David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Ezio Di Nucci
Jack Alan Reynolds
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Journal of Law, Medicine & Ethics 36 (2):280-285 (2008)
Human genetic and genomic research can yield information that may be of clinical relevance to the individuals who participate as subjects of the research. It has been common practice among researchers to notify participants during the informed consent process that no individual results will be disclosed, “incidental” or otherwise. However, as genetic information obtained in research becomes orders of magnitude more voluminous, increasingly accessible online, and more informative, this precedent may no longer be appropriate. There is not yet consensus on the responsibilities of researchers to disclose individual research results to research participants. Empirical research suggests that participants want to know individual research results. On the other hand, the increased resolution and power aforded by new genomic analyses may lead to fndings of statistical, but not necessarily clinical, signifcance. This paper addresses the issues to be considered in deciding whether and how to disclose “incidental” fndings or other fndings of clinical signifcance that arise in the course of human genomic and genetic research. What research results should be ofered, and what should not be ofered? For which research should individual results be ofered to research participants, when should they be ofered, how, and to whom?
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Citations of this work BETA
Catherine Gliwa & Benjamin E. Berkman (2013). Do Researchers Have an Obligation to Actively Look for Genetic Incidental Findings? American Journal of Bioethics 13 (2):32-42.
Susan M. Wolf, Jordan Paradise & Charlisse Caga-Anan (2008). The Law of Incidental Findings in Human Subjects Research: Establishing Researchers' Duties. Journal of Law, Medicine & Ethics 36 (2):361-383.
Lisa Eckstein, Jeremy R. Garrett & Benjamin E. Berkman (2014). A Framework for Analyzing the Ethics of Disclosing Genetic Research Findings. Journal of Law, Medicine & Ethics 42 (2):190-207.
Ma'N. H. Zawati & Amélie Rioux (2011). Biobanks and the Return of Research Results: Out with the Old and In with the New? Journal of Law, Medicine & Ethics 39 (4):614-620.
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