Differentiation of wing epidermal scale cells in a butterfly under the lateral inhibition model - appearance of large cells in a polygonal pattern
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Acta Biotheoretica 48 (2):121-136 (2000)
Cellular pattern formations of some epithelia are believed to be governed by the direct lateral inhibition rule of cell differentiation. That is, initially equivalent cells are all competent to differentiate, but once a cell has differentiated, the cell inhibits its immediate neighbors from following this pathway. Such a differentiation repeats until all non-inhibited cells have differentiated. The cellular polygonal patterns can be characterized by the numbers of undifferentiated cells and differentiated ones. When the differentiated cells become large in size, the polygonal pattern is deformed since more cells are needed to enclose the large cell. An actual example of such a cellular pattern was examined. The pupal wing epidermis of a butterfly Pieris rapae shows a transition of the equivalent-size cell pattern to the pattern involving large cells. The process of the transition was analyzed by using the method of weighted Voronoi tessellation that is useful for treatment of irregularly sized polygons. The analysis supported that the pattern transition of the early stage of the pupal wing epidermis is governed by the lateral inhibition rule. The differentiation takes place in order of largeness, but not smallness, of the apical polygonal area in the differentiating region of the pupal wing.
|Keywords||Philosophy Philosophy of Biology Evolutionary Biology|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Alexander Pruss, Cooperation with Past Evil and Use of Cell-Lines Derived From Aborted Fetuses Alexander R. Pruss May 25, 2004.
Mark T. Brown (2009). Moral Complicity in Induced Pluripotent Stem Cell Research. Kennedy Institute of Ethics Journal 19 (1):pp. 1-22.
Nicolas Rivier, Gudrun Schliecker & Benoît Dubertret (1995). The Stationary State of Epithelia. Acta Biotheoretica 43 (4):403-423.
Larry A. Taber (2000). Pattern Formation in a Nonlinear Membrane Model for Epithelial Morphogenesis. Acta Biotheoretica 48 (1):47-63.
M. Aubert, M. Badoual & B. Grammaticos (2008). A Model for Short- and Long-Range Interactions of Migrating Tumour Cell. Acta Biotheoretica 56 (4):297-314.
José Pierrez & Xavier Ronot (1992). Flow Cytometric Analysis of the Cell Cycle: Mathematical Modeling and Biological Interpretation. Acta Biotheoretica 40 (2-3):131-137.
Antónia Monteiro, Vernon French, Gijs Smit, Paul M. Brakefield & Johan A. J. Metz (2001). Butterfly Eyespot Patterns: Evidence for Specification by a Morphogen Diffusion Gradient. Acta Biotheoretica 49 (2):77-88.
Robert W. Korn (1993). Apical Cells as Meristems. Acta Biotheoretica 41 (3):175-189.
Rosine Chandebois (1977). Cell Sociology and the Problem of Position Effect: Pattern Formation, Origin and Role of Gradients. Acta Biotheoretica 26 (4):203-238.
D. Manoussaki, S. R. Lubkin, R. B. Vemon & J. D. Murray (1996). A Mechanical Model for the Formation of Vascular Networks in Vitro. Acta Biotheoretica 44 (3-4):271-282.
Added to index2009-01-28
Total downloads8 ( #192,297 of 1,410,151 )
Recent downloads (6 months)0
How can I increase my downloads?