Abstract
The effect of septal lesions on consumption of a sucrose solution containing 4.75% ethanol was assessed using two-bottle and one-bottle tests. Septal and control rats showed very similar levels of alcohol consumption in both tests. During two-bottle testing, both groups demonstrated a clear preference for sucrose solution. During the 15-min one-bottle test, alcohol intake was substantial (means = 2.93 and 2.95 ml/kg) and produced obvious symptoms of inebriation. It is concluded that self-administration of ethanol under these conditions is an appropriate method for brief studies of septal-ethanol interactions.
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Beatty, W. W., & Schwartzbaum, J. S. Enhanced reactivity to quinine and saccharin solutions following septal lesions in the rat. Psychonomic Science, 1967, 8, 483–484.
Beatty, W. W., & Schwartzbaum, J. S. Consummatory behavior for sucrose following septal lesions in the rat. Journal of Comparative and Physiological Psychology, 1968, 65, 93–102.
Cox, W. M. Simultaneous incentive contrast effects with alcoholic and nonalcoholic beverages as the discriminanda for reward magnitude. Physiological Psychology, 1981, 9, 276–280.
Eckardt, M. J., Skurdal, A. J., & Brown, J. S. Conditioned taste aversion produced by low doses of alcohol. Physiological Psychology, 1974, 2, 89–92.
Harvey, J. A., Heller, A., Moore, R. Y., Hunt, H. F., & Roth, L. J. Effect of central nervous system lesions on barbiturate sleeping time in the rat. Journal of Pharmacology and Experimental Therapeutics, 1964, 144, 24–36.
Himwich, H. E., DiPerri, R., Dravid, A., & Schweigerdt, A. Comparative susceptibility to alcohol of the cortical area and midbrain reticular formation of the cat. Psychosomatic Medicine, 1966, 28, 458–463.
Kalant, H. The pharmacology of alcohol intoxication. Quarterly Journal of Studies on Alcohol, 1961, 22, 1–23.
Kemble, E. D., & Nagel, J. A. Persistent depression of rearing behavior in rats after extensive septal lesions. Journal of Comparative and Physiological Psychology, 1975, 89, 747–758.
Ley, M. F., & Crow, L. T. The effects of alcohol on learned helplessness. Physiological Psychology, 1979, 7, 387–390.
Meyers, R. D., & Veale, W. L. The determinants of alcohol preference in animals. In B. Kissin & H. Begleiter (Eds.), The biology of alcoholism (Vol. 2): Physiology and behavior. New York: Plenum, 1972.
St.-Laurent, J. Brain centers of reinforcement and the effects of alcohol. In B. Kissin & H. Begleiter (Eds.), The biology of alcoholism (Vol. 2): Physiology and behavior. New York: Plenum, 1972.
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Phillip R. Godding is now a graduate student at North Dakota State University.
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Godding, P.R., Kemble, E.D. & Cox, W.M. The effect of septal lesions on ethanol consumption by rats. Bull. Psychon. Soc. 19, 301–302 (1982). https://doi.org/10.3758/BF03330264
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DOI: https://doi.org/10.3758/BF03330264