A compelling investigation into one of the most coveted and cherished ideals, "Wisdom" also chronicles the efforts of modern science to penetrate the mysterious nature of this timeless virtue.

The public debate over the ethics of cloning has been as thoughtful, and as sensational, as any in bioethics in recent years. Two essays bring us up to date. —Ed.

Since 1991, over half the states have enacted laws that restrict or prohibit insurers’ use of genetic information in pricing, issuing, or structuring health insurance. Wisconsin was the first state to do so, in 1991, followed by Ohio in 1993, California and Colorado in 1994, and then several more states a year in each of the next five years. Similar legislation has been pending in Congress for several years. Also, a 1996 federal law known as the Health Insurance Portability and (...) Accountability Act prohibits group health insurers from applying “preexisting condition” exclusions to genetic conditions that are indicated solely by genetic tests and not by any actual symptoms. (shrink)

Since 1991, over half the states have enacted laws that restrict or prohibit insurers’ use of genetic information in pricing, issuing, or structuring health insurance. Wisconsin was the first state to do so, in 1991, followed by Ohio in 1993, California and Colorado in 1994, and then several more states a year in each of the next five years. Similar legislation has been pending in Congress for several years. Also, a 1996 federal law known as the Health Insurance Portability and (...) Accountability Act prohibits group health insurers from applying “preexisting condition” exclusions to genetic conditions that are indicated solely by genetic tests and not by any actual symptoms. (shrink)

Reflexivity is a complex phenomenon. In this chapter, we are primarily interested in reflexivity insofar as it is a process of discovering for oneself and one’s audiences the perspectival features (e.g., background assumptions, social positions, and biases) that shape one’s judgments, decisions, and behaviors. So understood, reflexivity isn’t always a good idea. Sometimes thinking can get in the way of doing. (Downhill ski racing springs to mind.) But for some activities, such as action research, reflexivity is critical for doing the (...) activity well. While the value of reflexivity for action research is well understood, we believe that there is a form of reflexivity underappreciated in some research circles – philosophical reflexivity. In this chapter, we outline this form, argue for its importance in sound action research, and offer a technique, the Toolbox approach, for facilitating it. (shrink)

Nanomedicine is yielding new and improved treatments and diagnostics for a range of diseases and disorders. Nanomedicine applications incorporate materials and components with nanoscale dimensions where novel physiochemical properties emerge as a result of size-dependent phenomena and high surface-to-mass ratio. Nanotherapeutics and in vivo nanodiagnostics are a subset of nanomedicine products that enter the human body. These include drugs, biological products, implantable medical devices, and combination products that are designed to function in the body in ways unachievable at larger scales. (...) Nanotherapeutics andin vivonanodiagnostics incorporate materials that are engineered at the nanoscale to express novel properties that are medicinally useful. These nanomedicine applications can also contain nanomaterials that are biologically active, producing interactions that depend on biological triggers. Examples include nanoscale formulations of insoluble drugs to improve bioavailability and pharmacokinetics, drugs encapsulated in hollow nanoparticles with the ability to target and cross cellular and tissue membranes and to release their payload at a specific time or location, imaging agents that demonstrate novel optical properties to aid in locating micrometastases, and antimicrobial and drug-eluting components or coatings of implantable medical devices such as stents. (shrink)

Tom Phillips' painting for the dustjacket of the hardback edition of Metaphysics as a Guide to Morals depicts a faintly translucent, darkly-coloured, multi-layered lattice of letters, in which each character abuts directly upon others above, below and beside it, each overwrites or is overwritten by others of varying dimensions, but none is immediately decipherable as part of a word; and at the centre of this array is a geometrically precise, illuminated circle—perhaps emanating from a light located behind or under the (...) layers of letters, perhaps from one directed at them from above. This image is open to many interpretations. It could represent the sun from Plato's myth of the cave shining through the dialogue in which he presents it ; it could also represent the light of Miss Murdoch's attention playing over the palimpsest of texts that make up the Western tradition of metaphysical thought. But for anyone encountering it upon closing the book after a first reading, it may also seem very precisely to crystallize one's initial impression of that text. (shrink)

