A deaf lesbian couple who chose to have a deaf child receive a lot of criticismA deaf lesbian couple in the US deliberately tried to create a deaf child. Sharon Duchesneau and Candy McCullough hoped their child, conceived with the help of a sperm donor, would be deaf like the rest of the family. Their daughter, five year old Jehanne, is also deaf and was conceived with the same donor. News of the couple choosing to have a deaf child has (...) only been revealed with the birth of their son Gauvin.1–4To increase their chance of having a deaf baby the women sought a deaf sperm donor from a sperm bank but were told that congenital deafness is “precisely the sort of condition” that disqualifies would-be donors. Rather than dismiss the idea they found their own sperm donor by asking a deaf friend who comes from a family with five generations of deafness.1The women, both professionals in the mental health field, insist that they would still love …. (shrink)

In Victoria, Australia, some parents are now able to select embryos free from genetic disease which will provide stem cells to treat an existing siblingA n Australian couple from Victoria have been given permission to use in vitro fertilisation technology to screen an embryo in order to “create a `perfect match’ sibling” for their seriously ill child. In vitro fertilisation is regulated in Victoria by the Infertility Treatment Authority which restricts access to people who are medically infertile or who have (...) a family history of genetic disease. The approval given to the Victorian couple is for a new application of IVF consisting of preimplantation genetic diagnosis together with tissue typing.The couple’s three year old daughter Christina has Fanconi’s anaemia, a rare genetic condition, that means she will die before she turns 15 unless she receives blood from the umbilical cord of a “perfect match” sibling. Some people are saying this use of IVF amounts to the creation of a genetically engineered “designer” baby. 1–6Preimplantation genetic diagnosis is an IVF technique …. (shrink)

Following an investigation of the football clubs using hypoxic air machines, the Australian Football League has decided not to ban the machines. This seems, however, to be a reluctant decision since it appears that some AFL officials still feel there is something undesirable about the use of the machines. Use of the machines raises questions about performance enhancement and the role of technology. It prompts consideration of the grounds for banning performance enhancing devices or substances and raises questions about what (...) constitutes a drugA machine being used by Australian footballers, which is designed to imitate the effects of high altitude training and enhance performance has prompted an investigation by the Australian Football League and sparked debate in the media. The AFL decided not to ban the machine but a sense of unease about its use remains and there seems to be some difficulty in articulating the cause of that unease. The league’s medical officers say the hypoxicators do not contravene their antidoping code or the league’s rules,1,2 but according to at least one AFL official, the use of the machines is “sending the wrong message …. (shrink)

Conceiving a child by way of embryo selection and tissue matching to benefit a sick sibling is generally justified on the grounds that as well as the potential to save the sick child, there is a benefit for the new baby. The new baby is selected so he or she will not have the disease suffered by the first child. It is not possible, however, to select against conditions for which there is no test and Jamie Whitaker’s birth is a (...) case where the process of in vitro fertilisation with tissue matching is viewed as being of benefit only to a third party—the sick child. Some people object to using the technology for this purpose. There are also good reasons to argue that the technology should be used to save a sick child, and that it would be morally remiss for Jamie’s parents not to consent to the use of his cord blood. (shrink)

A n IVF mixup has resulted in a white couple giving birth to black twins. Prior to DNA testing, no one can be sure whether the white woman’s eggs were fertilised with the black man’s sperm, or the black couple’s embryo was mistakenly implanted in the white woman. It is believed that Mr and Mrs A, the white couple, want to keep the babies and there is conjecture about Mr and Mrs B, the black couple, wanting them too.1 Under the (...) Human Fertilisation and Embryology Act 1990, a woman who has a child born through IVF, even if it is not genetically hers, is the “legal mother”. Paternity, however, is “open to legal interpretation”.1–3News of the mixup has elicited a range of reactions. It is thought …. (shrink)

