David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Acta Biotheoretica 39 (3-4):167-184 (1991)
We show how a simple nonlinear dynamical system (the discrete quadratic iteration on the unit segment) can be the basis for modelling the embryogenesis process. Such an approach, even though being crude, can nevertheless prove to be useful when looking with the two main involved processes:i) on one hand the cell proliferation under successive divisions ii) on the other hand, the differentiation between cell lineages. We illustrate this new approach in the case of Caenorhabditis elegans by looking at the early stages of embryogenesis, up to several hundreds of cells (lima bean larval stage). We show how the many results that have been obtained by several groups can be interpreted in terms of values for the parameters controlling the dynamical system. Furthermore, we can extend the model to the cases of genetic mutations. More precisely the teratogenetic and lethal effects are associated with abnormal variation of the control parameters with time
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Rachel A. Ankeny (2000). Fashioning Descriptive Models in Biology: Of Worms and Wiring Diagrams. Philosophy of Science 67 (3):272.
Nick Chater & Ulrike Hahn (1998). What is the Dynamical Hypothesis? Behavioral and Brain Sciences 21 (5):633-634.
Hannes Leitgeb (2005). Interpreted Dynamical Systems and Qualitative Laws: From Neural Networks to Evolutionary Systems. Synthese 146 (1-2):189 - 202.
Michael Wheeler (1998). An Appeal for Liberalism, or Why Van Gelder's Notion of a Dynamical System is Too Narrow for Cognitive Science. Behavioral and Brain Sciences 21 (5):653-654.
Sylvain Thibault, Laurent Heyer, Gila Benchetrit & Pierre Baconnier (2002). Ventilatory Support: A Dynamical Systems Approach. Acta Biotheoretica 50 (4):269-279.
Arciszewski Michal, Reducing the Dauer Larva: Molecular Models of Biological Phenomena in Caenorhabditis Elegans Research.
Soraya de Chadarevian (1998). Of Worms and Programmes: Caenorhabditis Elegans and the Study of Development. Studies in History and Philosophy of Science Part C 29 (1):81-105.
Scott F. Gilbert & Erik M. Jorgensen (1998). Wormwholes: A Commentary on K. F. Schaffner's "Genes, Behavior, and Developmental Emergentism". Philosophy of Science 65 (2):259-266.
S. Chadarevian (1998). Of Worms and Programmes: Caenorhabditis Elegans and the Study of Development. Studies in History and Philosophy of Science Part C 29 (1):81-105.
Kenneth F. Schaffner (2000). Behavior at the Organismal and Molecular Levels: The Case of C. Elegans. Philosophy of Science 67 (3):288.
Added to index2009-01-28
Total downloads9 ( #177,741 of 1,410,137 )
Recent downloads (6 months)3 ( #75,890 of 1,410,137 )
How can I increase my downloads?