The motto of the Royal Society—Nullius in verba—was intended to highlight the members’ rejection of received knowledge and the new place they afforded direct empirical evidence in their quest for genuine, useful knowledge about the world. But while many studies have raised questions about the construction, reception and authentication of knowledge, Evidence in the Age of the New Sciences is the first to examine the problem of evidence at this pivotal moment in European intellectual history. What constituted evidence—and for whom? (...) Where might it be found? How should it be collected and organized? What is the relationship between evidence and proof? These are crucial questions, for what constitutes evidence determines how people interrogate the world and the kind of arguments they make about it. In this important new collection, Lancaster and Raiswell have assembled twelve studies that capture aspects of the debate over evidence in a variety of intellectual contexts. From law and theology to geography, medicine and experimental philosophy, the chapters highlight the great diversity of approaches to evidence-gathering that existed side by side in the sixteenth and seventeenth centuries. In this way, the volume makes an important addition to the literature on early science and knowledge formation, and will be of particular interest to scholars and advanced students in these fields. (shrink)

This paper establishes the 'emblematic' use of natural history as a propaedeutic to self-betterment in the Renaissance; in particular, in the natural histories of Gessner and Topsell, but also in the works of Erasmus and Rabelais. Subsequently, it investigates how Francis Bacon's conception of natural history is envisaged in relation to them. The paper contends that, where humanist natural historians understood the use of natural knowledge as a preliminary to individual improvement, Bacon conceived self-betterment foremost as a means to Christian (...) charity, or social-betterment. It thus examines the transformation of the moralizing aspect of Renaissance natural history in Bacon's conception of his Great Instauration. (shrink)

Christine Jackson has succeeded in writing the modern biography of Edward Herbert long sought by early modern scholars. Jackson’s Courtier, Scholar, and Man of the Sword paints a rich picture of Ed...

This paper aims to take the measure of the strand of early modern anti-clericalism that was conveyed by the term “priestcraft”. Priestcraft amounted to the claim that priests had usurped civil power and accumulated material wealth by systematically deceiving the laity and its secular rulers. Religion as it was practised and avowed by believers in early modern Europe was left tainted by this charge since manifold aspects of religious practice and belief fell under the pall of the suspicion that they (...) were merely part of the ruse perpetrated through the centuries by greedy and power-hungry priests. While the English language was particularly effective in condensing this claim into the term in question, mistrust of the clergy informed numerous discourses unfolding in diverse confessional and intellectual contexts. The present article seeks to draw attention to the thematic richness of priestcraft as an object of historical inquiry by identifying the multiple ways in which this trope made its presence felt in the early modern world. (shrink)

Abstract. This paper examines the impact of two formalizations of evolutionary biology on the antiselectionist critiques of the Intelligent Design (ID) movement. It looks first at attempts to apply the syntactic framework of the physical sciences to biology in the twentieth century, and to their effect upon the ID movement. It then examines the more heuristic account of biological-theory structure, namely, the semantic model. Finally, it concludes by advocating the semantic conception and emphasizing the problems that the semantic model creates (...) for ID's negative and positive theses. (shrink)

This book offers a comprehensive and unitary study of the philosophy of Francis Bacon, with special emphasis on the medical, ethical and political aspects of his thought. It presents an original interpretation focused on the material conditions of nature and human life. In particular, coverage in the book is organized around the unifying theme of Bacon’s notion of appetite, which is considered in its natural, ethical, medical and political meanings. The book redefines the notions of experience and experiment in Bacon’s (...) philosophy of nature, shows the important presence of Stoic themes in his work as well as provides an original discussion of the relationships between natural magic, prudence and political realism in his philosophy. Bringing together scholarly expertise from the history of philosophy, the history of science and the history of literature, this book presents readers with a rich and diverse contextualization of Bacon’s philosophy. (shrink)

