In this article, I am concerned with the relationship between the visibility of race as color, the memory of injustice, and American identity. The visibility of color would seem to make it a daily reminder of race and its history, and in this way to be intimately a part of American memory and identity. Yet the tie between memory and color is anything but certain or transparent. Rather, as I shall argue, it is a latticework composed of things remembered, forgotten, (...) glossed, or idealized, and the traces they leave in our world, traces that keep that past from falling into the oblivion of forgetfulness. Finally, color, memory, and identity together belong to the struggle over racial justice in this country, a battle in part to recognize the past, of which color is the visible reminder, and to fashion an American identity that does not seek to render it invisible. Ralph Ellison's writings on memory and race, and particularly his defining work, the "Invisible Man," map these issues and some of the ways of approaching them. The present essay is an exploration of those issues, conducted through an engagement with his work. (shrink)

In this article, I am concerned with the relationship between the visibility of race as color, the memory of injustice, and American identity. The visibility of color would seem to make it a daily reminder of race and its history, and in this way to be intimately a part of American memory and identity. Yet the tie between memory and color is anything but certain or transparent. Rather, as I shall argue, it is a latticework composed of things remembered, forgotten, (...) glossed, or idealized, and the traces they leave in our world, traces that keep that past from falling into the oblivion of forgetfulness. Finally, color, memory, and identity together belong to the struggle over racial justice in this country, a battle in part to recognize the past, of which color is the visible reminder, and to fashion an American identity that does not seek to render it invisible. Ralph Ellison's writings on memory and race, and particularly his defining work, the Invisible Man, map these issues and some of the ways of approaching them. The present essay is an exploration of those issues, conducted through an engagement with his work. (shrink)

In this essay, I argue that the political community's identity and its sense of its own coherence as a responsible agent across time rest squarely on the work of collective memory. The protean volatility of the politics of memory reminds us that in our world , memory is intertwined with power, interest and resistance precisely because it is so vital and fundamental to what we are as citizens and to what our society is a community of justice.

The generation of asymmetric cell shapes is a recurring theme in biology. In budding yeast, one form of cell asymmetry occurs for division and is generated by anisotropic growth of the mother cell to form a daughter cell bud. Previous genetic studies uncovered key roles for the small GTPase Cdc42 in organizing the actin cytoskeleton and vesicle delivery to the site of bud growth,1,2 but a recent paper has also raised questions about how control of Cdc42 activity is integrated into (...) a proposed hierarchical regulatory pathway that specifies a unique site of bud formation.3 BioEssays 25:833–836, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

We hypothesize that aspects of animal multicellularity originated before the divergence of metazoans from fungi and social amoebae. Polarized epithelial tissues are a defining feature of metazoans and contribute to the diversity of animal body plans. The recent finding of a polarized epithelium in the non‐metazoan social amoeba Dictyostelium discoideum demonstrates that epithelial tissue is not a unique feature of metazoans, and challenges the traditional paradigm that multicellularity evolved independently in social amoebae and metazoans. An alternative view, presented here, is (...) that the common ancestor of social amoebae, fungi, and animals spent a portion of its life cycle in a multicellular state and possessed molecular machinery necessary for forming an epithelial tissue. Some descendants of this ancestor retained multicellularity, while others reverted to unicellularity. This hypothesis makes testable predictions regarding tissue organization in close relatives of metazoans and provides a novel conceptual framework for studies of early animal evolution.Editor's suggested further reading in BioEssays Searching for Eve: Basal metazoans and the evolution of multicellular complexity Abstract. (shrink)

Beta‐catenin is a multifunctional protein with critical roles in cell‐cell adhesion, Wnt‐signaling and the centrosome cycle. Whereas the roles of β‐catenin in cell‐cell adhesion and Wnt‐signaling have been studied extensively, the mechanism(s) involving β‐catenin in centrosome functions are poorly understood. β‐Catenin localizes to centrosomes and promotes mitotic progression. NIMA‐related protein kinase 2 (Nek2), which stimulates centrosome separation, binds to and phosphorylates β‐catenin. β‐Catenin interacting proteins involved in Wnt signaling such as adenomatous polyposis coli, Axin, and GSK3β, are also localized at (...) centrosomes and play roles in promoting mitotic progression. Additionally, proteins associated with cell‐cell adhesion sites, such as dynein, regulate mitotic spindle positioning. These roles of proteins at the cell cortex and Wnt signaling that involve β‐catenin indicate a cross‐talk between different sub‐cellular sites in the cell at mitosis, and that different pools of β‐catenin may co‐ordinate centrosome functions and cell cycle progression. (shrink)

