Neurobiology of Stress : New Vistas
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1
Université de Tours, INRA CNRS, France
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2
Sultan Moulay Slimane University, Fac Sciences and Techniques, Life Sciences, Morocco
Stress responses are elicited by a variety of stimuli and are aimed at counteracting direct or perceived threats to the well being of an organism. In the mammalian central and peripheral nervous systems, specific cell groups provide signaling circuits that indicate the presence of a stressor and elaborate an adequate response, ultimately restoring homeostasis. Many signaling systems, such as CRH or CART, could modulate the responses of the hypothalamopituitaryadrenal (HPA) axis and the sympathoadrenal system, suggesting that they may have a role in the regulation of the neuroendocrine and autonomic responses during stress. Subsequently, stress interferes with normal and pathological processes including addiction. In some cases, the organism fails to counteract stress; this can lead to the disturbance of several processes like neurogenesis, or to a pathological state like depression. This in general depends on the stress paradigm and its severity. The role of each stress paradigm (mild vs strong) in the generation of these negative effects and the neuronal circuitry involved will be discussed in view of novel data and literature.
Keywords:
Stress, Psychological,
stress paradigms,
Neurogenesis,
Water Deprivation,
Chronic mild stress
Conference:
4th Conference of the Mediterrarnean Neuroscience Society, Istanbul, Türkiye, 30 Sep - 3 Oct, 2012.
Presentation Type:
Symposium
Topic:
Abstracts
Citation:
Moyse
E and
Najimi
M
(2013). Neurobiology of Stress : New Vistas.
Conference Abstract:
4th Conference of the Mediterrarnean Neuroscience Society.
doi: 10.3389/conf.fnhum.2013.210.00053
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Received:
31 Mar 2013;
Published Online:
11 Apr 2013.
*
Correspondence:
Prof. Mohamed Najimi, Sultan Moulay Slimane University, Fac Sciences and Techniques, Life Sciences, Beni Mellal, Morocco, mnajimi1@fstbm.ac.ma