In this paper we identify and evaluate arguments for and against offering assisted reproductive technologies , specifically IVF, to HIV discordant couples . The idea of offering ART to HIV discordant couples generates concerns about safety and public health and raises questions such as: what is an acceptable level of risk to offspring and should couples who want this assistance be subject to selection criteria; should they undergo scrutiny about their suitability as parents when those who are able to conceive (...) naturally face no such scrutiny and people with other illnesses are given access to ART? We conclude that offering ART to HIV discordant couples is likely to produce more benefit than harm and violates no ethical principles. Nevertheless, a decision to deny treatment need not constitute unjustified discrimination. (shrink)

The Brisbane Supreme Court has denied an Australian woman’s request to harvest and freeze her dead fiancé’s sperm for future impregnation. After she was denied access to the sperm, the woman learnt that her fiancé may have been a sperm donor and she began checking to find out if his sperm was still available. Given what we know, there is a good ethical argument that the woman should have access to the sperm and should be allowed to have her dead (...) fiancé’s child.Another aspect of this case is that it illustrates the way in which ethics, law, and personal opinion can differ. (shrink)

Compulsory genetic tests which reveal a predisposition to brain damage could be of more use in preventing harm than brain scans which show that damage has already occurredAmid calls for a ban on boxing the Victorian government in Australia introduced compulsory brain scans for professional boxers in June 2001. Some people think the introduction of this new law is a “tough” measure. Others think the law is of limited value because the damage has already occurred by the time something shows (...) up on a brain scan. The Victorian government is also considering the introduction of compulsory genetic tests that indicate a predisposition to brain damage.Nathan Croucher, a 24 year old construction worker and champion amateur boxer has been banned from professional boxing after a compulsory brain scan showed an abnormality which makes him susceptible …. (shrink)

When is commodification acceptable?Preimplantation genetic diagnosis is usually restricted to couples who are eligible for in vitro fertilisation —infertile couples or those with a history of genetic disease. The Human Fertilisation and Embryology Authority in England and the Infertility Treatment Authority in Australia have both given permission for PGD with tissue typing to detect human leucocyte antigen compatibility in order to save an existing sibling with a life threatening condition. The procedure has also been carried out in the United States.1Heavy (...) criticism followed the February 2002 ruling of England’s HFEA to allow a family to try for a child who is free of thalassaemia and a “perfect match” for a sick sibling.2 Then in August …. (shrink)

Is it right to use pre-implantation genetic diagnosis to select an embryo free of the gene for early-onset Alzheimer’s disease?A 30 year old woman with the gene for early-onset Alzheimer’s disease, who seems certain to develop the disease by the time she is 40, has used IVF and preimplantation genetic diagnosis to select an embryo that is free of the mutant gene. The woman, a geneticist, has given birth to a mutation-free child. This marks the first time that preimplantation genetic (...) diagnosis has been used to “weed out” an embryo with the defect.1–3Early-onset Alzheimer’s is an inherited, incurable disease striking people …. (shrink)

High Culture is a collection of essays containing reflections on addiction. Some of the essays are original and some are reprints. The volume is divided into two sections: the first dealing with literature, philosophy, and the arts and the second with sociology, psychology, and the media. The editors promise something different from the usual “insistent drive to medicalize, discipline, rehabilitate, and contain the subject of drugs within frameworks that disguise deeply rooted moral and religious fears, values and beliefs or prejudices” (...) and that addiction will emerge as something “not reducible to substance abuse or compulsiveness per se” .The editors also lay claim to demonstrating the “complexity, creative value and diversity” of addiction in place of what they describe as the limited …. (shrink)

Cloning Trevor, a story about therapeutic cloning research, appeared in the June issue of The Atlantic Monthly. The story gives a human face to the people whom therapeutic cloning could benefit. It presents an argument for government funding and it puts the usual calls for a moratorium on embryonic stem cell research to allow for more debate, in a less favourable light. The story also highlights some problems with ethical oversight.