Two groups of researchers released the formal report of data for the human genome last Monday -- on the birthday of Charles Darwin, who jump-started our biological understanding of life's nature and evolution when he published ''The Origin of Species'' in 1859. On Tuesday, and for only the second time in 35 years of teaching, I dropped my intended schedule -- to discuss the importance of this work with my undergraduate course on the history of life. (The only other case, (...) in a distant age of the late 60's, fell a half-hour after radical students had seized University Hall and physically ejected the deans; this time at least, I told my students, the reason for the change lay squarely within the subject matter of the course!). (shrink)

Mr Jarvis, a Christian, was asleep in bed, dreaming of the Last Judgement. In his dream, Jarvis found himself seated next to God in a great cloud-swept hall. God had just finished handing down judgement on the drunkards, who were slowly shuffling out of the exit to the left. Angels were now ushering a group of nervous-looking men through the entrance to the right. As the men were assembled before Him, God began to speak.

The Fifth Annual Conference of the Hegel Society of Great Britain took place on September 15–16, 1983 in the delightful setting of St. Edmund Hall, Oxford. The theme of this year’s conference - “Hegel’s Dialectic” - was approached in a variety of ways by the contributors and provoked several lively and interesting discussions. The first paper of the conference was to have been given by Howard Williams, but unfortunately he had found his way to Pembroke College instead of St. (...) Edmund Hall and so was unable to begin the proceedings. The conference started therefore with a paper by John Llewelyn entitled “The Development of Dialectic from Kant to Hegel.”. (shrink)

The Sixth Annual Conference of the Hegel Society of Great Britain took place on September 13–14, 1984 at the same venue as the 1983 conference, St. Edmund Hall, Oxford. The topic for this year’s conference was “The Young Hegel,” and the papers covered various aspects of Hegel’s thought in the period before 1803.

In his list of essential reading, Richard Baxter includes a section on “affectionate practical English writers.” Among others, he mentions George Swinnock. While essentially forgotten today, Swinnock's contemporaries held him in high esteem as a skilful physician of the soul. The focus of this article is Swinnock's view of Scripture meditation as necessary for bridging the gap between head and heart in Christian experience. He encourages his readers to “retire out of the world's company, to converse with the word of (...) God.” He believes this “conversing” warms the heart, causing it to “boil with love” for God. With that basic premise in view, this article is organized around three main sections. The first establishes Swinnock's place in the Puritan meditative tradition, stretching back to Joseph Hall. The second analyzes Swinnock's faculty-focused approach to meditation, whereby it begins in the understanding, extends to the affections, and ends in the will, resulting in practical knowledge. The third section considers Swinnock's teaching on the role of the Holy Spirit in Scripture meditation. As with the other means of grace, meditation is ultimately dependent upon the Holy Spirit to work through it and along with it directly upon the faculties of the soul. The article concludes with Swinnock's threefold approach to transformative Scripture meditation. (shrink)

Jecker, et al., argue against rejecting a location for an international bioethics conference based on a “litmus test” for several reasons, ranging from the practical to the theoretical. However, th...

