Abstract During the last decades it has become widely accepted that scientific observations are ?theory?laden?. Scientists ?see? the world with their theories or theoretical presuppositions. In the present paper it is argued that they ?see? with their scientific instruments as well, as the uses of scientific instruments is an important characteristic of modern natural science. It is further argued that Euclidean geometry is intimately linked to technology, and hence that it plays a fundamental part in the construction and operation of (...) scientific instruments. Finally, Euclidean geometry is compared to fractal geometry, and the question of its a priori status is raised. Although the position that Euclidean geometry is a priori in the original Kantian sense is untenable, the paper concludes that in some restricted sense Euclidean geometry may be said to be a priori. (shrink)

To one side of the wide third-floor hallway of Victoria College, just outside the offices of the Institute for the History and Philosophy of Science and Technology, lies the massive carcass of a 1960s-era electron microscope. Its burnished steel carapace has lost its gleam, but the instrument is still impressive for its bulk and spare design: binocular viewing glasses, beam control panel, specimen tray, and a broad work surface. Edges are worn, desiccated tape still feebly holds instructive reminders near control (...) dials; this was once a workhorse in some lab. But it exists now out of time and place; like many of the scientific instruments we study, it has not been touched by knowing hands in decades. (shrink)

What roles have instruments played in psychology and related disciplines? How have instruments affected the dynamics of psychological research, with what possibilities and limits? What is a psychological instrument? This paper provides a conceptual foundation for specific case studies concerning such questions. The discussion begins by challenging widely accepted assumptions about the subject and analyzing the general relations between scientific experimentation and the uses of instruments in psychology. Building on this analysis, a deliberately inclusive definition of what constitutes a psychological (...) instrument is proposed. The discussion then takes up the relation between instrumentation and theories, and differentiates in greater detail the roles instruments have had over the course of psychology’s history. Finally, the authors offer an approach to evaluating the possibilities and limitations of instruments in psychology. (shrink)

In psychiatry, pharmacological drugs play an important experimental role in attempts to identify the neurobiological causes of mental disorders. Besides being developed in applied contexts as potential treatments for patients with mental disorders, pharmacological drugs play a crucial role in research contexts as experimental instruments that facilitate the formulation and revision of neurobiological theories of psychopathology. This paper examines the various epistemic functions that pharmacological drugs serve in the discovery, refinement, testing, and elaboration of neurobiological theories of mental disorders. I (...) articulate this thesis with reference to the history of antipsychotic drugs and the evolution of the dopamine hypothesis of schizophrenia in the second half of the twentieth century. I argue that interventions with psychiatric patients through the medium of antipsychotic drugs provide researchers with information and evidence about the neurobiological causes of schizophrenia. This analysis highlights the importance of pharmacological drugs as research tools in the generation of psychiatric knowledge and the dynamic relationship between practical and theoretical contexts in psychiatry. (shrink)