Each year, over 200 million people are infected with the malaria parasite, nearly half a million of whom succumb to the disease. Emerging genetic technologies could, in theory, eliminate the burden of malaria throughout the world by intentionally eradicating the mosquitoes that transmit the disease. In this paper, we offer an ethical examination of the intentional eradication of Anopheles gambiae, the main malaria vector of sub-Saharan Africa. In our evaluation, we focus on two main considerations: the benefit of alleviating the (...) malaria burden, and the loss of value that would accompany the eradication of the species. We outline a typology of the different ways in which species are valued or could be valuable, then use that typology to appraise the value of the species in question. We argue that Anopheles gambiae has minor (and redundant) instrumental value, little final subjective value and no objective final value. (shrink)

Highly idealized models, such as the Hawk-Dove game, are pervasive in biological theorizing. We argue that the process and motivation that leads to the introduction of various idealizations into these models is not adequately captured by Michael Weisberg’s taxonomy of three kinds of idealization. Consequently, a fourth kind of idealization is required, which we call hypothetical pattern idealization. This kind of idealization is used to construct models that aim to be explanatory but do not aim to be explanations.

Within the modeling literature, there is often an implicit assumption about the relationship between a given model and a scientific explanation. The goal of this article is to provide a unified framework with which to analyze the myriad relationships between a model and an explanation. Our framework distinguishes two fundamental kinds of relationships. The first is metaphysical, where the model is identified as an explanation or as a partial explanation. The second is epistemological, where the model produces understanding that is (...) related to the explanation of interest. Our analysis reveals that the epistemological relationships are not always dependent on the metaphysical relationships, contrary to what has been assumed by many philosophers of science. Moreover, we identify several importantly different ways that scientific models instantiate these relationships. We argue that our framework provides novel insights concerning the nature of models, explanation, idealization, and understanding. (shrink)

Part of what makes the environment valuable is its autonomy. There are some who think that any human influence on an environment is necessarily autonomy-compromising because it is a form of human control. In this article, I will assume human influence on the environment necessarily undermines autonomy. However, I will argue, even given this assumption, it is still possible for the intervention to enable autonomy in the long run. My focus is on genetic intervention into organisms, because some might think (...) human influence in these cases cannot dissipate. I argue this is mistaken and, borrowing a concept from botany, I argue genes, even genes inserted into a genome by humans, can “naturalize.” Furthermore, they can function in ways that are autonomy-enabling to the individual and to the system to which the organism belongs. (shrink)

Can one still have understanding in situations that involve the kind of epistemic luck that undermines knowledge? Kvanvig (The value of knowledge and the pursuit of understanding, 2003; in: Haddock A, Miller A, Pritchard D (eds) Epistemic value, 2009a; in: Haddock A, Miller A, Pritchard D (eds) Epistemic value, 2009b) says yes, Prichard (Grazer Philos Stud 77:325–339, 2008; in: O’Hear A (ed) Epistemology, 2009; in: Pritchard D, Millar A, Haddock A (eds) The nature and value of knowledge: three investigations, 2010) (...) say sometimes, DePaul and Grimm (Philos Phenomenol Res 74:498–514, 2007) and Grimm (Br J Philos Sci 57:515–535, 2006; in: Bernecker S, Pritchard D (eds) The Routledge companion to epistemology, 2011), Kvanvig’s critics, say no. The cases put forth by Kvanvig’s critics share a common feature, which seems to drive the intuition that understanding can’t be lucky: the fact that the information that makes up the individual’s understanding comes exclusively from a bad source. I formulate a case that lacks this feature, drawing on the fact that understanding produced from scientific inquiry is often produced by collaboration. I argue that my case provides good evidence that understanding is not a species of knowledge. (shrink)

