The hodgkin‐huxley equations and the concrete model: Comments on Craver, Schaffner, and Weber
Philosophy of Science 75 (5):1034-1046 (2008)
| Abstract | I claim that the Hodgkin‐Huxley (HH) current equations owe a great deal of their importance to their role in bringing results from experiments on squid giant action preparations to bear on the study of the action potential in other neurons in other in vitro and in vivo environments. I consider ideas from Weber and Craver about the role of Coulomb’s and other fundamental equations in explaining the action potential and in HH’s development of their equations. Also, I offer an embellishment to Schaffner’s emergent unifier conception of the HH model. †To contact the author, please write to: Department of HPS, University of Pittsburgh, 1017 Cathedral of Learning, Pittsburgh, PA 15260; e‐mail: rtjbog@comcast.net. | |||||||||
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Ulrich M.�Ller & Stephan Pilatus (1982). On Hodgkin and Huxley's Theory of Excitable Membranes. Metamedicine 3 (2):193-208.
F. Tudoret, A. Bardou & G. Carrault (2001). Numerically Solving Physiological Models Based on a Polynomial Approach. Acta Biotheoretica 49 (4).
Carl F. Craver (2009). Explaining the Brain. OUP Oxford.
Carl F. Craver (2006). When Mechanistic Models Explain. Synthese 153 (3):355-376.
Marcel Weber (2008). Causes Without Mechanisms: Experimental Regularities, Physical Laws, and Neuroscientific Explanation. Philosophy of Science 75 (5):995-1007.
Kenneth F. Schaffner (2008). Theories, Models, and Equations in Biology: The Heuristic Search for Emergent Simplifications in Neurobiology. Philosophy of Science 75 (5):1008-1021.
Carl F. Craver (2008). Physical Law and Mechanistic Explanation in the Hodgkin and Huxley Model of the Action Potential. Philosophy of Science 75 (5):1022-1033.
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