Overruling of law said to establish the “right not to be born”The French government has given in to public pressure and overturned a controversial legal ruling which recognised the right of a disabled chld to seek damaages. Most notably, the ruling, widely described as establishing a child's right “not to be born”, had provoked “outrage” amongst groups defending the rights of the disabled and led to a ban on prenatal scans by French gynaecologists. Once again, only parents will be able (...) to seek damages but some people think the ruling has been misinterpreted.The Perruche judgment, a controversial ruling which has been said to establish the “right not to be born”, has now been overruled by a majority of the National Assembly of the French Parliament.1, 2 A bill has been put forward which states “no one can sue for damages for the sole fact of their birth”. It was considered by the senate until January 22, 2002.2In 1982, Josette Perruche discovered red spots covering her four year old daughter. The child was diagnosed with German measles. Mrs Perruche told her …. (shrink)

The Kennedy Krieger lead paint study received a lot of attention after a US Court of Appeals ruled that a parent cannot consent to the participation of a child in non-therapeutic research. The ruling has raised fears that, if it goes unchallenged, valuable research might not proceed and ultimately all children would be harmed. The author discusses significant aspects of the study that have been neglected, and argues that the study was unethical because it involved injustice and its design meant (...) that the study lacked importance and value. Issues of benefit, risk, and consent are vital, but it is sometimes a mistake to consider these issues before settling questions about justice and the importance and value of a research project. The author concludes by offering a strategy for researchers and reviewers of research to appreciate, in a vivid way, the implications of research participation. (shrink)

National electronic health record initiatives are in progress in many countries around the world but the debate about the ethical issues and how they are to be addressed remains overshadowed by other issues. The discourse to which all others are answerable is a technical discourse, even where matters of privacy and consent are concerned. Yet a focus on technical issues and a failure to think about ethics are cited as factors in the failure of the UK health record system. In (...) this paper, while the prime concern is the Australian Personally Controlled Electronic Health Record (PCEHR), the discussion is relevant to and informed by the international context. The authors draw attention to ethical and conceptual issues that have implications for the success or failure of electronic health records systems. Important ethical issues to consider as Australia moves towards a PCEHR system include: issues of equity that arise in the context of personal control, who benefits and who should pay, what are the legitimate uses of PCEHRs, and how we should implement privacy. The authors identify specific questions that need addressing. (shrink)

Literary accounts of traumatic events can be more informative and insightful than personal testimonials. In particular, reference to works of literature can give us a more vivid sense of what it is like to receive a devastating diagnosis. In turn this can lead us to question some common assumptions about the nature of autonomy, particularly for patients in these circumstances. The literature of concentration camp and labour camp experiences can help us understand what it is like to have one's life-plans (...) altered utterly and unexpectedly. Contrary to common views of autonomy which have difficulty in characterising autonomous action when long-standing assumptions are suddenly lost, these examples show that autonomy is possible in these circumstances. We need a theory of autonomy which can deal with traumatic events and is useful in the clinical context. (shrink)

Intercellular signaling by growth factors, hormones and neurotransmitters produces second messenger molecules such as cyclic adenosine monophosphate (cAMP) and diacylglycerol (DAG). Protein Kinase A and Protein Kinase C are the principal effector proteins of these prototypical second messengers in certain cell types. Recently, novel receptors for cAMP and DAG have been identified. These proteins, designated EPAC (Exchange Protein directly Activated by cAMP) or cAMP‐GEF (cAMP regulated Guanine nucleotide Exchange Factor) and CalDAG‐GEF (Calcium and Diacylglycerol regulated Guanine nucleotide Exchange Factor) or (...) RasGRP (Ras Guanine nucleotide Releasing Protein) are able to mediate some of the physiologic effects of the second messengers in a protein‐kinase‐independent fashion. These proteins are exchange factors for Ras family GTPases that operate in pathways that run parallel to the classic kinase‐dependent pathways. The rapidly emerging recognition of the functions of these “non‐kinase” effectors in diverse processes such as insulin secretion, thymocyte development, asthma and malignant transformation creates new opportunities for discovery and identifies potential new therapeutic targets. BioEssays 26:730–738, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Preimplantation genetic diagnosis—the risks are unknown and human dignity could be compromisedMerle Spriggs argues that there are no good reasons to prevent a couple utilising preimplantation genetic diagnosis when the sole aim of the procedure is that the resultant child is a compatible umbilical cord blood donor for a sick sibling.1 I agree with much of the argument to support this, however, I believe Spriggs has omitted one important point and underplayed another.The risk of PGD to the child (...) born as a result of this process has not been fully studied. Therefore the parents are exposing the child to potential …. (shrink)

