Randomised placebo-controlled trials and HIV-infected pregnant women in developing countries. Ethical imperialism or unethical exploitation
Bioethics 15 (4):289–311 (2001)
| Abstract | In this paper, I provide a brief summary of the context, outline the arguments for and against the controversial use of placebo controls, and focus on particular areas that I believe merit further discussion or clarification. On balance, I argue that the researchers failed in their duties to protect the best interests of their research subjects, and to promote distributive justice. I discuss the difficulties of obtaining valid consent in this research context, and argue that it is unethical to inform women of their 'HIV' status without at least offering them prophylactic treatment for their unborn children. (edited). | |||||||||
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Piotr Zaborowski & Adam Górski (2004). Informed Consent and the Use of Placebo in Poland: Ethical and Legal Aspects. Science and Engineering Ethics 10 (1).
Deborah Zion (1998). 'Moral Taint' or Ethical Responsibility? Unethical Information and the Problem of HIV Clinical Trials in Developing Countries. Journal of Applied Philosophy 15 (3):231–239.
Bridget G. Haire (2011). Because We Can: Clashes of Perspective Over Researcher Obligation in the Failed Prep Trials. Developing World Bioethics 11 (2):63-74.
R. Macklin (2010). Intertwining Biomedical Research and Public Health in HIV Microbicide Research. Public Health Ethics 3 (3):199-209.
Nancy E. Kass, Holly A. Taylor & Patricia A. King (1996). Harms of Excluding Pregnant Women From Clinical Research: The Case of HIV-Infected Pregnant Women. Journal of Law, Medicine and Ethics 24 (1):36-46.
David M. Kent, Mkaya Mwamburi, Richard A. Cash, Tracy L. Rabin & Michael L. Bennish (2003). Testing Therapies Less Effective Than the Best Current Standard: Ethical Beliefs in an International Sample of Researchers. American Journal of Bioethics 3 (2):28 – 33.
Jeremy Sugarman (2004). Using Empirical Data to Inform the Ethical Evaluation of Placebo Controlled Trials. Science and Engineering Ethics 10 (1).
Franklin G. Miller & Howard Brody (2002). What Makes Placebo-Controlled Trials Unethical? American Journal of Bioethics 2 (2):3 – 9.
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