Graduate studies at Western
Acta Biotheoretica (forthcoming)
|Abstract||The genetic code has evolved from its initial non-degenerate wobble version until reaching its present state of degeneracy. By using the stereochemical hypothesis, we revisit the problem of codon assignations to the synonymy classes of amino-acids. We obtain these classes with a simple classifier based on physico-chemical properties of nucleic bases, like hydrophobicity and molecular weight. Then we propose simple RNA (or more generally XNA, with X for D, P or R) ring structures that present, overlap included, one and only one codon by synonymy class as solutions of a combinatory variational problem. We compare these solutions to sequences of present RNAs considered as relics, with a high interspecific invariance, like invariant parts of tRNAs and micro-RNAs. We conclude by emphasizing some optimal properties of the genetic code.|
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
|Through your library||Configure|
Similar books and articles
L. Almeida & J. Demongeot (forthcoming). Predictive Power of “A Minima” Models in Biology. Acta Biotheoretica.
Alvaro Moreno Bergareche & Julio Fernandez Ostolaza (1992). From Records to Self-Description: The Role Played by RNA in Early Evolutive Systems. Acta Biotheoretica 40 (1).
Susie Fisher (2010). Are Rna Viruses Vestiges of an Rna World? Journal for General Philosophy of Science 41 (1):121-141.
Manfred Welti (1987). Phases of Degeneracy of the Genetic Code. Acta Biotheoretica 36 (2).
Josef Berger (1976). The Genetic Code and the Origin of Life. Acta Biotheoretica 25 (4).
Robersy Sánchez & Ricardo Grau (2006). A Novel Algebraic Structure of the Genetic Code Over the Galois Field of Four DNA Bases. Acta Biotheoretica 54 (1).
Julian Chela-Flores (1996). Ideas in Theoretical Biology Preservation of Relics From the RNA World Through Natural Selection, Symbiosis and Horizontal Gene Transfer. Acta Biotheoretica 44 (2).
David Penny (2005). An Interpretive Review of the Origin of Life Research. Biology and Philosophy 20 (4):633-671.
Ulrich E. Stegmann (2004). The Arbitrariness of the Genetic Code. Biology and Philosophy 19 (2):205-222.
Added to index2009-01-28
Total downloads3 ( #213,863 of 739,764 )
Recent downloads (6 months)0
How can I increase my downloads?