Sustainability challenges typically occur across sectoral boundaries, calling the state, market, and civil society to action. Although consensus exists on the merits of cross-sector collaboration, our understanding of whether and how it can create value for various, collaborating stakeholders is still limited. This special issue focuses on how new combined knowledge on cross-sector collaboration and business models for sustainability can inform the academic and practitioner debates about sustainability challenges and solutions. We discuss how cross-sector collaboration can play an important role (...) for the transition to new and potentially sustainability-driven business models given that value creation, delivery, and capture of organizations are intimately related to the collaborative ties with their stakeholders. Sustainable alternatives to conventional business models tend to adopt a more holistic perspective of business by broadening the spectrum of solutions and stakeholders and, when aligned with cross-sector collaboration, can contribute new ways of addressing the wicked sustainability problems humanity faces. (shrink)

The objective of this paper is to examine the relationship between business model innovation, corporate sustainability, and the underlying organisational values. Moreover, the paper examines how the three dimensions correlate with corporate financial performance. It is concluded that companies with innovative business models are more likely to address corporate sustainability and that business model innovation and corporate sustainability alike are typically found in organisations rooted in values of flexibility and discretion. Business model innovation and corporate sustainability thus seem to have (...) their origin in the fundamental principles guiding the organisation. In addition, the study also finds a positive relationship between the core organisational values and financial performance. The analysis of the paper is based on survey responses from 492 managers within the Swedish fashion industry. (shrink)

Using survey responses from 400 fashion companies in Denmark, Norway, Sweden, Finland, and Iceland, we examine the diversity of strategic responses to institutional pressures for corporate social responsibility within the Nordic fashion industry. We also develop and test a new model of strategic responses to institutional pressures that encompasses both resistance and opportunity-seeking behaviour. Our results suggest that it is inconsistent pressures within, rather than between, stakeholder groups that shape strategic responses to CSR pressures and that increasing pressures stimulates opportunity-seeking (...) at the expense of compliance. (shrink)

The stakeholder approach has become a popular perspective in mainstream management and the corporate social responsibility (CSR) literature. However, it remains an open question as to how real-life managers actually view stakeholders and what rationales and logics are used for explaining the relationship between the firm and its constituencies. This article examines whom managers in multinational corporations (MNCs) consider to be their important stakeholders, and how they describe the societal responsibilities towards these groups and individuals. It is concluded that managers (...) still tend to hold a rather narrow (managerial) view of the firm and generally give priority to stakeholder groups who are directly involved in the firm's core transformation system. The conclusions are derived from interview and survey data from 647 managers in four MNCs. The paper is based on data collected as part of project RESPONSE: a European Union- and corporate-funded initiative on CSR. (shrink)

The purpose of this article is to develop a model of how managers perceive the responsibilities of business towards society. The article is based on the survey responses of more than 1,000 managers in eight large international firms. It is concluded that the managerial perceptions of societal responsibilities differ in some respects from the mainstream models found in the corporate social responsibility (CSR) and business ethics literature. The article is an output of RESPONSE: an EU- and corporate-funded research project on (...) managerial perceptions of CSR. (shrink)

Addiction is a central issue in a liberal society of autonomous citizens, as the nodal point of addiction is self-control - or rather the lack of it. By looking at different ways of problematizing and working upon addiction, one might also get some idea of different ways of conceptualizing and practicing freedom. The point of departure for my paper is practices of methadone maintenance in different regimes of drug treatment. The article illustrates how treatment practices produce different forms of subjectification (...) of drug addicts, depending on the discourses and technologies these practices articulate, and by implication, how they constitute different ways of problematizing freedom as something to be worked upon. My argument is based on interviews with managers of the drug treatment system in Copenhagen, documents concerning drug policy and drug treatment on a local and national level as well as addiction research. My analyses in this paper are tentative and a first report from a study currently under way. (shrink)

