Co‐option of the eye developmental gene regulatory network may have led to the appearance of novel functional traits on the wings of flies and butterflies. The first trait is a recently described wing organ in a species of extinct midge resembling the outer layers of the midge's own compound eye. The second trait is red pigment patches on Heliconius butterfly wings connected to the expression of an eye selector gene, optix. These examples, as well as others, are discussed regarding the (...) type of empirical evidence and burden of proof that have been used to infer gene network co‐option underlying the origin of novel traits. A conceptual framework describing increasing confidence in inference of network co‐option is proposed. Novel research directions to facilitate inference of network co‐option are also highlighted, especially in cases where the pre‐existent and novel traits do not resemble each other. (shrink)

Co‐option of the eye developmental gene regulatory network may have led to the appearance of novel functional traits on the wings of flies and butterflies. The first trait is a recently described wing organ in a species of extinct midge resembling the outer layers of the midge's own compound eye. The second trait is red pigment patches on Heliconius butterfly wings connected to the expression of an eye selector gene, optix. These examples, as well as others, are discussed regarding the (...) type of empirical evidence and burden of proof that have been used to infer gene network co‐option underlying the origin of novel traits. A conceptual framework describing increasing confidence in inference of network co‐option is proposed. Novel research directions to facilitate inference of network co‐option are also highlighted, especially in cases where the pre‐existent and novel traits do not resemble each other. (shrink)

Serial homology is widespread in organismal design, but the origin and individuation of these repeated structures appears to differ with the different types of serial homologues, and remains an intriguing and exciting topic of research. Here I focus on the evolution of the serially repeated eyespots that decorate the margin of the wings of nymphalid butterflies. In this system, unresolved questions relate to the evolutionary steps that lead to the appearance of these serial homologues and how their separate identities evolved. (...) I present and discuss two alternative hypotheses. The first proposes that eyespots first appeared as a row of undifferentiated repeated modules, one per wing compartment, that later become individuated. This individuation allowed eyespots to appear and disappear from specific wing compartments and also allowed eyespots to acquire different morphologies. The second hypothesis proposes that eyespots first appeared as individuated single units, or groups of units, that over evolutionary time were co‐opted into new compartments on the wing. I discuss the merits of each of these alternate hypotheses by finding analogies to other systems and propose research avenues for addressing these issues in the future. BioEssays 30:358–366, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

In this paper we describe a test for Nijhout's hypothesis that the eyespot patterns on butterfly wings are the result of a threshold reaction of the epidermal cells to a concentration gradient of a diffusing degradable morphogen produced by focal cells at the centre of the future eyespot. The wings of the nymphalid butterfly, Bicyclus anynana, have a series of eyespots, each composed of a white pupil, a black disc and a gold outer ring. In earlier extirpation and transplantation experiments (...) it has been established that these eyespots are indeed organised around groups of signalling cells active during the first hours of pupal development. If these cells were to supply the positional information for eyespot formation in accordance with Nijhout's diffusion-degradation gradient model, then, when two foci are close together, the signals should sum, and this effect should be apparent in the detailed shape of the resulting pigment pattern. We give an equation for the form of the contours that would be obtained in this manner. We use this to test the morphogen gradient hypothesis on measurements of the outlines of fused eyespots obtained either by grafting focal cells close together, or by using a mutation that produces adjacent fused eyespots. The contours of the fused patterns were found to satisfy our equation, thus corroborating Nijhout's hypothesis to the extent possible with this particular type of experiment. (shrink)

One of the central but yet unresolved problems in evolutionary biology concerns the origin of novel complex traits. One hypothesis is that complex traits derive from pre‐existing gene regulatory networks (GRNs) reused and modified to specify a novel trait somewhere else in the body. This simple explanation encounters problems when the novel trait that emerges in a body is in a region that is known to harbor a latent or repressed trait that has been silent for millions of years. Is (...) the novel trait merely a re‐emerged de‐repressed trait or a truly novel trait that emerged via a novel deployment of an old GRN? A couple of new studies sided on opposite sides of this question when investigating the origin of horns in dung beetles and helmets in treehoppers that develop in the first thoracic segment (T1) of their bodies, a segment known to harbor a pair of repressed/modified wings in close relatives. Here, I point to some key limitations of the experimental approaches used and highlight additional experiments that could be done in future to resolve the developmental origin of these and other traits. (shrink)