Integrins are ubiquitous trans‐membrane adhesion molecules that mediate the interaction of cells with the extracellular matrix (ECM). Integrins link cells to the ECM by interacting with the cell cytoskeleton. In cases such as leukocyte binding, integrins mediate cell‐cell interactions and cell‐ECM interactions. Recent research indicates that integrins also function as signal transduction receptors, triggering a number of intracellular signaling pathways that regulate cell behavior and development. A number of integrins are known to stimulate changes in intracellular calcium levels, resulting in (...) integrin activation. Although changes in intracellular calcium regulate a vast number of cellular functions, this review will discuss the stimulation of calcium signaling by integrins and the role of intracellular calcium in the regulation of integrin‐mediated adhesion. (shrink)

Machine generated contents note: PART I: OVERVIEW OF KEY INTERNATIONAL EDUCATION POLICY DEBATES * PART II: THE ROLE OF POLICY IN SOCIAL JUSTICE DEBATES * PART III: POLICY DEBATES IN INTERNATIONAL HIGHER EDUCATION * PART IV: EDUCATION POLICY DEBATES WITH LASTING CONSEQUENCES.

Die ATB ist die traditionsreichste Editionsreihe der germanistischen Mediävistik. Begründet 1881 von Hermann Paul, wurde sie von führenden Fachvertretern, Georg Baesecke, Hugo Kuhn, Burghart Wachinger, betreut. Seit 2001 liegt die Verantwortung in den Händen von Christian Kiening. Die mittlerweile etwa 120 Bände verknüpfen exemplarisch Handschriftennähe und Lesbarkeit, wissenschaftliche Arbeit am Text und Blick auf die akademische Lehre. Sie umfassen anerkannte, zum Teil kommentierte Ausgaben 'klassischer' Autoren der Zeit um 1200, aber auch veritable Werkausgaben (Notker der Deutsche) und anspruchsvolle Neueditionen (Eckenlied, (...) Heinrich von dem Türlin). (shrink)

The Altdeutsche Textbibliothek [Old German Text Library] is the series of editions of German medieval texts with the richest history. Foundedin 1881 by Hermann Paul, it has been edited by leading Germanists- Georg Beasecke, Hugo Kuhn, Burghart Wachinger. Since 2001, responsibility for the series has rested with Christian Kiening. In the meantime, the series comprises some 120 volumes, with an exemplary combination of closeness to the original manuscript(s) with ease of reading, philological accuracy with concern for university teaching. It includes (...) recognised editions of "classical" authors from around 1200- some with commentary- but also presents veritable editions of authors' works (Notker the German) and high-quality new editions (Eckenlied, Heinrich von dem Türlin). (shrink)

How reasonable and rational can science be when its practitioners speak of "revolutions" in their thinking and extol certain theories for their "beauty"? James W. McAllister addresses this question with the first systematic study of the aesthetic evaluations that scientists pass on their theories. P. A. M. Dirac explained why he embraced relativity by saying, "It is the essential beauty of the theory which I feel is the real reason for believing in it." Dirac's claim seems to belie rationalist (...) accounts of science. Using this and a wealth of other historical examples, McAllister explains how scientists' aesthetic preferences are influenced by the empirical track record of theories, describes the origin and development of aesthetic styles of theorizing, and reconsiders whether simplicity is an empirical or an aesthetic virtue of theories. McAllister then advances an innovative model of scientific revolutions, in opposition to that of Thomas S. Kuhn. Three detailed studies demonstrate the interconnection of empirical performance, beauty, and revolution. One examines the impact of new construction materials on the history of architecture. Another reexamines the transition from the Ptolemaic system to Kepler's theory in planetary astronomy, and the third documents the rise of relativity and quantum theory in the twentieth century. (shrink)

This chapter contains section titled: Intervention and Human Rights.