The relative merits and demerits of historically prominent views such as the correspondence theory, coherentism, pragmatism, verificationism, and instrumentalism have been subject to much attention in the truth literature and have fueled the long-lived debate over which of these views is the most plausible one. While diverging in their specific philosophical commitments, adherents of these historically prominent views agree in at least one fundamental respect. They are all alethic monists. They all endorse the thesis that there is only one property (...) in virtue of which propositions can be true, and so, in this sense, take truth to be one. The truth pluralist, on the other hand, rejects this idea. There are several properties in virtue of which propositions can be true. The literature on truth pluralism has been growing steadily for the past twenty years. This volume, however, is the first of its kind—the first collection of papers focused specifically on pluralism about truth. Part I is dedicated to the development, investigation, and critical discussion of different forms of pluralism. An additional reason to look at truth pluralism with interest is the significant connections it bears to other debates in the truth literature—the debates concerning traditional theories of truth and the deflationism/inflationism divide being cases in hand. Parts II and III of the volume connect truth pluralism to these two debates. (shrink)

This is the introduction to Moretti, Luca and Nikolaj Pedersen (eds), Non-Evidentialist Epistemology. Brill. Contributors: N. Ashton, A. Coliva, J. Kim, K. McCain, A. Meylan, L. Moretti, S. Moruzzi, J. Ohlorst, N. Pedersen, T. Piazza, L. Zanetti.

The aim of this paper is to provide an overview of various forms of alethic pluralism. Along the way we will draw a number of distinctions that, hopefully, will be useful in mapping the pluralist landscape. Finally, we will argue that a commitment to alethic disjunctivism, a certain brand of pluralism, might be difficult to avoid for adherents of the other pluralist views to be discussed. We will proceed as follows: Section 1 introduces alethic monism and alethic pluralism. Section 2 (...) presents a distinction between strong and moderate versions of monism and pluralism, understood as theses about the existence of truth properties. Section 3 introduces four pluralist positions: strong alethic pluralism, alethic disjunctivism, second-order functionalism and manifestation functionalism. These positions are classified using the basic framework from Section 2, and a further distinction between pure and mixed versions of pluralism is drawn. Interestingly, alethic disjunctivism and the two kinds of functionalism—i.e. three out of four positions— have a mixed character. They incorporate a monist thesis. The only pure form of pluralism is strong alethic pluralism. Section 4 adds another distinction to the stock: one-level and two-level views. Each of the mixed positions operates with two levels, locating certain “alethically potent”—or grounding—properties at a lower level and others at a higher level. We briefly discuss the nature of grounding. In Section 5, we answer a question about mixed, two-level views, viz. whether they are as much monist as pluralist in nature, or more. They are not. Section 6 is devoted to the task of arguing that the strong pluralist, the second-order functionalist, and the manifestation functionalist will find it hard to deny a commitment to alethic disjunctivism. (shrink)

Although research has examined factors influencing understanding of informed consent in biomedical and forensic research, less is known about participants' attention to details in consent documents in psychological survey research. The present study used a randomized experimental design and found the majority of participants were unable to recall information from the consent form in both in-person and online formats. Participants were also relatively poor at recognizing important aspects of the consent form including risks to participants and confidentiality procedures. Memory effects (...) and individual difference characteristics also appeared to influence recall and recognition of consent form information. (shrink)

Here is a well-known thought about truth: Truth consists in correspondence with reality. A sentence is true just in case what it says corresponds with how the world is. Theories of truth that incorporate this thought are naturally regarded as robust or “heavyweight”. Truth is to be understood in a realist fashion. The world decides what is true and what is not. A recent incarnation of the correspondence view is found in truth-maker theories, whose adherents maintain that truths are true (...) in virtue of there being something – a truth-maker – in the world that makes them so.2. (shrink)

