Comparing Boolean and Piecewise Affine Differential Models for Genetic Networks

Acta Biotheoretica 58 (2):217-232 (2010)
Abstract
Multi-level discrete models of genetic networks, or the more general piecewise affine differential models, provide qualitative information on the dynamics of the system, based on a small number of parameters (such as synthesis and degradation rates). Boolean models also provide qualitative information, but are based simply on the structure of interconnections. To explore the relationship between the two formalisms, a piecewise affine differential model and a Boolean model are compared, for the carbon starvation response network in E. coli . The asymptotic dynamics of both models are shown to be quite similar. This study suggests new tools for analysis and reduction of biological networks
Keywords No keywords specified (fix it)
Categories (categorize this paper)
Options
 Save to my reading list
Follow the author(s)
My bibliography
Export citation
Find it on Scholar
Edit this record
Mark as duplicate
Revision history Request removal from index Translate to english
 
Download options
PhilPapers Archive


Upload a copy of this paper     Check publisher's policy on self-archival     Papers currently archived: 10,986
External links
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library
References found in this work BETA

No references found.

Citations of this work BETA

No citations found.

Similar books and articles
Ehud Lamm (2009). Conceptual and Methodological Biases in Network Models. Annals of the New York Academy of Sciences 1178:291-304.
Stellan Ohlsson (2000). Localist Models Are Already Here. Behavioral and Brain Sciences 23 (4):486-487.
Analytics

Monthly downloads

Sorry, there are not enough data points to plot this chart.

Added to index

2010-07-31

Total downloads

2 ( #348,296 of 1,100,983 )

Recent downloads (6 months)

2 ( #176,807 of 1,100,983 )

How can I increase my downloads?

My notes
Sign in to use this feature


Discussion
Start a new thread
Order:
There  are no threads in this forum
Nothing in this forum yet.