Two kinds of causal inference rules which are widely used by social scientists are investigated. Two conceptions of causation also widely used are explicated -- the INUS and probabilistic conceptions of causation. It is shown that the causal inference rules which link correlation, a kind of partial correlation, and a conception of causation are invalid. It is concluded a new methodology is required for causal inference.

Philosophers and scientists have maintained that causation, correlation, and "partial correlation" are essentially related. These views give rise to various rules of causal inference. This essay considers the "claims of several philosophers and social scientists for causal systems with dichotomous variables. In section 2 important commonalities and differences are explicated among four major conceptions of correlation. In section 3 it is argued that whether correlation can serve as a measure of A's causal influence on B depends upon the conception of (...) causation being used and upon certain background assumptions. In section 4 five major kinds of "partial correlation" are explicated, and some of the important relations are established among two conceptions of "partial correlation", the conception of "screening off", the conception of "partitioning", and the measures of causal influence which have been suggested by advocates of path analysis or structural equation methods. In section 5 it is argued that whether any of these five conceptions of "partial correlation" can serve as a measure of causal influence depends upon the conception of causation being used and upon certain background assumptions. The important conclusion is that each of the approaches (considered here) to causal inference for causal systems with dichotomous variables stands in need of important qualifications and revisions if they are to be justified. (shrink)

During the past decades several philosophers of science and social scientists have been interested in the problems of causation. Recently attention has been given to probabilistic causation in dichotomous causal systems. The paper uses the basic features of probabilistic causation to argue that the causal modeling approaches developed by such researchers as Blalock (1964) and Duncan (1975) can provide, when an additional assumption is added, adequate qualitative measures of one variableś causal influence upon another. Finally, some of the difficulties and (...) issues involved in developing adequate quantitative measures are discussed, and it is concluded that the causal modeling measures cannot provide adequate quantitative measures. (shrink)

Philosophers and scientists have maintained that causation, correlation, and partial correlation are essentially related. These views give rise to various rules of causal inference. This essay considers the claims of several philosophers and social scientists for causal systems with dichotomous variables. In section 2 important commonalities and differences are explicated among four major conceptions of correlation. In section 3 it is argued that whether correlation can serve as a measure of A's causal influence on B depends upon the conception of (...) causation being used and upon certain background assumptions. In section 4 five major kinds of partial correlation are explicated, and some of the important relations are established among two conceptions of partial correlation, the conception of screening off, the conception of partitioning, and the measures of causal influence which have been suggested by advocates of path analysis or structural equation methods. In section 5 it is argued that whether any of these five conceptions of partial correlation can serve as a measure of causal influence depends upon the conception of causation being used and upon certain background assumptions.The important conclusion is that each of the approaches (considered here) to causal inference for causal systems with dichotomous variables stands in need of important qualifications and revisions if they are to be justified. (shrink)

Two kinds of causal inference rules which are widely used by social scientists are investigated. Two conceptions of causation also widely used are explicated — the INUS and probabilistic conceptions of causation. It is shown that the causal inference rules which link correlation, a kind of partial correlation, and a conception of causation areinvalid. It is concluded anew methodology is required for causal inference.

In her paper entitled "Causal Laws and Effective Strategies" (1979), Cartwright sets out to establish the connection between laws of association and causal laws. In part Cartwright is trying to show the sense in which a cause increases the probability of its effect, and to explain what causal laws assert by giving an account of how causal laws are related to certain kinds of statistical laws. In section II we explicate the essential features of Cartwright's for- mulation and in section (...) III we argue that there are several reasons for believing that Cartwright's formulation is inadequate and must be rejected. Nonetheless, we believe Cartwright's formulation does contain two key insights into the nature of causation. In section IV we use these two insights to sketch out the key features of an alternative formulation that holds the certain laws of association are necessary conditions for causal laws. The alternative formu- lation, we believe, explains what it means to say a cause increases the probability of its effect. (shrink)

A contribution to a set of case studies, titled “In the Humanities Classroom,” this essay describes a course on the deep history of Italy developed for a “semester abroad” program in Perugia during the spring of 2016. It describes, in particular, two class meetings in the middle of the term that focused on the use of DNA, archaeology, and anthropology to study the lives of seven women who are the ancestors of almost every European today, as “imagined” by the geneticist (...) Bryan Sykes in his book The Seven Daughters of Eve. These women lived between forty-five hundred and ten thousand years ago—from the period when glaciers expanded to cover much of the northern hemisphere until the “Neolithic revolution,” when, in the wake of the glaciers' retreat, people turned permanently to farming. The student-led discussions, reconstructed here, of the lives of these women show the value of addressing questions of deep history in an international setting, where the intersections and disjunctions of the global and the local are especially evident. (shrink)