I note with interest the Controversy regarding a baby born free of an inherited predisposition to early onset Alzheimer’s disease through the use of preimplantation genetic diagnosis .1,2 As the medical geneticist for the PGD programme for single gene disorders in Melbourne, Australia, I have seen many couples who have considered PGD for a wide range of genetic conditions. My observation is that many couples look to PGD for “milder” conditions and adult onset conditions for which they are not comfortable (...) to have traditional prenatal diagnosis and termination of pregnancy.An example of this is that in the last 11 years our unit has undertaken 13 prenatal diagnoses for Huntington’s disease from nine couples, whereas in the two years that we have been offering it we have had six requests for PGD for Huntington’s disease and three couples …. (shrink)

This work sets out to state and evaluate G. F. Stout’s views on concrete particular things, properties, universals, etc., and to develop some of the author’s own views concerning them. It is useful to have Stout’s position described in a single monograph, for his own statements are scattered. As D. M. Armstrong indicates in a foreword, Stout’s view that the properties of and relations between concrete things are particulars rather than universals is important as the main explicit statement of a (...) position which has had a kind of submerged existence in philosophy without much explicit advocacy, though I might note that Husserl comes nearer to it than one might expect if one only knows of him as a philosopher of essences. (shrink)

This work sets out to state and evaluate G. F. Stout’s views on concrete particular things, properties, universals, etc., and to develop some of the author’s own views concerning them. It is useful to have Stout’s position described in a single monograph, for his own statements are scattered. As D. M. Armstrong indicates in a foreword, Stout’s view that the properties of and relations between concrete things are particulars rather than universals is important as the main explicit statement of a (...) position which has had a kind of submerged existence in philosophy without much explicit advocacy, though I might note that Husserl comes nearer to it than one might expect if one only knows of him as a philosopher of essences. (shrink)

This is certainly one of the most beautiful books in philosophy published in the last couple of years. It comprises eighty-four essays, carefully selected, well-translated, covering almost the full range of Croce's immense literary production. Croce is certainly one of the most important and influential thinkers of this century and in this huge anthology the English-speaking reader is given an incomparable instrument to get acquainted with him. The list of the headings which classify the eighty-four essays are: The Logic of (...) Philosophy; Philosophical Criticism; Aesthetics; The Philosophy of Art and Language; The Theory of History; Economics and Ethics; Essays in Criticism and Literary History; Moral and Political History. But first one should read the late Cecil Sprigge's excellent introduction.—M. J. V. (shrink)

This is a work in speculative metaphysics in the grand manner. The type of absolute idealism Sprigge endeavors to vindicate is monistic panpsychism. This he does not only by means of detailed sustained argument but also by informed discussions, manifesting admirable erudition, of recent analytic philosophers such as Russell, Feigl, Quine, Armstrong, and Williams and of philosophers such as Spinoza, Leibniz, Berkeley, Hume, Kant, Fichte, Schopenhauer, Bradley, Royce, James, Santayana, Husserl, Whitehead, and Hartshorne.

An Important distinction between statements of fact and statements of value is widely recognised. Some philosophers are now saying that the distinction has been treated as more determinate than it is, but most philosophers would agree that the distinction is definite and important. The major contributions to Anglo-Saxon moral philosophy of this century have set out to illuminate the nature of this distinction. Ethical statements have been thevalue statements mainly at issue, but on the whole the aim has not been (...) to show wherein they differ from other value statements, but to show what distinguishes them in common with other value statements from factual statements. The characterisations of ethical statements which have become famous areones which if they apply to ethical statements at all apply equally to many other value statements as well. (shrink)

