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Dopamine: Go/No-Go motivation versus switching

Published online by Cambridge University Press:  01 June 1999

Robert D. Oades
Affiliation:
Biological Psychiatry Research Group, University Psychiatry Clinics, University of Essen, 45147 Essen, Germanyoades@uni-essen.de www.uni-essen.de/schizophrenia

Abstract

Sensitivity to incentive motivation has a formative influence on extraversion. Mesoamygdaloid dopamine (DA) activity may, at one level, act as a micro-gate permitting an incentive to influence behavioral organization – “Go/No-Go” in this scheme. Data on function elsewhere in the mesocorticolimbic DA system are taken to support this particular function. At another level of analysis, the data in Depue & Collins's review, along with those on the rest of the ventral tegmental area (VTA) system, may fit better with a “switching” function in information processing. This link is supported by correlations between measures of extraversion, learned inattention, and overall DA activity. The point is extended to the novelty-seeking feature of the extraverted personality.

Type
Open Peer Commentary
Copyright
© 1999 Cambridge University Press

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