Following Karni's seminal work, Walker and other researchers have recently provided gradually convincing evidence that sleep is critical for the consolidation-based enhancement (CBE) of motor sequence learning. Studies in our laboratory using a motor adaptation paradigm, however, show that CBE can also occur after the simple passage of time, suggesting that sleep effects on memory consolidation are task-related, and possibly dependent on anatomically dissociable circuits.

BackgroundResearch ethics and the measures deployed to ensure ethical oversight of research (e.g., informed consent forms, ethics review) are vested with extremely important ethical and practical goals. Accordingly, these measures need to function effectively in real-world research and to follow high level standards.MethodsWe examined approved consent forms for Magnetic Resonance Imaging (MRI) and functional Magnetic Resonance Imaging (fMRI) studies approved by Canadian research ethics boards (REBs).ResultsWe found evidence of variability in consent forms in matters of physical and psychological risk reporting. (...) Approaches used to tackle the emerging issue of incidental findings exposed extensive variability between and within research sites.ConclusionThe causes of variability in approved consent forms and studies need to be better understood. However, mounting evidence of administrative and practical hurdles within current ethics governance systems combined with potential sub-optimal provision of information to and protection of research subjects support other calls for more scrutiny of research ethics practices and applicable revisions. (shrink)

© 2017. The American Astronomical Society. All rights reserved.We present new observations of the low-mass companion to HD 984 taken with the Gemini Planet Imager as a part of the GPI Exoplanet Survey campaign. Images of HD 984 B were obtained in the J and H bands. Combined with archival epochs from 2012 and 2014, we fit the first orbit to the companion to find an 18 au orbit with a 68% confidence interval between 14 and 28 au, an eccentricity (...) of 0.18 with a 68% confidence interval between 0.05 and 0.47, and an inclination of 119°with a 68% confidence interval between 114°and 125°. To address the considerable spectral covariance in both spectra, we present a method of splitting the spectra into low and high frequencies to analyze the spectral structure at different spatial frequencies with the proper spectral noise correlation. Using the split spectra, we compare them to known spectral types using field brown dwarf and low-mass star spectra and find a best-fit match of a field gravity M6.5 ±1.5 spectral type with a corresponding temperature of K. Photometry of the companion yields a luminosity of log=2.88 ± 0.07 dex with DUSTY models. Mass estimates, again from DUSTY models, find an age-dependent mass of 34 ±1 to 95 ±4 M Jup. These results are consistent with previous measurements of the object. (shrink)

There is now compelling evidence that motor imagery (MI) promotes motor learning. While MI has been shown to influence the early stages of the learning process, recent data revealed that sleep also contributes to the consolidation of the memory trace. How such “online” and “offline” processes take place and how they interact to impact the neural underpinnings of movements has received little attention. The aim of the present review is twofold: i) providing an overview of recent applied and fundamental studies (...) investigating the effects of MI practice on motor learning, and ii) detangling applied and fundamental findings in support of a sleep contribution to motor consolidation after MI practice. We conclude with an integrative approach of online and offline learning resulting from intense MI practice in healthy participants, and underline research avenues in the motor learning/clinical domains. (shrink)

Human activity is permeated by norms of all sorts: moral norms provide the 'code' for what we ought to do, norms of logic regulate how we ought to reason, scientific norms set the standards for what counts as knowledge, legal norms determine what is lawfully permitted and what isn't, aesthetic norms establish canons of beauty and shape artistic trends and practices, and socio-cultural norms provide criteria for what counts as tolerable, just, praiseworthy, or unacceptable in a community or milieu. Given (...) the diversity of norm-governed phenomena prevailing in our everyday experience, it is not surprising that the question of normativity has recently generated important debates in philosophy. However, the more specific question concerning the nature and function of 'norms in perceptual experience' has received comparatively little attention. This volume brings together scholars from philosophy of mind, philosophy of perception, and phenomenology to explore this question. (shrink)

The main theme of Steve Crowell’s excellent Normativity and Phenomenology in Husserl and Heidegger is ‘the connection between normativity and meaning’ (p. 1), a central issue in both Husserl’s and...

