Problems of reproducibility in complex mind-matter systems

Systems exhibiting relationships between mental states and material states, briefly mind-matter systems, offer epistemological and methodological problems exceeding those of systems with mental states or material states alone. Some of these problems can be addressed by proceeding from standard firstorder approaches to more sophisticated second-order approaches. These can illuminate questions of reference and validity, and their ramifications for the topic of reproducibility. For various situations in complex systems it is shown that second-order approaches need to be employed. Considering mind-matter systems as generalized complex systems provides some guidelines for analyzing the problem of reproducibility in such systems from a novel perspective.
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