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red: adhd under the “micro-scope” of the rat model

Published online by Cambridge University Press:  07 September 2005

katya rubia
katya rubia
Affiliation:
department of child psychiatry, institute of psychiatry, london, se5 8af, united kingdomk.rubia@iop.kcl.ac.uk www.iop.kcl.ac.uk
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Abstract

derived from a rat model, the theory of sagvolden et al. offers an all-explanatory model of attention-deficit/hyperactivity disorder (adhd) anatomy, behaviour, and cognition as being caused predominantly by a hypo-dopaminergic mesolimbic (affecting the mesocortical and nigrostriatal) system, leading to abnormal reward and extinction processes. this model suffers from oversimplification and reductionism, reflecting the limitations of the use of animal models to explain higher mental disorders.

Type
open peer commentary
Information
Behavioral and Brain Sciences , Volume 28 , Issue 3 , June 2005 , pp. 439 - 440
Copyright
© 2005 cambridge university press

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