|Abstract||Multi-voxel pattern analysis (MVPA) is a popular analytical technique in neuroscience that involves identifying patterns in fMRI BOLD signal data that are predictive of task conditions. But the technique is also frequently used to make inferences about the regions of the brain that are most important to the tasks in question, and our analysis shows that this is a mistake. MVPA does not provide a reliable guide to what information is being used by the brain during cognitive tasks, nor where that information is. This is due in part to inherent run to run variability in the decision space generated by the classifier, but there are also several other issues, discussed below, that make inference from the characteristics of the learned models to relevant brain activity deeply problematic. These issues have significant implications both for many papers already published, and for how the field uses this technique in the future.|
|Keywords||No keywords specified (fix it)|
|Through your library||Only published papers are available at libraries|
Similar books and articles
Ido Erev (2001). On Accumulation of Information and Model Selection. Behavioral and Brain Sciences 24 (3):406-407.
Andrew A. Fingelkurts & Alexander A. Fingelkurts (2011). Persistent Operational Synchrony Within Brain Default-Mode Network and Self-Processing Operations in Healthy Subjects. Brain and Cognition 75 (2):79-90.
Nancy A. Zook & Deana B. Davalos (2006). Can Fluid and General Intelligence Be Differentiated in an Older Adult Population? Behavioral and Brain Sciences 29 (2):143-145.
Linda D. Lerner & Gerald E. Fryxell (1988). An Empirical Study of the Predictors of Corporate Social Performance: A Multi-Dimensional Analysis. Journal of Business Ethics 7 (12):951 - 959.
Harry Howard (2003). Four Challenges for Cognitive Neuroscience and the Cortico-Hippocampal Division of Memory. Behavioral and Brain Sciences 26 (6):681-682.
Colin Klein (2010). Images Are Not the Evidence in Neuroimaging. British Journal for the Philosophy of Science 61 (2):265-278.
Guido Bugmann (1997). Binding by Synchronisation: A Task-Dependence Hypothesis. Behavioral and Brain Sciences 20 (4):685-686.
Bettina Sorger & Audrey Maudoux, Another Kind of 'BOLD Response': Answering Multiple-Choice Questions Via Online Decoded Single-Trial Brain Signals.
Stephen Gorard (2003). What Is Multi-Level Modelling For? British Journal of Educational Studies 51 (1):46 - 63.
Added to index2010-04-30
Total downloads21 ( #58,715 of 549,067 )
Recent downloads (6 months)1 ( #63,185 of 549,067 )
How can I increase my downloads?