Many environmental ethicists think evolutionary processes are good or, put differently, that they are morally valuable. Furthermore, many claim this value can be compromised when humans disrupt or cause a break in these processes. In this paper, I argue this account is mistaken. Evolution is not good. Furthermore, evolution cannot be “broken” by mere human involvement. There is no preordained trajectory in evolution; randomness, genetic drift, and historical contingency influence all evolutionary histories. Additionally, to think humans necessarily undermine so-called “natural” (...) processes and turn them artificial is to ignore Vogel (2011, 2015), and insist on pre-Darwinian dualism. There is no morally meaningful distinction between natural selection and artificial selection; they are both simply selection. Furthermore, animals shape their own evolutionary trajectories, their progenies’, and those of other organisms through their intentions and choices—as is illustrated in the theory of niche construction. Human involvement in evolutionary processes does not “break” them nor does it necessarily reduce the value of the end products of those processes. (shrink)

We argue that the de-extinction of the mammoth cannot be ethically grounded by duties to the extinct mammoth, to ecosystem health or to individual organisms in ecosystems missing the mammoth. However, the action can be shown to be morally permissible via the goods it will afford humans, including advances in scientific knowledge, valuable experiences of awe and pleasure, and perhaps improvements to our moral character or behaviour—if and only if suffering is minimal. Finally, we call for empirical research into how (...) the possibility of the technology affects our behaviour or our character to help the debate transcend duelling intuitions. (shrink)

Some conservation biologists invoke the concept of ‘genetic integrity,’ which they generally assume is a good worth preserving without explicit justification. We examine the question of whether or not there is a prima facie duty to preserve genetic integrity in conservation biology. We examine several possible justifications for the potential duty found in the conservation biology literature. We argue, contra a dominant trend of thought in conservation biology, that there is no prima facie duty to preserve genetic integrity and that (...) any moral obligation to preserve genetic integrity in specific cases is merely derivative of other possible duties. (shrink)

Shapiro and Sober claim that Walsh, Ariew, Lewens, and Matthen give a mistaken, a priori defense of natural selection and drift as epiphenomenal. Contrary to Shapiro and Sober’s claims, we first argue that WALM’s explanatory doctrine does not require a defense of epiphenomenalism. We then defend WALM’s explanatory doctrine by arguing that the explanations provided by the modern genetical theory of natural selection are ‘autonomous-statistical explanations’ analogous to Galton’s explanation of reversion to mediocrity and an explanation of the diffusion ofgases. (...) We then argue that whereas Sober’s theory of forces is an adequate description of Darwin’s theory, WALM’s explanatory doctrine is required to understand how themodern genetical theory of natural selection explains large-scale statistical regularities. 1 Introduction2 Shapiro and Sober’s ‘Epiphenomenalism Do’s and Don’ts’3 WALM’s Explanatory Doctrine4 Galton’s Autonomous-Statistical Explanation5 A Second Example: The Statistical Explanation of the Diffusion of Gases6 Distinguishing Two Theories of Evolution by Natural Selection7 A Possible Objection: Are Statistical Laws Sufficient for Explanation?8 Conclusion. (shrink)

Highly idealized models, such as the Hawk-Dove game, are pervasive in biological theorizing. We argue that the process and motivation that leads to the introduction of various idealizations into these models is not adequately captured by Michael Weisberg’s taxonomy of three kinds of idealization. Consequently, a fourth kind of idealization is required, which we call hypothetical pattern idealization. This kind of idealization is used to construct models that aim to be explanatory but do not aim to be explanations.