In 1277, Stephen Tempier, bishop of Paris, drafted the famous Condemnation of 219 articles in theology and natural philosophy. This Condemnation was a reaction against a group of theologians, led by Siger of Brabant, who were accused of holding that truths of reason could contradict those of revelation. Writing before the Condemnation, which impugned reason's autonomy, Thomas Aquinas critiqued Siger and his followers, and argued that reason could never generate truths that contradict revelation. As a consequence, Aquinas sometimes dwells (...) on reason's limits, terming our knowledge of God 'equivocal' or 'analogical'. Sitting on the other side of the Condemnation, around the turn of the fourteenth century, John Duns Scotus was concerned to secure for reason a portion of its lost dignity. Accordingly, he explores what we can know of God, and lays claim to 'univocal' knowledge of him. Some scholars hold that Scotus's claim to univocal knowledge of God puts him at odds with Aquinas. In this dissertation, I argue that this is not the case, that this apparent discord is largely the result of their different enterprises rather than their basic beliefs about our natural knowledge of God, that Scotus's discussion of univocity is targeted not at Aquinas, but rather at Henry of Ghent---the leading light of the University of Paris at the time that Scotus studied there---and that Scotus does not believe that our knowledge of God is univocal in a strong sense, such that he would claim that it is wholly accurate. Rather, Scotus believes that, in this life, our knowledge of God must comprise abstract concepts that can never do justice to their source. This being the case, he has more in common with Aquinas than some would allow. (shrink)

In this study, we set out to examine the role played by country institutional environments in explaining cross-country variation in the prevalence of women on corporate boards of directors. In order to address this question, we compare the predictive power and substantive implications of four existing typologies of national institutional environments due to Hall and Soskice (2001), La Porta et al., (1999), Weimar and Pape’s (1999), and Whitley (1991, 1996, 1999). These frameworks encapsulate a variety of national institutionalcharacteristics and (...) provide a means to a) evaluate the significance of national institutional environments for the presence of women on boards, and b) distinguish between the importance of various specific aspects of country institutional environments for board diversity. Our findings show that as much as half of the variation across countries in the presence of women on corporate boards is attributable to institutional factors and that legally-oriented institutions appear to play the most significant role in shaping board diversity. (shrink)

This paper asks whether geographically localised, or ‘hyperlocal’, uses of Twitter succeed in creating peer-to-peer neighbourhood networks or simply act as broadcast media at a reduced scale. Literature drawn from the smart cities discourse and from a UK research project into hyperlocal media, respectively, take on these two opposing interpretations. Evidence gathered in the case study presented here is consistent with the latter, and on this basis we criticise the notion that hyperlocal social media can be seen as a community (...) in itself. We demonstrate this by creating a network map of Twitter followers of a popular hyperlocal blog in Brockley, southeast London. We describe various attributes of this network including its average degree and clustering coefficient to suggest that a small and highly connected cluster of visible local entities such as businesses form a clique at the centre of this network, with individual residents following these but not one another. We then plot the locations of these entities and demonstrate that sub-communities in the network are formed due to close geographical proximity between smaller sets of businesses. These observations are illustrated with qualitative evidence from interviews with users who suggest instead that rather than being connected to one another they benefit from what has been described as ‘neighbourhood storytelling’. Despite the limitations of working with Twitter data, we propose that this multi-modal approach offers a valuable way to investigate the experience of using social media as a communication tool in urban neighbourhoods. (shrink)

Focusing on the plurality of irreconcilable conceptions of social and political justice, this book presents an array of new perspectives on the topic of distributive justice. Bringing together 30 original essays of well-established and young international scholars, the volume is essential reading for anyone interested in social and political justice.

As Nair-Collins and Joffe note, the concern that our tests for brain death do not successfully show that all brain functions have stopped is not new (Nair-Collins and Joffe 2023). As our abilities...

I agree fully that a “clearer picture of how vulnerability might manifest and how it can be accommodated, ideally without resorting to mere exclusion from research, is needed” (Friesen et al. 2023,...

Autonomous vehicles have the potential to save tens of thousands of lives, but legal and social barriers may delay or even deter manufacturers from offering fully automated vehicles and thereby cost lives that otherwise could be saved. Moral philosophers use “thought experiments” to teach us about what ethics might say about the ethical behavior of AVs. If a manufacturer designing an AV decided to make what it believes is an ethical choice to save a large group of lives by steering (...) away from the large group towards a single individual, could the manufacturer be liable to that single individual? I believe the answer is yes. This article discusses famous “trolley problem” thought experiments in moral philosophy, which news articles have recently applied to AVs. After establishing a hypothetical case, applying product liability law to AV behavior may show a way, in some jurisdictions, that will permit a manufacturer to implement an ethical choice without triggering liability, but liability risk remains. I then turn to possible traditional defenses to see if they prevent liability for a manufacturer making what it believes is an ethical design choice—necessity, defense of self, and the sudden emergency doctrine. None of them provides an effective defense. Under current law, maximizing collision avoidance appears to minimize legal risk. I conclude that the only way to provide effective protection to a manufacturer seeking to implement ethical choices about AV behavior is through special legislation or regulation. (shrink)

