We develop an axiomatic set theory — the Theory of Hyperfinite Sets THS— which is based on the idea of the existence of proper subclasses of large finite sets. We demonstrate how theorems of classical continuous mathematics can be transfered to THS, prove consistency of THS, and present some applications.

We introduce and discuss a concept of approximation of a topological algebraic system A by finite algebraic systems from a given class K. If A is discrete, this concept agrees with the familiar notion of a local embedding of A in a class K of algebraic systems. One characterization of this concept states that A is locally embedded in K iff it is a subsystem of an ultraproduct of systems from K. In this paper we obtain a similar characterization of (...) approximability of a locally compact system A by systems from K using the language of nonstandard analysis. In the signature of A we introduce positive bounded formulas and their approximations; these are similar to those introduced by Henson [14] for Banach space structures (see also [15, 16]). We prove that a positive bounded formula φ holds in A if and only if all precise enough approximations of φ hold in all precise enough approximations of A. We also prove that a locally compact field cannot be approximated arbitrarily closely by finite (associative) rings (even if the rings are allowed to be non-commutative). Finite approximations of the field R can be considered as possible computer systems for real arithmetic. Thus, our results show that there do not exist arbitrarily accurate computer arithmetics for the reals that are associative rings. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

There have been recent concerns about an “epidemic of loneliness” during the pandemic, given the pervasiveness of loneliness in the population and its harmful effects on health and well-being. Therefore, it is important to establish the correlates of loneliness. The purpose of the current study was to explore how loneliness relates to a construct termed mattering, which is the feeling of being important to other people. Mattering was assessed with multiple measures in the current study (e.g., mattering in general, fears (...) of not mattering, and mattering to peers). A sample of 172 female psychology undergraduate students aged 18–25 years completed self-report measures of general mattering, mattering to peers, anti-mattering, fear of not mattering, and state and trait loneliness. As predicted, lower levels of both general mattering and mattering to peers were associated with higher state loneliness. Higher feelings of anti-mattering (feelings of being invisible and insignificant to others) and fears of not mattering were associated with greater trait loneliness, as well as a reduced sense of mattering to friends. The findings illustrate that feeling as though one does not matter to others (i.e., feeling insignificant and unimportant) is associated with increased state and trait loneliness among young women. Implications are discussed for loneliness theory and how these results can enhance both clinical understanding and practice. (shrink)

SummaryIn this article, I offer a series of responses to comments by four scholars on my book, Continental Divide: Heidegger, Cassirer, Davos. In my remarks, I take up various questions of both methodology and interpretation, clarifying, for example, why the term “Continental” still seems to me an apt description for the philosophies of both Cassirer and Heidegger, how the two thinkers related to the tradition of philosophical anthropology, how each philosopher conceived of the relation between myth and science, and so (...) forth. Along the way, I also clarify why the terms “spontaneity” and “thrownness” still strike me as helpful for distinguishing between the two rival philosophies, and I explain why it is misguided to believe that philosophical disputes must conclude in dialectical reconciliation. (shrink)

Martin Heidegger devotes extensive discussion to medieval philosophers, particularly to their treatment of Truth and Being. On both these topics, Heidegger accuses them of forgetting the question of Being and of being responsible for subjugating truth to the modern crusade for certainty: ‘truth is denied its own mode of being’ and is subordinated ‘to an intellect that judges correctly’. Though there are some studies that discuss Heidegger’s debt to and criticism of medieval thought, particularly that of Thomas Aquinas, there is (...) no constructive reply to his assertions. As a result, Heidegger’s critique had an unprecedented effect on the credibility of medieval philosophy, whereby great portions of the philosophical community dismiss it altogether as an illegitimate Onto‐Theology. It is the aim of this study to offer a constructive reply that will fundamentally grapple with these allegations. By constructive reply we mean not only a reply that avoids the problems Heidegger raises regarding existence, essence and truth, but more importantly, one that uses Heidegger’s criticism in order to present a more insightful account of these notions. The present study is composed of two parts where the second serves as a sort of addendum. The first part, the core of this study, is an attempt to develop an understanding of the distinction between essence and existence that, on the one hand, accords with Heidegger’s criticism while on the other hand advances our understanding of how we think and understand reality. After presenting Heidegger’s depiction of Aquinas’s distinction between essence and existence (esse) as a real distinction, the study will present several views propounded by scholars of Aquinas regarding the status of this distinction. It will be argued that it is not clear whether the distinction is real, formal or conceptual, and that different types of distinction are applied in different places, particularly in regard to the phantasm that Aquinas considers essential to the human act of thinking. The second part diverges from the first part and focuses on Heidegger’s criticism of Aquinas’s conception of truth as adequation, i.e., what it is that grounds the possibility of truth as adequation. This divergence is necessary in order to present a full metaphysical response to Heidegger’s criticism. Since the aim of the present study is to argue that Aquinas’s philosophical system can contend with Heidegger’s criticism, a partial reply would greatly diminish its effectiveness. (shrink)