In this paper I will argue that the distinction between biological life and political life as found in Hannah Arendt’s reading of Aristotle and later repeated and elaborated by Giorgio Agamben under the headings of and, is in fact a fertile point of entry to, and the only viable option in order the grasp what constitutes the political as such for Aristotle. By hashing out the conceptual steps necessary for the establishment of what can be called a “political community”, I (...) seek to illuminate how the distinction upon which much of Arendt’s and Agamben’s works rests, does indeed play a vital role in the work of Aristotle. By clarifying the nature of a “political community” according to Aristotle, this paper thus seeks to make a proper assessment of the thought of both Arendt and Agamben possible. (shrink)

The magical number three has provided the template for this comparative study of Freudian psycho-analysis and Husserlian phenomenology. "Three" should be considered the number of dialectics; the method in the study to let three distinct thematisations succeed each other should find its legitimation in dialectics. The relationship between psycho-analysis and phenomenology as that between two dialectic theories might well call for a dialectic interpretation. It should be difficult from a straightforward and unambiguous interpretation to give full credit to the rich (...) and equivocal meaning of psycho-analysis and phenomenology. I hope to have shown in the presentation above, that it is possible by accentuating different sides of the two scientific disciplines to reach different conclusions regarding their relationship. For a full account of this relationship these different conclusions should be placed together and viewed in their internal coherence as a dialectical unity. Thus none of the three sections of the text should be considered apart from the others. In the first section of the paper, the first thematisation, I tried to spell out the discrepancies between Freud and Husserl as clearly as possible. The point of departure here was the Freudian notion of the "psychical apparatus," and Husserl's doctrine of "intentional consciousness." The models built around these central notions can be shown to have a paradigmatic meaning for the development of Freud's and Husserl's psychological projects. Conceiving the subject as psychical apparatus, Freud thought it possible to make psychology a natural science. The subject could be treated like a mechanical apparatus, that is a machine admitting the general laws of motion. - In contrast, Husserl thought psychology should depart from natural science in its scientific selfunderstanding, and join the humanities instead. Psychology's departure from natural science, Husserl found legitimized in the subject's essential character of intentional consciousness. According to Husserl, man as a conscious being could not be reduced to a thing in the natural world. On the contrary, the aprioric basis for the world should be found in intentional consciousness, which constitutes the "world" as a meaningful coherence related to the subject. Freud's and Husserl's conceptions of psychology were traced to historical roots in respectively positivism, naturalism and mechanical materialism on the one hand, and rationalism, humanism and idealism on the other. In this first interpretation the relationship between psycho-analysis and phenomenology seemed to be antithetical, the two theoretical projects representing opposite poles with regard to cartesian dualism. Although in some ways caricaturing the theories in this one-sided interpretation, I tried to show, that such interpretation is possible with bases in the texts of Freud and Husserl. The decided one-sidedness of the first thematisation should, however, be balanced by the competing interpretation in the second section of the paper. In the second thematisation, I tried to show, that both psycho-analysis and phenomenology in their concrete psychological projects went beyond their points of departure. Although Freud as a scientist of the 19th century naturally found his theoretical language in the successful natural sciences, from which his scientific career started, he decisively broke with this frame of reference in his descriptions of the pathological problems from his clinical praxis. In contrast to the abstract metapsychology of the psychical apparatus, Freud in his clinical psychology departed from mechanism in his attempts to interpret the meaning of the patient's neurotic symptom. The clinical attitude of Freud might resemble phenomenologists' openness towards the meaning of the phenomena, and the case-histories of Freud often read like clinical analyses stemming from existential- phenomenological psychiatrists. - Correspondingly, although Husserl started from the tradition of German philosophy of consciousness, also he can be seen to go beyond the premises of his wellsprings. Starting with a notion of intentionality as consciousness's active positing meaningful objects, Husserl later was led to consider a deeper level of intentionality, a "functioning intentionality," that would situate the subject in a "world" prior to any thematic perceptual act. With the notion of functional intentionality and its further development in Merleau-Ponty's philosophy of the "body-subject," phenomenology seems to have come close to the Freudian doctrine of the unconscious. From this second interpretation it seemed to follow, that a meeting between psycho-analysis and phenomenology should be possible, by cutting off the mechanistic parts from psychoanalysis and the idealistic parts from phenomenology. The hindrance for such meeting should apparently be found in the divergent theoretical prejudices stemming from the ideological climates in which the theories were hatched. None of these two apparently contradictory interpretations, that of the first and second thematisation, should, however, rule out the other. To the question which interpretation is the right one, we should answer "both... and," or perhaps better "Neither... nor." Freud and Husserl in fact held contradictory views in their explicit scientific self-understanding. On the other hand, much of the controversy was caused by theoretical prejudices not essential to the central enterprise of psycho-analysis and phenomenology. And yet, the theoretical work of Freud and Husserl should be considered in its entirety, not omitting parts that do not fit the interpretative context. Freud's mechanistic theories must be read in connection with his clinical/phenomenological psychology, Husserl's doctrine of transcendental consciousness together with his concrete analyses of the world and the body. Freud sticked to his mechanistic metaphors throughout his life, not just because mechanic materialism was his scientific point of departure, but also because he found the models of the psychical apparatus useful to picture the subject-matter of psycho-analysis, the unconscious as it is discovered by the analytic method. Correspondingly, Husserl found in transcendental idealism a metaphysical horizon apparently suited for his main theoretical project, to un-cover by phenomenological reflexion man in his free and conscious being. In this way Freud's materialism and Husserl's idealism might find their limited justification, not in the absolutistic sense set forth in the first section, but in relation to their weighting different aspects of the subject/object dialectic of man. This point of view I tried to explicate in the third section of this paper. In the subject/object dialectic Freud seems to underline man's existence as object, his being ruled by the mechanic, the irrational, the infantile, the unconscious. In contrast, Husserl underlines man's existence as subject, his free and conscious openness towards the world and the future. This difference I characterized with the notions of Ricoeur as respectively an "archeology" and a "teleology" of the subject. And yet the difference between Freud and Husserl is that of a weighting different sides of the subject/object dialectic, not of an exclusive thematisation of man as either subject or object. Freudian archaeology is supplemented by an implicit teleology, Husserlian teleology by an implicit archeology. On the background of such interpretation the relationship between psycho-analysis and phenomenology should be seen neither as the polarity of the first thematisation, nor as the synthesis of the second. Psycho-analysis and phenomenology both contradict and imply each other in a relationship that should be termed dialectical. With this third interpretation the paper ended. At last I noted that the problems raised by the controversy on the subject/object dialectic of man should not easily be solved. Instead, the question "what is man" should have to be answered continuously in a concrete historical reflextion or dialogue. Yet I think it safe to conclude, that any psychological consideration has to take into consideration, both man's archeological and his teleological features, thus not allowing the one perspective completely to rule out the other. (shrink)

