This article critically examines one of the most prevalent metaphors in modern biology, namely the machine conception of the organism (MCO). Although the fundamental differences between organisms and machines make the MCO an inadequate metaphor for conceptualizing living systems, many biologists and philosophers continue to draw upon the MCO or tacitly accept it as the standard model of the organism. This paper analyses the specific difficulties that arise when the MCO is invoked in the study of development and evolution. In (...) developmental biology the MCO underlies a logically incoherent model of ontogeny, the genetic program, which serves to legitimate three problematic theses about development: genetic animism, neo-preformationism, and developmental computability. In evolutionary biology the MCO is responsible for grounding unwarranted theoretical appeals to the concept of design as well as to the interpretation of natural selection as an engineer, which promote a distorted understanding of the process and products of evolutionary change. Overall, it is argued that, despite its heuristic value, the MCO today is impeding rather than enabling further progress in our comprehension of living systems. (shrink)

Godfrey-Smith ( 2001 ) has distinguished three types of adaptationism. This article builds on his analysis, and revises it in places, by distinguishing seven varieties of adaptationism. This taxonomy allows us to clarify what is at stake in debates over adaptationism, and it also helps to cement the importance of Gould and Lewontin’s ‘Spandrels’ essay. Some adaptationists have suggested that their essay does not offer any coherent alternative to the adaptationist programme: it consists only in an exhortation to test adaptationist (...) hypotheses more thoroughly than was usual in the 1970s. Here it is argued that the ‘Spandrels’ paper points towards a genuinely non-adaptationist methodology implicit in much evolutionary developmental biology. This conclusion helps to expose the links between older debates over adaptationism and more recent questions about the property of evolvability. (shrink)

Evolutionary psychologists, among others, have used a method called “reverse engineering” to uncover ( a ) whether a trait was selected for, and ( b ) if so, why that trait was selected for. In this paper I argue that reverse engineering cannot deliver on either ( a ) or ( b ), and tends to pervert, rather than enhance, our knowledge of natural history. In particular, I expose as false a fundamental assumption of reverse engineering—namely, that all traits selected (...) for a particular function will share some nontrivial properties. *Received March 2006; revised June 2008. †To contact the author, please write to: Department of Philosophy, 229 Major Williams Hall (0126), Virginia Tech, Blacksburg, VA 24061; e‐mail: [email protected]. (shrink)

Inspired by the success of synthesising organic substances by Friedrich Wöhler in 1828, the vision of creating life in the laboratory synthetically has become increasingly accessible for today’s synthetic biology and synthetic genomics, respectively. The engineering of biology – a contemporary version of the liaison of technology and organic form – creates cellular machines, biobricks, biomolecular ‘borgs’, and entire synthetic genomes of artificial organisms. Besides major ethical concerns, the shift in scientific epistemology is of interest. Unlike classical analytical science, synthetic (...) science understands by a process of generation, through which myriads of new things are created, dramatically changing the living environment. (shrink)

Comparing engineering to evolution typically involves adaptationist thinking, where well-designed artifacts are likened to well-adapted organisms, and the process of evolution is likened to the process of design. A quite different comparison is made when biologists focus on evolvability instead of adaptationism. Here, the idea is that complex integrated systems, whether evolved or engineered, share universal principles that affect the way they change over time. This shift from adaptationism to evolvability is a significant move for, as I argue, we can (...) make sense of these universal principles without making any adaptationism claims. Furthermore, evolvability highlights important aspects of engineering that are ignored in the adaptationist debates. I introduce some novel engineering examples that incorporate these key neglected aspects, and use these examples to challenge some commonly cited contrasts between engineering and evolution, and to highlight some novel resemblances that have gone unnoticed. (shrink)