Transoral laser microsurgery applies to the piecemeal removal of malignant tumours of the upper aerodigestive tract using the CO2 laser under the operating microscope. This method of surgery is being increasingly popularised as a single modality treatment of choice in early laryngeal cancers (T1 and T2) and occasionally in the more advanced forms of the disease (T3 and T4), predomi- nantly within the supraglottis. Thomas Kuhn, the American physicist turned philosopher and historian of science, coined the phrase ‘paradigm shift’ in (...) his groundbreaking book The Structure of Scientific Revolutions. He argued that the arrival of the new and often incompatible idea forms the core of a new paradigm, the birth of an entirely new way of thinking. This article discusses whether Steiner and col- leagues truly brought about a paradigm shift in oncological surgery. By rejecting the principle of en block resection and by replacing it with the belief that not only is it oncologically safe to cut through the substance of the tumour but in doing so one can actually achieve better results, Steiner was able to truly revolutionise the man- agement of laryngeal cancer. Even though within this article the repercussions of his insight are limited to the upper aerodigestive tract oncological surgery, his willingness to question other peoples’ dogma makes his contribution truly a genuine paradigm shift. (shrink)

In his paper, “Higher‐order truths about chmess,” Daniel Dennett argues that “[m]any projects in contemporary philosophy are artifactual puzzles of no abiding significance.” In other words, much contemporary academic philosophy is a waste of time. In this chapter, we use mathematics, models, and metaphysics, to expand and clarify Dennett's chmess analogy. We further the argument that some contemporary academic philosophy loses its way and chases chmess‐like endeavors – arguing that philosophy is bloated by extraneous, esoteric, and bizarre philosophical projects that (...) aren't detached from reality but only related to it tangentially. Chmess‐like games, like some contemporary academic philosophy, nick reality and then shoot off on their own trajectory, often down intellectual rabbit holes. (shrink)

Background U.S. federal regulations require that certain ethical elements be followed to protect human research subjects. The location and clinical circumstances of a proposed research study can differ substantially and can have significant implications for these ethical considerations. Both the location and clinical circumstances are particularly relevant for research in intensive care units (ICUs), where patients are often unable to provide informed consent to participate in a proposed research intervention. Purpose Our goal is to elaborate on the updated 2013 U.S. (...) Food and Drug Administration (FDA) guidance document regarding an exemption from the requirement of obtaining informed consent from patients or their surrogates and to address certain elements within that document, thereby assisting clinicians in developing a framework for emergency research in accordance with the regulatory bodies at their own institutions and in the United States. Methods Review of the 2011 and updated FDA guidance document on exemption from informed consent. Results The current process of obtaining informed consent within ICUs needs to be revisited, especially for research in which timely informed consent is not likely. In particular, the process of obtaining informed consent may not be appropriate or even ethical for critically ill patients in extremis who require an intervention for which there is no current acceptable standard of care and clinical equipoise exists. We provide clinicians with a viewpoint that further elaborates on the FDA guidance document. Limitations The viewpoints provided herein are those of the authors and are therefore inherently limited by the personal views of a selected few. Other clinicians or researchers may not interpret the FDA guidelines in a similar manner. Moreover, the discussion of a guideline document is a limitation in and of itself. The guidelines set forth by the FDA are precisely that—guidelines. Therefore, they may not be followed as outlined in the guidance document within one’s own institution. Our goal is that, by elaborating on the guidelines for planned research involving human subjects in the ICU, institutional regulatory bodies may gain a better understanding in drafting their own document when faced with a clinician or a researcher who wishes to conduct planned research in an ICU. Conclusions We believe that the interpretations provided will allow clinicians to safely undertake planned research in ICUs without endangering the main tenets of ethical research involving human participants. This research is needed for the advancement of care in the critically ill. (shrink)

Two cross-modal experiments provide partial support for O'Regan & Noë's (O&N's) claim that sensorimotor contingencies mediate perception. Differences in locating a target sound accompanied by a spatially disparate neutral light correlate with whether the two stimuli were perceived as spatially unified. This correlation suggests that internal representations are necessary for conscious perception, which may also mediate sensorimotor contingencies.

