disorders may be important for providing women with fair opportunity to protect their health (by either having or not having an affected child). (shrink)

Emerging biotechnology may soon allow the creation of genetically human organs inside animals, with non-human primates and pigs being the best candidate species. This prospect raises the question of whether creating organs in primates in order to then transplant them into humans would be more acceptable than using them for research. In this paper, we examine the validity of the purported moral distinction between primates and other animals, and analyze the ethical acceptability of using primates to create organs for human (...) use. (shrink)

Background Massively parallel sequencing techniques, such as whole exome sequencing (WES) and whole genome sequencing (WGS), may reveal unsolicited findings (UFs) unrelated to the diagnostic aim. Such techniques are frequently used for diagnostic purposes in pediatric cases of developmental delay (DD). Yet policy guidelines for informed consent and return of UFs are not well equipped to address specific moral challenges that may arise in these children’s situations. Discussion In previous empirical studies conducted by our research group, we found that it (...) is sometimes uncertain how children with a DD will develop and whether they could come to possess capacities for autonomous decision-making in the future. Parents sometimes felt this brought them into a Catch-22 like situation when confronted with choices about UFs before undergoing WES in trio-analysis (both the parents’ and child’s DNA are sequenced). An important reason for choosing to consent to WES was to gain more insight into how their child might develop. However, to make responsible choices about receiving or declining knowledge of UFs, some idea of their child’s future development of autonomous capacities is needed. This undesirable Catch-22 situation was created by the specific policy configuration in which parents were required to make choices about UFs before being sequencing (trio-analysis). We argue that this finding is relevant for reconfiguring current policies for return of UFs for WES/WGS and propose guidelines that encompass two features. First, the informed consent process ought to be staged. Second, differing guidelines are required for withholding/disclosing a UF in cases of DD appropriate to the level of confidence there is about the child’s future developmental of autonomous capacities. Conclusion When combined with a dynamic consent procedure, these two features of our guidelines could help overcome significant moral challenges that present themselves in the situations of children undergoing genomic sequencing for clarifying a DD. (shrink)

Nudging is a tool of libertarian paternalism. It involves making use of certain psychological tendencies in order to help people make better decisions without restricting their freedom. However, some have argued that nudging is objectionable because it interferes with, or undermines, the rational decision-making of the nudged agents. Opinions differ on why this is objectionable, but the underlying concerns appear to begin with nudging’s threat to rational decision-making. Those who discuss this issue do not make it clear to what this (...) threat to rationality amounts. In this paper I evaluate what effect nudging has on our decision-making and I argue that it does not typically interfere with our rationality in a problematic way. Perhaps nudging is objectionable for other reasons, but we should not argue that nudging is objectionable based on concerns about rational decision-making. (shrink)