The purpose of cause-related marketing (CRM) is to publicise and capitalise on a firm's corporate social performance (CSP) by enhancing its legitimacy in the eyes of its stakeholders. This study focuses on the firm's internal stakeholders - i.e. its employees - and the extent of their involvement in the selection of social campaigns. Whilst the difficulties of managing a firm that has lost or damaged its legitimacy in the eyes of its employees are well known, little is understood about the (...) extent to which managers and their social partners listen to and involve their employees in the legitimation process. Through telephone interviews with non-profit organisations and senior managers of service sector firms, the extent of employee involvement in CRM campaigns and the perceived benefits of doing so are investigated. Amongst other things, we find that (i) the extent of employee participation varies significantly across firms; (ii) larger CRM campaigns tend to be managed centrally with relatively less employee participation than smaller ones and (iii) financial services firms are more likely to make CRM decisions centrally, with relatively less employee participation than retail services firms. (shrink)

In this paper I will present conceptions of state reduction and particle and/or system localization which render these subjects fully compatible with the general requirements of a relativistic, i.e. Lorentz invariant, quantum theory. The approach consists of a systematic generalization of the concepts of initial data assignment at definite times, initiation and completion of measurements at definite times, and dynamical evolution as time dependence, to the concepts of initial data assignment on arbitrary space-like hyperplanes, initiation and completion of measurements on (...) arbitrary space-like hyperplanes, and dynamical evolution as space-like hyperplane dependence, respectively. I also briefly discuss the superluminal propagation which emerges from the localization study and the manner in which causal anomalies are nevertheless avoided. (shrink)

It is difficult to generalize about ethical values in the Mahāyāna Buddhist tradition, let alone in Buddhist philosophy more generally. One author identifies seventeen distinct ethical approaches in the Mahāyāna scholarly traditions alone (i.e., not including various folk traditions).1 Nonetheless, in comparative studies in the history of ethics, there is increasing recognition that several different Buddhist traditions have stressed a foundational role for universalist altruism that was largely absent from ancient Greek eudaimonism and perhaps even absent-qua foundational-from most other premodern (...) traditions of moral reflection in the West, including much of the Christian tradition.2 In particular, ancient and .. (shrink)

This chapter is concerned with the representation of time and change in classical (i.e., non-quantum) physical theories. One of the main goals of the chapter is to attempt to clarify the nature and scope of the so-called problem of time: a knot of technical and interpretative problems that appear to stand in the way of attempts to quantize general relativity, and which have their roots in the general covariance of that theory. The most natural approach to these questions is via (...) a consideration of more clear cases. So much of the chapter is given over to a discussion of the representation of time and change in other, better understood theories, starting with the most straightforward cases and proceeding through a consideration of cases that lead up to the features of general relativity that are responsible for the problem of time. (shrink)

L'opera di Primo Levi presenta un caso straordinariamente ricco e in qualche modo enigmatico di intertestualità. Con questo volume si è cercato di tracciare i lineamenti di una mappa immaginaria, uno schema degli innesti, intertesti e trapianti che collegano l'opera leviana ai libri altrui.