presents a puzzle as to whether Aristotle views morally virtuous activity as happiness, as book 1 seems to indicate, or philosophical contemplation as happiness, as book 10 seems to indicate. The most influential attempts to resolve this issue have been either monistic or inclusivist. According to the monists, happiness consists exclusively of contemplation. According to the inclusivists, contemplation is one constituent of happiness, but morally virtuous activity is another. In this essay I will examine influential defenses of monism. Finding these (...) accounts superior to inclusivism, but still deficient, I will present and defend a dualistic account of happiness in which two different types of happiness, one divine and one human, are present in Nicomachean Ethics. When Aristotle commends contemplation as a happiness that humans can attain, he is careful to specify that this activity corresponds to a capacity (nous) that is not, properly speaking, human, even though humans can exercise it. Contemplation, the divine good, is the highest good that humans can obtain, but it is not the characteristic human good. The characteristic human good corresponds to the specifically and merely human function, which is an activity of the compound of human reason and emotions. (shrink)

Winner of the Gustave O. Arlt Award in the HumanitiesThree understandings of the nature of religion--religion as experience, symbolic meaning, and power--have dominated scholarly discussions, in succession, for the past hundred years. Proponents of each of these three approaches have tended to downplay, ignore, or actively criticize the others. But why should the three approaches be at odds? Religion as it is practiced involves experiences, meanings, and power, so students of religion should attend to all three. Furthermore, theorists of religion (...) should have an account that carefully conceptualizes all three aspects, without regarding any of them as more basic than the others.Visions of Religion provides just such an account. Stephen S. Bush examines influential proponents of the three visions, arguing that each approach offers substantial and lasting contributions to the study of religion, although each requires revision.Bush rehabilitates the concepts of experience and meaning, two categories that are much maligned these days. In doing so, he shows the extent to which these categories are implicated in matters of social power. As for power, the book argues that the analysis of power requires attention to meaning and experience.Visions of Religion accomplishes all this by articulating a social practical theory of religion that can account for all three aspects, even as it incorporates them into a single theoretical framework. (shrink)

ABSTRACTTeam physicians have a complicated job that involves potentially conflicting obligations to multiple entities. Though responsible for the medical care of the athletes as individuals, they also have obligations to the team that employs them which can include returning athletes to play who are at heightened risk of re-injury. The fact that the athletes and owners have some overlapping interests only complicates this issue. Further, there are strong financial incentives to do what is necessary to obtain and keep a position (...) as a team physician. This article examines dual loyalty and conflict of interest in sports medicine, and argues that there is not now a widely accepted or adequate solution to either. Moving toward a solution will require fairly serious changes in the role of the team physician.Abbreviations: FIMS International Federation of Sports Medicine; NFL National Football League; MVP Most Valuable Player; RGIII Robert Griffin, III. (shrink)

The development of a code of ethics for a profession can be an indicator of the coherence and stability of a discipline as a unique and singular entity. Since “bioethics”, as a discipline, is not one profession but many, practiced by persons with not one but many varying responsibilities and training, it has been argued that no code of ethics is possible for the discipline(s) of bioethics. I argue that a code of ethics is possible for bioethics by looking at (...) the nature of the various disciplines and noting necessary overlap between them, and deriving the ethics from the nature of the discipline(s) themselves. I show how this can be done by arguing that strict rules about funding and conflict of interest are necessary for bioethicists. (shrink)

