Abstract
A dose of diprenorphine, which produces no analgesia, antagonizes the analgesia of other opioids, and facilitates pressing for brain stimulation in rats, was shown to establish a conditioned place preference. This finding provides further support for the conclusion that opioid analgesia and the positive reinforcing characteristics of opioids are separable.
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This research was supported by New York State Health Research Council Grant HRC 13-109. We would like to thank Gaylene Reichert-Hunter, Brian Stanton, Alice Lindsay, and Jean Bestle for their aid in completing this project.
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Beaman, C.M., Hunter, G.A. & Reid, L.D. Diprenorphine, an antagonist of opioid analgesia, elicits a positive affective state in rats. Bull. Psychon. Soc. 22, 354–355 (1984). https://doi.org/10.3758/BF03333841
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DOI: https://doi.org/10.3758/BF03333841