In this companion volume to The Universe Next Door, James W. Sire offers his refined definition of a worldview and addresses key questions about the history of worldview thinking, the existential and intellectual formation of worldviews, the public and private dimensions of worldviews and how worldview thinking can help us navigate an increasingly pluralistic universe.

This book is a manuscript that was virtually complete when James W. Cornman died. Most of the chapters were in final form, and all but the last had been revised by the author. The last chapter was in handwritten form, and the concluding remarks were not finished. Swain took charge of the proofreading and John L. Thomas compiled the indices with the assistance of Lehrer. It is our opinion that this manuscript, like the other books Cornman published, is one (...) of exceptional scholarly and philo sophical importance. As do all of his philosophical publications, this work reflects Cornman's great love for philosophy and his commitment to the search for truth. Every serious student and author of epistemology will benefit from and admire the thorough scholarship and rigorous argumentation they will find herein. It has been our privilege to partici pate in the preparation of the manuscript for the philosophical public. KEITH LEHRER MARSHALL SWAIN IX INTRODUCTION INTRODUCTION TO EPISTEMOLOGICAL SKEPTICISM Many philosophers try to refute skepticism, but few try to give a precise characterization of the thesis they attack. My first aim, consequently, is to characterize skepticism, or, more precisely, several species of skepticism. Then I shall choose those species I wish to consider and justify my choice. To begin, let me distinguish what I shall call "epistemological skepticism" from the thesis I shall call "ontological nihilism" and from what is believed by someone whom I shall call an "ontological skeptic". (shrink)

Somatic or inherited mutations in the adenomatous polyposis coli (APC) gene are a frequent cause of colorectal cancer in humans. APC protein has an important tumor suppression function to reduce cellular levels of the signaling protein β‐catenin and, thereby, inhibit β‐catenin and T‐cell‐factor‐mediated gene expression. In addition, APC protein binds to microtubules in vertebrate cells and localizes to actin‐rich adherens junctions in epithelial cells of the fruit fly Drosophila (Fig. 1). Very little is known, however, about the function of these (...) cytoskeletal associations. Recently, Hamada and Bienz have described a potential role for Drosophila E‐APC in cellular adhesion,1 which offers new clues to APC function in embryonic development, and potentially colorectal adenoma formation and tumor progression in humans. BioEssays 24:771–774, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

A brief study on the lies spread by the devil and the truth found in God's Word.

For more than forty years, The Universe Next Door has set the standard for an introduction to worldviews. This sixth edition uses James Sire's widely influential model of eight basic worldview questions to examine prominent worldviews that have shaped the Western world, critiquing each worldview within its own frame of reference and in comparison to others.

Three experts collaborate in this passionate and rewarding dialogue on the legacy of the great American philosopher and educator John Dewey (1859 1952). Focused on growth and the creation of value within the context of real life, Dewey s pragmatic philosophy shares much with humanistic Buddhism. These similarities, which arise throughout the book, add richness to a dialogue already overflowing with faith in our capacity to find common ground and expand human well being in our rapidly globalizing world. For Dewey, (...) individual and social potential alike are unlimited. Readers will come away ready to embrace rather than fear the increasing complexity of our world.". (shrink)

To know Him is to love Him -- God as our personal father -- The unfolding revelation of God -- God's amazing attributes -- The Messiah has come! -- Wonderful Messiah, son of God -- The person of the Holy Spirit -- Holy Spirit, you are welcome here! -- Knowing God by knowing His word -- Knowing the master builder -- God's trustworthy word -- Hungry for his every word -- The uniqueness of God's word -- Getting to know God.

It is commonly asserted that “death is not a welfare issue” and this has been reflected in welfare legislation and policy in many countries. However, this creates a conflict for many who consider animal welfare to be an appropriate basis for decision-making in animal ethics but also consider that an animal’s death is ethically significant. To reconcile these viewpoints, this paper attempts to formulate an account of death as a welfare issue. Welfare issues are issues that refer to evaluations concerning (...) an animal’s interests. This includes evaluations that refer only to comparisons between the presence and absence of states, including positive states. This means that an animal’s death may be a welfare issue insofar as it leads to the exclusion of relevant positive states. This allows us to deny that death is necessarily not a welfare issue. (shrink)

This fully revised and extended edition of James Nickel's classic study explains and defends the conception of human rights found in the Universal Declaration of Human Rights and subsequent human rights treaties. Combining philosophical, legal, and political approaches, Nickel addresses questions about what human rights are, what their content should be, and whether and how they can be justified.

