David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Ezio Di Nucci
Jonathan Jenkins Ichikawa
Jack Alan Reynolds
Learn more about PhilPapers
Acta Biotheoretica 29 (1):1-35 (1980)
The principles of automation (automatism and programming) in the unfolding of spatio-temporal patterns during animal development are deduced from experimental data reconsidered from the point of view of cell sociology. The developmental programme in the egg is not part of the genetic information but a part of the cytoplasmic information. Throughout development cells store extra-cellular information released by their neighbours in the form of cytoplasmic information. Successive determinations cannot be considered as successive reprogrammings of cells: each one consists of a selection of one specific programme from the total information previously stored. This programme specifies cell interactions in the determined population as a whole; it is very imprecise and is progressively completed during the course of further differentiation by information released by neighbouring cell populations. Complicated patterns may emerge from only two homogeneous populations involved in distinct differentiation pathways and confronting each other. Consequently the egg developmental programme provides gene effectors and specific physico-chemical conditions necessary for the starting of at least two distinct differentation pathways. Experimental data suggest that there are two components in this programme. One is a molecular machinery which starts at fertilization in the whole cytoplasm. It yields two programmes of differentiation, typically first an endodermal and then an ectodermal one. The other component of the egg developmental programme, which does not require specific information, allows the interception of the first (endodermal) programme. The application of informatics to developmental automatism is discussed in the latter part of the paper.
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Claus Emmeche (1999). The Sarkar Challenge to Biosemiotics: Is There Any Information in a Cell? Semiotica 127 (1-4):273-294.
Paul E. Griffiths (2001). Genetic Information: A Metaphor in Search of a Theory. Philosophy of Science 68 (3):394-412.
Robert E. Powell, Don C. Locke & Norman A. Sprinthall (1991). Female Offenders and Their Guards: A Programme to Promote Moral and Ego Development of Both Groups. Journal of Moral Education 20 (2):191-203.
William Bechtel (2007). In Search of Mitochondrial Mechanisms: Interfield Excursions Between Cell Biology and Biochemistry. Journal of the History of Biology 40 (1):1 - 33.
MiloŠ Jílek (1975). Stochastic Development of Cell Populations Under Non-Homogeneous Conditions. Acta Biotheoretica 24 (3-4):108-119.
G. M. Innocenti (1997). “Differentiationism” Can Reconcile Selectionism and Constructivism. Behavioral and Brain Sciences 20 (4):568-569.
Rosine Chandebois & Jacob Faber (1987). From DNA Transcription to Visible Structure: What the Development of Multicellular Animals Teaches Us. Acta Biotheoretica 36 (2):61-119.
Rosine Chandebois (1977). Cell Sociology and the Problem of Position Effect: Pattern Formation, Origin and Role of Gradients. Acta Biotheoretica 26 (4):203-238.
Rosine Chandebois (1981). The Problem of Automation in Animal Development: Confrontation of the Concept of Cell Sociology with Biochemical Data. Acta Biotheoretica 30 (3):143-169.
Added to index2009-01-28
Total downloads14 ( #314,367 of 1,941,077 )
Recent downloads (6 months)1 ( #458,098 of 1,941,077 )
How can I increase my downloads?