Evolutionary Chance Mutation: A Defense of the Modern Synthesis' Consensus View

Abstract Biologists usually agree that all genetic mutations occur by “chance” or at “random” with respect to adaptation. The claim dates back to Darwin’s conception of “spontaneous,” “accidental” or “chance” variation (Darwin 1859, 1868; Darwin and Seward 1903). The Modern Synthesis later redefined Darwin’s idea as rooted in the phenomenon of genetic mutation following a long period of controversy over the “chance” vs “directed” character of variation
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