Background: A fair distribution of healthcare services for older patients is an important challenge, but qualitative research exploring clinicians’ consideration in daily clinical prioritisation in healthcare services for the aged is scarce.Objectives: To explore what kind of criteria, values, and other relevant considerations are important in clinical prioritisations in healthcare services for older patients.Design: A semi-structured interview-guide was used to interview 45 clinicians working with older patients. The interviews were analysed qualitatively using hermeneutical content analysis and template organising style.Participants: 20 (...) physicians and 25 nurses working in public hospitals and nursing homes in different parts of Norway.Results and interpretations: Important dilemmas relate to under-provision of community care and comprehensive approaches, and over-utilisation of certain specialised services. Overt ageism is generally not reported, but the healthcare services for the aged seem to be inadequate due to more subtle processes, for example, dominating considerations and ideals and operating conditions that do not pay sufficient attention to older patients’ needs and considerations of justice. Clinical prioritisations are described as being dominated by adapting traditional biomedical approaches to the operating conditions. Many of the clinicians indicate that there is a potential for improving end of life decisions and for reducing exaggerated use of life-prolonging treatment and hospitalisations.Conclusion: The interviews in this study indicate that considerations of justice and patients’ perspectives should be given more attention to strike a balance between specialised medical approaches and more general and comprehensive approaches in healthcare services for older patients. (shrink)