The Farm Animal Welfare Council’s concept of a Good Life gives an idea of an animal’s quality of life that is over and above that of a mere life worth living. The concept needs explanation and clarification, in order to be meaningful, particularly for consumers who purchase farm animal produce. The concept could allow assurance schemes to apply the label to assessments of both the potential of each method of production, conceptualised in ways expected to enhance consumers’ engagement such as (...) ‘naturalness’ and ‘freedom’; and the concept of a life worth living as a safeguard threshold below which no animal’s actual welfare should fall, based on each animal’s overall affective states. This may provide a framework for development of the Good Life concept, within scientific and sociological fields, in order to allow reliable and influential use by assessors, consumers and retailers. (shrink)

Animals are usually considered to lack the status of autonomous agents. Nevertheless, they do appear to make ostensible choices. This article considers whether, and how, I should respect animals' choices. I propose a concept of volitionality which can be respected if, and insofar as, doing so is in the best interests of the animal. Applying that concept, I will argue that an animals' choices be respected when the relevant human decision maker's capacities to decide are potentially challenged or compromised. For (...) example, it will be best to respect the animals' choice when the human decision maker: lacks accurate knowledge of the animal's subjective experiences; does not know what will lead to desirable experiences or allow for the avoidance of undesirable ones; is biased; is less aware of the animal's specific situation; cannot appreciate all elements comprehensively, including considering any value to the animal being allowed to make and implement a choice, such as where a lack of control or liberty would be unpleasant or where an animal would usefully learn from the process of choice-making; and when the animal's choice is achievable. This additionally suggests that we may often beneficially choose to set up situations that empower animals to make better choices. (shrink)

This article explores the process of teaching Christian theological ethics beyond the common focus on European and North American sources. In conversation with moves to decolonise university curricula, the article proposes a theology of listening, an example of a research seminar for master’s and doctoral students at the University of Aberdeen on Christian ethics beyond Europe and North America, and an exploration of broader challenges for the formation of the theologian. The article asks, what can we learn when we give (...) up power and control when teaching and learning theology? How can we shift our methods of knowing and practising theology? We write as theologians from India, Mexico, and the United States living in the United Kingdom. We reflect on forms of exclusion in theological method and formation that arise from colonising, systemic violence, and inequalities. The article considers intercultural challenges when encountering different methods of reflection on the Christian experience. In a search for a more profoundly theological approach, we propose listening to the other as integral to doing theology. In an intercultural move, we draw on Dietrich Bonhoeffer's theology of listening, proposing that theology must be an advent of voices from beyond our usual places and methods. (shrink)

Are humans free, or are we determined by our genes and the world around us? The question of freedom is not only one of philosophy’s greatest conundrums, but also one of the most fundamental questions of human existence. It’s particularly pressing in societies like ours, where our core institutions of law, ethics, and religion are built around the belief in individual freedom. Can one still affirm human freedom in an age of science? And if free will doesn’t exist, does it (...) make sense to act as though it does? These are the issues that are presented, probed, and debated in the following chapters. A dozen experts―specialists in medicine, psychology, ethics, theology, and philosophy—grapple with the multiple and often profound challenges presented by today’s brain science. After examining the arguments against traditional notions of free will, several of the authors champion the idea of a chastened but robust free will for today, one that allows us still to affirm the value of first-person experience. (shrink)

Bogen and Woodward claim that the function of scientific theories is to account for 'phenomena', which they describe both as investigator-independent constituents of the world and as corresponding to patterns in data sets. I argue that, if phenomena are considered to correspond to patterns in data, it is inadmissible to regard them as investigator-independent entities. Bogen and Woodward's account of phenomena is thus incoherent. I offer an alternative account, according to which phenomena are investigator-relative entities. All the infinitely many patterns (...) that data sets exhibit have equal intrinsic claim to the status of phenomenon: each investigator may stipulate which patterns correspond to phenomena for him or her. My notion of phenomena accords better both with experimental practice and with the historical development of science. (shrink)