This paper analyzes "ticking time bomb" scenarios in the discursive legitimation of torture and other coercive interrogation techniques. Judith Butler proposes a Foucauldian framework to suggest that Adminstration policies can be read as the irruption of sovereignty within governmentality. Rereading Foucault, I suggest that the policies could equally be understood as an exercise of governmentality, i.e., the subordination of juridical law to economy. I then propose as a reconciliation of these readings that time bomb scenarios serve rhetorically to make the (...) exercise of arbitrary power Butler identifies appear as an exercise of governmentality; sanitized of complications, coercive interrogation appears efficient. (shrink)

Psychology’s emphasis on empirical investigation has long benefited from conceptual developments taking place in its intellectual community, but also from cognate areas in Philosophy. This paper explores the implications for empirical psychology of a recent conceptual proposal advanced within the philosophy of perception by Bence Nanay. In particular, Nanay proposes that “pragmatic representations”, i.e., perceptual representations of the properties of objects necessary for the successful completion of actions, are the rightful target for a success semantics. A success semantics is, roughly (...) speaking, a theory of contents according to which the truth conditions of representations are to be identified with the success conditions of actions guided by the representations. The problem arises for Nanay’s proposal in that the empirical scrutiny of the contents of a pragmatic representation requires that one first ascertains their content, but it is not at all clear whether this could possibly be done given the non-linguistic character of pragmatic representations on the one hand, and the linguistic character of third-personal verbal data acquired through an heterophenomenological methodology on the other. This and other concerns raise worries about the empirical scrutability of Nanay’s proposal. (shrink)

Should we regard Jennifer Lackey’s ‘Creationist Teacher’ as understanding evolution, even though she does not, given her religious convictions, believe its central claims? We think this question raises a range of important and unexplored questions about the relationship between understanding, factivity and belief. Our aim will be to diagnose this case in a principled way, and in doing so, to make some progress toward appreciating what objectual understanding—i.e., understanding a subject matter or body of information—demands of us. Here is the (...) plan. After some ground clearing in §1, §2 outlines and motivates a plausible working model—moderate factivity—for characterising the sense in which objectual understanding should be regarded as factive. §3 shows how the datum that we can understand false theories can, despite initial suggestions to the contrary, be assimilated straightforwardly within the moderate factivity model. §4 highlights how the inverse kind of case to that explored in §3—viz., a variant of Lackey’s creationist teacher case—poses special problems for moderate factivity. With reference to recent work on moral understanding by Hills, §5 proposes a solution to the problem, and §6 attempts to diagnose why it is that we might originally have been led to draw the wrong conclusion. (shrink)

We show that the contemporary debate surrounding the question “What is the norm of assertion?” presupposes what we call the quantitative view, i.e. the view that this question is best answered by determining how much epistemic support is required to warrant assertion. We consider what Jennifer Lackey ( 2010 ) has called cases of isolated second-hand knowledge and show—beyond what Lackey has suggested herself—that these cases are best understood as ones where a certain type of understanding , rather than knowledge, (...) constitutes the required epistemic credential to warrant assertion. If we are right that understanding (and not just knowledge) is the epistemic norm for a restricted class of assertions, then this straightforwardly undercuts not only the widely supposed quantitative view, but also a more general presupposition concerning the universalisability of some norm governing assertion—the presumption (almost entirely unchallenged since Williamson’s 1996 paper) that any epistemic norm that governs some assertions should govern assertions—as a class of speech act—uniformly. (shrink)

ABSTRACT It is easy to think of consciousness as a medium, with two teams of philosophers disagreeing over whether the medium is transparent or translucent. G. E. Moore's “Refutation of Idealism” is still enlisted in defense of transparence, and Thomas Nagel's “What Is It Like to Be a Bat?” is still used to motivate translucency. I argue against both of these familiar interpretations of these articles and proceed to defend the very first response to Moore's article: James's insistence that consciousness, (...) construed as a transparent or translucent medium, just does not exist. Finally, and quite surprisingly, by refusing to treat consciousness as any sort of medium, James is able to account for how easy it is, and yet how difficult it is, to escape our insipid existence. (shrink)

Great technological advances in such areas as computer science, artificial intelligence, and robotics have brought the advent of artificially intelligent robots within our reach within the next century. Against this background, the interdisciplinary field of machine ethics is concerned with the vital issue of making robots “ethical” and examining the moral status of autonomous robots that are capable of moral reasoning and decision-making. The existence of such robots will deeply reshape our socio-political life. This paper focuses on whether such highly (...) advanced yet artificially intelligent beings will deserve moral protection once they become capable of moral reasoning and decision-making. I argue that we are obligated to grant them moral rights once they have become full ethical agents, i.e., subjects of morality. I present four related arguments in support of this claim and thereafter examine four main objections to the idea of ascribing moral rights to artificial intelligent robots. (shrink)