The differentiation of male and female characteristics in vertebrates and insects has long been thought to proceed via different mechanisms. Traditionally, vertebrate sexual development was thought to occur in two phases: a primary and a secondary phase, the primary phase involving the differentiation of the gonads, and the secondary phase involving the differentiation of other sexual traits via the influence of sex hormones secreted by the gonads. In contrast, insect sexual development was thought to depend exclusively on cell‐autonomous expression of (...) sex‐specific genes. Recently, however, new evidence indicates that both vertebrates and insects rely on sex hormones as well as cell‐autonomous mechanisms to develop sexual traits. Collectively, these new data challenge the traditional vertebrate definitions of primary and secondary sexual development, call for a redefinition of these terms, and indicate the need for research aimed at explaining the relative dependence on cell‐autonomous versus hormonally guided sexual development in animals. (shrink)

The particular fascination of butterfly wings for developmental biologists (and others) lies in their spectacular array of colour patterns. The evolutionary and developmental relationships between these patterns have been analysed and we know something of the cell interactions involved in their formation(1). Now butterfly homologues of Drosophila wing‐patterning genes have been identified, and their expression patterns offer the first clues to the molecular mechanisms which specify wing colour patterns(2).

Brazilian educator, Paulo Freire, best known for his work Pedagogy of the Oppressed, challenged education plans that contributed to the marginalization of minorities and the poor. Freire believed that education should be used for liberation by helping learners reflect on their experiences historically, giving immediate reality to issues of racism, sexism, and the exploitation of workers. Known as one of the most influential theoretical innovators of the twentieth century, his views have left a significant mark on progressive thinkers about education (...) and liberation. Reinventing Paulo Freire is an homage to him by protégé Antonia Darder. Here, she explores the legacy of Freire, interviews eight former students who studied him-- now teachers themselves, and reflects on the teaching practice as demonstrated by Freire himself. The interviews take the form of first person narratives; the epilogue consists simply of a letter and a poem. (shrink)

Antonia Lolordo presents an original interpretation of John Locke's metaphysics of moral agency, in which to be a moral agent is simply to be free, rational, and a person.

In the final pages of Chapter V of Afro-Brazilian Religions Roger Bastide sees, at a given moment in the socio-religious evolution of Brazil, a process of social disorganization which in its extent affects not only blacks but also poor white nationals and stranded immigrants.* As generator of a “ social marginalization,” this process could only be the passage through “a moment of transition” characterized by “the exaggerated speed of change in the country.” According to Bastide, an “organic period” follows: with (...) the “proletarization of the blacks, the assimilation of the immigrants, the general rise in the standard of living of the masses, other phenomena of cultural and social reintegration will appear.” On the religious level the “spiritism of umbanda“ is the expression of this new phase. (shrink)

Background Euthanasia is a controversial practice in many countries. Since Spain’s Euthanasia Law came into effect on March 24, 2021, healthcare providers have faced a new challenge since they must inform patients, provide care, accompany them, and implement the law. It also represents a new stumbling block at universities, which must adapt to regulatory changes and educate future professionals accordingly. Little is known about the attitude of nursing students in Spain toward euthanasia since this law was implemented. Objective This study (...) aims to answer the following research questions: What is the attitude of nursing students toward euthanasia? What factors influence this attitude? Research design A cross-sectional study was conducted using an online questionnaire. Participants and research context The study population comprised all nursing students at a public university in Barcelona ( n = 444), Spain, during the 2022–2023 academic year. The validated Spanish version of the Euthanasia Attitude Scale was employed. A bivariate analysis was performed. Ethical considerations The university Ethics Committee (CEEAH 6247) approved this study. All participating students signed an informed consent form. Participation was voluntary, and data anonymity and confidentiality were guaranteed. Results Two hundred and forty-four nursing students responded to the questionnaire. The mean total score was 79.64. Participants with religious beliefs presented lower scores, indicating a more negative attitude toward euthanasia. Participants in their second, third, or fourth year of the nursing degree scored higher, demonstrating a more positive attitude. Conclusions The attitude of nursing students toward euthanasia was remarkably positive. Working on ethical content during the degree course and clinical practice are factors that help to develop a more positive attitude. In addition, nursing education should encourage professional aspects to prevail over religious beliefs in euthanasia situations. (shrink)

Just as bodily actions are things you do with your body, mental actions are things you do with your mind. Both are different from things that merely happen to you. Where does the idea of mental action come from? What are mental actions? And why do they matter in philosophy? These are the three main questions answered in this paper. Section 1 introduces mental action through a brief history of the topic in philosophy. Section 2 explains what it is to (...) be a mental action in terms of intentional action. Section 3 argues that the fact that we can perform mental actions has some striking consequences concerning mental content. Section 4 shows how mental action helps to explain some important facts about self-knowledge and the normativity of thought. The conclusion mentions two further fruitful avenues for philosophical research on mental action. (shrink)

This paper attempts to reconstruct Hume's argument in Treatise 1.4.1, 'Of Scepticism with Regard to Reason'.