In this article, I critically assess Hélène Landemore's new model of Open Democracy, asking whether it requires of citizens to blindly defer to the decisions of the mini-public. To address this question, I, first, discuss three institutional mechanisms in Open Democracy, all of which can be read to grant citizens democratic control. I argue that neither the capacity to authorize the selection mechanism (random sortition), nor the lottocratic conception of political equality, nor the self-selection mechanisms of Landemore's model deliver the (...) form of control that would insulate Open Democracy from the charge of blind deference. I then discuss the direct democracy mechanisms that Landemore incorporates into her model. Although these devices grant citizens control and, by extension, offer the resources for repudiating the charge of blind deference, they also, I argue, subvert the logic of Landemore's lottocratic model, rendering Open Democracy predictably unstable. Given the deliberative asymmetries between the mini-public and the citizenry, a high frequency of bottom-up challenges is to be expected that would throw the whole system into jeopardy. Thus, the challenge for lottocrats is to show how democratic control can be achieved in a lottocratic system without undermining the benefits of the legislature by lot. (shrink)

The purpose of the present chapter is to survey the work on epistemic norms of action, practical deliberation and assertion and to consider how these norms are interrelated. On a more constructive note, we will argue that if there are important similarities between the epistemic norms of action and assertion, it has important ramifications for the debates over speech acts and harm. Thus, we hope that the chapter will indicate how thinking about assertions as a speech act can benefit from (...) a broader action theoretic setting. We will proceed as follows. In Section 2, we provide a survey of epistemic norms of action and practical deliberation. In Section 3, we turn to the epistemic norms of assertion. In Section 4, we consider arguments for and against commonality of the epistemic norms of actions, practical deliberation and assertion. In Section 5, we discuss some of the ramifications of the debates over epistemic norms of assertion such as whether they may be extended to other linguistic phenomena such as Gricean implicature. In Section 6, we consider the consequences of the debate about the epistemic norms of action and practical deliberation for debates about speech and harm. (shrink)

In this paper I will argue that the distinction between biological life and political life as found in Hannah Arendt’s reading of Aristotle and later repeated and elaborated by Giorgio Agamben under the headings of (“bare life”) and (“qualified life”), is in fact a fertile point of entry to, and the only viable option in order the grasp what constitutes the political as such for Aristotle. By hashing out the conceptual steps necessary for the establishment of what can be called (...) a “political community”, I seek to illuminate how the distinction upon which much of Arendt’s and Agamben’s works rests, does indeed play a vital role in the work of Aristotle. By clarifying the nature of a “political community” according to Aristotle, this paper thus seeks to make a proper assessment of the thought of both Arendt and Agamben possible. (shrink)

Including empirical examples and theoretical clarifications on many of the analytical issues raised in his recently published Down to Earth, this conversation with Bruno Latour and his collaborator, Danish sociologist Nikolaj Schultz, offers key insights into Latour’s recent and ongoing work. Revolving around questions on political ecology and social theory in our ‘New Climatic Regime’, Latour argues that in order to have politics you need a land and you need a people. This interview present reflections on such politics, such land (...) and such people, and it ends with a call for a sociology that takes up the task of connecting the three by investigating what he and Schultz call ‘geo-social classes’. The interview was conducted by Jakob Stein in Paris in November 2018. (shrink)