Bioconservative bioethicists (e.g., Kass, 2002, Human Dignity and Bioethics, 297–331, 2008; Sandel, 2007; Fukuyama, 2003) offer various kinds of philosophical arguments against cognitive enhancement—i.e., the use of medicine and technology to make ourselves “better than well” as opposed to merely treating pathologies. Two notable such bioconservative arguments appeal to ideas about (1) the value of achievement, and (2) authenticity. It is shown here that even if these arguments from achievement and authenticity cut ice against specifically pharmacologically driven cognitive enhancement, they (...) do not extend over to an increasingly viable form of technological cognitive enhancement – namely, cognitive enhancement via augmented reality. An important result is that AR-driven cognitive enhancement aimed at boosting performance in certain cognitive tasks might offer an interesting kind of “sweet spot” for proponents of cognitive enhancement, allowing us to pursue many of the goals of enhancement advocates without running into some of the most prominent objections from bioconservative philosophers. (shrink)

Plato: Symposium, translated by B. Jowett. Phaedo, translated by B. Jowett. Sophist, translated by B. Jowett.--Aristotle: De anima, translated by R. D. Hicks. Metaphysics (selections) translated by H. Tredennick. Nichomachean ethics (selections) translated by H. Rackham.--R. Descartes: Meditations, translated by E. S. Haldane and G. R. T. Ross.--G. Berkeley: Three dialogues between Hylas and Philonus.--D. Hume: Dialogues concerning natural religion.--I. Kant: Prolegomena to every future, translated by C. J. Friedrich. Metaphysical foundations of morals, translated by C. J. Friedrich.

It is often taken for granted that monitoring stands in some kind of tension with trusting (e.g., Hieronymi 2008; Wanderer and Townsend 2013; Nguyen forthcoming; McMyler 2011, Castelfranchi and Falcone 2000; Frey 1993; Dasgupta 1988, Litzky et al. 2006) — especially three-place trust (i.e., A trusts B to X), but sometimes also two-place trust (i.e., A trusts B, see, e.g., Baier 1986). Using a case study involving relationship breakdown, repair, and formation, I will argue there are some ways in which (...) monitoring can be conducive to two-place trust, and to instances of three-place trust that are likely to be repeated over time—especially when previously established two-place trust has broken down. The result, I hope, is not any kind of abandoning of the important idea that monitoring can undermine trust, but an appreciation of where the conflict between monitoring and trust doesn’t lie – one from which future work will hopefully be better positioned to illuminate where exactly the conflict is. (shrink)

It is often taken for granted that monitoring stands in some kind of tension with trusting (e.g., Hieronymi 2008; Wanderer and Townsend 2013; Nguyen forthcoming; McMyler 2011, Castelfranchi and Falcone 2000; Frey 1993; Dasgupta 1988, Litzky et al. 2006) — especially three-place trust (i.e., A trusts B to X), but sometimes also two-place trust (i.e., A trusts B, see, e.g., Baier 1986). Using a case study involving relationship breakdown, repair, and formation, I will argue there are some ways in which (...) monitoring can be conducive to two-place trust, and to instances of three-place trust that are likely to be repeated over time—especially when previously established two-place trust has broken down. The result, I hope, is not any kind of abandoning of the important idea that monitoring can undermine trust, but an appreciation of where the conflict between monitoring and trust doesn’t lie – one from which future work will hopefully be better positioned to illuminate where exactly the conflict is. (shrink)

I attempt to show that when someone is, E.G., Angry about something, The events or states that conjointly are causing him to be angry conform to a certain structure, And that from the causal structure underlying his anger it is possible to 'read out' what he is angry about. In this respect, And even in some of the details of the structure, My analysis of being angry about something resembles the belief-Want analysis of intentional action. The chief elements of the (...) causal structure I describe are a belief and an attitude so related in content as to constitute either a wish-Frustration (in the case of negative emotions) or a wish-Satisfaction (in the case of positive emotions). The analysis makes otiose, In those cases for which it is a correct analysis, The mysterious non-Causal relation between an emotion and its 'object' which is invoked by the majority of philosophers now writing on emotions. (shrink)