Background Informed consent is often cited as the “cornerstone” of research ethics. Its intent is that participants enter research voluntarily, with an understanding of what their participation entails. Despite agreement on the necessity to obtain informed consent in research, opinions vary on the threshold of disclosure necessary and the best method to obtain consent. We aimed to investigate Australian researchers’ views on, and their experiences with, obtaining informed consent. Methods Semi-structured interviews were conducted with 23 researchers from NSW institutions, working (...) in various fields of research. Interviews were analysed and coded to identify themes. Results Researchers reported that consent involved information disclosure, understanding and a voluntary decision. They emphasised the variability of consent interactions, which were dependent on potential participants’ abilities and interests, study complexity and context. All researchers reported providing written information to potential participants, yet questioned the readability and utility of this information. The majority reported using signed consent forms to ‘operationalise’ consent and reported little awareness of, and lack of support in implementing more dynamic informed consent procedures, such as verbal informed consent, that was fit for the purposes of their studies. Views on Human Research Ethics Committees varied. Some reported inconsistent, arduous inputs on the information form and consent process. Others expressed reliance on HRECs for guidance, viewing them as institutional safeguards. Conclusions This study highlights the importance of transparent relationships, both between researchers and participants, and between researchers and HRECs. Where the relationship with study participants was reported as more robust, researchers felt that they were better able to ensure participants made better, more informed decisions. Where the relationship with HRECs was reported as more robust, researchers were more likely to view them as institutional safeguards, rather than as bureaucratic hindrances. Conscientious and mindful researchers are paramount to ensuring the procedure accommodates individual requirements. This study advocates that when designing ethical informed consent practices, researchers should be integrated as autonomous players with a positive input on the process, rather than, in the worst case, predatory recruiters to be curtailed by information forms and oversight. (shrink)

Paulo Friere is considered to be one of the most influential educational philosophers of the twentieth century. Within many progressive circles, he would be considered the most important radical educational philosopher of our times, given his contribution to a revolutionary understanding of education and his certainty and faith that education can function as one of the most significant empowering and democratizing forces in the lives of the disenfranchised. In this deeply personal introduction to the man,and his ideas and their contribution (...) to ideas of progressive schooling, Antonia Darder reflects on her personal memories of time spent with Freire and his influence on her own work. (shrink)

Antonia Darder closely examines Freire's ideas as they are articulated in Pedagogy of the Oppressed, beginning with a historical discussion of his life and a systematic discussion of the central philosophical traditions that informed his revolutionary ideas. Darder explores Freire's fundamental themes and ideas, including issues of humanization, teacher/student relationship, reflection, dialogue, praxis, and his larger emancipatory vision. The book also includes a chapter-by-chapter close reading of the text with sample questions to prompt discussion and engagement with Freire's ideas, as (...) well as a new interview with Freire's widow, Ana Maria Araújo Freire, and a preface by Donaldo Macedo. -- from back cover. (shrink)

Aesthetic value empiricism claims that the aesthetic value of an object is grounded in the value of a certain kind of experience of it. The most popular version of value empiricism, and a dominant view in contemporary philosophical aesthetics more generally, is aesthetic hedonism. Hedonism restricts the grounds of aesthetic value to the pleasure enjoyed in the right kind of experience. But hedonism does not enjoy any clear advantage over a more permissive alternative version of value empiricism. This alternative is (...) aesthetic liberalism. On this view, an object’s aesthetic value is fully grounded in any value—not just the hedonic value—of a correct and complete experience of its sensory features. To demonstrate the advantages of liberalism over hedonism, I apply both views to analyze the aesthetic value of the Spring Temple Buddha and Anselm Kiefer’s Seraphim. I detail four advantages of liberalism over hedonism, and I conclude by defending liberalism from two kinds of objection. (shrink)

Basic actions are those intentional actions performed not by doing any other kind of thing intentionally. Complex actions involve doing one kind of thing intentionally by doing another kind of thing intentionally. There are both basic and complex mental actions. Some complex mental actions have a striking feature that has not been previously discussed: they have several distinct contents at once. This chapter introduces and explains this feature, here called “content plurality.” This chapter also argues for the philosophical significance of (...) this feature. The existence of content plurality offers a new explanation of transparent self-knowledge and suggests a new theory of inference. It also opens up a new conception of the relation between decisions to act and judgments about what ought to be done. (shrink)

Philosophy and Phenomenological Research, EarlyView.