Bentham and Mill and probably most utilitarians have a good deal in common with Hobbes and Spinoza as moral thinkers. For they share a commitment to deriving ethics from the actual and normal motivitations of human beings as creatures of the natural world rather than, like Kant and many religious moralists, from some transcendent realm to the requirements of which natural man has a duty to submit without expecting any help therefrom in the satisfaction of his natural inclinations. In the (...) present context I shall call all such thinkers ethical naturalists, though I do not mean this expression in any very precise technical sense, only to indicate a commitment to somehow deriving morality from natural fact. (shrink)

ABSTRACT Some think we should look at aspects of what is commonly thought of as non‐sentient nature as having a value in themselves apart from the use or recreation they provide for humans or even animals. But to what extent does nature, in the character it presents to us, exist apart from presence to consciousness such as ours? Surely at least many of its aspects cannot. However, that does not stop them having a genuinely intrinsic value, just as works of (...) art do, whose existence also is impossible apart from their display to a consciousness such as ours. But can nature, as it exists quite apart from human or animal consciousness, have any intrinsic value? It is suggested that only a panpsychic, and perhaps pantheist, view of nature (a view for which there are excellent metaphysical grounds) can give a positive answer, and even that must be a very vague one [1]. (shrink)

When I perceive a physical object I am directly aware of something. This something may be called a sense?datum, leaving the question open whether it is indeed the physical object itself. Still, this question must be asked. It seems impossible that the sense?datum can be identical with the physical object for we do not always say we have different physical objects when we say we have different sense?data. On the other hand, the plain man does not think of the physical (...) object as something other than the sense?datum. It is suggested that the plain man regards the sense?datum as in a sense identical with the physical object he is perceiving. But it is a peculiar sense of ?identity? which is in question, one which does not conform to the rules logicians lay down for this word. (shrink)

Ethics education is recognized as an integral component of health professionals’ education and has been occurring in various guises in the curricula of health professional training in many countries since at least the 1970s. However, there are a number of different aims and approaches adopted by individual educators, programs, and, importantly, different health professions that may be characterized according to strands or trends in ethics education.

Utilitarian ethics and metaphysical idealism, especially of a Bradleyan sort, are not usually thought of as natural allies. Yet when one considers that it is a crucial part of utilitarian doctrine that the only genuine value is experienced value and almost the definition of idealism that for it the only genuine reality is experienced reality one should surely suspect that the two views have a certain affinity. The essential impulse behind utilitarianism is the sense that the only criterion of something (...) really being intrinsically good is that it feels good. To the ordinary man to say that something feels good is much the same as saying that it is a pleasure, so that for him it is a small step from identifying good with what feels good to identifying it with pleasure. It suggests itself, then, that the utilitarian is essentially one who thinks that, so far as the good goes, esse ispercipi. In that case the utilitarian is an idealist about value. It does not follow that he should be an idealist about things in general, but it does suggest the converse, that the idealist about things in general might be expected to be a utilitarian in his ethics. (shrink)

Bioethics, Volume 36, Issue 7, Page 765-773, September 2022.

Can philosophy offer reasonable grounds for the existence of a God possessing genuine religious significance and not proposed simply as the solution to a purely intellectual philosophical problem? Certainly many contemporary thinkers have insisted that no genuine religion could be based upon metaphysics. In this book, however, T. L. S. Sprigge examines sympathetically the most notable metaphysical systems of the last four centuries which purport to put religion on a rational footing and, after a thorough examination of their claims, considers (...) what kind of religious outlook they might support and how they actually affected the lives of their proponents. The thinkers studied include Spinoza, Hegel, T. H. Green, Bernard Bosanquet, Josiah Royce, A. N. Whitehead, and Charles Hartshorne, concluding with an exposition of the author's own viewpoint and a general discussion on the relation between metaphysics and religion. There is also a chapter on Kierkegaard as the most important critic of metaphysical religion. (shrink)

Writing from a scientifically and philosophically informed perspective, the authors provide a critical overview of the conceptual difficulties encountered in many current neuroscientific and psychological theories.