Le présent essai porte sur la question de la place de la critique des religions en philosophie et dans l'espace public. C'est une discussion franche avec des philosophes québécois qui défendent la liberté de religion comme si cette liberté était la forme exemplaire des libertés fondamentales d'une société démocratique. Les croyances religieuses échappent-elles à la science? Est-il vraiment rationnel de croire que la nature est l'œuvre d'une intelligence surnaturelle? Pourquoi la croyance religieuse est-elle érigée en norme? Quelle est la place (...) de la religion à l'école? Peut-on dissocier la morale de la religion? Sans aller jusqu'à conclure que les religions doivent être éliminées ou que la science détient le monopole de la vérité, il ressort de cette analyse rigoureuse que l'attitude de traitement préférentiel des religions est injuste envers les non-croyants et qu'elle est en bonne partie la cause de la querelle sur la laïcité. " La position que défend ici Doyon est somme toute pérenne : sans aller jusqu'à remonter à Lucrèce et à quelques autres auteurs de l'Antiquité, elle est nettement celle qui se déploie à partir du Siècle des Lumières, et que diversement et de manière complémentaire formulent en France des gens comme Condorcet, D'Holbach, Buisson et d'autres. L'incontournable question que nous laisse ce bel ouvrage est dès lors de savoir s'il faut modifier cette position canonique ou si ce n'est pas plutôt pour s'en être éloigné que nous faisons aujourd'hui face aux difficultés qui sont les nôtres." – Normand Baillargeon, extrait de la préface. (shrink)

A leading critic of the disruptive force of technology in education, Bernard Stiegler saw the counter-effects of artificial intelligence in undermining human agency, autonomy and individuality, rendering the role of education ever more critical. Stiegler believes that our goal is not to abandon technology but to focus our attention on its power and direction in a hypercapitalist economy. While he did not foresee the emergence of generative artificial intelligence (GAI), its rapid acceleration raises important issues for his notion of digital (...) writing as a pharmakon. In this essay, we examine Stiegler’s view on intelligence, digital writing, technological memory, and neuropower, focusing specifically on his Shanghai lecture and Nanjing Lectures. We compare Stiegler with Catherine Malabou, who examines the nature of intelligence primarily through the lens of neuroscience. We argue that Malabou’s view of neuroplasticity in human and artificial brains, and her critique of techno-narcissism in the control over technology, add an important dimension to Stiegler’s political critique of education. Finally, we examine how best to construe AI as part of a hyper-materialist epistemology that Stiegler espouses in the conclusion of his Nanjing Lectures, to bring about neganthropic knowledge through a therapeutics of care. (shrink)

According to the fitting attitude (FA) analysis of value concepts, to conceive of an object as having a given value is to conceive of it as being such that a certain evaluative attitude taken towards it would be fitting. Among the challenges that this analysis has to face, two are especially pressing. The first is a psychological challenge: the FA analysis must call upon attitudes that shed light on our value concepts while not presupposing the mastery of these concepts. The (...) second challenge is normative: the FA analysis must account for the fittingness of the relevant attitudes in terms of a kind of normativity intimately related to these attitudes, but again without presupposing the mastery of the relevant value concepts. In this paper, we show that real progress is possible if we pay close attention to the nature of the attitudes recruited by the analysis. More specifically, we claim that an FA analysis that appeals to emotions conceived as evaluative attitudes — as opposed to, for instance, evaluative judgements or evaluative perceptions — has the best prospects of meeting the two challenges and of putting the FA analysis on a strong footing. (shrink)

Cet ouvrage interroge les articulations problématiques entre art, flux et contemporain, à partir de pratiques artistiques actuelles où interviennent le quotidien, le sociologique et le collectif. Traversé par des flux de toute sorte, le monde contemporain soulève la question de sa représentabilité, alors que les artistes ont, depuis toujours, éprouvé le besoin de se mettre en adéquation avec lui. Comment en effet montrer ce qui sans cesse se meut? Pourquoi suivre les mouvances du monde? Et finalement, que peut l'art d'aujourd'hui? (...) Il s'agit pour les artistes d'adopter une position de contemporanéité car toute observation du monde, fût-elle opérée sur un mode contemplatif, ne peut être l'objet de l'inactif et de l'inopérant. C'est pourquoi "devenir contemporain" est une nécessité, une injonction politique et éthique aussi bien qu'esthétique. Il nous faut dès lors entreprendre une "esthétique du contemporain", elle qui nous portera vers un "contemporain de l'esthétique" guidé par les flux et les devenirs. (shrink)