Le mouvement ouvrier et étudiant de 68 a fissuré l'assise savante du pouvoir. Jacques Rancière, qui en prend acte, instaure un renversement fondamental : il ne saisit plus l'égalité comme but, mais comme point de départ. C'est d'une déconnexion avec l'ordre hiérarchique qu'elle procède. Sont ainsi mises en avant les capacités des opprimés à inventer des pratiques indociles. Pourtant, depuis une vingtaine d'années, Rancière tend à rétrécir la portée de ce geste : en le déplaçant vers le champ esthétique, il (...) le limite à des "redistributions polémiques du dicible et du visible". Ce livre rompt avec une telle orientation. Il élucide l'égalité dans des luttes impliquant la violence, réintroduit une rationalité du désir et de l'antagonisme. L'aspiration à abolir le rapport capitaliste fait pleinement partie de l'obstination lucide qui anime la confiance égalitaire. Ainsi radicalisée, l'égalité noue l'antagonisme, qui combat un ennemi à détruire, au litige, qui s'inclut dans le monde de l'adversaire par polémique. Elle rencontre les questions que le féminisme pose à l'universel, et s'empare de la défaite comme d'un moment immanent à sa pratique, tirant ses ressources de possibles déjà accomplis, mais aussi des chances manquées d'une lutte."--Page 4 of cover. (shrink)

You can come to know that you believe that p partly by reflecting on whether p and then judging that p. Call this procedure “the transparency method for belief.” How exactly does the transparency method generate known self-attributions of belief? To answer that question, we cannot interpret the transparency method as involving a transition between the contents p and I believe that p. It is hard to see how some such transition could be warranted. Instead, in this context, one mental (...) action is both a judgment that p and a self-attribution of a belief that p. The notion of embedded mental action is introduced here to explain how this can be so and to provide a full epistemic explanation of the transparency method. That explanation makes sense of first-person authority and immediacy in transparent self-knowledge. In generalized form, it gives sufficient conditions on an attitude’s being known transparently. (shrink)

How could Hannah Arendt, a German Jew who fled Germany in 1931, have reconciled with Martin Heidegger, whom she knew had joined and actively participated in the Nazi Party? In this remarkable biography, Antonia Grunenberg tells how the relationship between Arendt and Heidegger embraced both love and thought and made their passions inseparable, both philosophically and romantically. Grunenberg recounts how the history between Arendt and Heidegger is entwined with the history of the twentieth century with its breaks, catastrophes, and crises. (...) Against the violent backdrop of the last century, she details their complicated and often fissured relationship as well as their intense commitments to thinking. (shrink)

Aesthetic value is not as peculiar as we might think. We do not walk into museums expecting to find there a good so refined that it bears no continuity with the.

RESUMO Este artigo pretende analisar o tópico das "Duas Verdades" na história do pensamento budista. Seu objetivo consiste em elucidar esse tópico a partir do ponto de vista do "Satya-siddhi-śāstra". Parte-se aqui de uma consideração metodológica referente ao problema das múltiplas tradições intelectuais do universo budista, desenvolvendo-se uma análise do conceito das "Duas Verdades" presente no "Satya-siddhi-śāstra". ABSTRACT This article hopes to analyze the topic of the "Two truths" in the history of Buddhist thought. The subject is to elucidate this (...) topic from the point of view of the "Satya-siddhi-śāstra". The starting point is the methodological considerations concerning the multiple intellectual traditions present in the Buddhist universe developing an analysis of the "Two truths" as present in the "Satya-siddhi-śāstra". (shrink)

Introduction -- Overview of ethical thought -- Historical and theoretical rising of human rights and their international codification and protection -- Ethics of recognition -- Human dignity principle -- Other principles -- A changed and changing legal landscape -- Answering some questions -- Conclusion.

