David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Kennedy Institute of Ethics Journal 22 (3):243-261 (2012)
The transition of novel and potentially promising medical therapies into their initial human clinical trials can engender conflicting pressures. On the one side, because Phase I trials raise greater ethical and human protection challenges than later stage clinical trials, there is a need to proceed cautiously. This is particularly the case for Phase I trials with a novel therapy being tested in humans for the first time, usually termed first-in-human (FIH) trials, especially if the FIH trial involves significant risks. On the other side, scientists interested in having their research validated, corporations with a financial interest in the field, and potential patients and patient support groups desirous of having ..
|Keywords||info:mesh/Oligodendroglia info:mesh/Embryonic Stem Cells info:mesh/United States info:mesh/Clinical Trials as Topic info:mesh/Stem Cell Transplantation info:mesh/Humans info:mesh/United States Food and Drug Administration info:mesh/Investigational New Drug Application info:mesh/Spinal Cord Injuries Oligodendroglia Animals Humans Spinal Cord Injuries Disease Models, Animal Stem Cell Transplantation Investigational New Drug Application United States Food and Drug Administration United States Embryonic Stem Cells Clinical Trials as Topic Stem Cell Research info:mesh/Animals info:mesh/Stem Cell Research info:mesh/Disease Models, Animal|
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