In this article, I side with those who argue that the debate about the definition of “disease” should be reoriented from the question “what is disease” to the question of what it should be. However, I ground my argument on the rejection of the naturalist approach to define disease and the adoption of a normativist approach, according to which the concept of disease is normative and value-laden. Based on this normativist approach, I defend two main theses: (1) that conceptual analysis (...) is not the right method to define disease and that conceptual engineering should be the preferred method and (2) that the method of conceptual engineering should be implemented following the principles of Alexandrova’s account of social objectivity in the context of the definition of disease. (shrink)

There is a traditional conception of knowledge but it is not the Justified True Belief analysis Gettier attacked. On the traditional view, knowledge consists in having a belief that bears a discernible mark of truth. A mark of truth is a truth-entailing property: a property that only true beliefs can have. It is discernible if one can always tell that a belief has it, that is, a sufficiently attentive subject believes that a belief has it if and only if it (...) has it. Requiring a mark of truth makes the view infallibilist. Requiring it to be discernible makes the view internalist. I call the view Classical Infallibilism. (shrink)

According to the fitting attitude (FA) analysis of value concepts, to conceive of an object as having a given value is to conceive of it as being such that a certain evaluative attitude taken towards it would be fitting. Among the challenges that this analysis has to face, two are especially pressing. The first is a psychological challenge: the FA analysis must call upon attitudes that shed light on our value concepts while not presupposing the mastery of these concepts. The (...) second challenge is normative: the FA analysis must account for the fittingness of the relevant attitudes in terms of a kind of normativity intimately related to these attitudes, but again without presupposing the mastery of the relevant value concepts. In this paper, we show that real progress is possible if we pay close attention to the nature of the attitudes recruited by the analysis. More specifically, we claim that an FA analysis that appeals to emotions conceived as evaluative attitudes — as opposed to, for instance, evaluative judgements or evaluative perceptions — has the best prospects of meeting the two challenges and of putting the FA analysis on a strong footing. (shrink)

One puzzle concerning highly idealized models is whether they explain. Some suggest they provide so-called ‘how-possibly explanations’. However, this raises an important question about the nature of how-possibly explanations, namely what distinguishes them from ‘normal’, or how-actually, explanations? I provide an account of how-possibly explanations that clarifies their nature in the context of solving the puzzle of model-based explanation. I argue that the modal notions of actuality and possibility provide the relevant dividing lines between how-possibly and how-actually explanations. Whereas how-possibly (...) explanations establish claims of possible explanations, how-actually explanations establish claims of actual ones. Models, in turn, simply provide evidence for these claims. (shrink)

It is undeniable that Thomas Aquinas showed great metaphysical originality among his contemporaries. However, his advances concerning the meaning of the uniqueness of the substantial form cannot be adequately grasped independently of an equally original understanding of matter, conceived in particular as pure power. This study attempts to grasp the implications of the Thomasian conception of matter in the various fields of his thought, from physics to metaphysics, passing through the foundations, in the very constitution of substance, theories of knowledge, (...) of moral action and apprehension of the beautiful. We discover a conception of the substance-subject in the strong sense which nevertheless shows itself, at the very heart of its constitutive principles, radically open to the originality of Otherness in its various forms. (shrink)

When spelled out properly infallibilism is a viable and even attractive view. Because it has long been summary dismissed, however, we need a guide on how to properly spell it out. The guide has to fulfil four tasks. The first two concern the nature of knowledge: to argue that infallible belief is necessary, and that it is sufficient, for knowledge. The other two concern the norm of belief: to argue that knowledge is necessary, and that it is sufficient, for justified (...) certainty. With such a guide in hand infallibilism can be evaluated on its own merits. The most controversial parts are the first and fourth. The idea that knowledge requires infallible belief is thought to be excessively sceptical. The idea that knowledge warrants certainty is thought to be excessively dogmatic. The present paper addresses the first. It argues that knowledge requires infallible belief. (shrink)