The future of awake bruxism assessment will incorporate physiological data, possibly electromyography of the temporal muscles. But up to now, temporal muscle contraction patterns in awake bruxism have not been characterized to demonstrate clinical utility. The present study aimed to perform surface EMG evaluations of people assessed for awake bruxism to identify possible different subtypes. A 2-year active search for people with awake bruxism in three regions of the country resulted in a total of 303 participants. Their inclusion was confirmed (...) through non-instrumental approaches for awake bruxism: self-reported questionnaire and clinical exam, performed by three experienced and calibrated dentists. Also, 77 age- and sex-matched healthy controls were recruited. Temporalis surface EMG was performed with a portable device. EMG signals were sent to a computer via Bluetooth 4.0 at a sampling rate of 1,000 Hz. Digital signal processing was performed using the commercial neuroUP software, transformed in RMS and then normalized for peak detection, in a 10 min session. Cluster analysis revealed three distinct subtypes of awake bruxism: phasic, tonic, and intermediate. Individuals with a predominance of EMG peaks/min were classified as the “phasic” subtype. Those with the highest EMG rest power were classified as the “tonic” subtype. There was also an “intermediate” subtype, when both variables remained low. Characterization of awake bruxism physiology is important for future establishment of instrumental assessment protocols and treatment strategies. (shrink)

Context and theory : Molefi Kete Asante and the Afrocentric idea -- Reason and analysis : Africana and new interpretations of reality -- Afrocentricity and modernism : innovation encounters and traditions -- Afrocentricity and post modernism : the moment of truth -- The paradigmatic rupture : critical Africology.

In his fascinating new book Games: Agency as Art, Nguyen endorses an experiential requirement on aesthetic judgment: apt aesthetic judgment requires phenomenal experience. His own aesthetics of agency captures three phenomenally manifest and aesthetically significant harmonies (and corresponding disharmonies). But his view can be significantly extended to capture much more of the rich texture of human agency. In this discussion, I argue that emotions of agency, patterns of attention, and affordances all can be phenomenally experienced as aspects of agency, and (...) that each has genuine aesthetic significance. (shrink)

The present work is completely grounded in the methodology of textual analysis as present in buddhist studies and has three essential pretentions. The first one is to discuss the relationship between the conceptual and non-conceptual dimensions of buddhist practice from the standpoint of the concept of the three wisdoms. The second one is to define a central standpoint able to judge the difference between buddhist practice proper and the therapeutic and scientific approaches to meditation. The third one tries to think (...) the complete autonomy of the conceptual dimension from an analysis of the relationship between the three wisdoms and the three worlds in the Satya-siddhi-Sãstra. (shrink)

Uma das formas do poder feminino-africano se manifesta de forma acentuada no campo da espiritualidade, tanto no mundo visível, ou seja, dos vivos, quanto no mundo invisível, o dos mortos. Este artigo faz parte de uma pesquisa em andamento, sobre o poder exercido pelas mulheres africanas e que raras vezes são consideradas ou visibilizadas como formas de poder na contramão de uma vasta literatura em que as mulheres, na sua maioria, são consideradas submissas. O interesse recai sobre práticas de tornar-se (...) djambakus, Balobêru, nganga, Mutombe ou tchimbanda em duas realidades, a guineense e a angolana. A riqueza dos relatos das experiências de uma guineense, moradora de Ziguinchor, Senegal, com foco nas tradições ancestrais para transmitir e explicar o sagrado por intermédio da história oral, reforçam a análise da concepção do lugar destas mulheres no exercício do poder ocultado. O trabalho é de caráter teórico-qualitativo: revisão de literatura, entrevistas e história oral. O recurso da oralidade dialoga com a condição de escassez de documentos escritos sobre curandeiras, djambacus, Balobêru e nganga que se dedicam a curar. Foi entrevistada uma djambakus que transita entre Guiné-Bissau e Senegal. Os resultados apontam para a potência de mulheres na prática sagrada de cura pelo encontro de conhecimentos populares, saberes africanos tradicionais, ancestrais e do bem-estar de suas comunidades ou tabancas. (shrink)

In October 2013, the Declaration of Helsinki was revised a seventh time in its 50 year history. While it is the most widely accepted set of ethical principles for the protection of patients participating in medical research, the Declaration of Helsinki has also been subject of constant controversy. In particular, its paragraph on the use of placebo controls in clinical trials divides the research community into active-control and placebo orthodox proponents, both continuously demanding revisions of the Declaration of Helsinki in (...) favour of their position. The goal of the present project is to compare the mainly theoretical controversy with regulatory implementation. We distributed a questionnaire to national drug regulatory authorities from different countries to collect information on the authorities’ respective approaches to interpretation and implementation of the Declarations’ placebo paragraph in the conduct of medical research. Our findings suggest that the majority of drug regulatory authorities have established a practice of a middle ground, allowing placebo controls in some instances. Various interpretations of “serious harm” and “methodological reasons” are proposed as well as safeguards to avoid abuse of the option to use placebo-controls. Leaving the placebo paragraph open to various interpretation is a result of the Declaration of Helsinki’s character as a guidance document. With the current version controversy will continue. The Declaration should be continued to be strengthened to enforce the appreciation of conducting medical research with the highest ethical standard. (shrink)