This dissertation focuses on teleology and functions in biology. More precisely, it focuses on the scientific legitimacy of teleofunctional attributions and explanations in biology. It belongs to a multi-faceted debate that can be traced back to at least the 1970s. One aspect of the debate concerns the naturalization of functions. Most authors try to reduce, translate or explain functions and teleology in terms of efficient causes so that they find their place in the framework of the natural sciences. Our approach (...) here is radically different, as we question the premise that teleological explanations are disguised causal explanations. On the contrary, we defend that they are acceptable in natural sciences and in biology in particular. We challenge the idea that teleological explanations are immature causal explanations, as well as the idea that teleology and functions are some sort of intentional explanations. We therefore reject the accusations of anthropomorphism, vitalism and finalism. On the contrary, we defend that teleology, causality and intentionality correspond to different, autonomous and complementary modes of representation of the outside world. -/- ———[FRANÇAIS]——— -/- Ce travail de thèse porte sur la téléologie et les fonctions en biologie. Plus précisément, il porte sur la légitimité scientifique des attributions et des explications téléofonctionnelles en biologie. Il s’inscrit dans le cadre d’un débat à plusieurs facettes que l’on peut faire remonter au moins jusqu’aux années 1970 et qui est encore très actif aujourd’hui. L’un des aspects du débat porte sur la naturalisation des fonctions, c’est-à-dire sur la manière de les réduire, de les traduire ou de les expliciter en termes de causes efficientes de sorte qu’elles trouvent leur place dans le cadre des sciences de la nature. Notre approche ici est radicalement différente, car nous remettons en question la prémisse selon laquelle les explications téléologiques seraient des explications causales déguisées. Nous défendons au contraire qu’elles sont acceptables en tant que telles aussi bien de façon générale que dans le domaine scientifique et en particulier en biologie. De façon générale, nous remettons en question l’idée selon laquelle la pensée téléologique serait une pensée causale immature, ainsi que sa dépendance présumée vis-à-vis de la psychologie, c’est-à-dire de l’intentionnalité. Nous rejetons donc les accusations d’anthropomorphisme, de vitalisme et de finalisme formulées contre elle. Nous défendons au contraire que la téléologie, la causalité et l’intentionnalité correspondent à des modes différents, autonomes et complémentaires de représentation du monde extérieur. (shrink)

We develop a new metaphor account where metaphors become surrogate variables for different but related phenomena. As we will argue, subrogation is the result of the interplay between the things inspired by the metaphor and the empirical dynamics that result from such inspiration. In particular, we focus on adaptive radiation, a major concept of evolutionary biology. Our study suggests that there is no distinct phenomenon, process, or pattern in nature than can be identified as adaptive radiation. What we have instead (...) is a grouping variable that has surrogated different evolutionary phenomena into one expansive label. We believe this analysis of metaphors helps better understand the value of metaphors for science not only as a provider of epistemic and cognitive virtues but most importantly, as a crucial research tool that can both help and divert scientific experimentation. (shrink)

The evolutionary psychologist Geoffrey Miller has argued that various features of human psychology have been sculpted, at least in part, by the evolutionary process of sexual selection via mate choice. This paper specifically examines the central claim of Miller’s account, namely that certain cognitive traits have evolved to function as good genes fitness indicators. First, I expound on and clarify key foundational concepts comprising the focal hypothesis, especially condition-dependence, mutation target size, and mutation-selection balance. Second, I proceed to highlight some (...) subtle distinctions with respect to the concepts of exaptation and adaptation, as well as Fisherian runaway selection and good genes sexual selection, all of which in turn bear importantly on the overall framework of cognitive traits as fitness indicators. Third and finally, I close out the paper by examining various conceptual and methodological criteria which are integral to identifying sexually selected adaptations, then briefly examine some empirical work that has aimed to test the hypothesis that traits such as humor and creativity function as sexually attractive fitness indicators. (shrink)

Segundo Daniel Dennett insistiu em diferentes trabalhos, o programa adaptacionista darwiniano constitui uma legítima e insubstituível translação da perspectiva intencional ao domínio da biologia. Mas, para que essa tese possa ser formulada com toda clareza, e não fique no plano da simples metáfora – coisa que não é o objetivo de Dennett – é necessário esclarecer qual seria o sistema intencional cujo comportamento estudamos conforme essa perspectiva. Assim, e contra a alternativa escolhida pelo próprio Dennett, e retomando uma proposta do (...) Karl Popper, sustentaremos que esse sistema não é a natureza como um tudo, mas sim o sistema constituído por uma população ou uma linhagem de organismos: eles são os agentes dos processos adaptativos. Não é nossa meta, entretanto, contradizer as teses centrais da Dennett; mas sim as reforçar.How do species think? Daniel Dennett has insisted in different occasions that Darwin’s Adaptationist Program constitutes a legitimate and hardly displaceable translation of the intentional point of view in the Biology field. However, in order for us to be able to state this thesis clearly and to avoid getting into the domain of mere metaphor – which is not Dennett’s purpose -, we have to single out what intentional system the behaviour of which we study on such a perspective. That being noted, we shall argue, contrary to the alternative that Dennett himself picked out, and close to Karl Popper’s suggestion, that such a system is not nature as a whole, but the system made up by a population or a class of organisms: those are the agents of the adaptative processes. We do not, however, aim at contradicting Dennett’s overall strategy; rather, we aim at reinforcing it. (shrink)