Much more than a gene: hereditary breast and ovarian cancer, reproductive choices and family life [Book Review]
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Medicine, Health Care and Philosophy 16 (2):231-244 (2013)
This article presents the results of a study that investigates the way in which carriers of a mutation on the BRCA1 or the BRCA2 gene, associated with a high risk of breast and ovarian cancer, make their reproductive decisions. Using semi-structured interviews, the study explored the way in which these persons reflected on the acceptability of taking the risk of transmitting this mutation to the next generation, the arguments they used in favor or against taking that risk, and in the light of these arguments, their opinion on the acceptability of preimplantation genetic diagnosis (PGD) as a reproductive option. The findings suggest that when carriers are planning to have a(nother) child, they are mainly concerned by the risk of transmitting ‘much more than a gene’: essentially painful experiences not only with respect to health, such as undergoing cancer surveillance or combatting one’s own illness, but also with regards to family life, such as witnessing the illness and death of a close relative, encountering difficulties in finding a partner or reconsidering one’s plans to have a family. As for opinions concerning the acceptability of PGD as a reproductive option, opinions about personal recourse were varied but all expressed the understanding that PGD should be made available to those persons who consider it their best option
|Keywords||Duties to family Genetic predisposition to cancer Genetic testing Hereditary breast and ovarian cancer Preimplantation genetic diagnosis (PGD) Reproductive choices|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
N. Hallowell (2003). Balancing Autonomy and Responsibility: The Ethics of Generating and Disclosing Genetic Information * Commentary * Author's Reply. Journal of Medical Ethics 29 (2):74-79.
Citations of this work BETA
No citations found.
Similar books and articles
Uwe Hartung, Sara Rubinelli & Peter J. Schulz (2011). “Your Risk is Low, Because …”: Argument-Driven Online Genetic Counselling. Argument and Computation 1 (3):199-214.
Megan Eide & Ann Milliken Pederson (2009). God, Disease, and Spiritual Dilemmas: Reading the Lives of Women with Breast Cancer. Zygon 44 (1):85-96.
Frances M. Alexakos, Attitudes of Rhode Island Primary Care Physicians Toward the Use of Genetic Testing for Breast Cancer.
Frances M. Alexakos (2003). Attitudes of Rhode Island Primary Care Physicians Toward the Use of Genetic Testing for Breast Cancer. Dissertation, Salve Regina University
Jeffrey P. Kahn & Anna C. Mastroianni (2004). Creating a Stem Cell Donor: A Case Study in Reproductive Genetics. Kennedy Institute of Ethics Journal 14 (1):81-96.
Laurie Zoloth, Leilah Backhus & Teresa Woodruff (2008). Waiting to Be Born: The Ethical Implications of the Generation of “Nuborn” and “Nuage” Mice From Pre-Pubertal Ovarian Tissue. American Journal of Bioethics 8 (6):21 – 29.
Roy Gilbar & Ora Gilbar (2009). The Medical Decision-Making Process and the Family: The Case of Breast Cancer Patients and Their Husbands. Bioethics 23 (3):183-192.
Knut Borch-Johnsen, Jørgen H. Olsen & Thorkild I. A. Sørensen (1994). Genes and Family Environment in Familial Clustering of Cancer. Theoretical Medicine and Bioethics 15 (4).
Rebecca Dresser (2011). Bioethics and Cancer: When the Professional Becomes Personal. Hastings Center Report 41 (6):14-18.
Stewart Justman (2012). Uninformed Consent: Mass Screening for Prostate Cancer. Bioethics 26 (3):143-148.
Ellen Matloff & Arthur Caplan (2008). Direct to Confusion: Lessons Learned From Marketing Brca Testing. American Journal of Bioethics 8 (6):5 – 8.
Jerry Menikoff (2006). What the Doctor Didn't Say: The Hidden Truth About Medical Research. Oxford University Press.
Jenny Slatman (2012). Phenomenology of Bodily Integrity in Disfiguring Breast Cancer. Hypatia 27 (2):281-300.
Lisa Campo-Engelstein & Sarah B. Rodriguez (2011). Two Chicks in a Lab with Eggs. Hastings Center Report 41 (3):21-23.
Lisa Bortolotti & Daniela Cutas (2009). Reproductive and Parental Autonomy: An Argument for Compulsory Parental Education. Reproductive Biomedicine Online 19 (ethics suppl.):5-14.
Added to index2011-11-03
Total downloads16 ( #98,987 of 1,096,734 )
Recent downloads (6 months)1 ( #273,068 of 1,096,734 )
How can I increase my downloads?