In this paper, I present and criticize two highly influential anti-skeptical proposals inspired by Wittgenstein’s (1969) remarks on ‘hinges’, namely Pritchard’s ‘hinge commitment strategy’ (2012, forthcoming a, forthcoming b) and Moyal-Sharrock ‘non epistemic strategy’ (2004,2005). I argue that both these proposals fail to represent a valid response to skeptical worries. Furthermore, I argue that following Wittgenstein’s analogy between ‘hinges’ and ‘rules of grammar’ we should be able to get rid of Cartesian skeptical scenarios as nonsensical, even if apparently intelligible, combination (...) of signs excluded from our epistemic practices. (shrink)

Despite considerable interest in viral evolution, at least among virologists, viruses are rarely considered from the same evolutionary vantage point as other organisms. Early work of necessity emphasized phenotype and phenotypic variation (and therefore arguably was more oriented towards the broader biological and ecological perspectives). More recent work (essentially since the development of molecular evolution in the 1960's but beginning earlier) has concentrated on genotypic variation, with less clarity about the significance of such variations. Other aspects of evolutionary theory, especially (...) considerations of natural selection and of evolutionary constraints, have not widely been applied to viruses, and an evolutionary framework for virology has long been lacking. This becomes apparent in considering 'emerging' viruses, which have often been treated on an ad hoc basis. It was often felt that, because previously unrecognized viruses are involved, mechanisms of viral emergence must mirror the unpredictability of mutations in the viral genome. However, most examples of viral emergence are independent of mutation, at least initially, and are often pre-existing viruses in changed circumstances ('viral traffic'). This conclusion also readily follows from ordinary Darwinian premises, which would require that, like other living species, 'new' organisms are descended only from existing species. In this respect, from a Darwinian perspective, viruses would appear to resemble other organisms. (shrink)

It is commonly assumed that persons who hold abortions to be generally impermissible must, for the same reasons, be opposed to embryonic stem cell research [ESR]. Yet a settled position against abortion does not necessarily direct one to reject that research. The difference in potentiality between the embryos used in ESR and embryos discussed in the abortion debate can make ESR acceptable even if one holds that abortion is impermissible. With regard to their potentiality, in vitro embryos are here argued (...) to be more morally similar to clonable somatic cells than they are to in vivo embryos. This creates an important moral distinction between embryos in vivo and in vitro. Attempts to refute this moral distinction, raised in the recent debate in this journal between Alfonso Gómez-Lobo and Mary Mahowald, are also addressed. (shrink)

William James argued for a philosophy of democracy and pluralism that advocates individual and collective responsibility for our social arrangements, our morality, and our religion. In James' view, democracy resides first and foremost not in governmental institutions or in procedures such as voting, but rather in the characteristics of individuals, and in qualities of mind and conduct. It is a philosophy for social change, counselling action and hope despite the manifold challenges facing democratic politics, and these issues still resonate strongly (...) today. In this book, Stephen Bush explores how these themes connect to James' philosophy of religion, his moral thought, his epistemology, his psychology, and his metaphysics. His fresh and original study highlights the relevance of James' thought to modern debates, and will appeal to scholars and students of moral and political philosophy. (shrink)

The constructivist position, that mystical experiences are determined by the experiencer's cultural context, is now more prevalent among scholars of religion than the perennialist position, which maintains that mystical experiences have a common core that is cross-culturally universal. In large part, this is due to the efforts of Wayne Proudfoot in his widely accepted book, Religious Experience.In this article, I identify some significant unresolved issues in Proudfoot's defence of constructivism. My aim is not to defend perennialism, but to specify some (...) objections to the constructivist thesis that constructivists need to address more adequately. (shrink)