The emotions are at the centre of our lives and, for better or worse, imbue them with much of their significance. The philosophical problems stirred up by the existence of the emotions, over which many great philosophers of the past have laboured, revolve around attempts to understand what this significance amounts to. Are emotions feelings, thoughts, or experiences? If they are experiences, what are they experiences of? Are emotions rational? In what sense do emotions give meaning to what surrounds us? (...) -/- The Emotions: A Philosophical Introduction introduces and explores these questions in a clear and accessible way. The authors discuss the following key topics: -/- the diversity and unity of the emotions the relations between emotion, belief and desire the nature of values the relations between emotions and perceptions emotions viewed as evaluative attitudes the link between emotions and evaluative knowledge the nature of moods, sentiments, and character traits. -/- Including chapter summaries and guides to further reading, The Emotions: A Philosophical Introduction is an ideal starting point for any philosopher or student studying the emotions. It will also be of interest to those in related disciplines such as psychology and the social sciences. (shrink)

The revisionary approach to semantic paradox is commonly thought to have a somewhat uncomfortable corollary, viz. that, on pain of triviality, we cannot affirm that all valid arguments preserve truth (Beall2007, Beall2009, Field2008, Field2009). We show that the standard arguments for this conclusion all break down once (i) the structural rule of contraction is restricted and (ii) how the premises can be aggregated---so that they can be said to jointly entail a given conclusion---is appropriately understood. In addition, we briefly rehearse (...) some reasons for restricting structural contraction. (shrink)

This study examined the hypothesis that conditional reasoning involves visual short-term memory resources (Johnson-Laird, 1985). A total of 147 university students were given measures of verbal and visual short-term memory capacity and a series of concrete and abstract conditional reasoning problems. Results indicate that there is a positive correlation between verbal working memory capacity and reasoning with both concrete and abstract premises. A positive correlation was also obtained between visual working memory capacity and reasoning with concrete premises.

For Hannah Arendt, authority is the shape educational responsibility assumes. In our time, authority in Arendt’s sense is under pressure. The figure of Greta Thunberg shows the failure of adult generations, taken collectively, to take responsibility for the world and present and future generations of newcomers. However, in reflecting on Arendt’s use of authority, we argue that her account of authority also requires amendments. Arendt’s situating of educational authority in-between past and future adequately captures its temporal dimension. We make explicit (...) another, spatial, dimension: authority in-between world and earth. Arendt’s neglect of the material earth also has implications for the relational dimension of authority. Arendt’s authority depends on a dichotomy between the private and the public sphere. This is problematic. First, we agree with Arendt’s feminist critics that the personal can be made into the site of the political. Second, we point once more to Thunberg, the child, taking the public stage, thereby contesting the division between public and private. In response, we situate the relational dimension of authority in-between private and public. The three dimensions of educational authority taken together imply that it is situated in-between domains that cannot be reduced to each other or taken as absolutes: past and future, world and earth, and the private and public sphere. This brings us to our concept of ambiguous authority, which expresses the Arendtian nature of our reflections and the ways in which we seek to renew her original insights on educational authority. (shrink)

Widespread preservation of fossilized biomolecules in many fossil animals has recently been reported in six studies, based on Raman microspectroscopy. Here, we show that the putative Raman signatures of organic compounds in these fossils are actually instrumental artefacts resulting from intense background luminescence. Raman spectroscopy is based on the detection of photons scattered inelastically by matter upon its interaction with a laser beam. For many natural materials, this interaction also generates a luminescence signal that is often orders of magnitude more (...) intense than the light produced by Raman scattering. Such luminescence, coupled with the transmission properties of the spectrometer, induced quasi‐periodic ripples in the measured spectra that have been incorrectly interpreted as Raman signatures of organic molecules. Although several analytical strategies have been developed to overcome this common issue, Raman microspectroscopy as used in the studies questioned here cannot be used to identify fossil biomolecules. (shrink)

