A Defense of Syntax-Based Gene Concepts in Postgenomics: Genes as Modular Subroutines in the Master Genomic Program

Philosophy of Science 78 (5):712-723 (2011)
The purpose of this article is to update and defend syntax-based gene concepts. I show how syntax-based concepts can and have been extended to accommodate complex cases of processing and gene expression regulation. In response to difficult cases and causal parity objections, I argue that a syntax-based approach fleshes out a deflationary concept defining genes as genomic sequences and organizational features of the genome contributing to a phenotype. These organizational features are an important part of accepted molecular explanations, provide the theoretical basis for a large number of experimental techniques and practical applications, and play a crucial role in in annotating the genome, deriving predictions and constructing bioinformatics models
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DOI 10.1086/662261
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References found in this work BETA
Paul E. Griffiths & Karola Stotz (2006). Genes in the Postgenomic Era. Theoretical Medicine and Bioethics 27 (6):499-521.
Raphael Falk (1986). What is a Gene? Studies in History and Philosophy of Science Part A 17 (2):133-173.
Petter Portin (2002). Historical Development of the Concept of the Gene. Journal of Medicine and Philosophy 27 (3):257 – 286.

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