What is medical progress? The answer to this question is often associated with advances in diagnostic technology, with greater understanding of disease or pathological mechanisms particularly at the molecular level, or with the discovery of drugs and the developmental of surgical procedures to treat diseases. However, this facile answer can be problematic. In a New York Times Magazine article, for example, Lisa Sanders (2003) recounts a lecture delivered to her first-year class, at a "white-coat" ceremony, by the medical school dean. (...) Half of what we—the faculty—teach you—the students—is nonsense, she was told, but we don't know which half. She illustrates what the dean said, with the following change in advice for .. (shrink)

From the start, Americans were wrestling with the proper connections between "private and public felicity." On its face, the first line of the First Amendment to the Constitution seems to settle the issue: "Congress shall make no law respecting the establishment of religion or prohibiting the free exercise thereof." Thomas Jefferson declared that this provision "buil[t] a wall of separation between church and state." While the proscription against meddling with religion originally applied only to the national government, the Fourteenth Amendment (...) extended the Constitution—and, in theory, Jefferson's wall—to the state governments. But the Constitution is just the start of the story. America's boisterous, protean religious life sends waves of fervor breaking against Jefferson's wall. Religious fervor provokes moralistic attitudes that filter through American politics. This paper examines the reach of this moralizing effect with a glance at two very unlikely—that is, apparently secular—policy domains: health care and jails. (shrink)

Why do bad things happen, even to good people? If there is a God, why aren't God's existence and God's will for humans more apparent? And if God really does miracles for some people, why not for others? This book examines these three problems of evil - suffering, divine hiddenness, and unfairness if miracles happen as believers claim - to explore how different ideas of God's power relate to the problem of evil.

The issue addressed in this thesis is one in the absolute idealism of Spinoza. It is one of specifying an interpretation of substance-attribute identity as a solution to the problem of reconciling it with the diversity of the attributes and the oneness of substance. As a testing ground for any proposed solution, a list of questions is generated. Given the countable diversity of the attributes, can we conceive of the identity of each of them with the one substance? Why, if (...) I am identical to a mode of each of infinite attributes, do I perceive only a body? What is the rational explanation for the infinite countable diversity of the attributes and our being directly acquainted with only two? In what manner can we reconcile the divisibility of substance with the activity of thought? How does one reconcile the order of extension seeming to be one of external relations with the essentially internal order of any finite thinking thing? How does one reconcile the independent being of modes of extension with the truth-functionality of ideas? In what manner is it possible to understand the appearance of the uniqueness of the one thing conceived under the idea of the body and the one-among-severalness of the same thing conceived under the idea of the individual's mind? In what manner can it be said that substance, consisting of infinite attributes, is accurately and completely conceived through any one of them while each is conceptually independent of every other? How can the one thing which is mind and body be wholly and accurately conceived to be a mode of either of their respective attributes while modes of differing attributes are also conceptually independent? The interpretations of substance-attribute identity given by John Clark Murray, T. L. S. Sprigge, and Errol E. Harris, in their writings in which they advocate reading Spinoza as an absolute idealist, are argued to be disadvantageous in dealing with the evident parallelism of the attributes. Finally, a proposed solution, offered by an alternative absolute idealist interpretation of substance-attribute identity, is developed in response to each of the above questions. (shrink)

The task of visual search is to determine as rapidly as possible whether a target item is present or absent in a display. Rapidly detected items are thought to contain features that correspond to primitive elements in the human visual system. In previous theories, it has been assumed that visual search is based on simple two-dimensional features in the image. However, visual search also has access to another level of representation, one that describes properties in the corresponding three-dimensional scene. Among (...) these properties are three dimensionality and the direction of lighting, but not viewing direction. These findings imply that the parallel processes of early vision are much more sophisticated than previously assumed. (shrink)