The phenomenon of species extinction raises more and more concern among ecologists facing the actual crisis of biodiversity. Scientific investigations of the causes and effects of extinction must be completed by a philosophical analysis of the concept of extinction that aims to clarify the meanings of the term ‘extinction’ and to analyse modalities, criteria and degrees of extinction. We will focus our attention on the apparent paradox of the possible ‘resurrection’ of species in the near future with the help of (...) genetic biotechnology and cloning techniques. The ontological background of the extinction concept is analysed in relation to the idea of species as classes. We will also show that there is no simple analogy between death and species extinction, and develop a conceptualist and dualistic system of supra-individual entities , supported by an instrumentalist approach to genetic manipulations which transform species into interactive kinds, which can go extinct and be recreated. (shrink)

While it is generally believed that justification is a fallible guide to the truth, there might be interesting exceptions to this general rule. In recent work on bridge-principles, an increasing number of authors have argued that truths about what a subject ought to do are truths we stand in some privileged epistemic relation to and that our justified normative beliefs are beliefs that will not lead us astray. If these bridge-principles hold, it suggests that justification might play an interesting role (...) in our normative theories. In turn, this might help us understand the value of justification, a value that's notoriously difficult to understand if we think of justification as but a fallible means to a desired end. We will argue that these bridge-principles will be incredibly difficult to defend. While we do not think that normative facts necessarily stand in any interesting relationship to our justified beliefs about them, there might well be a way of defending the idea that our justified beliefs about what to do won't lead us astray. In turn, this might help us understand the value of justification, but this way of thinking about justification and its value comes with costs few would be willing to pay. (shrink)

Sven Rosenkranz’s Justification as Ignorance shows how a strongly internalist conception of justification can be derived from a strongly externalist conception of knowledge, given an identification of justification with second-order ignorance and a set of structural principles concerning knowing and being in a position to know. Among these principles is an epistemic analogue of the Geach modal schema which states that one is always in a position to know that one doesn’t know p or in a position to know that (...) one doesn’t know not-p. Even suitably refined, the principle faces a range of counterexamples in which it misleadingly and persistently seems to one that one knows whether p without it seeming to one that one knows p nor that one knows not-p. These cases also threaten the book’s case for the luminosity of second-order ignorance, which is in turn central to its derivation of strongly internalist principles of justification. (shrink)

Knowledge-first evidentialism combines the view that it is rational to believe what is supported by one's evidence with the view that one's evidence is what one knows. While there is much to be said for the view, it is widely perceived to fail in the face of cases of reasonable error—particularly extreme ones like new Evil Demon scenarios (Wedgwood, 2002). One reply has been to say that even in such cases what one knows supports the target rational belief (Lord, 201x, (...) this volume). I spell out two versions of the strategy. The direct one uses what one knows as the input to principles of rationality such as conditionalization, dominance avoidance, etc. I argue that it fails in hybrid cases that are Good with respect to one belief and Bad with respect to another. The indirect strategy uses what one knows to determine a body of supported propositions that is in turn the input to principles of rationality. I sketch a simple formal implementation of the indirect strategy and show that it avoids the difficulty. I conclude that the indirect strategy offers the most promising way for knowledge-first evidentialists to deal with the New Evil Demon problem. (shrink)

Argumentation has been an important topic in knowledge representation, reasoning and multi-agent systems during the last twenty years. In this paper, we propose a new abstract framework where arguments are associated with a strength, namely a quantitative information which is used to determine whether an attack between arguments succeeds or not. Our Strength-based Argumentation Framework combines ideas of Preference-based and Weighted Argumentation Frameworks in an original way, which permits to define acceptability semantics sensitive to the existence of accruals between arguments. (...) The question of accruals arises in situations where several arguments defending the same position against another argument are unable to individually defeat this argument, but could do it collectively if they combine their strengths. We investigate some of the theoretical and computational properties of our new framework and semantics, and present a reasoning algorithm that is based on a translation of the problem into pseudo-boolean constraint satisfaction. This paper proposes an intuitive framework which allows strength compensations in an argumentation context where attacks may not succeed, completed by an approach which detects accruals throughout the reasoning process without requiring the elicitation of all compensatory combinations of arguments as an input. (shrink)

