From PhilPapers forum Epistemology:

2009-05-04
Essential Epistemology: 1900-1950
Hi Kyle,

I would say Popper's 'The Logic of Scientific Discovery,' published in German in 1934, though not published in English until 1959. He offers a radically different conception of the subject in that he sees knowledge as social, inherently fallbile, completley unjustifiable but testable, and empirical though irremediably theory-laden. In my view, he revolutionised epistemology; but few people seem to have noticed.

Danny