David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Biological Theory 2 (2):183-188 (2007)
The progress of the molecular biosciences has been so enormous that a discipline studying how cellular functioning emerges out of the behaviors of their molecular constituents has become reality. Systems biology studies cells as spatiotemporal networks of interacting molecules using an integrative approach of theory , experimental biology , and quantitative network-wide analytical measurement . Its aim is to understand how molecules jointly bring about life. Systems biology is rapidly discovering principles governing the functioning of molecular networks and methods to model and measure them. The application of the conceptual strength of systems sciences such as physics and engineering are opening up new ways of experimentally studying the design and functioning of molecular networks. Typically, in such studies models are used to highlight principles, design experiments, or to act in a predictive mode to specifically modify cellular behavior. In this trend article, theoretical approaches being applied in systems biology will be discussed. A number of books have recently appeared that deal with theoretical aspects of systems biology. In this article they are highlighted to facilitate the communication of systems biology to a broader audience
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
F. J. Bruggeman, H. V. Westerhoff & F. C. Boogerd (2002). Biocomplexity: A Pluralist Research Strategy is Necessary for a Mechanistic Explanation of the "Live" State. Philosophical Psychology 15 (4):411 – 440.
Citations of this work BETA
No citations found.
Similar books and articles
Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.) (2007). Systems Biology: Philosophical Foundations. Elsevier.
Philippe De Backer, Danny De Waele & Linda Van Speybroeck (2010). Ins and Outs of Systems Biology Vis-À-Vis Molecular Biology: Continuation or Clear Cut? Acta Biotheoretica 58 (1).
Jonathan F. Davies & Maureen A. O'Malley (2007). Toward a Philosophy of Systems Biology: Systems Biology: Philosophical Foundations, Fred C. Boogerd , Frank J. Bruggeman , Jan-Hendrik S. Hofmeyr , and Hans V. Westerhoff , Eds. Amsterdam: Elsevier, 2007, (360 Pp; €99.95 Hbk; ISBN 978-0-444-52085-2). [REVIEW] Biological Theory 2 (4):420-422.
William Morton Wheeler (1939/1967). Essays in Philosophical Biology. New York, Russell & Russell.
Fred C. Boogerd, Frank J. Bruggeman & Robert C. Richardson (2013). Mechanistic Explanations and Models in Molecular Systems Biology. Foundations of Science 18 (4):725-744.
Trevon Fuller (2003). The Integrative Biology of Phenotypic Plasticity. Biology and Philosophy 18 (2):381-389.
Massimo Pigliucci (2003). From Molecules to Phenotypes? The Promise and Limits of Integrative Biology. Basic and Applied Ecology 4:297-306.
Shintaro Azechi (2005). Informational Humidity Model: Explanation of Dual Modes of Community for Social Intelligence Design. [REVIEW] AI and Society 19 (1):110-122.
Athel Cornish-Bowden (2006). Putting the Systems Back Into Systems Biology. Perspectives in Biology and Medicine 49 (4):475-489.
Claudio Gutiérrez, Sebastián Jaramillo & Jorge Soto-Andrade (2011). Some Thoughts on A. H. Louie's “More Than Life Itself: A Reflection on Formal Systems and Biology”. [REVIEW] Axiomathes 21 (3):439-454.
Ulrich Krohs (2006). Philosophies of Particular Biological Research Programs. Biological Theory 1 (2):182-187.
Andreas Wagner (1999). Causality in Complex Systems. Biology and Philosophy 14 (1):83-101.
Maximilian Hörner, Nadine Reischmann & Wilfried Weber (2013). Synthetic Biology: Programming Cells for Biomedical Applications. Perspectives in Biology and Medicine 55 (4):490-502.
Jay Odenbaugh (2006). The Strategy of “the Strategy of Model Building in Population Biology”. Biology and Philosophy 21 (5):607-621.
Michael Boylan (1982). The Digestive and "Circulatory" Systems in Aristotle's Biology. Journal of the History of Biology 15 (1):89 - 118.
Added to index2010-08-24
Total downloads9 ( #183,760 of 1,692,205 )
Recent downloads (6 months)1 ( #184,284 of 1,692,205 )
How can I increase my downloads?