My aim in this chapter is to survey some of the most important developments in thinking about essence in the early modern period, highlighting ways in which thinkers in the period gradually depart from the medieval Aristotelian tradition. In this tradition, essence is thought of as selective, explanatory, and kind-determining. Whereas in the beginning of the early modern period some figures (such as René Descartes, Thomas Hobbes, Margaret Cavendish, and Anne Conway) still adhere to this traditional view, later figures (including (...) Benedict de Spinoza, G.W. Leibniz, and John Locke) reject it. (shrink)