The problem of divine impassibility, i.e., of whether the divine nature in Christ could suffer, stands at the center of a debate regarding the nature of God and his relation to us. Whereas philosophical reasoning regarding the divine nature maintains that the divine is immutable and perfect in every respect, theological needs generated an ever-growing demand for a passionate God truly able to participate in the suffering of his creatures. Correlating with the different approaches of Thomas Aquinas and John Duns (...) Scotus, the paper develops an incarnation model that aims, on the one hand, to solve the dualistic problem between the divine and human natures, and on the other hand to make room for both impassible and passible elements in God, and so to make room within the patristic impassible model for genuine suffering in God. The discussion, though centered around Christ's im/passibility and passions, can easily be modified to approach the body-mind problem since the essence of the problems is the same. (shrink)

Consideration of the experimental activities carried out in one discipline, through the lens of another, can lead to novel insights. Here, we comment from a biological perspective upon experiments in quantum mechanics proposed by physicists that are likely to feasible in the near future. In these experiments, an entire living organism would be knowingly placed into a coherent quantum state for the first time, i.e. would be coerced into demonstrating quantum phenomena. The implications of the proposed experiment for a biologist (...) depend to an extent upon the outcomes. If successful, then the organism will have been temporarily in a state where it has an unmeasurable metabolism—not because a metabolic rate is undetectable, but because any attempt to measure it would automatically bring the organism out of the state. We argue that this would in essence represent a new category of cryptobiosis. Further, the organism would not necessarily retain all of the characteristics commonly attributed to living systems, unlike the currently known categories of cryptobiosis. If organisms can survive having previously been in a coherent state, then we must accept that living systems do not necessarily need to remain in a decoherent state at all times. This would be something new to biologists, even if it might seem trivial to physicists. It would have implications concerning the physical extremes organisms can tolerate, the search for extraterrestrial life, and our philosophical view of animation. (shrink)

An emerging line of research in bioethics questions whether enhanced love is less significant or valuable than otherwise, where "enhanced love" generally refers to cases where drugs (e.g., oxytocin, etc.) are relied on to maintain romantic relationships. Separate from these debates is a recent body of literature on the philosophy and psychology of "Virtual Reality (VR) dating," where romantic relationships are developed and sustained in a way that is mediated by VR. Interestingly, these discussions have proceeded largely independently from each (...) other. This article considers whether and to what extent philosophical arguments leveled against the value of enhanced love in the pharmacological case extend to cases where loving relationships are technologically mediated via VR rather than pharmacologically mediated. It will be argued that, while some worries about the pharmacological case do not extend over in a way that will be particularly problematic for VR, two (of the four arguments considered) are more prima facie serious. I conclude by suggesting why even these stronger argument strategies are not insurmountable and, thus, that there is reason to be cautiously optimistic that VR-mediated love can largely withstand variations on the bioconservative critiques that target pharmacologically enhanced love. (shrink)

Moral enhancement proposals struggle to be both plausible and ethically defensible while nevertheless interestingly distinct from both cognitive enhancement as well as (mere) moral education. Brian Earp (_Royal Institute of Philosophy Supplement_ 83:415–439, 12 ) suggests that a promising middle ground lies in focusing on the (suitably qualified) use of psychedelics as _adjuncts_ to moral development. But what would such an adjunctive use of psychedelics look like in practice? In this paper, I draw on literature from three areas where techniques (...) for moral development have been discussed: psychotherapy (e.g., Overholser 2010; Burns 1980) education (e.g., Uhl and Lütge, 2018), and AI-assisted enhancement (e.g., Lara and Deckers, _Neuroethics_ 13(3):275–287, 17 ) in order to propose more concrete ways in which to use psychedelics as adjuncts to moral development. It is shown that in each of these areas, we can see that _trusting_ relationships (e.g., Baier 1986; Hawley 2019) between the facilitator and the agent will very plausibly maximize the success of this type of moral enhancement. Finally, I appeal to literature on informed consent for use of psychedelics (e.g., Smith and Sisti, _Journal of Medical Ethics_, 22 ; Johnson et al., _The Journal of Psychopharmacology_ 22(6):603–20, 23 ) and on the therapeutic relationship in psychotherapy (e.g., Dryden and Reeves 2013; Horvath et al. 2011) to outline concrete suggestions for facilitating dimensions of trust most likely to maximize the benefits of (adjunctive) psychedelic moral enhancement. The result is a newly detailed practical proposal for how we might best facilitate moral enhancement by using drugs as adjuncts to moral development. (shrink)

