Throughout the sixteenth century, learned physicians across Europe performed a diverse array of “trials” of phenomena and published reports about them. This essay traces the phrase “periculum facere” (“to make a trial”) and related terms through natural history investigations, drug testing, chymical analysis, and anatomical discoveries. Physicians used ancient precedents, their learned expertise, and pedagogical authority to anchor the epistemic status of their trials and incorporated the historical narratives of their trial-making within arguments to factual and causal knowledge, even philosophical (...) scientia. Developed from engagement with things, ancient texts, other healers, and students, this lively tradition of contrived, first-person empirical trials flourished in some academic institutions, especially the University of Padua. The frequency and visibility of sixteenth-century medical trials, especially in the education of hundreds of students annually, is essential evidence for understanding how experimentation came to be widespread in early modern Europe. (shrink)

In 1622, Francis Bacon published his Historia naturalis et experimentalis. Many of the features of Bacon's natural and experimental histories were entirely new. This paper studies this literary form as a new epistemic genre. In particular, it analyzes its origin and evolution in Bacon's work, focusing on how its basic template and features were influenced by his specific epistemic requirements. It shows that Bacon devised these features in the process of developing a Historia mechanica, or a history of the mechanical (...) arts, drawing on the particular case of the technical recipe. Since antiquity, the recipe had been the dominant epistemic genre for recording and communicating technical knowledge. However, this paper suggests that the recipe format did not meet Francis Bacon's epistemic needs. In particular, the format was incompatible with the goal of keeping experimentation and its reporting open-ended and flexible. More generally, the acknowledgment of the provisional, historical character of knowledge was a tenet of what Bacon called an “initiative” method of knowledge transmission, or a method of “probation.” According to this approach, knowledge “ought to be delivered and intimated, if it were possible, in the same method wherein it was invented” and discovered. Only the display of its tentative features would encourage and stimulate others to improve and advance it. The format of the new genre of natural and experimental histories grew out of Bacon's dissatisfaction with the way in which recipes hid the imperfection of the process of knowledge production. (shrink)

When we examine the history of astronomy up to the end of the seventeenth century by considering the relation between mathematical astronomy and natural philosophy, it has been argued that there were two groups of philosophers and astronomers: instrumentalists and realists. However, this classification is deficient when we consider attitudes toward the explanatory power of mathematics in determining astronomical theories. I offer the solution of dividing realists into two subcategories—mathematical realists and physical realists. Mathematical realists include those who thought mathematics (...) could provide the real motions of celestial bodies. The physical realists, who include Ibn Rushd (Averroës), believed mathematics could not provide us with the real structure of the heavens. To avoid contradictions between the physical and mathematical models, the physical realists held that a mathematical model of the heavens should be designed by considering physics. I argue, in this article, that Francis Bacon can be considered a physical realist. (shrink)