According to the widely endorsed Knowledge Account of Assertion, the epistemic requirements on assertion are captured by the Knowledge Norm of Assertion, which requires speakers only to assert what they know. This paper proposes that in addition to the Knowledge Norm there is also an Epistemic Propositional Certainty Norm of Assertion, which enjoins speakers only to assert p if they believe that p on the basis of evidence which makes p an epistemic propositional certainty. The paper explains how this propositional (...) certainty norm accounts for a range of data related to the practice of assertion and defends the norm against general objections to certainty norms of assertion put forward by Duncan Pritchard, John Turri, and Timothy Williamson, by drawing on linguistic theories about epistemic modals and gradable predicate semantics. Together these considerations show that the prospects of a certainty account of assertion are much more promising than is usually assumed. (shrink)

The twenty-first century has witnessed a pervasive militarization of aesthetics with Western military institutions co-opting the creative worldmaking of art and merging it with the destructive forces of warfare. In Martial Aesthetics, Anders Engberg-Pedersen examines the origins of this unlikely merger, showing that today's creative warfare is merely the extension of a historical development that began long ago. Indeed, the emergence of martial aesthetics harkens back to a series of inventions, ideas, and debates in the eighteenth and early nineteenth (...) century. Already then, military thinkers and inventors adopted ideas from the field of aesthetics about the nature, purpose, and force of art and retooled them into innovative military technologies and a new theory that conceptualized war not merely as a practical art, but as an aesthetic art form. This book shows how military discourses and early war media such as star charts, horoscopes, and the Prussian wargame were entangled with ideas of creativity, genius, and possible worlds in philosophy and aesthetic theory (by thinkers such as Leibniz, Baumgarten, Kant, and Schiller) in order to trace the emergence of martial aesthetics. Adopting an approach that is simultaneously historical and theoretical, Engberg-Pedersen presents a new frame for understanding war in the twenty-first century. (shrink)

The Rawls–Habermas debate is having a revival. In this article I argue that both philosophers develop different freestanding conceptions of political legitimacy, and show how they diverge when it comes to how political legitimacy can be justified. Habermas is looking for a deeper justification than Rawls will allow for. I then proceed to show how the different meta-ethical positions yield two different versions of democratic theory, focusing in particular on rights and popular sovereignty. I demonstrate how both conceive of the (...) co-originality of private and public autonomy, and subsequently take issue with Habermas’ reading of Rawls. I argue that Rawls should not be understood as a natural rights theorist, that Habermas misunderstands the role of the original position, and that Rawls cannot be considered a strong constitutionalist. Thus, the real difference between Rawls and Habermas revolves around their different conceptions of political legitimacy. (shrink)

In this critical comment, we argue that nondemocratic, but decent regimes fail to constitute legitimate governance under Applbaum’s free group agency account. To make this case, we first introduce the three principles of liberty, equality and agency that Applbaum takes to flow directly from his free agency conception of legitimacy. Against this backdrop, we discuss Applbaum’s claim that a nondemocratic regime along the lines of a Rawlsian decent consultation hierarchy could meet the threshold of legitimacy. Contrary to this suggestion, we (...) argue that nondemocratic, but decent regimes cannot claim legitimacy under Applbaum’s account because they are constitutively inegalitarian, thus failing to adequately grant citizens the equal normative power without which legitimacy is unattainable under the free group agency account. (shrink)

Intuitions about contextualist cases such as Cohen’s airport case pose a problem for classical anti-skeptical versions of invariantism. Recently, Tim Black, Jessica Brown, and Patrick Rysiew have argued that the classical invariantist can respond by arguing that pragmatic aspects of epistemic discourse are responsible for the relevant problematic intuitions. This paper identifies the mechanisms of conversational implicature and impliciture as the basic sources of hope for this explanatory strategy. It then argues that neither of these sources provides the classical invariantist (...) with a convincing response to the airport case and its analogs. (shrink)

