David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Foundations of Chemistry 11 (1):33-42 (2009)
In the last years there has been a great improvement in the development of computational methods for combinatorial chemistry applied to drug discovery. This approach to drug discovery is sometimes called a “rational way” to manage a well known phenomenon in chemistry: serendipity discoveries. Traditionally, serendipity discoveries are understood as accidental findings made when the discoverer is in quest for something else. This ‘traditional’ pattern of serendipity appears to be a good characterization of discoveries where “luck” plays a key role. In this sense, some initial failures in combinatorial chemistry are frequently attributed to a naïf appropriation of a “serendipity model” for discovery (a “serendipity mistake”). In this paper we try to evaluate this statement by criticizing its foundations. It will be suggested that the notion of serendipity has different aspects and that the criticism to the first attempts could be understood as a “serendipity mistake.” We will suggest that “serendipity” strategies, a kind of blind search, can be seen sometimes as a “genuine part” of scientific practice. A discussion will ensue about how this characterization can give us a better understanding of some aspects of serendipity discoveries.
|Keywords||Discovery Combinatorial chemistry Serendipity|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
Aharon Kantorovich (1993). Scientific Discovery: Logic and Tinkering. State University of New York Press.
Citations of this work BETA
No citations found.
Similar books and articles
Ronald Sousa (1998). Desire and Serendipity. Midwest Studies in Philosophy 22 (1):120-134.
Matthias Adam (2011). Multi-Level Complexities in Technological Development: Competing Strategies for Drug Discovery. In. In M. Carrier & A. Nordmann (eds.), Science in the Context of Application. Springer. 67--83.
Natasha Guinan (2001). Serendipity. Philosophy and Geography 4 (2):139 – 140.
Paul Thagard (2002). Curing Cancer? Patrick Lee's Path to the Reovirus Treatment. International Studies in the Philosophy of Science 16 (1):79 – 93.
Pek Van Andel (1994). Anatomy of the Unsought Finding. Serendipity: Origin, History, Domains, Traditions, Appearances, Patterns and Programmability. British Journal for the Philosophy of Science 45 (2):631-648.
Pek Van Andel (1994). Anatomy of the Unsought Finding. Serendipity: Origin, History, Domains, Traditions, Appearances, Patterns and Programmability. British Journal for the Philosophy of Science 45 (2):631 - 648.
Mark de Rond & Iain Morley (eds.) (2010). Serendipity: Fortune and the Prepared Mind. Cambridge University Press.
Toby J. Sommer (2001). Suppression of Scientific Research: Bahramdipity and Nulltiple Scientific Discoveries. Science and Engineering Ethics 7 (1):77-104.
Added to index2009-01-28
Total downloads45 ( #38,133 of 1,103,219 )
Recent downloads (6 months)8 ( #29,862 of 1,103,219 )
How can I increase my downloads?