Understanding contemporary genomics

Perspectives on Science 12 (3):320-338 (2004)
: Recent molecular biology has seen the development of genomics as a successor to traditional genetics. This paper offers an overview of the structure, epistemology, and (very briefly) history of contemporary genomics. A particular focus is on the question to what extent the genome contains, or is composed of, anything that corresponds to traditional conceptions of genes. It is concluded that the only interpretation of genes that has much contemporary scientific relevance is what is described as the "developmental defect" gene concept. However, developmental defect genes typically only correspond to general areas of the genome and not to precise chemical structures (nucleotide sequences). The parts of the genome to be identified for an account of the processes of normal development are highly diverse, little correlated with traditional genes, and act in ways that are highly dependent on the cellular and higher level environment. Despite its historical development out of genetics, genomics represents a radically different kind of scientific project
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1162/1063614042795435
 Save to my reading list
Follow the author(s)
My bibliography
Export citation
Find it on Scholar
Edit this record
Mark as duplicate
Revision history Request removal from index
Download options
PhilPapers Archive

Upload a copy of this paper     Check publisher's policy on self-archival     Papers currently archived: 15,974
External links
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library
References found in this work BETA
C. Kenneth Waters (1994). Genes Made Molecular. Philosophy of Science 61 (2):163-185.

Add more references

Citations of this work BETA
Thomas A. C. Reydon (2009). Gene Names as Proper Names of Individuals: An Assessment. British Journal for the Philosophy of Science 60 (2):409-432.

View all 6 citations / Add more citations

Similar books and articles
C. Kenneth Waters (1994). Genes Made Molecular. Philosophy of Science 61 (2):163-185.
John Dupre (2004). Understanding Contemporary Genomics. Perspectives on Science 12 (3):320-338.
Holmes Rolston (2006). What is a Gene? From Molecules to Metaphysics. Theoretical Medicine and Bioethics 27 (6):471-497.
Catherine Kendig, Reconstructing the Concept of Homology for Genomics. Pittsburgh/London Colloquium on Philosophy of Biology and Neuroscience, University of London. Online at PhilSci Archive.

Monthly downloads

Added to index


Total downloads

31 ( #101,479 of 1,725,806 )

Recent downloads (6 months)

3 ( #210,647 of 1,725,806 )

How can I increase my downloads?

My notes
Sign in to use this feature

Start a new thread
There  are no threads in this forum
Nothing in this forum yet.