In this article I argue that humans have a pro tanto duty to cognitively enhance some animals threatened with extinction. I will use as a case study a particular set of animals: smaller Australian marsupials. Many of these animals are on the brink of extinction thanks to the introduction of the fox and the domestic cat to the continent of Australia. Ecologists conjecture that these marsupials do not have the behavioural flexibility to cope with these introduced predators. By introducing predators, (...) humans performed a wrong action because it led to the extinction of species and continues to threaten many marsupials species such as woylies, Gilbert's potoroos, numbats and mountain pygmy possums. This wrong action gives rise to an obligation to intervene to prevent further species loss. Traditional means of conservation do not seem sufficient to address this obligation; therefore, there is a duty to cognitively enhance these creatures as soon as the technology is sufficiently researched and safe. (shrink)

In this paper, we argue that rather than exclusively focusing on trying to determine if an idealized model fits a particular account of scientific explanation, philosophers of science should also work on directly analyzing various explanatory schemas that reveal the steps and justification involved in scientists’ use of highly idealized models to formulate explanations. We develop our alternative methodology by analyzing historically important cases of idealized statistical modeling that use a three-step explanatory schema involving idealization, mathematical operation, and explanatory interpretation.

Game theory has played a critical role in elucidating the evolutionary origins of social behavior. Sober and Wilson model altruism as a prisoner's dilemma and claim that this model indicates that altruism arose from group selection pressures. Sober and Wilson also suggest that the prisoner's dilemma model can be used to characterize punishment; hence, punishment too originated from group selection pressures. However, empirical evidence suggests that a group selection model of the origins of altruistic punishment may be insufficient. I argue (...) that examining dominance hierarchies and coalition formation in chimpanzee societies suggests that the origins of altruistic punishment may be best captured by individual selection models. I suggest that this shows the necessity of coupling of game-theoretic models with a conception of what our actual social structure may have been like to best model the origins of our own behavior. ‡I would like to thank Zachary Ernst and Emma Marris for their many helpful comments which greatly improved this paper. †To contact the author, please write to: Department of Philosophy, University of Maryland, Skinner Building, College Park, MD 20742; e-mail: [email protected]. (shrink)

1. Traditional conservation biology has focused on two goals: preserving and protecting biodiversity and ecosystem integrity (e.g., Noss, 2001; Soulé, 1985). When species go extinct, this reduces b...

1. In this paper I will explore the moral permissibility of a possible genetic intervention to save the ʻōhiʻa lehua tree from fungal pathogens from two different metaphysical perspectives: western...

The concept of explanation is central to scientific practice. However, scientists explain phenomena in very different ways. That is, there are many different kinds of explanation; e.g. causal, mechanistic, statistical, or equilibrium explanations. In light of the myriad kinds of explanation identified in the literature, most philosophers of science have adopted some kind of explanatory pluralism. While pluralism about explanation seems plausible, it faces a dilemma Explanation beyond causation, Oxford University Press, Oxford, pp 39–56, 2018). Either there is nothing that (...) unifies all instances of scientific explanation that makes them count as explanations, or there is some set of unifying features, which seems incompatible with explanatory pluralism. Different philosophers have adopted different horns of this dilemma. Some argue that no unified account of explanation is possible. Others suggest that there is a set of necessary features that can unify all explanations under a single account Explanation beyond causation, Oxford University Press, Oxford, pp 74–95, 2018; Strevens in Depth: an account of scientific explanation, Harvard University Press, Cambridge, 2008). In this paper, we argue that none of the features identified by existing accounts of explanation are necessary for all explanations. However, we argue that a unified account can still be provided that accommodates pluralism. This can be accomplished, we argue, by reconceiving of scientific explanation as a cluster concept: there are multiple subsets of features that are sufficient for providing an explanation, but no single feature is necessary for all explanations. Reconceiving of explanation as a cluster concept not only accounts for the diversity of kinds of explanations, but also accounts for the widespread disagreement in the explanation literature and enables explanatory pluralism to avoid Pincock’s dilemma. (shrink)

What sort of epistemic positions are compatible with inquiries driven by interrogative attitudes like wonder and puzzlement? The ignorance norm provides a partial answer: interrogative attitudes directed at a particular question are never compatible with knowledge of the question’s answer. But some are tempted to think that interrogative attitudes are incompatible with weaker positions like belief as well. This paper defends that the ignorance norm is exhaustive. All epistemic positions weaker than knowledge directed at the answer to a question are (...) compatible with having an interrogative attitude towards that question. We offer two arguments for this conclusion. The first is based on considerations about the role of hedging in inquiry. The second is conditional on considerations related to the aim of inquiry as a goal-directed activity. (shrink)