Georges Bataille agrees with numerous Christian mystics that there is ethical and religious value in meditating upon, and having ecstatic episodes in response to, imagery of violent death. For Christians, the crucified Christ is the focus of contemplative efforts. Bataille employs photographic imagery of a more-recent victim of torture and execution. In this essay, while engaging with Amy Hollywood's interpretation of Bataille in Sensible Ecstasy, I show that, unlike the Christian mystics who influence him, Bataille strives to divorce himself from (...) any moral authority external to the ecstatic episode itself. I argue that in his attempt to remove external authority he abandons the only resources that could possibly protect his mystical contemplation from engendering sadistic attitudes. (shrink)

Makins’s analysis of the philosophical justification of decision-making understates and so misinterprets the importance of patient values to ‘the deference principle.’ (Makins N,1, p1) He assesses autonomy and beneficence as two separate arguments in support of deferring to patient preferences, but they only work well considered together. Further, neither the constitutive nor the evidential view of beneficence fully recognises the importance of patient values to understanding the patient’s worldview, which in turn determines what risks and benefits matter most. Revising these (...) arguments enables a much fuller understanding of the importance of patient values to the practice of medicine, which will in turn improve the refinement of the deference principle. Autonomy requires beneficence, and vice versa, for either of them to be sufficient arguments for deferring to patient choices. Focusing on autonomy alone to justify deference overstates the value of choice in and of itself, as good medicine does not pursue just any choices. It seeks informed consent, which means that the choices we truly value are those made while understanding what is importantly relevant to the choice. A well-informed decision includes data about expected side effects and likelihood of beneficial effects; but it also includes knowing the patient’s values and goals. One must know what is actually valuable …. (shrink)

An anxious resident paged ethics at 2:00 a.m. His patient, Mr. M, a twenty‐nine‐year‐old man with a history of multiple substance abuse, was in the hospital after cardiac arrest and lack of cerebral perfusion. Sadly, the young man probably met the criteria for brain death, but the final apnea test to confirm the diagnosis could not be done for another forty‐eight to seventy‐two hours because the Klonopin in his system might confound the results. The resident's concern, however, addressed a request (...) made by the patient's mother for a sperm harvest. The patient's mother maintained that her son had said he wanted to give her grandchildren. She wished to harvest sperm from him for a future use with an as‐yet‐to‐be‐determined surrogate mother. (shrink)

Jotkowitz, Glick, and Gesundheit (2008) rightly critique Manninen (2006) for an errant analysis of the Groningen protocol. However, they draw conclusions about the protocol itself that are not justified. Because of the nature of the care of infants, the Groningen protocol doesn't break new ethical ground. We already have to treat infants without direct access to their autonomous preferences or values; therefore, we are already making the decisions that Jotkowitz, Glick, and Gesundheit argue we are beginning to take once active (...) euthanasia of infants is allowed. (shrink)

In this reply to Kent Brintnall's response to my essay on Georges Bataille and the ethics of ecstasy, I explore two primary questions: whether instrumentalization is inherently violent and non-instrumentalization is inherently non-violent, and whether there is a way to intervene in the world that avoids both “apathetic disengagement” and domination. I endorse the view that instrumentalization can be good as well as bad, and I suggest that it is possible to strive to intervene in the world without striving to (...) master it. I make reference to Sarah Coakley as a Christian theologian who advances particular practices that aim for non-dominating intervention in theworld. (shrink)

William James is famous for his investigations of the “Varieties of Religious Experience” in which people encounter (what they take to be) the divine. But in his essay, “On a Certain Blindness in Human Beings,” his interest is in our experiences, not of anything purportedly supernatural, but of one another. He thinks we need to cultivate the capacity to apprehend the intrinsic value of others, even and especially of strangers. We do so in experiences of the wonder and beauty of (...) our fellow citizens, and of our harmony with them. Democratic societies require a sense of attraction to one another’s form of life if they are to inspire shared commitments to public goods. Whereas we shouldn’t reject the political significance of aversion, contestation, and dissonance, these negative attitudes do not suffice. Sustaining democratic engagement requires attractive attitudes, and among these are the wonder, beauty, and harmony that James promotes. (shrink)