How can we use models to understand real phenomena if models misrepresent the very phenomena we seek to understand? Some accounts suggest that models may afford understanding by providing causal knowledge about phenomena via how-possibly explanations. However, general equilibrium models, for example, pose a challenge to this solution since their contribution appears to be purely mathematical results. Despite this, practitioners widely acknowledge that it improves our understanding of the world. I argue that the Arrow–Debreu model provides a mathematical how-possibly explanation (...) which establishes claims of mathematical dependence. The account developed reveals how mathematical knowledge can inform claims about the world, allow ‘what-if-things-had-been-different’ inferences, and thus improve our understanding. (shrink)

RNA polymerase II (RNAP II) non‐coding transcription is now known to cover almost the entire eukaryotic genome, a phenomenon referred to as pervasive transcription. As a consequence, regions previously thought to be non‐transcribed are subject to the passage of RNAP II and its associated proteins for histone modification. This is the case for the nucleosome‐depleted regions (NDRs), which provide key sites of entry into the chromatin for proteins required for the initiation of coding gene transcription and DNA replication. In this (...) review, recent data on the effects of pervasive transcription through NDRs are summarized and a model is proposed to explain how RNAP II‐driven transcription is able to modify the nucleosomes flanking the NDRs, leading to nucleosome repositioning and NDR closure. Even though much of the mechanistic detail underlying these events remains to be elucidated, such a model provides a basis to explain how non‐coding transcription through NDRs can regulate the initiation of coding gene expression and DNA replication. (shrink)

The ethics of safe sex in the gay community has, for many years, been focused on debates surrounding the responsibility regarding the use of condoms to prevent HIV transmission, once the only tool available. With the development of Truvada as a pre-exposure prophylaxis for HIV, for the first time in the history of the HIV/AIDS epidemic there is the potential to significantly reduce the risk of HIV transmission during sex without the use of condoms. The introduction of PrEP necessitates a (...) renewed discussion about the politics and ethics of safe sex for men who have sex with men. We present the arguments of authors who hold radically opposite positions with regard to the ethics of condom use by gay men, but who currently both criticize the use of PrEP. We offer a critique of their arguments and advance the position that the use of PrEP, even without condoms, can be acceptable and part of a safe sex ethics framework for MSM. (shrink)

We reformulate, in the context of continuous logic, an oscillation theorem proved by G. Hjorth and give a proof of the theorem in that setting which is similar to, but simpler than, Hjorth's original one. The point of view presented here clarifies the relation between Hjorth's theorem and first-order logic.

In this article, we present, assess and give reasons to reject the popular claim that shame is essentially social. We start by presenting several theses which the social claim has motivated in the philosophical literature. All of them, in their own way, regard shame as displaying a structure in which "others" play an essential role. We argue that while all these theses are true of some important families of shame episodes, none of them generalize so as to motivate the conclusion (...) that shame is an essentially social emotion. We consider each thesis in turn, explaining in the process their connections with one another as well as the constraints on a theory of shame they help uncover. Finally, we show how a non-social picture of shame is not only capable of meeting these constraints, but has the further virtue of shedding light on those situations in which others seem to play no role in why we feel shame. (shrink)

For the past two decades, philosophers of religion have paid close attention to the debates on public reason taking place within the context of political philosophy. Some thinkers claim that religious arguments should play a very limited role in political discourse, as this would amount to a politically sanctioned imposition of religious beliefs on people with different religious or non-religious worldviews. Others claim that excluding religious reasons would lead to an unfair exclusion of religious citizens from democratic processes. Underlying these (...) positions is a highly problematic idea of what it means to be a religious citizen. On the one hand, religious citizens are conceptualized as highly self-reflective theologians. Others instead imagine religious citizens to be wholly incapable of such self-reflection and of distinguishing between public and non-public spheres. In my article I attempt to criticize these underlying assumptions and point towards a more nuanced conception of the religious citizen. (shrink)

Models typically have actual, existing targets. However, some models are viewed as having non-actual targets. I argue that this interpretation comes at various costs and propose an alternative that fares better along two dimensions: (1) agreement with practice and (2) ontological and epistemological parsimony. My proposal is that many of these models actually have actual targets.