Viruses are major drivers of global biogeochemistry and the etiological agents of many diseases. They are also the winners in the game of life: there are more viruses on the planet than cellular organisms and they encode most of the genetic diversity on the planet. In fact, it is reasonable to view life as a viral incubator. Nevertheless, most ecological and evolutionary theories were developed, and continue to be developed, without considering the virosphere. This means these theories need to be (...) to reinterpreted in light of viral knowledge or we need to develop new theory from the viral point-of-view. Here we briefly introduce our viral planet and then address a major outstanding question in biology: why is most of life viral? A key insight is that during an infection cycle the original virus is completely broken down and only the associated information is passed on to the next generation. This is different for cellular organisms, which must pass on some physical part of themselves from generation to generation. Based on this premise, it is proposed that the thermodynamic consequences of physical information (e.g., Landauer’s principle) are observed in natural viral populations. This link between physical and genetic information is then used to develop the Viral Information Hypothesis, which states that genetic information replicates itself to the detriment of system energy efficiency (i.e., is viral in nature). Finally, we show how viral information can be tested, and illustrate how this novel view can explain existing ecological and evolutionary theories from more fundamental principles. (shrink)

A recent fMRI study by Webb et al. (Cortical networks involved in visual awareness independent of visual attention, Proc Natl Acad Sci U S A 2016;113:13923–28) proposes a new method for finding the neural correlates of awareness by matching atten- tion across awareness conditions. The experimental design, however, seems at odds with known features of attention. We highlight logical and methodological points that are critical when trying to disentangle attention and awareness.

BackgroundThe significant increase of digital collaboration, driven by the current COVID-19 pandemic, is resulting in changes in working conditions and associated changes in the stress-strain perception of employees. Due to the evident leadership influence on employees' health and well-being in traditional work settings, there is a need to investigate leadership in virtual remote work contexts as well. The objective of this scoping review was to assess the extent and type of evidence concerning virtual leadership in relation to employees' mental health, (...) job satisfaction and perceptions of isolation.MethodA search was undertaken in five databases, PubMed, Cochrane Library, PsycINFO, PSYNDEX and Web of Science, as well as reference lists of included articles on 9th February 2021 and an update on 28th September 2021. The search strategy was limited to English, German and French language, peer reviewed journal articles published from January 2000 onwards. This scoping review was conducted in accordance with the JBI methodology for scoping reviews. The methodological quality of the included studies was assessed using the JBI critical appraisal tools. A narrative synthesis was conducted.ResultsNineteen studies met the eligibility criteria for this review. Overarching review findings suggested a positive link between virtual leadership and well-being, job satisfaction, and a negative link to psychological strain, stress and perceptions of isolation of digitally collaborating employees.ConclusionsBy mapping the available evidence on virtual leadership in relation to health and work-related employee outcomes, the review identified many research gaps in terms of content and methodology. Due to limited data, causal relationships were not derived. Future research is needed to examine the complex cause-and-effect relationships of virtual leadership in more detail. (shrink)

Sociopolitical philosophies such as feminism, postcolonialism, and environmentalism can interact with traditional African cultural practices in dynamic and complex ways. This paper employs Val Plumwood's ecofeminist deconstruction of dualism to analyze the relationship between traditional and modern culture in postcolonial African literature, with a focus on the practice of bride price as depicted in the 1974 play, The Challenge of Fende by Cameroonian author Victor Musinga.

