Reconstructions of Romantic-era life science in general, and epigenesis in particular, frequently take the Kantian logic of autotelic “self-organization” as their primary reference point. I argue in this essay that the Kantian conceptual rubric hinders our historical and theoretical understanding of epigenesis, Romantic and otherwise. Neither a neutral gloss on epigenesis, nor separable from the epistemological deflation of biological knowledge that has received intensive scrutiny in the history and philosophy of science, Kant’s heuristics of autonomous “self-organization” in the third Critique (...) amount to the strategic capture of epigenesis from nature, for thought, in thought’s critical transcendence of nature. This essay looks to Jean-Baptiste Lamarck and his English contemporary Erasmus Darwin to begin to reconstruct the rigorously materialist, naturalist, and empiricist theories of epigenesis marginalized by Kantian argumentation. As theorists of environmental and social collaboration in the ontogeny of viable forms, Lamarck and Darwin illuminate features of our own epigenetic turn obscured by the rhetoric of “self-organization,” allowing us to glimpse an alternative Romantic genealogy of the biological present. (shrink)

Johann Friedrich Blumenbach is widely known as the father of German vitalism and his notion of Bildungstrieb, or nisus formativus, has been recognized as playing a key role in the debates about generation in German-speaking countries around 1800. On the other hand, Caspar Friedrich Wolff was the first to employ a vitalist notion, namely that of vis essentialis, in the explanatory framework of epigenetic development. Is there a difference between Wolff’s vis essentialis and Blumenbach’s nisus formativus? How does this difference (...) influence their overall understanding of the epigenetic process? The paper aims to provide an answer to these questions through the analysis of a little-known document, which contributes to shed light on a crucial chapter of the German life sciences in the late eighteenth-century, namely the decisive phase of the process that led to the formalization of biology as a unified field of inquiry at the beginning of the nineteenth century. (shrink)

Biologists explain organisms’ behavior not only as having been programmed by genes and shaped by natural selection, but also as the result of an organism’s agency: the capacity to react to environmental changes in goal-driven ways. The use of such ‘agential explanations’ reopens old questions about how justified it is to ascribe agency to entities like bacteria or plants that obviously lack rationality and even a nervous system. Is organismic agency genuinely ‘real’ or is it just a useful fiction? In (...) this paper we focus on two questions: whether agential explanations are to be interpreted ontically, and whether they can be reduced to non-agential explanations (thereby dispensing with agency). The Kantian approach we identify interprets agential explanations non-ontically, yet holds agency to be indispensable. Attributing agency to organisms is not to be taken literally in the way we attribute physical properties such as mass or acceleration, but nor is it a mere heuristic or predictive tool. Rather, it is an inevitable consequence of our own rational capacity: as long as we are rational agents ourselves, we cannot avoid seeing agency in organisms. (shrink)

While Kant introduces his critical philosophy in continuity with the experimental tradition begun by Francis Bacon, it is widely accepted that his Copernican revolution places experimental physics outside the bounds of science. Yet scholars have recently contested this view. They argue that in Critique of the Power of Judgment Kant’s engagement with the growing influence of vitalism in the 1780s leads to an account of nature’s formative power that returns experimental physics within scientific parameters. Several critics are sceptical of this (...) revised reading. They argue that Kant’s third Critique serves precisely to deflate the epistemological status of experimental physics, thereby protecting science from the threat of vitalism. In this paper I examine Kant’s account of science in the context of the experimental tradition of philosophy, particularly in relation to the generation dilemma of the eighteenth century. I argue that Kant does not deflate the epistemological status of experimental physics but rather introduces systematicity to the experimental tradition. By identifying the reflective use of reason to organize laws of experience into a systematic whole, Kant aims to ground experimental inquiry on the secure course of a science, opening a conception of science as a research programme. (shrink)