PovertyPoverty is a serious threat for human beings and their well-beingWell-being. People are simply unable to live a good life when they are faced with severe problems, e.g., bad education, poor housing, poor sanitationSanitation, poor hygiene, or malnourishment. However, one of the most urgent problems with regard to poverty is badHealth/ healthcare, right toaccess access to primary health careGlobal healthcare and the allocation of health care resources for millions of people around the world. These people are deprived of human flourishing, (...) and life is for them, in general, “solitary, poor, nasty, brutish, and short.” In this chapter, I present an ethical argument that shows that people have a moral right to primary health carePrimary health care, and that wealthy developed countries are morally obligated to help the needy. Primary health care, and hence access to it is, as I will argue, a global public goodGlobal public good that is protected by human dignity and the human rightHuman rights of protection from unwarranted bodily harmHarm. (shrink)

Sleep strengthens memories by repeatedly reactivating associated neuron ensembles. Our studies show that although long-term memory for a medium number of word-pairs benefits from sleep, a large number does not. This suggests an upper limit to the amount of information that has access to sleep-dependent declarative memory consolidation, which is possibly linked to the availability of reactivation opportunities. Due to competing processes of global forgetting that are active during sleep, we hypothesized that even larger amounts of information would enhance the (...) proportion of information that is actively forgotten during sleep. In the present study, we aimed to induce such forgetting by challenging the sleeping brain with vast amounts of to be remembered information. For this, 78 participants learned a very large number of 640 word-pairs interspersed with periods of quiet awake rest over the course of an entire day and then either slept or stayed awake during the night. Recall was tested after another night of regular sleep. Results revealed comparable retention rates between the sleep and wake groups. Although this null-effect can be reconciled with the concept of limited capacities available for sleep-dependent consolidation, it contradicts our hypothesis that sleep would increase forgetting compared to the wake group. Additional exploratory analyses relying on equivalence testing and Bayesian statistics reveal that there is evidence against sleep having a detrimental effect on the retention of declarative memory at high information loads. We argue that forgetting occurs in both wake and sleep states through different mechanisms, i.e., through increased interference and through global synaptic downscaling, respectively. Both of these processes might scale similarly with information load. (shrink)

In this article, I question the general idea that inclusive education — i.e., to teach all students in one class — is a moral human right. The following discussion shows that the widespread view in disability studies that there is a moral human right to inclusive education can be reasonably called into question by virtue of the proposed counter arguments, but without denying that inclusive education is of utmost importance. Practically speaking, the legal human right to inclusive education is of (...) great practical value for impaired students, and for their basic right to be free from discrimination in education, since their concern thereby gains great legal and moral force. But, theoretically speaking, this particular human right lacks an attainable consensus concerning proper moral justification. (shrink)

Robert M. Adams has written a fairly short book, but into it he has packed a lifetime of rigorous analytic thought, and, what is rarer, deep insight into the nature of things. The book expands and recasts Gifford Lectures that Adams delivered in 1999, as well as other lectures and papers, and though it addresses difficult issues, Adams's clear style, retaining the informality of lectures, considerably eases the task of the reader; and the book is not without an occasional touch (...) of humour, e.g. ‘As metaphysicians we may wish to assign a certain oomph to one side or the other in such lawgoverned relations; but it is not clear that the concept of oomph is at home in fundamental physics’ (p. 12).I cannot cover all the many and various topics in the book, but I shall endeavour in what follows to present a central thread of argument in it, the distinction between what is and what is in itself (the centrality of which is indicated by its presence in the book's title) and to show how this distinction leads to the theistic and idealist metaphysics to which the author is inclined. (shrink)

