Chemistry possesses a distinctive theoretical lens—a distinctive set of theoretical concerns regarding the dynamics and transformations of a perplexing variety of organic and nonorganic substances—to which it must be faithful. Even if it is true that chemical facts bear a special (reductive) relationship to physical facts, nonetheless it will always still be true that the theoretical lenses of the two disciplines are distinct. This has consequences for how chemists pursue their research, as well as how chemistry should be taught.