For over four decades, "Introduction to Operations Research" by Frederick Hillier has been the classic text on operations research. While building on the classic strengths of the text, the author continues to find new ways to make the text current and relevant to students. One way is by incorporating a wealth of state-of-the-art, user-friendly software and more coverage of business applications than ever before. The hallmark features of this edition include clear and comprehensive coverage of fundamentals, an extensive set (...) of interesting problems and cases, and state-of-the-practice operations research software used in conjunction with examples from the text. The ninth edition introduces a new partnership with the Institute for Operations Research and Management (INFORMS). These two pillars of the OR world have come together to showcase some of the award-winning applications of operations research and integrate them with this text. (shrink)

During the past decades several philosophers of science and social scientists have been interested in the problems of causation. Recently attention has been given to probabilistic causation in dichotomous causal systems. The paper uses the basic features of probabilistic causation to argue that the causal modeling approaches developed by such researchers as Blalock and Duncan can provide, when an additional assumption is added, adequate qualitative measures of one variableś causal influence upon another. Finally, some of the difficulties and issues involved (...) in developing adequate quantitative measures are discussed, and it is concluded that the causal modeling measures cannot provide adequate quantitative measures. (shrink)

Il contributo sostiene che una versione lunga e composita del Viaggio notturno del profeta e della sua ascensione, attribuita a Ibn ‘Abbas attraverso una figura più tarda conosciuta come al-Bakri, è diventata molto popolare e largamente diffusa nel tredicesimo secolo. Qui si propone una traduzione del viaggio celeste di Muhammad a partire da un importante manoscritto inedito di Istanbul copiato nella penisola araba verso la fine del tredicesimo secolo. Questa traduzione si propone come strumento per gli studiosi interessati alla tradizione (...) islamica delle ascensioni celesti e per chi si occupa delle possibile influenze musulmane sull’opera di Dante. Nonostante non si dimostri che Dante avesse avuto accesso diretto a questa fonte nel momento in cui componeva la divina commedia, ci sono prove sufficienti che le versioni di questo racconto fossero diffuse in diverse parti del Mediterraneo, prima e durante la vita di Dante. L’autore fa propria la recente ipotesi interpretativa di Bencheikh che sottolinea il ruolo fondamentale della versione di Bakri del Mi’râj per la composizione dell’ormai noto Libro della Scala, tradotto in latino e lingua francese antico in al-Andalus nella seconda metà del tredicesimo secolo.This article argues that a long and composite version of the narrative of Muhammad's night journey and ascension, one often ascribed to Ibn 'Abbas via a later figure known as al-Bakri, became especially popular and widely distributed in the thirteenth-century CE. It offers a translation of the Tour of Paradise section from a particularly important unpublished Istanbul manuscript preserving this version, copied in the Arabian peninsula near the end of the thirteenth-century. This translation could serve as a resource to scholars who are interested in the history of Islamic ascension narratives, and interested in the question of possible Muslim influences on Dante's Divine Comedy. While the author of this article does not argue that Dante must have been aware of this particular manuscript as he composed his masterwork, he claims that there is enough evidence to suggest that versions of this narrative circulated in different parts of the Mediterranean before and during Dante's lifetime. He supports the earlier conjecture by Bencheikh that the Bakri versions were likely foundational to the composition of the now famous "Book of Muhammad's Ladder" that was translated into Latin and Old French in al-Andalus / Spain in the second half of the thirteenth-century. (shrink)

The bacterial pathogen Listeria monocytogenes displays the remarkable ability to reorganize the actin cytoskeleton within host cells as a means for promoting cell‐to‐cell transfer of the pathogen, in a manner that evades humoral immunity. In a series of events commencing with the biosynthesis of the bacterial surface protein ActA, host cell actin and many actin‐associated protein self‐assemble to from rocket‐tail structures that continually grow at sites proximal to the bacterium and depolymerize distally. Widespread interest in the underlying molecular mechanism of (...) Listeria locomotion stems from the likelihood that the dynamic remodeling of the host cell actin cytoskeleton at the cell's leading edge involves mechanistically analogous interactions. Recent advances in our understanding of these fundamental cytoskeletal rearrangements have been achieved through a clearer recognition of the central role of oligo‐proline sequence repeats present in ActA, and these findings provide a basis for inferring the role of analogous host cell proteins in the force‐producing and position‐securing steps in pseudopod and lamellipod formation at the peripheral membrane. (shrink)