Any contextualist approach to knowledge has to provide a plausible definition of the concept of context and spell out the mechanisms of context changes. Since it is the dynamics of context change that carry the main weight of the contextualist position, not every mechanism will be capable of filling that role. In particular, I argue that one class of mechanisms that is most popularly held to account for context changes, namely those that arise out of shifts of conversational parameters in (...) discourses involving knowledge claims, are not suited to the job because they cannot account for the genuinely epistemic nature of the context shift. A form of epistemic contextualism that defines the context through the structure of our epistemic projects is suggested. Context changes in this account are linked to changes in the background assumptions operative in our epistemic projects and the methods used to carry out our inquiries. (shrink)

Nietzsche y Educación: conocimiento y cultura en el Estado Moderno Resumen: Este texto busca tejer algunas reflexiones sobre la relación entre la filosofía de Friedrich Nietzsche y el campo educativo, entendiendo sus indagaciones sobre las instituciones educativas modernas y los valores vinculados a este tipo de hombre. Vinculado al proceso de degeneración de la potencia instintiva humana y su animalidad, se estableció un modelo de conocimiento, basado en el ideal metafísico y la creencia incondicional de la verdad. La crítica dirigida (...) al Estado Moderno y su modelo de cultura, que pretendió instituir a filósofos/as y estudiosos/as como guías, considera que es necesario volver a hacer crecer los usos y funciones de estos sujetos en la sociedad, al buscar superar el dilema que los constituye hoy, como empleados y mantenedores del Estado. Pasando por distintas fases de su pensamiento, buscó ser un instrumento más para dotar al ámbito de la Filosofía de la Educación de un vínculo sólido con el filósofo alemán, a través del estudio de las relaciones entre Nietzsche y la Educación. Palabras-Clave: Conocimiento; Cultura; Educación; Friedrich Nietzsche. Nietzsche e Educação: conhecimento e cultura no Estado Moderno Resumo: Este texto busca tecer algumas reflexões acerca da relação entre a filosofia de Friedrich Nietzsche e o campo educacional, compreendendo suas indagações acerca das instituições de ensino modernas e os valores vinculados ao este tipo de homem. Atrelado ao processo de degeneração da potência instintiva humana e de sua animalidade ocorreu a fixação de um modelo de conhecimento, fundamentado no ideal metafísico e na crença incondicional da verdade. A crítica dirigida ao Estado Moderno e ao seu modelo de cultura, que pretendeu instituir os filósofos e eruditos enquanto guias, entende que é necessário o resgate dos usos e funções destes sujeitos na sociedade, buscando superar o dilema que os constitui hoje, como funcionários e mantenedores do Estado. Perpassando diferentes fases de seu pensamento buscou-se ser mais um instrumento para fornecer ao âmbito da Filosofia da Educação um vínculo sólido com o filósofo alemão, por meio do estudo das relações entre Nietzsche e a Educação. Palavras-chave: Conhecimento; Cultura; Educação; Friedrich Nietzsche. Nietzsche and Education: knowledge and culture in the Modern State Abstract: This text seeks to do some reflections on the relationship between Friedrich Nietzsche's philosophy and the educational field, understanding his inquiries about modern educational institutions and the values ​​linked to this type of man. United with the process of degeneration of human instinctual power and its animality, there was the establishment of a model of knowledge, based on the metaphysical ideal and on the unconditional belief of truth. The criticism directed at the Modern State and its model of culture, which intended to establish philosophers and scholars as guides, understands that it is necessary to rescue the uses and functions of these subjects in society, seeking to overcome the dilemma that constitutes them today, as employees and keepers of the state. Passing through different phases of his thought, we sought to be one more instrument to provide the scope of Philosophy of Education with a solid link with the German philosopher, through the study of the relationship between Nietzsche and Education. Keywords: Knowledge; Culture; Education; Friedrich Nietzsche. Data de registro: 10/08/2021 Data de aceite: 19/01/2022. (shrink)