Designed for use by philosophy students, this 2006 book provides an accessible, yet technically sound treatment of modal logic and its philosophical applications. Every effort has been made to simplify the presentation by using diagrams in place of more complex mathematical apparatus. These and other innovations provide philosophers with easy access to a rich variety of topics in modal logic, including a full coverage of quantified modal logic, non-rigid designators, definite descriptions, and the de-re de-dictio distinction. Discussion of philosophical issues (...) concerning the development of modal logic is woven into the text. The book uses natural deduction systems and also includes a diagram technique that extends the method of truth trees to modal logic. This feature provides a foundation for a novel method for showing completeness, one that is easy to extend to systems that include quantifiers. (shrink)

The concept of hegemonic masculinity has influenced gender studies across many academic fields but has also attracted serious criticism. The authors trace the origin of the concept in a convergence of ideas in the early 1980s and map the ways it was applied when research on men and masculinities expanded. Evaluating the principal criticisms, the authors defend the underlying concept of masculinity, which in most research use is neither reified nor essentialist. However, the criticism of trait models of gender and (...) rigid typologies is sound. The treatment of the subject in research on hegemonic masculinity can be improved with the aid of recent psychological models, although limits to discursive flexibility must be recognized. The concept of hegemonic masculinity does not equate to a model of social reproduction; we need to recognize social struggles in which subordinated masculinities influence dominant forms. Finally, the authors review what has been confirmed from early formulations and what needs to be discarded. The authors suggest reformulation of the concept in four areas: a more complex model of gender hierarchy, emphasizing the agency of women; explicit recognition of the geography of masculinities, emphasizing the interplay among local, regional, and global levels; a more specific treatment of embodiment in contexts of privilege and power; and a stronger emphasis on the dynamics of hegemonic masculinity, recognizing internal contradictions and the possibilities of movement toward gender democracy. (shrink)

Designed for use by philosophy students, this book provides an accessible, yet technically sound treatment of modal logic and its philosophical applications. Every effort has been made to simplify the presentation by using diagrams in place of more complex mathematical apparatus. These and other innovations provide philosophers with easy access to a rich variety of topics in modal logic, including a full coverage of quantified modal logic, non-rigid designators, definite descriptions, and the de-re de-dictio distinction. Discussion of philosophical issues concerning (...) the development of modal logic is woven into the text. The book uses natural deduction systems and also includes a diagram technique that extends the method of truth trees to modal logic. This feature provides a foundation for a novel method for showing completeness, one that is easy to extend to systems that include quantifiers. (shrink)

It is nearly 10 years since Patrick Haggard and colleagues first reported the ‘intentional binding’ effect . The intentional binding effect refers to the subjective compression of the temporal interval between a voluntary action and its external sensory consequence. Since the first report, considerable interest has been generated and a fascinating array of studies has accumulated. Much of the interest in intentional binding comes from the promise to shed light on human agency. In this review we survey studies on intentional (...) binding, focusing, in particular, on the link between intentional binding and the sense of agency . We suggest that, whilst it is yet to be fully explicated, the link between intentional binding and the sense of agency is compelling. We conclude by considering outstanding questions and future directions for research on intentional binding. (shrink)

What do the rules of logic say about the meanings of the symbols they govern? In this book, James W. Garson examines the inferential behaviour of logical connectives, whose behaviour is defined by strict rules, and proves definitive results concerning exactly what those rules express about connective truth conditions. He explores the ways in which, depending on circumstances, a system of rules may provide no interpretation of a connective at all, or the interpretation we ordinarily expect for it, or (...) an unfamiliar or novel interpretation. He also shows how the novel interpretations thus generated may be used to help analyse philosophical problems such as vagueness and the open future. His book will be valuable for graduates and specialists in logic, philosophy of logic, and philosophy of language. (shrink)

I address the question: “What is fixed on the boundary in the action principles of general relativity?” Four forms of the action are considered: the Einstein action, the Hilbert action, the first order action, and what may be called the cosmological action. The relationships and boundary data of these actions are described geometrically. Formal passage to the “Euclidean” forms of these actions is effected in detail.