This article advances the theoretical and practical value of workplace spirituality by drawing on person–organization (PO) fit theory and transpersonal psychology to investigate three questions: (a) What antecedents lead individuals and organizations to seek and foster workplace spirituality? (b) What are the perceived spiritual needs of individuals, and how are those needs fulfilled in the workplace? and (c) What are the consequences of meeting spiritual needs as individuals perceive them? Using constructivist grounded theory, analysis of interview data from thirty-four participants (...) located in organizations across the Netherlands, Ireland, the United Kingdom, and Portugal led to development of a workplace spirituality, PO fit model in which we propose reconciling self as a core factor of workplace spirituality. We note how through the process of reconciling self, workplace spirituality is related to meaning making and how an individual perceives their work environment as conducive to self-expression and inner purpose. Practical and theoretical implications are discussed, as are limitations of the study and ideas for future research. (shrink)

Previous theories of early vision have assumed that visual search is based on simple two-dimensional aspects of an image, such as the orientation of edges and lines. It is shown here that search can also be based on three-dimensional orientation of objects in the corresponding scene, provided that these objects are simple convex blocks. Direct comparison shows that image-based and scene-based orientation are similar in their ability to facilitate search. These findings support the hypothesis that scene-based properties are represented at (...) preattentive levels in early vision. (shrink)

It has generally been assumed that rapid visual search is based on simple features and that spatial relations between features are irrelevant for this task. Seven experiments involving search for line drawings contradict this assumption; a major determinant of search is the presence of line junctions. Arrow- and Y-junctions were detected rapidly in isolation and when they were embedded in drawings of rectangular polyhedra. Search for T-junctions was considerably slower. Drawings containing T-junctions often gave rise to very slow search even (...) when distinguishing arrow- or Y-junctions were present. This sensitivity to line relations suggests that preattentive processes can extract 3-dimensional orientation from line drawings. A computational model is outlined for how this may be accomplished in early human vision. (shrink)

How should we incorporate algorithms into humanistic scholarship? The typical approach is to clone what humans have done but faster, extrapolating expert insights to landfills of source material. But creative scholars do not clone tradition; instead, they produce readings that challenge closely held understandings. We theorize and then illustrate how to construct bad robots trained to surprise and provoke. These robots aren’t the most human but rather the most alien—not tame but dangerous. We explore the relationship between the reproduction of (...) tradition and the generation of surprise and then show how formalizing a particular humanistic theory as a Bayesian prior allows us to identify readings that disrupt it through a process of algorithmic abduction. Among the exploding universe of surprising (and mostly ridiculous) possible readings, algorithmic efficiency allows us to select readings that nonetheless garner substantial support from the total archive and so merit interpretation and engagement. It is in such interaction between alien and human readers that meaning is made and understanding disturbed; it is by extending alien readings to novel texts that the scholarly community tests the value of those readings. (shrink)

In this paper, we report on the development and validity of the Professional Decision-Making in Research measure, a vignette-based test that examines decision-making strategies used by investigators when confronted with challenging situations in the context of empirical research. The PDR was administered online with a battery of validity measures to a group of NIH-funded researchers and research trainees who were diverse in terms of age, years of experience, types of research, and race. The PDR demonstrated adequate reliability and parallel form (...) correlation. As hypothesized, the PDR was significantly negatively correlated with narcissism, cynicism, moral disengagement, and compliance disengagement; it was not correlated with socially desirable responding. In regression analysis, the strongest predictors of higher PDR scores were low compliance disengagement, speaking English as a native language, conducting clinical research with human subjects, and low levels of narcissism. Given that the PDR was written at an eighth grade reading level to be suitable for use with English as a second language participants and that only one-fourth of items focused on clinical research, further research into the possible roles of culture and research ethics training across specialties is warranted. This initial validity study demonstrates the potential usefulness of the PDR as an educational outcome assessment measure and a research instrument for studies on professionalism and integrity in research. (shrink)