Importance Informed consent is essential to ethical, rigorous research and is important to recruitment and retention in cancer trials.Objective To examine cancer clinical trial (CCT) participants’ perceptions of informed consent processes and variations in perceptions by cancer type.Design and Setting and Participants Cross-sectional survey from mixed-methods study at National Cancer Institute–designated Northeast comprehensive cancer center. Open-ended and forced-choice items addressed: (1) enrollment and informed consent experiences and (2) decision-making processes, including risk-benefit assessment. Eligibility: CCT participant with gastro-intestinal or genitourinary, hematologic-lymphatic (...) malignancies, lung cancer, and breast or gynecological cancer (N = 334).Main Outcome Measures Percentages satisfied with consent process and information provided; and assessing participation’s perceptions of risks/benefits. Multivariable logistic or ordinal regression examined differences by cancer type.Results Most patient-participants felt well informed by the consent process (more than 90% overall and by cancer type) and. most (87.4%) reported that the consent form provided all the information they wanted, although nearly half (44.8%) reported that they read the form somewhat carefully or less. More than half (57.9%) said that talking to research staff (i.e., the consent process) had a greater impact on participation decisions than reading the consent form (2.1%). A third (31.1%) were very sure of joining in research studies before the informed consent process (almost half of lung cancer patients did—47.1%). Most patients personally assessed the risks and benefits before consenting. However, trust in physicians played an important role in the decision to enroll in CCT.Conclusions and Relevance Cancer patients rely less on written features of the informed consent process than on information obtained from the research staff and their own physicians. Research should focus on information and communication strategies that support informed consent from referring physicians, researchers, and others to improve patient risk-benefit assessment and decision-making. (shrink)

Apoptosis is now widely recognized as a common form of cell death and represents a mechanism of cell clearance in many physiological situations where deletion of cells is required. Peptide growth factors, initially characterised as stimulators of cell proliferation, have now been shown to inhibit death in many cell types. Deprivation of growth factors leads to the induction of apoptosis, i.e. condensation of chromatin and degradation in oligonucleosomesized fragments, formation of plasma and nuclear membrane blebs and cell fragmentation into apoptotic (...) bodies which can be taken up by neighbouring cells. Here we discuss the mechanism(;s) by which growth factors may inhibit apoptosis. (shrink)

No crucial experiment demonstrates that four hue categories are needed to describe color appearance. Instead, converging lines of evidence suggest that the terms red, yellow, green, and blue are sufficient and precise enough for deriving color discrimination functions and for a useful model constraining relations between color appearance and neuronal responses. Such a model need not be based on linguistic universals. Until something better is available, this holds.

В книгу вошли высказывания об искусстве и воображении философов, эстетиков, психологов, искусствоведов и мастеров искусства.

Издание содержит: хрестоматия; философы; психологи; литературоведы, искусствоведы; мастер изобразительного искусства и др.

Вниманию читателя предлагаются статьи, посвященные мало исследованным проблемам логики (и психологии) художественного творчества, в частности в работах М. Бахтина. Книга содержит также хрестоматию "Искусство и логика" и предметный указатель.

The essay explores the meaning and implications of Milbank's claim that the post‐Kantian presuppositions of modern theology must be eradicated. After defining and locating the post‐Kantian element in the context of Milbank's broader concerns, the essay employs a comparison between Milbank and Barth to draw out the differences between radical orthodoxy and neo‐orthodoxy with respect to the Kantian ideal of “mediation” between theology and culture. The essay concludes with comparisons of Milbank's metanarrative concerning “modern” thought with those offered by Hans (...) Blumenberg and James Edwards. The effect is not only to suggest the apparent arbitrariness of Milbank's account, but also to indicate the evident futility of arguing with Milbank's theological position on the basis of alternative accounts of the post‐Kantian tradition. (shrink)

The prospects for realistic interpretation of the nature of initial mathematical truths and objects are considered in the article. The arguments of realism, reasons impeding its recognition among philosophers of mathematics as well as the ways to eliminate these reasons are discussed. It is proven that the absence of acceptable ontological interpretation of mathematical realism is the main obstacle to its recognition. This paper explicates the introductory positions of this interpretation and presents a realistic interpretation of the arithmetical component of (...) mathematics. In summary, we should like to note that such constructions, as it is shown to us, ought to bring the direct use not only for the philosophical foundation of mathematics but for mathematics itself. In the justification of the author’s conclusions based on the works of famous mathematicians of the twentieth century, interpreting their findings in a broad historical and philosophical context. To illustrate his point, the author gives examples of arithmetic and geometry - both Euclidean and non-Euclidean. (shrink)