Abstract
Synthetic biology is a new biotechnology that is developing at an impressive pace and attracting a considerable amount of attention from outside the scientific community as well. In this article, two main philosophically and ethically relevant characteristics of this field of research will be laid bare, namely its reliance on mechanistic metaphors to denominate simple forms of life and its appeal to the semantic field of creativity. It is argued that given these characteristics synthetic biology can be understood as a prime example of a kind of human interference with reality that German philosopher Hannah Arendt called “fabrication.” This kind of self-world-relation contrasts to “action,” a relation that introduces, among other things, the idea of an inherent value of the object acted upon. Taking up this latter perspective, one scientific and two ethical challenges to synthetic biology’s take on the realm of life are identified.
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References
Anders G (1980) Die Antiquiertheit des Menschen, Band II. Über die Zerstörung des Lebens im Zeitalter der dritten industriellen Revolution. Beck, Munich
Arendt H (1998) The human condition. University of Chicago Press, Chicago
Bedau MA (2011) The intrinsic scientific value of reprogramming life. Hastings Cent Rep 41:29–31
Benner SA (2003) Synthetic biology: act natural. Nature 6919:118
Boldt J, Müller O (2008) Newtons of the leaves of grass. Nat Biotechnol 26:387–389
Feature News (2009) What’s in a name? Nat Biotech 27:1071–1073
Gibson DG, Glass JI, Lartigue C, Noskov VN, Chuang RY, Algire MA et al (2010) Creation of a bacterial cell controlled by a chemically synthesized genome. Science 5987:52–56
Habermas J (2003) The future of human nature. Polity, Cambridge
Jonas H (2001) The phenomenon of human life. Toward a philosophical biology. Northwestern University Press, Evanston
Kwok R (2010) Five hard truths for synthetic biology. Nature 7279:288–290
Morange M (2009) Synthetic biology. A bridge between functional and evolutionary biology. Biological Theory 4:368–377
Presidential Commission for the Study of Bioethical Issues (2010) New directions. The ethics of synthetic biology and emerging technologies. http://bioethics.gov/cms/sites/default/files/PCSBI-Synthetic-Biology-Report-12.16.10.pdf. Accessed 16 Feb 2013
Schmidt M (2009) Do I understand what I can create? Biosafety issues in synthetic biology. In: Schmidt M, Kelle A, Ganguli A, de Vriend H (eds) Synthetic biology. The technoscience and its societal consequences. Springer Academic Publishing, Heidelberg, pp 81–100
Sennett R (2008) The craftsman. Yale University Press, New Haven
Silver LM (2007) Life 2.0. Newsweek International, June 4
Acknowledgments
I acknowledge the support of the German Federal Ministry of Education and Research (Joint ELSI research project “Synthetic Biology,” 01GP1003A).
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Boldt, J. Life as a Technological Product: Philosophical and Ethical Aspects of Synthetic Biology. Biol Theory 8, 391–401 (2013). https://doi.org/10.1007/s13752-013-0138-7
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DOI: https://doi.org/10.1007/s13752-013-0138-7