This article examines Swedish, Danish and Norwegian governments’ participation in the European Return Platform for Unaccompanied Minors project and its failed attempts to deport unaccompanied minors to Afghanistan. It argues that ERPUM is an interesting and urgent case of a “deportation corridor”, and suggests that this framework can benefit from analysis through normative and applied ethics and in particular discussions of feasibility constraints. It therefore identifies and critically assesses two nationalistic arguments for deportation common in Nordic politics, based on appeals (...) credibility and humanitarianism. Considering the growth of nationalistic immigration policies in Nordic states, the article turns the usual discussions of feasibility on its head by showing that not only cosmopolitan, but also nationalistic ethics must face up to charges of lacking realism. More specifically, it argues that the case of ERPUM illustrates how nationalistic deportation ethics can rely on inconsistent normative and erroneous empirical assumptions, which can be criticized for their arbitrariness, ideological grounding and lacking feasibility. (shrink)

The policy of earmarked paternity leave aims to promote mothers’ position in the labor market and fathers’ relationship with their child. Critics argue that the policy prevents parents from pursuing their own ideas about what is best for them. This provides reason to consider whether the policy is paternalistic or, in other ways, disrespectful of parental autonomy. I argue that the state implicates itself in the gender inequalities that result from parents’ unequal parental leave agreements when the state financially facilitates (...) such agreements. This argument for earmarked paternity leave is not disrespectful of parental autonomy. (shrink)

In both philosophical and linguistic research, the explicit cancelability test is widely used to distinguish semantic contents from conversational implicatures. Assuming a straightforward relation between semantic content and explicit cancelability, a researcher might think that: if the proposition _p_ is expressed semantically by an utterance, then _p_ is not explicitly cancelable. In this paper, however, I argue for two amendments to this assumption. First, following Jerrold Sadock, I argue that the semantic content of an ambiguous utterance may be explicitly cancelable. (...) Against this widely accepted view, a recent paper by Arthur Sullivan argues that the ambiguity problem should be rejected. I respond to Sullivan’s arguments and argue that the ambiguity problem remains despite Sullivan’s objections. Second, I argue that there is also another type of case complicating the relation between semantic content and explicit cancelability. In some cases where an utterance of a sentence _s_ semantically expresses the proposition that _p_, certain resources that speakers have available for metalinguistic communication may be employed to make _p_ satisfy a sufficient condition for explicit cancelability, although _s_ is not ambiguous. These two weaknesses of the explicit cancelability test have important implications for its diagnostic use. (shrink)

This article investigates the hitherto under-examined relations between affirmative action, paternalism and respect. We provide three main arguments. First, we argue that affirmative action initiatives are typically paternalistic and thus disrespectful towards those intended beneficiaries who oppose the initiatives in question. Second, we argue that not introducing affirmative action can also be disrespectful towards these potential beneficiaries because such inaction involves a failure to adequately recognize their moral worth. Third, we argue that the paternalistic disrespect involved in affirmative action is (...) alleviated when the potential beneficiaries’ preferences against such initiatives are adaptive. We conclude that although there is a relevant sense in which paternalistic affirmative action is disrespectful, it may well be more disrespectful not to pursue such policies. (shrink)

Vann McGee claims that open-ended schemas are more innocuous than ordinary second-order quantification, particularly in terms of ontological commitment. We argue that this is not the case.

Secretion is a fundamental cellular process involving the regulated release of intracellular products from cells. Physiological functions such as neurotransmission, or the release of hormones and digestive enzymes, are all governed by cell secretion. Anomalies in the processes involved in secretion contribute to the development and progression of diseases such as diabetes and other hormonal disorders. To unravel the mechanisms that govern such diseases, it is essential to understand how hormones, growth factors and neurotransmitters are synthesized and processed, and how (...) their signals are recognized, amplified and transmitted by intracellular signaling pathways in the target cells. Here, we discuss diverse aspects of the detailed mechanisms involved in secretion based on mathematical models. The models range from stochastic ones describing the trafficking of secretory vesicles to deterministic ones investigating the regulation of cellular processes that underlie hormonal secretion. In all cases, the models are closely related to experimental results and suggest theoretical predictions for the secretion mechanisms. (shrink)