Commentary on Andrew Mitchell and Patricia Glazebrook on plants and agriculture in the context of Heidegger's own reflections on botany and technology in which I discuss, bees, cell phone radiation, the relatively complex but fairly obvious sociological dynamics of science and powerful commercial interests (capital), and mantid copulation.

Paper presented at the Heidegger Circle 2011. Although Aristotle’s influence on young Heidegger’s thought has been studied at length, such studies have almost exclusively focused on his interpretation of Aristotle’s ethics, physics and metaphysics. I will rather address Heidegger’s appropriation of Aristotle’s ontology of life. Focusing on recently published or recently translated courses of the mid 20’s (mainly SS 1924, WS 1925-26 and SS 1926), I hope to uncover an important aspect of young Heidegger’s thought left unconsidered: namely, that Dasein’s (...) existential structures – Befindlichkeit, Understanding and being-with-one-another through language – arose from his close reading of Aristotle’s ontology of life, of animal life. (shrink)

In 1935, A. G. Tansley, who was knighted later, proposed the ecosystem concept. Nevertheless, this concept was not without predecessors. Why did Tansley’s ecosystem prevail and not one of its competitors? The purpose of this article is to pin the distinguishing features of Tansley’s ecosystem down, as far as the published record allows. It is an exercise in finding the difference that made a difference. Besides being a pioneering ecologist, Tansley was an adept of psychoanalysis. His interest even led him (...) to visit Sigmund Freud in Vienna for a while. Psychologists had to regard the mind as an entity in its own right, while knowing that it truly was part of a larger whole (body + mind), because the causal relation between body and mind was unknown. This lead Tansley to conclude that psychologists must not objectify the system under study, have to search for causes within their own field, and must not speculate unless this serves a scientific purpose. In 1925, Tansley defended psychoanalysis in a prolonged controversy against a concerted attack criticizing its speculative content and poor scientific standing. This could have been the reason why Tansley kept his ecosystem free of speculative content and unscientific connotation. The competing ecosystem-like concepts, however, have contained philosophical speculation, non-deterministic properties like vitalism or entelechy, or have been burdened with unscientific connotations. Hence, rigorous restraint distinguished the ecosystem concept and made it ready for use by later researchers. (shrink)

Some Radical New Ideas About Consciousness Consciousness and the Cosmos: A New Copernican Revolution (forthcoming) Consciousness is our new frontier in modern science. Most scientists believe that it can be accomodated, explained, by existing scientific principles. I say that it cannot. That it calls all existing scientific principles into question. That consciousness is to modern science just exactly what light was to classical physics: All of our fundamental assumptions about the nature of Reality have to change. And I go on, (...) in this work,to spell out a whole new view of Reality, and of the Universe. And so, we'll have some fun! Modern science is already in deep trouble... Lorna Green. (shrink)

In this thesis, I argue that a good historical science will have the following characteristics: Firstly, it will seek to construct causal histories of the past. Secondly, the construction of these causal histories will utilise well-tested regularities of science. Additionally, well-tested regularities will secure the link between observations of physical traces and the causal events of interest. However, the historical sciences cannot use these regularities in a straightforward manner. The regularities must accommodate the idiosyncrasies of the past, and the degradation (...) of evidence over time. Through an examination of how the historical sciences work in practice, I show how they can confirm these unique causal histories, and the limits to their confirmatory strategies. (shrink)

We provide a methodology for the creation of ontological partitions in biomedicine and we test the methodology via an application to the phenomenon of blood pressure. An ontology of blood pressure must do justice to the complex networks of intersecting pathways in the organism by which blood pressure is regulated. To this end it must deal not only with the anatomical structures and physiological processes involved in such regulation but also with the relations between these at different levels of granularity. (...) For this purpose our ontology offers a variety of distinct partitions – of substances, processes and functions – and integrates these together within a single framework via transitive networks of part-whole and dependence relations among the entities in each of these categories. The paper concludes with a comparison of this methodology with the approaches of GOTM, KEGG, DIP and BIND and provides an outline of how the methodology is currently being applied in the field of biomedical database integration. (shrink)

Sydney Shoemaker, developing an idea of Wittgenstein’s, argues that we are immune to error through misidentification relative to the first-person pronoun. Although we might be liable to error when “I” (or its cognates) is used as an object, we are immune to error when “I” is used as a subject (as when one says, “I have a toothache”). Shoemaker claims that the relationship between “I” as-subject and the mental states of which it is introspectively aware is tautological: when, say, we (...) judge that “I feel pain,” we are tautologically aware that feels pain is instantiated and that it is instantiated in oneself. Moreover, he contends that this relationship holds not just for bodily sensations, but also for the sense of agency and for visual perception. But we deny that this relationship is tautological; instead, we treat Shoemaker’s principle (IEM) as a hypothesis. We then proceed to show that certain pathological states and experimentally-induced illusions can be adduced to show that IEM describes not a necessary relationship but a contingent relationship, one that sometimes fails to obtain. That we are not immune to error in the way Shoemaker describes has grave consequences for many aspects of his ideas concerning the first-person perspective. In the course of arguing that these empirical phenomena count against IEM, we also show that not only can the content of conscious experience be misrepresented, so too can the subject: that is, not only can the what of conscious experience be misrepresented, so too can the who. (shrink)

The primary impediment to formulating a general theory for adaptive evolution has been the unknown distribution of fitness effects for new beneficial mutations. By applying extreme value theory, Gillespie circumvented this issue in his mutational landscape model for the adaptation of DNA sequences, and Orr recently extended Gillespie's model, generating testable predictions regarding the course of adaptive evolution. Here we provide the first empirical examination of this model, using a single-stranded DNA bacteriophage related to phiX174, and find that our data (...) are consistent with Orr's predictions, provided that the model is adjusted to incorporate mutation bias. Orr's work suggests that there may be generalities in adaptive molecular evolution that transcend the biological details of a system, but we show that for the model to be useful as a predictive or inferential tool, some adjustments for the biology of the system will be necessary. (shrink)

Tumors, abscesses, cysts, scars, fractures are familiar types of what we shall call pathological continuant entities. The instances of such types exist always in or on anatomical structures, which thereby become transformed into pathological anatomical structures of corresponding types: a fractured tibia, a blistered thumb, a carcinomatous colon. In previous work on biomedical ontologies we showed how the provision of formal definitions for relations such as is_a, part_of and transformation_of can facilitate the integration of such ontologies in ways which have (...) the potential to support new kinds of automated reasoning. We here extend this approach to the treatment of pathologies, focusing especially on those pathological continuant entities which arise when organs become affected by carcinomas. (shrink)

The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.

Neither personal belief nor a phenomenal self model can exist without attachment to a pre-reflective core self.

Biological phenomena can be investigated at multiple levels, from the molecular to the cellular to the organismic to the ecological. In typical biology instruction, these levels have been segregated. Yet, it is by examining the connections between such levels that many phenomena in biology, and complex systems in general, are best explained. We describe a computation-based approach that enables students to investigate the connections between different biological levels. Using agent-based, embodied modeling tools, students model the microrules underlying a biological phenomenon (...) and observe the resultant aggregate dynamics. We describe 2 cases in which this approach was used. In both cases, students framed hypotheses, constructed multiagent models that incorporate these hypotheses, and tested these by running their models and observing the outcomes. Contrasting these cases against traditionally used, classical equation-based approaches, we argue that the embodied modeling approach connects more directly to students’ experience, enables extended investigations as well as deeper understanding, and enables “advanced” topics to be productively introduced into the high school curriculum. (shrink)