Benefits to research subjects in international trials: Do they reduce exploitation or increase undue inducement?
Developing World Bioethics 8 (3):178-191 (2008)
| Abstract | There is an alleged tension between undue inducement and exploitation in research trials. This paper considers claims that increasing the benefits to research subjects enrolled in international, externally-sponsored clinical trials should be avoided on the grounds that it may result in the undue inducement of research subjects. This article contributes to the debate about exploitation versus undue inducement by introducing an analysis of the available empirical research into research participants' motivations and the influence of payments on research subjects' behaviour and risk assessment. Admittedly, the available research in this field is limited, but the research that has been conducted suggests that financial rewards do not distort research subjects' behaviour or blind them to the risks involved with research. Therefore, I conclude that research sponsors should prioritise the prevention of exploitation in international research by providing greater benefits to research participants. (edited) | |||||||||
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Segun Gbadegesin & David Wendler (2006). Protecting Communities in Health Research From Exploitation. Bioethics 20 (5):248-253.
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Angela Ballantyne (2008). 'Fair Benefits' Accounts of Exploitation Require a Normative Principle of Fairness: Response to Gbadegesin and Wendler, and Emanuel Et Al. Bioethics 22 (4):239–244.
Christine Grady (2001). Money for Research Participation: Does It Jeopardize Informed Consent? American Journal of Bioethics 1 (2):40 – 44.
Jeremy Snyder (2010). Multiple Forms of Exploitation in International Research: The Need for Multiple Standards of Fairness. American Journal of Bioethics 10 (6):40-41.
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Betty Kwagala, Douglas Wassenaar & Julius Ecuru (2010). Payments and Direct Benefits in Hiv/Aids Related Research Projects in Uganda. Ethics and Behavior 20 (2):95 – 109.
Trisha Phillips (2011). Exploitation in Payments to Research Subjects. Bioethics 25 (4):209-219.
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