We investigate the common development of children’s ability to “look back in time” and to “look into the future” . Experiment 1 with 59 children 5 to 8.5 years old showed mental rotation, as a measure of prospection, explaining specific variance of free recall, as a measure of episodic remembering when controlled for cued recall. Experiment 2 with 31 children from 5 to 6.5 years measured episodic remembering with recall of visually experienced events when controlling for recall of indirectly conveyed (...) events . Quite unexpectedly rotators were markedly worse on indirect items than non-rotators. We speculate that with the ability to rotate children switch from knowledge retrieval to episodic remembering, which maintains success for experienced events but has detrimental effects for indirect information. (shrink)

Multilevel research strategies characterize contemporary molecular inquiry into biological systems. We outline conceptual, methodological, and explanatory dimensions of these multilevel strategies in microbial ecology, systems biology, protein research, and developmental biology. This review of emerging lines of inquiry in these fields suggests that multilevel research in molecular life sciences has significant implications for philosophical understandings of explanation, modeling, and representation.

Yasha Rohwer and Emma Marris argue there is no prima facie duty to preserve genetic integrity; they contend, rather, that preserving the integrity of specific genomes is only a mean...

Yasha Rohwer and Emma Marris argue that we do not have a prima facie duty to preserve the genetic integrity of species. Rohwer and Marris take the duty to preserve genetic integrity as being equal...

In their article Yasha Rohwer and Emma Marris argue that there is no underived prima facie obligation to preserve genetic integrity. It is clearly demonstrated that conservation bi...

The phenomenon of regression toward the mean is notoriously liable to be overlooked or misunderstood; regression fallacies are easy to commit. But even when regression phenomena are duly recognized, it remains perplexing how they can feature in explanations. This article develops a philosophical account of regression explanations as “statistically autonomous” explanations that cannot be deepened by adducing details about causal histories, even if the explananda as such are embedded in the causal structure of the world. That regression explanations have statistical (...) autonomy was first suggested by Ian Hacking and has recently been defended and elaborated by André Ariew, Yasha Rohwer, and Collin Rice. However, I will argue that these analyses fail to capture what regression’s statistical autonomy consists in and how it sets regression explanations apart from other kinds of explanation. The alternative account I develop also shows what is amiss with a recent denial of regression’s statistical autonomy. Marc Lange has argued that facts that can be explained as regression phenomena can in principle also be explained by citing a conjunction of causal histories. The account of regression explanation developed here shows that his argument is based on a misunderstanding of the nature of statistical autonomy. (shrink)

In this essay, I call into question Yasha Rohwer and Emma Marris’s attack on what they see as a dominant view in conservation biology: namely, that there is a prima facie moral duty to preserve gen...

Rohwer & Marris claim that “many conservation biologists” believe that there is a prima facie duty to preserve the genetic integrity of species. (A prima facie duty is a necessary pro tanto moral reason.) They describe three possible arguments for that belief and reject them all. They conclude that the biologists they cite are mistaken, and that there is no such duty: duties to preserve genetic integrity are merely instrumental: we ought act to preserve genetic integrity only because doing (...) so is required by some other duty, such as the duty to preserve taxonomic biodiversity, or the duty to preserve the reproductive fitness of existing species. In permitting for instance the introgression of cattle genes into the genome of Bison bison we therefore do not necessarily fail in any respect ethically. I criticize the paper on three fronts. (shrink)

Rohwer and Marris (2015) question the existence of a prima facie duty to preserve genetic integrity leaving open the question of what we should preserve. Many of the arguments used to justify their position could set the platform to defend a duty to preserve the diversity of both wild and domesticated species. In times where agricultural land covers a third of world’s land area and major efforts are undertaken to green urban areas a defense of biodiversity could benefit hugely (...) by intelligently incorporating human-induced diversification. It still remains critical to assess in how far new introductions compensate for losses and here the insights of those defending genetic integrity are an important tool. By acknowledging the added value of human-induced biodiversity we could slow down massive extinction of domesticated and semi-wild varieties by giving these a greater space in human-made environments. (shrink)

Rohwer and Marris’s exploration of grounds for a prima facie duty to preserve the genetic integrity of wild species makes two important contributions to the environmental ethics literature. While n...